• Computers and Concrete
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• v.2 no.3
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• pp.203-214
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• 2005

In the Part 1 paper (Gawin, et al. 2005) some experimental results concerning micro-structural tests, permeability measurements and stress-strain tests of four types of High Performance Concrete, exposed to elevated temperatures (up to $700^{\circ}C$) are presented and discussed. On the basis of these experimental results parameters of the constitutive relationships describing influence of damage and temperature upon material intrinsic permeability at high temperature were determined. In this paper the effects of various formulations of damage-permeability coupling on results of computer simulations are analysed and compared with the results obtained by means of the previously proposed approach, that does not take into account the thermo-chemical concrete damage directly. Numerical solutions are obtained using the recently developed fully coupled model of hygro-thermal and damage phenomena in concrete at elevated temperatures. High temperature effects are considered by means of temperature and pressure dependence of several material parameters. Based on the mathematical model, the computer code HITECOSP was developed. Material parameters of the model were measured by several European laboratories, which participated in the "HITECO" research project. A model problem, concerning hygro-thermal behaviour and degradation of a HPC structure during fire, is solved. The influence of two different constitutive descriptions of the concrete permeability changes at high temperature, including thermo-chemical and mechanical damage effects, upon the results of computer simulations is analysed and discussed.

• The Journal of Korean Society of Virology
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• v.29 no.3
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• pp.165-174
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• 1999

To investigate viral pathogenesis and in vivo efficacy of acyclovir (ACV) in mouse HSV-1 encephalitis models, female BALB/c mice aged 5 weeks were inoculated with strain F either intranasally (IN) or intracerebrally (IC). ACV-treatment by intraperitomeal injection with 0, 5, 10 and 25 mg/kg b.i.d. for 6 days was commenced 1 h after infection. Body weight and signs of clinical disease were noted daily up to 2 weeks. $ED_{50}$ of ACV in IN infection was <5 mg/kg and 14.1 mg/kg in IC infection. Tissues of central nervous system were collected from 2 mice per group everyday up to 5 day p.i. and the virus titers were measured. In IN infection model, high titers in eyes and trigeminal nerves were observed. ACV-treatment showed significant reduction of the titers in all the isolated. In IC infection model, cerebrum, cerebellum and brain stem showed high virus titers. ACV-treatment showed less significant reduction of virus titers than that in IN infection model. Reactivation of explanted trigeminal nerves from mice 30 day p.i. was monitored. In all of ACV treated mice reactivation was observed, i.e. even the highest dose of ACV did not inhibit the establishment of viral latency.

• Korean Chemical Engineering Research
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• v.48 no.1
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• pp.110-115
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• 2010

The experiment was designed to compare pyrolysis kinetics of two different classes of imported coal. The pyrolysis behaviors of the coals were first observed with thermogravimetric analyzer(TGA). The kinetic analysis was further done based on a new distributed activation energy model(New DAEM). During the analysis, weight loss curves measured at three different heating rates were used to obtain the activation energy distribution function curve f(E) of a given coal sample where a mean activation energy is determined by its peak. The results show a significant difference in the mean activation energy between two coals for the pyrolytic reaction. The prediction of a chemical percolation devolatilization(CPD) model where the kinetics obtained from the New DAEM method were incorporated is in much closer agreement with an experimental data of TGA particularly for the bituminous coal.

• Nuclear Engineering and Technology
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• v.53 no.8
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• pp.2682-2695
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• 2021

This paper aims to evaluate the structural dynamic responses and damage/failure of the nuclear fuel reprocessing plant under the free drop impact of spent fuel cask (SFC) and fuel assembly (FA) during the on-site transportation. At the present Part I of this paper, the large-scale SFC model free drop test and the corresponding numerical simulations are performed. Firstly, a composite target which is composed of the protective structure, i.e., a thin RC plate (representing the inverted U-shaped slab in the loading shaft) and/or an autoclaved aerated concrete (AAC) blocks sacrificial layer, as well as a thick RC plate (representing the bottom slab in the loading shaft) is designed and fabricated. Then, based on the large dropping tower, the free drop test of large-scale SFC model with the mass of 3 t is carried out from the height of 7 m-11 m. It indicates that the bottom slab in the loading shaft could not resist the free drop impact of SFC. The composite protective structure can effectively reduce the damage and vibrations of the bottom slab, and the inverted U-shaped slab could relieve the damage of the AAC blocks layer dramatically. Furthermore, based on the finite element (FE) program LS-DYNA, the corresponding refined numerical simulations are performed. By comparing the experimental and numerical damage and vibration accelerations of the composite structures, the present adopted numerical algorithms, constitutive models and parameters are validated, which will be applied in the further assessment of drop impact effects of full-scale SFC and FA on prototype nuclear fuel reprocessing plant in the next Part II of this paper.

• International Journal of Naval Architecture and Ocean Engineering
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• v.13 no.1
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• pp.889-901
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• 2021

The tension of cables and motion response significantly affect safety of an immersed tunnel element in the immersion process. To investigate those, a hydrodynamic scale-model test was carried out and the model experiments was conducted under wind, current and wave loads simultaneously. The immersion standby (the process that the position of the immersed tunnel element should be located before the immersion process) and immersion process conditions have been conducted and illustrated. At the immersion standby conditions, the maximum force of the cables and motion is much larger at the side of incoming wind, wave and current, the maximum force of Element-6 (6 cables directly tie on the element) is larger than for Pontoon-8 (8 cables tie on pontoon of the element), and the flexible connection can reduce the maximum force of the mooring cables and motion of element (i.e. sway is expecting to decrease approximate 40%). The maximum force of the mooring cables increases with the increase of current speed, wave height, and water depth. The motion of immersed tunnel element increases with increase of wave height and water depth, and the current speed had little effect on it. At the immersion process condition, the maximum force of the cables decrease with the increase of immersion depth, and dramatically increase with the increase of wave height (i.e. the tension of cable F4 of pontoons at wave height of 1.5 m (83.3t) is approximately four times that at wave height of 0.8 m). The current speed has no much effect on the maximum force of the cables. The weight has little effect on the maximum force of the mooring cables, and the maximum force of hoisting cables increase with the increase of weight. The maximum value of six-freedom motion amplitude of the immersed tunnel element decreases with the increase of immersion depth, increase with the increase of current speed and wave height (i.e. the roll motion at wave height of 1.5 m is two times that at wave height of 0.8 m). The weight has little effect on the maximum motion amplitude of the immersed tunnel element. The results are significant for the immersion safety of element in engineering practical construction process.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.10 no.1
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• pp.170-178
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• 2000

Most of manufacturers try to produce the most efficient filter for respirators with the lowest breathing resistance. Filter performance depends on low penetration, i.e., high efficiency (%), and low pressure drop ($mmH_2O$). This study was performed to evaluate performance of respirator filters by quality factor ($q_F$) and suggest the direction for improvement of respirator filters of good quality in Korea. Two mechanical filters, S and K made in Korea, three filtering facepieces, S made in China, C made in Korea and M made in USA, which were widely used in the workplace, were selected and tested efficiency and pressure drop in accordance with flow rate, using with Automated Filter Tester Model 8110 (TSI, USA). The best quality factor within the same respirator filter categories was $0.0672cm^{-1}\;H_2O$ for mechanical filter S, $0.0698cm^{-1}\;H_2O$ for filtering facepiece M at flow rate of 32Lpm. Mechanical filter S would be the best suitable during heavy work since qulity factors decrease less sharply than any others as increased flow rates. It was necessary for mechanical filter S to lower pressure drop without increasing efficiency, but mechanical filter K should be increased efficiency and decreased pressure drop. While filtering facepiece M had the best quality performance of three ones, Sand C should get much higher efficiency and lower pressure for better performance.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.10
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• pp.1350-1353
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• 2004

To further investigate the regions on porcine chromosome 7 that are responsible for economically important traits, phenotypic data from a total of 287 F2 individuals were collected and analyzed from 1998 to 2000. All animals were genotyped for eight microsatellite loci spanning the length of chromosome 7. QTL analysis was performed using interval mapping under the line-cross model. A permutation test was used to establish significance levels associated with QTL effects. Observed QTL effects were (chromosomewide significance, position of maximum significance in centimorgans): Birth weight (<0.01, 3); Carcass length (<0.05, 80); Longissimus muscle area (<0.01, 69); Skin percentage (<0.01, 69); Bone percentage (<0.01, 74); Fat depths at shoulder (<0.05, 54);Mean fat depth (<0.05, 81); Moisture in m. Longissimus Dorsi (<0.05, 88). Additional evidence was also found which suggested QTL for dressing percentage and fat depths at buttock. This study offers confirmation of several QTL affecting growth and carcass traits on SSC7 and provides an important step in the search for the actual major genes involved in the traits of economic interest.

• Bulletin of the Korean Chemical Society
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• v.33 no.8
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• pp.2508-2512
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• 2012

Cold shock proteins (CSPs) are a family of proteins induced at low temperatures. CSPs bind to single-stranded nucleic acids through the ribonucleoprotein 1 and 2 (RNP 1 and 2) binding motifs. CSPs play an essential role in cold adaptation by regulating transcription and translation via molecular chaperones. The solution nuclear magnetic resonance (NMR) or X-ray crystal structures of several CSPs from various microorganisms have been determined, but structural characteristics of psychrophilic CSPs have not been studied. Therefore, we optimized the purification process to obtain highly pure Lm-Csp and determined the three-dimensional structure model of Lm-Csp by comparative homology modeling using MODELLER on the basis of the solution NMR structure of Bs-CspB. Lm-Csp consists of a ${\beta}$-barrel structure, which includes antiparallel ${\beta}$ strands (G4-N10, F15-I18, V26-H29, A46-D50, and P58-Q64). The template protein, Bs-CspB, shares a similar ${\beta}$ sheet structure and an identical chain fold to Lm-Csp. However, the sheets in Lm-Csp were much shorter than those of Bs-CspB. The Lm-Csp side chains, E2 and R20 form a salt bridge, thus, stabilizing the Lm-Csp structure. To evaluate the contribution of this ionic interaction as well as that of the hydrophobic patch on protein stability, we investigated the secondary structures of wild type and mutant protein (W8, F15, and R20) of Lm-Csp using circular dichroism (CD) spectroscopy. The results showed that solvent-exposed aromatic side chains as well as residues participating in ionic interactions are very important for structural stability. Further studies on the three-dimensional structure and dynamics of Lm-Csp using NMR spectroscopy are required.

• Bulletin of the Society of Naval Architects of Korea
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• v.26 no.2
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• pp.1-12
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• 1989

This paper presents a method of minimizing the wave resistance components, due to the linear wave propagating to the far field and the breaking wave in the vicinity of the hull. This method consists of the linear optimization method for the linear wave resistance and the statistical optimization method for the breaking wave resistance through the analysis of the experimental data. For the purpose of the application, a wall-sided model with parabolic waterplane shape was selected as a basic hull form, and two modified hull forms with varied $C_p-curve$ of the fore-body were derived from the linear wave optimization method and the empirical method. The correlation between the linear wave resistance and the breaking wave resistance according to the $C_p-curve$ variation of the fore-body was investigated through the experimental and analytical results for the three hull forms. The fore-body shape optimized by the present method shows the reduction of the wave resistance by 47% comparing to the basic hull form at the design speed($F_n=0.26$).

• Journal of the Korean Institute of Intelligent Systems
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• v.14 no.7
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• pp.895-901
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• 2004

This paper describes a two-phase intelligent method for filtering spam mail based on textual information and hyperlinks. Scince the body of spam mail has little text information, it provides insufficient hints to distinguish spam mails from legitimate mails. To resolve this problem, we follows hyperlinks contained in the email body, fetches contents of a remote webpage, and extracts hints (i.e., features) from original email body and fetched webpages. We divided hints into two kinds of information: definite information (sender`s information and definite spam keyword lists) and less definite textual information (words or phrases, and particular features of email). In filtering spam mails, definite information is used first, and then less definite textual information is applied. In our experiment, the method of fetching web pages achieved an improvement of F-measure by 9.4% over the method of using on original email header and body only.