Sequencing and Comparative Analysis of napA Genes from Helicobacter pylori Strains Associated with Iron-Deficiency Anemia
![]() |
Hong, Myung-Hee
(Department of Bioscience & Biotechnology, Sejong University)
Choe, Yon-Ho (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University) Cho, Yang-Je (EyeGene Inc.) Ahn, Bo-Young (EyeGene Inc.) Lee, Na-Gyong (Department of Bioscience & Biotechnology, Sejong University) |
1 | Choe, Y. H., P. S. Kim, D. H. Lee, H. K. Kim, Y. S. Kim, Y. W. Shin, T. S. Hwang, H. J. Kim, S. U. Song, and M. S. Choi. 2002. Diverse vacA allelic types of Helicobacter pylori in Korea and clinical correlation. Yonsei Med. J. 43: 351-356 DOI |
2 | Cooksley, C., P. J. Jenks, A. Green, A. Cockayne, R. P. Logan, and K. R. Hardie. 2003. NapA protects Helicobacter pylori from oxidative stress damage, and its production is influenced by the ferric uptake regulator. Med. Microbiol. 52: 461-469 DOI ScienceOn |
3 | Corpet, F. 1988. Multiple sequence alignment with hierarchical clustering. Nucl. Acids Res. 16: 10881-10890 DOI PUBMED ScienceOn |
4 | Evans, D. J. Jr., D. G. Evans, T. Takemura, H. Nakano, H. C. Lampert, D. Y. Graham, D. N. Granger, and P. R. Kvietys. 1995. Characterization of a Helicobacter pylori neutrophilactivating protein. Infect. Immun. 63: 2213-2220 |
5 | Kawata, H., A. Ito, K. Kodama, S. Honda, T. Fujioka, and M. Nasu. 1996. Association between napA genotypes of Helicobacter pylori and severity of gastritis. Gastroenterol. 110 (suppl. 1): A152 |
6 | Milman, N., S. Rosenstock, L. Andersen, J. Jorgensen, and O. Bonnevie. 1998. Serum ferritin, hemoglobin, and Helicobacter pylori infection: A seroepidemiologic survey comprising 2794 Danish adults. Gastroenterology 115: 268-274 DOI ScienceOn |
7 | Tonello, F., W. G. Dundon, B. Satin, M. Molinari, G. Tognon, G. Grandi, G. Del Giudice, R. Rappuoli, and C. Montecucco. 1999. The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure. Mol. Microbiol. 34: 238-246 DOI ScienceOn |
8 | Atherton, J. C., P. Cao, R. M. Peek, M. K. Tummuru, M. J. Blaser, and T. L. Cover. 1995. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: Association of specific vacA types with cytotoxin production and peptic ulceration. J. Biol. Chem. 270: 17771-17777 DOI |
9 | Choe, Y. H., Y. J. Oh, N. G. Lee, I. Imoto, Y. Adachi, N. Toyoda, and E. C. Gabazza. 2003. Lactoferrin sequestration and its contribution to iron-deficiency anemia in Helicobacter pylori-infected gastric mucosa. J. Gastroenterol. Hepatol. 18: 980-985 DOI ScienceOn |
10 | Annibale, B., M. Marignani, B. Monarca, G. Antonelli, A. Marcheggiano, G. Martino, F. Mandelli, R. Caprilli, and G. Delle Fave. 1999. Reversal of iron deficiency anemia after Helicobacter pylori eradication in patients with asymptomatic gastritis. Ann. Intern. Med. 131: 668-672 |
11 | Dunn, B. E., H. Cohen, and M. J. Blaser. 1997. Helicobacter pylori. Clin. Microbiol. Rev. 10: 720- 741 |
12 | Looker, A. C., P. R. Dallman, M. D. Carroll, E. W. Gunter, and C. L. Johnson. 1997. Prevalence of iron deficiency in the United States. JAMA 277: 973-976 DOI ScienceOn |
13 | Montemurro, P., H. Nishioka, W. G Dundon, M. de Bernard, G Del Giudice, R. Rappuo]j, and C. Montecucco. 2002. The neutrophil-activating protein (RP-NAP) of Helicobacter pylori is a potent stimulant of mast cells. Eur. J. Immunol. 32: 671-676 DOI ScienceOn |
14 | Peek, R. M., S. A. Thompson, J. P. Donahue, K. T. Tham, J. C. Atherton, M. J. Blaser, and G G Miller. 1998. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc. Assoc. Am. Physicians 110: 531-544 |
15 | Choe, Y. H., J. E. Lee, and S. K. Kim. 2000. Effect of Helicobacter pylori eradication on sideropenic refractory anaemia in adolescent girls with Helicobacter pylori infection. Acta Paediatr. 89: 154-157 DOI ScienceOn |
16 | Satin, B., G. Del Giudice, V. Della Bianca, S. Dusi, C. Laudanna, F. Tonello, D. Kelleher, R. Rappuoli, C. Montecucco, and F. Rossi. 2000. The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a protective antigen and a major virulence factor. J. Exp. Med. 91: 1467-1476 |
17 | Choe, Y. H., S. K. Kim, B. K. Son, D. H. Lee, Y. C. Hong, and S. H. Pai. 1999. Randomized placebo-controlled trial of Helicobacter pylori eradication for iron-deficiency anemia in preadolescent children and adolescents. Helicobacter 4: 135-139 DOI ScienceOn |
18 | Miehlke, S., C. Kirsch, K. Agha-Amiri, J. Gunther, N. Lehn, P. Malfertheiner, M. Stolte, G Ehninger, and E. Bayerdorffer. 2000. The Helicobacter pylori vacA s1, m1 genotype and cagA is associated with gastric carcinoma in Germany. Int. J. Cancer 87: 322-327 DOI ScienceOn |
19 | Barabino, A. 2002. Helicobacter pylori-related iron deficiency anemia: A review. Helicobacter 7: 71-75 DOI PUBMED ScienceOn |
20 | Husson, M. O., D. Legrand, G. Spik, and H. Leclerc. 1993. Iron acquisition by Helicobacter pylori: Importance of human lactoferrin. Infect. Immun. 61: 2694-2697 |
21 | Zanotti, G., E. Papinutto, W. Dundon, R. Battistutta, M. Seveso, G. Giudice, R. Rappuoli, and C. Montecucco. 2002. Structure of the neutrophil-activating protein from Helicobacter pylori.J. Mol. Biol. 323: 125-130 DOI ScienceOn |
22 | Leakey, A., J. La Brooy, and R. Hirst. 2000. The ability of Helicobacter pylori to activate neutrophils is determined by factors other than H pylori neutrophils-activating protein. J. Infect. Dis. 182: 1749-1755 DOI ScienceOn |
![]() |