• 한국직업건강간호학회지
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• 제29권1호
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• pp.1-7
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• 2020

Purpose: The purpose of this study is to investigate the effect of work environment on health problems of nurses. Methods: The subjects of the study were 395 nurses who were wage workers among KWCS (Korean Working Conditions Survey) respondents in 2014. The work environments were measured by the KWCS questionnaire. Results: 48.5% of the 395 nurses had health problems. The prevalence of musculoskeletal diseases (34.7%) was the highest among all health problems. The ergonomic work environment was significantly related to musculoskeletal disorders, headache and eye strain, and fatigue. In addition, the increase in work-individual interface area was significantly related to fatigue. Conclusion: The work environment of nurses affects health problems. It is therefore important to develop strategies that improve the health problems of nurses by reducing ergonomic and psycho-social risk factors.

• 한국의류산업학회지
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• 제3권4호
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• pp.357-361
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• 2001

This paper is concern with the effect of various conditions on mechanical properties of textile fabrics by water soluble resin treatment. Resin treatment of cotton, acetate, viscose rayon, polyester, nylon and acryl fabrics were made by aqueous resin treatment to improve the mechanical properties. The mechanical properties of fabrics, the breaking strength and strain were measured and surface reflectance was measured by color eye. The breaking strength and surface reflectance of fabrics by water soluble resin treatment showed difference by the different treatment concentration. The surface reflectance was increased by water soluble resin treatment. The breaking strength was lower in fabrics with resin treatment than fabrics with none treatment.

• Journal of Microbiology and Biotechnology
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• 제15권4호
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• pp.866-872
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• 2005

H. pylori is known to cause severe gastric diseases, including peptic ulcers and gastric cancers, and a link has also been suggested with iron-deficiency anemia (IDA). However, little is known about the pathogenesis of H. pylori-associated IDA. In the present study, to determine whether H. pylori strains are correlated with the prevalence of IDA, we analyzed and compared the sequences of the napA genes encoding a bacterioferritin-like protein in H. pylori strains. A total of 20 H. pylori strains were isolated from antral biopsies of patients with and without IDA, and the napA genes amplified from the genomic DNA were sequenced. A comparison of the deduced amino acid sequences for NapA revealed two sites with major variations. At residue 70, five out of the 12 non-IDA strains ($41.7\%$) contained serine, while only one of the 8 IDA strains ($12.5\%$) contained serine, indicating a significantly higher frequency of serine in the non-IDA strains. In addition, the NapA proteins from all 17 Western strains available on Web sites were found to contain serine residues at this position. Meanwhile, the other major variation was located at residue 73, where all eight IDA strains ($100\%$) contained leucine, while this was only true for eight of the 12 non-IDA strains ($66.7\%$). Therefore, these results indicated that the strains within each group were more genetically related to each other than to strains in the other group. When the expression level of the napA genes in the H. pylori strains was measured using RT-PCR, no significant difference was observed between the two groups, suggesting a similar intensity for the inflammatory responses induced by the NapA protein among the strains. Consequently, when taken together, the present data suggest that the occurrence of H. pylori-associated IDA may be partly determined by the infecting H. pylori strain, and the non-IDA strains are more closely related to Western strains than the IDA strains.

• 한국수학교육학회지시리즈C:초등수학교육
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• 제22권1호
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• pp.1-12
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• 2019

본 연구는 수학 패턴의 유형에 따른 패턴 발견에 대한 일반학생과 수학영재학생의 주의집중과 주의전환을 알아 보았다. 이를 위해 초등학교 5학년 일반학생과 수학영재 학생의 문제해결과정 중의 시선움직임을 시선추적기를 이용하여 분석하였다. 그 결과 첫째, 두 집단 간 표현양식에 따른 주의집중은 유의한 차이가 없었으나 주의전환은 두 집단 모두 숫자 표현양식에서 더 많았다. 둘째, 두 집단간의 생성방식에 따른 주의집중은 유의한 차이가 없었다. 주의전환은 두 집단 모두 증가변형 생성방식에서 더 많았다. 셋째, 일반학생들은 두 속성 모두에서 인접하지 않은 항 간의 비교에 더 많이 집중했다. 일반학생과 다르게 수학영재학생은 기하적 속성에서 주의전환이 더 많았다. 다양한 유형의 수학 패턴을 효과적으로 지도하기 위해서 두 집단 간 주의집중과 주의전환의 차이를 고려해야 할 것이다.

• 한국안광학회지
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• 제18권4호
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• pp.473-479
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• 2013

목적: 스마트폰 시청과 알코올 섭취에 따른 눈의 변화와 상관관계를 알아보고자 하였다. 방법: 안질환, 정신질환, 전신질환 그리고 알코올 대사에 관련된 약물복용의 병력이 없는 평소 건전한 음주습관을 가진 대상자 31명(남 18명, 여 13명)을 굴절검사, 각막곡률반경, 안압측정, 각막두께를 측정하고 분석하였다. 결과: 스마트폰 시청에 따른 호흡 중 혈중 알코올의 농도 변화는 15분, 30분, 45분, 60분 그리고 회복기에서 유의하게 감소하였다(p<0.01, p<0.001). 알코올 섭취 후 스마트폰 시청 전과 시청 후, 굴절검사 비교 결과 원주굴절력과 축에서 유의한 변화가 있었다(p=0.005, p=0.001). 알코올 섭취 후 스마트폰 시청에 따른 안압의 변화는 30분부터 유의하게 감소하였으며(p<0.001), 알코올을 섭취 한 상태에서 경과시간에 따른 스마트폰 시청은 각막두께에 유의한 변화를 주지 않았다. 결론: 스마트폰 시청과 알코올 섭취는 원주굴절력과 축 그리고 안압에 유의한 변화를 보인다. 시기능 피로를 초래할 수 있는 스마트폰 시청 및 알코올 섭취는 굴절검사 전 반드시 고려해야 할 요인이다.

• 한국안광학회지
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• 제17권3호
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• pp.285-291
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• 2012

목적: VDT 작업이 조절기능에 주는 영향을 알아보고자 하였다. 방법: 조절기능 이상과 전신 및 안질환이 없고 교정수술을 받은 경험이 없는 대학생 48명(남 16명, 여 32명)을 대상으로 VDT 작업 전과 2시간 작업 후의 굴절력, 조절래그, 조절용이성, 상대조절력과 최대조절력, 순목 횟수 값을 측정하였다. 원거리 굴절교정 도수를 착용한 상태에서 모든 검사를 실시하였고 VDT 증후군의 자각증상에 관련된 항목에 대해 설문조사를 실시하였다. 결과: 2시간동안 VDT 작업 후의 굴절력변화는 0.23 D 증가하였고, 조절래그 변화량은 우안에서는 $0.17{\pm}0.42D$, 좌안에서는 $0.23{\pm}0.47D$(t=2.26, p=0.03) 만큼 증가하였고 통계적으로 유의한 차이를 나타내었다. 조절용이성과 상대조절력과 조절력은 VDT 작업 후에 모두 감소하는 경향을 보였으나, 순목 횟수는 증가하는 양상을 보였다. VDT 작업 후 안정피로가 33.4%, 어깨통증이 33.3%의 자각증상을 보였다. 결론: 2시간 VDT 작업 시간에 따라 조절래그는 증가하였고, 전반적인 조절기능의 능력이 감소하는 경향을 보였으며, 시각적 부담을 주는 증상으로는 안정피로가 가장 높은 자각도를 보였다.

• 대한수의학회지
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• 제40권1호
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• pp.110-116
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• 2000

Duck viral hepatitis is an acutic, highly infectious viral disease of young ducklings. The most practical means for controlling duck viral hepatitis is the vaccination of ducklings or of a breeding stock. We attempted to develop a vaccine strain of duck hepatitis virus (DHV) using a Korean isolate by serial chicken embryo passages. The propagation of DHV in chicken embryos was carried 140 passages. After the $50^{th}$ passage, of which the virus was non-pathogenic for ducklings, approximately every $20^{th}$ passage of the virus was tested for vaccinal efficacy. Both the $70^{th}$ and $90^{th}$ passage of the virus gave good protection against challenge infection to a DHV-DRL reference strain(type 1) and a virulent Korean isolate. The $110^{th}$, $125^{th}$ and $140^{th}$ passage of the virus were less protective than the $70^{th}$ and $90^{th}$ passage, which means that more than $110^{th}$ passage may lead to over-attenuation of the virus. Ducklings vaccinated with the chicken-embryo-adapted virus by oral, intramuscular or eye drop administration showed earlier resistance to challenge infection from 3 to 7 days postvaccination. Of the above methods, ducklings vaccinated intramuscularly presented the most rapid resistance against challenge. The minimum immune dose of the chicken-embryo-adapted virus in ducklings was also studied. Ducklings inoculated with a dose of $10^{2.0}\;ELD_{50}$ and below were not fully protected against challenge with a virulent DHV, showing a protection rate of 67% to 73%, but ducklings inoculated with a dose of $10^{3.0}\;ELD_{50}$ and over were completely protected. The virus yield of the chicken-embryo-adapted DHV was examined at 24hrs and 48hrs of the incubation time in the allantoic fluid, embryo head and embryo minus head of the embryonating egg. In all three components, the titer of the virus was higher at 48 hours than that at 24 hours after incubation. And the titer of the virus was higher in the embryo minus head, embryo head and the allantoic fluid, in order. Field trials for evaluating the efficacy of the attenuated DHV as a live vaccine were done in duck farms with about 25% mortality of flocks resulting from duck viral hepatitis. After the use of the experimental vaccine, the mortality due to duck viral hepatitis was dramatically reduced in the farms. These results indicated that the attenuated DHV using a Korean isolate could be a good candidate as a live vaccine strain of DHV in Korea.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2018년도 추계학술대회
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• pp.113-113
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• 2018

Endophthalmitis is a disease that causes ocular inflammation and has a catastrophic effect on eyesight. Recent studies show that Enterococcus faecalis is rapidly increasing causative bacterium of endophthalmitis. It is predicted that the increased endophthalmitis by E. faecalis is presumable due to the high resistance of E. faecalis to moxifloxacin (MFX), which is a common antibiotic used for eye drop. Because of the need for therapeutic agents to overcome this problem, this study sought to explore the feasibility of developing a combination therapy using Orostachys japonicus. The ethylacetate fraction of O. japonicus (OJA) used in this study. Antimicrobial activity was tested 13 E. faecalis strains including one E. faecalis standard strain, eight clinically isolated E. faecalis strains and four quinolone resistant E. faecalis strains using CLSI antibiotic susceptibility test method. Minimal Inhibitory Concentration (MIC) of OJA was confirmed to be $500{\mu}g/ml$ for all 13 strains. Then we tested for the synergistic effect of OJA to MFX using checkboard test method. The MIC of MFX was $0.25{\mu}g/ml$ for the standard strain and 8 for the clinical isolates, and $16{\sim}64{\mu}g/ml$ for the quinolone - resistant strains. When OJA was mixed with MFX, no synergistic effect was observed in all strains, but the antibacterial activity of OJA remained unchanged. Most ocular other strains can be removed by MFX except the MFX resistant E. faecalis, which can be removed by OJA in combination therapy. Therefore, OJA can be a potential candidate for the combined treatment endophthalmitis.

• Parasites, Hosts and Diseases
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• 제46권3호
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• pp.157-164
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• 2008

Three Acanthamoeba isolates (KA/E9, KA/E17, and KA/E23) from patients with keratitis were identified as Acanthamoeba triangularis by analysis of their molecular characteristics, a species not previously recognized to be a corneal pathogen. Epidemiologic significance of A. triangularis as a keratopathogen in Korea has been discussed. Morphologic features of Acanthamoeba cysts were examined under a microscope with differential interference contrast (DIC) optics. Mitochondrial DNA (mtDNA) of the ocular isolates KA/E9, KA/E17, and KA/E23 were digested with restriction enzymes, and the restriction patterns were compared with those of reference strains. Complete nuclear 188 and mitochondrial (mt) 16S rDNA sequences were subjected to phylogenetic analysis and species identification. mtDNA RFLP of 3 isolates showed very similar patterns to those of SH621, the type strain of A. triangularis. 16S and 18S rDNA sequence analysis confirmed 3 isolates to be A. triangularis. 18S rDNA sequence differences of the isolates were 1.3% to 1.6% and those of 16S rDNA, 0.4% to 0.9% from A. triangularis SH621. To the best of our knowledge, this is the first report, confirmed by 18S and 16S rDNA sequence analysis, of keratitis caused by A. triangularis of which the type strain was isolated from human feces. Six isolates of A. triangularis had been reported from contaminated contact lens cases in southeastern Korea.

• 한국의상디자인학회지
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• 제6권2호
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• pp.15-20
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• 2004

These days are referred to as 'the times of textile fashion,' owing to the emphasis on textile design in the fashion industry. Accordingly, apparel companies have increased their interests in developing new types of textiles to overcome the limits of style and silhouette. Now the ultra-fashion of textile, a new way of process and design development, is given much more attention. A Moire interference pattern has a longer wavy circle of interference, an effect of intensity interference, than one made by piling more than one reflecting plate or transmitting plate. Till now, Moire interference patterns have been used to confirm scientific theory and to measure the structure of a body or a subject in areas such as physics and medical science. Work has also been done on the Moire interference effects on TV screens said to cause dizziness and eye strain. This study focuses on the new types of textiles by creating the appearance of the Moire phenomena. Contrary to the present usual stationary patterns of textiles, it is a varying pattern according to the different gratings, different angles, piling gratings, and the movements of the human bodies. In the preceding study, we observed Moire fringes formed by overlapping two different or same kinds of gratings such as parallel line gratings, square gratings, conic gratings and semicircular gratings and tried to find a promising possibility of new textiles through the method of clothes design simulation.