• Title/Summary/Keyword: F127

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Peripheral Nerve Regeneration by Asymmetrically Porous PLGA/Pluronic F127 Nerve Guide Conduit

  • Oh, Se-Heang;Kim, Jun-Ho;Song, Kyu-Sang;Jeon, Byeong-Hwa;Lee, Il-Woo;Lee, Jin-Ho
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.181-181
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    • 2006
  • We developed a novel method to fabricate a nerve guide conduit (NGC) with the porosity of submicron pore sizes (to prevent fibrous tissue infiltration) and hydrophilicity (for effective oxygen and nutrient permeation) using poly(lactic-co-glycolic acid) (PLGA) and Pluronic F127 by a modified immersion precipitation method designed by our laboratory. It was recognized that the hydrophilized PLGA/F127 (3 wt%) tube can be a good candidate as a NGC from the analyses of its morphology, mechanical strength, hydrophilicity, model nutrient permeability and in vivo nerve regeneration behavior using a rat model.

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OSTEOGENIC ACTIVITY OF CULTURED HUMAN PERIOSTEAL-DERIVED CELLS IN A THREE DIMENSIONAL POLYDIOXANONE/PLURONIC F127 SCAFFOLD (Polydioxanone/pluronic F127 담체에 유입된 골막기원세포의 조골활성)

  • Lee, Jin-Ho;Oh, Se-Heang;Park, Bong-Wook;Hah, Young-Sool;Kim, Deok-Ryong;Kim, Uk-Kyu;Kim, Jong-Ryoul;Byun, June-Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.31 no.6
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    • pp.478-484
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    • 2009
  • Three-dimensional porous scaffolds play an important role in tissue engineering strategies. They provide a void volume in which vascularization, new tissue formation, and remodeling can occur. Like any grafted materials, the ideal scaffold for bone tissue engineering should be biocompatible without causing an inflammatory response. It should also possess biodegradability, which provides a suitable three-dimensional environment for the cell function together with the capacity for gradual resorption and replacement by host bone tissue. Various scaffolds have already been developed for bone tissue engineering applications, including naturally derived materials, bioceramics, and synthetic polymers. The advantages of biodegradable synthetic polymers include the ability to tailor specific functions. The purpose of this study was to examine the osteogenic activity of periosteal-derived cells in a polydioxanone/pluronic F127 scaffold. Periosteal-derived cells were successfully differentiated into osteoblasts in the polydioxanone/pluronic F127 scaffold. ALP activity showed its peak level at 2 weeks of culture, followed by decreased activity during the culture period. Similar to biochemical data, the level of ALP mRNA in the periosteal-derived cells was also largely elevated at 2 weeks of culture. The level of osteocalcin mRNA was gradually increased during entire culture period. Calcium content was detactable at 1 week and increased in a time-dependent manner up to the entire duration of culture. Our results suggest that polydioxanone/pluronic F127 could be a suitable scaffold of periosteal-derived cells for bone tissue engineering.

Characteristics of mid-latitude field-aligned irregularities observed with VHF coherent scatter ionospheric radar over Korea

  • Yang, Tae-Yong;Kwak, Young-Sil;Kil, Hyosub;Park, Young-Deuk
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.127.1-127.1
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    • 2012
  • The 40.8-MHz VHF coherent scatter ionospheric radar, located in South Korea (Gyeryong, $36.18^{\circ}N$, $127.14^{\circ}E$), has been operating since December 2009 to investigate ionosphere E- and F-region field-aligned irregularities (FAIs) of mid-latitude. During the observation, we found E- and F-region FAIs appeared frequently: continuous echoes during the post-sunrise period and Quasi-Periodic (QP) echoes at nighttime for E region ; strong post-sunset and pre-sunrise FAIs for F region. The characteristics of E- and F-region FAIs are presented in terms of seasonal and local time variations of occurrence during December 2009 to August 2012. In addition, to investigate the correlation with geomagnetic activity to FAIs occurrence, we compared K-index variations to local time occurrence. It is worth to note our occurrence result since long term observation over several years in the mid-latitude has not yet been carried out.

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HYPONORMAL TOEPLITZ OPERATORS ON THE BERGMAN SPACE

  • Lee, Jong-Rak;Lee, You-Ho
    • Honam Mathematical Journal
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    • v.30 no.1
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    • pp.127-135
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    • 2008
  • In this paper we consider the hyponormality of Toeplitz operators $T_{\varphi}$ on the Bergman space $L^2_a(\mathbb{D})$ with symbol in the case of function f + $\overline{g}$ with polynomials f and g. We present some necessary conditions for the hyponormality of $T_{\varphi}$, under certain assumptions about the coefficients of ${\varphi}$.

A MODIFIED INEXACT NEWTON METHOD

  • Huang, Pengzhan;Abduwali, Abdurishit
    • Journal of applied mathematics & informatics
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    • v.33 no.1_2
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    • pp.127-143
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    • 2015
  • In this paper, we consider a modified inexact Newton method for solving a nonlinear system F(x) = 0 where $F(x):R^n{\rightarrow}R^n$. The basic idea is to accelerate convergence. A semi-local convergence theorem for the modified inexact Newton method is established and an affine invariant version is also given. Moreover, we test three numerical examples which show that the modified inexact scheme is more efficient than the classical inexact Newton strategy.

Scaling Rules for Multi-Finger Structures of 0.1-μm Metamorphic High-Electron-Mobility Transistors

  • Ko, Pil-Seok;Park, Hyung-Moo
    • Journal of electromagnetic engineering and science
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    • v.13 no.2
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    • pp.127-133
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    • 2013
  • We examined the scaling effects of a number of gate_fingers (N) and gate_widths (w) on the high-frequency characteristics of $0.1-{\mu}m$ metamorphic high-electron-mobility transistors. Functional relationships of the extracted small-signal parameters with total gate widths ($w_t$) of different N were proposed. The cut-off frequency ($f_T$) showed an almost independent relationship with $w_t$; however, the maximum frequency of oscillation ($f_{max}$) exhibited a strong functional relationship of gate-resistance ($R_g$) influenced by both N and $w_t$. A greater $w_t$ produced a higher $f_{max}$; but, to maximize $f_{max}$ at a given $w_t$, to increase N was more efficient than to increase the single gate_width.

BETA-EXPANSIONS WITH PISOT BASES OVER Fq((x-1))

  • Hbaib, Mohamed
    • Bulletin of the Korean Mathematical Society
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    • v.49 no.1
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    • pp.127-133
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    • 2012
  • It is well known that if the ${\beta}$-expansion of any nonnegative integer is finite, then ${\beta}$ is a Pisot or Salem number. We prove here that $\mathbb{F}_q((x^{-1}))$, the ${\beta}$-expansion of the polynomial part of ${\beta}$ is finite if and only if ${\beta}$ is a Pisot series. Consequently we give an other proof of Scheiche theorem about finiteness property in $\mathbb{F}_q((x^{-1}))$. Finally we show that if the base ${\beta}$ is a Pisot series, then there is a bound of the length of the fractional part of ${\beta}$-expansion of any polynomial P in $\mathbb{F}_q[x]$.

Adenosine Modulate the Oocyte Developmental Competence by Exposing Stages and Synthetic Blocking during In Vitro Maturation

  • Cheon, Yong-Pil
    • Development and Reproduction
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    • v.20 no.2
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    • pp.127-133
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    • 2016
  • Purine metabolism is known factor for nuclear maturation of oocytes through both follicle cells and oocyte itself. However, it is largely unknown the roles of purine metabolism in the oocyte competence for fertilization and early development. In this study, the effects of adenosine in oocyte competence for development were examined using adenosine and its synthetic inhibitors. Adenosine treatment from GV intact stage for 18 hr (fGV) caused of decrease the fertilization rate but of increase the cleavage rate compared from the other stage treatment groups. Hadacidin did not effect on fertilization rate but increased cleavage rate without stage specificity. Adenosine did not block the effects of hadacidin with the exception of fGV group. Inhibition of purine synthetic pathways the fertilization rate was decreased in the fGV and fGVB groups but increased in the fMII group. Exogenous adenosine caused of decrease fertilization rate in the fGVB group but increase in the fMII group. Cleavage rate was dramatically increased in the adenosine treatment with synthetic inhibitors. It means that the metabolism of purine has stage specific effects on fertilization and cleavage. Exogenous adenosine had only can improve oocyte developmental competence when it treated at GV intact stage. On the other hand, endogenous synthesis in all maturation stage cause of increase the cleavage rate without effects on fertilization. These data suggest that adenosine at GV stage as a paracrine fashion and inhibitions of endogenous adenosine in all stage improve oocyte developmental competence.