• 제목/요약/키워드: Extraction Process

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파삼의 항암활성 증진이 가능한 고압 추출 공정 (High Pressure Extraction Process of Low Quality Fresh Ginseng for Enhancing Anticancer Activities)

  • 하지혜;김영;김승섭;정명훈;정헌상;정재헌;유광원;이현용
    • 한국약용작물학회지
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    • 제17권6호
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    • pp.397-406
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    • 2009
  • The low quality fresh ginseng was extracted by water at $80^{\circ}C$ and 240 bar for 20 min (HPE, High pressure extraction process). The cytotoxicity on human normal kidney cell (HEK293) and human normal lung cell (HEL299) of the extracts from HPE showed 28.43% and 21.78% lower than that from conventional water extraction at $100^{\circ}C$ in adding the maximum concentration of $1.0\;mg/m{\ell}$. The human breast carcinoma cell and lung adenocarcinoma cell growth were inhibited up to about 86%, in adding $1.0\;mg/m{\ell}$ of extracts from HPE. This values were 9-12% higher than those from conventional water extraction. On in vivo experiment using ICR mice, the variation of body weight of mice group treated fresh ginseng extracts from HPE of 100 mg/kg/day concentration was very lower than control and other group. The extracts from HPE was showed longer survival times as 35.65% than that of the control group, and showed the highest tumor inhibition activities compared with other group, which were 70.64% on Sarcoma-180 solid tumor cells. On the high performance liquid chromatogram (HPLC), amount of ginsenoside-$Rg_2$, $Rg_3$, $Rh_1$ and $Rh_2$ on fresh ginseng were increased up to 43-183% by HPE, compared with conventional water extracts. These data indicate that HPE definitely plays an important role in effectively extracting ginsenoside, which could result in improving anticancer activities. It can be concluded that low quality fresh ginseng associated with this process has more biologically compound and better anticancer activities than that from normal extraction process.

Silicon wafer 에칭공정시 발생(發生)되는 폐(廢)에칭액 으로부터 초산(醋酸), 질산(窒酸) 및 불산(弗酸)의 분리.회수(分離.回收)에 관한 연구(硏究) (A study on the Separation of Acetic Acid, Nitric Acid and Hydrofluoric Acid from Waste Etching Solution of Si Wafer Manufacturing Process)

  • ;;;;;안재우
    • 자원리싸이클링
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    • 제16권1호
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    • pp.59-67
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    • 2007
  • 실리콘 웨이퍼 제조공정 중 발생되는 초산, 질산 및 불산을 함유한 3성분계 폐혼산으로부터 개별산으로 분리하여 재활용할 목적으로 용매추출법을 적용하였다. 각 산의 분리를 위해 사용한 추출제로는 초산의 경우는 EHA(2-Ethylhexlalcohol)를 사용하였고, 질산과 불산의 경우에는 TBP(Tri-butylphosphate)를 사용하여 각 산의 분리과정에 대한 공정설계를 위한 기초 data를 얻고자 하였다. 3성분계 폐혼산에서 초산을 추출 분리하고 이후 추출여액 중 질산 및 불산을 순차적으로 추출 분리 할 수 있는 연속공정개발을 위하여 기초 실험 자료와 McCabe-Thiele해석을 통해 최적 투입유량비(O/A), 소요단수(Stage) 등을 결정하였다. 분석 결과 혼산으로부터 초산의 회수율은 90%이상 이었으며 초산 추출여액에서 질산의 회수율은 90%, 최종 추출잔류액에서 불산의 회수율은 67%이상 이었다.

탄산화 공정 적용을 위한 시멘트 산업부산물 내 양이온 추출 및 분리 연구 (A Study on the Cation Extraction and Separation in Cement Industrial By-products for Applications to the Carbonation Process)

  • 이예환;한동희;이상문;엄한기;김성수
    • 공업화학
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    • 제30권1호
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    • pp.34-38
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    • 2019
  • 탄산화 공정을 위한 Ca 추출원으로 시멘트 산업부산물을 사용하였다. ICP와 XRD 분석을 통하여 시멘트 산업부산물은 대부분 CaO와 KCl로 구성되어 있음을 확인하였다. 최적화된 추출용제의 종류 및 농도는 1.5 M of hydrochloric acid이며 최적의 고액비는 0.1 g/mL이었다. 추출 성능 실험 결과를 통해 양이온의 추출효율은 이온 결합 형태 및 용해도에 의존함으로 판단되었다. 또한 추출 공정 후, 첨가물의 종류 및 주입 순서에 따라 선택적으로 양이온이 분리될 수 있음을 확인하였다. pH를 9.5, 13으로 조절하기 위하여 NaOH를 주입하였을 때 불순물과 $Ca(OH)_2$가 침전되었으며, $C_2H_5OH$를 주입한 경우 KCl 형태로 분리된 K가 침전되었다.

복합 고온 전처리 더덕 추출물의 미백 활성 탐색 (Screening of Skin Whitening Activity of Codonopsis lanceolata Extract by Complex Steaming Process)

  • 김지선;김지웅;권희석;임혜원;이현용
    • 한국약용작물학회지
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    • 제21권1호
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    • pp.54-60
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    • 2013
  • According to previous reports, antioxidant activities of Codonopsis lanceolata could be increased by a steaming process. This study was performed to improve its antioxidant activity and skin whitening activities of C. lanceolata by high pressure and stepwise steaming complex process. The complex processed C. lanceolata showed highest free radical scavenging acitivity as 45.21%, and for phenol and flavonoid contents, complex processed C. lanceolata contained higher than those from conventional extraction process or steaming process alone. The Cytotoxicity of all C. lanceolata extracts also showed low cytotoxicity against human fibroblast cell (CCD-986sk) as 4.49 ~ 10.40%. In whitening activity, high inhibition of tyrosinase activity was estimated as 25.08% by adding the extracts from complex process. We found that whitening and antioxidant activity of complex processed C. lancolata extract was higher than those obtained from conventional extraction and a steaming process because various kinds of antioxidant compounds could be easily released by combined process, compared to one of each process.

HBT를 위한 간단한 DC CAD 모델과 파라메터 추출 방법 (Simple DC CAD model and parameter extraction method for HBT)

  • 서영석;박용완
    • 전자공학회논문지D
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    • 제35D권7호
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    • pp.48-55
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    • 1998
  • We propose a new static current source model and parameter extraction method for AlGaAs/GaAs HBT. The proposed model has 9 parameters describing internal currents and are experessed with the physically meaningful parameters.The proposed parameter extraction method uses the measured dC IV curves and does not need the gummel plt data and any optimization process. the constructed model based on the proposed method predicts the measured data well.

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마이크로파를 이용한 잔류 살충제 Imidacloprid 분석용 시료전처리 기술개발 (Development of the Sample Pretreatment Technique using Microwave for Analysis of Insecticide Imidacloprid Residues)

  • 안순용;조한근;이은영
    • Journal of Biosystems Engineering
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    • 제32권2호
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    • pp.121-129
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    • 2007
  • This study was conducted to elucidate extraction efficiency by microwave technique in comparison with sonication technique for extraction of insecticide residue in pear. In the analysis of the extraction efficiency of microwave for a pear spiked with imidacloprid, the extraction efficiency by microwave power of 300 W with extraction temperature of $80^{\circ}C$, heating time of 1 to 3 minute was shown to be similar with the extraction time 20 minutes by sonication. The optimal condition. in consideration of economical condition and treatment time, for microwave extraction of imidacloprid in the pear were 300 watts of power supply, $100^{\circ}C$ of extraction temperature, 1 minute of heating time and 10 mL of acetone volume. A new microwave vessel was developed to rapidly process the sample of the insecticide imidacloprid residues in the pear. This vessel was designed to include a reaction chamber and a filtration equipment, and a gathering chamber. The system could curtail a pretreatment time to 21 minutes than sonication and 7.9 minutes than the previous microwave vessel.

Optimization of Oil from Moringa oleifera seed using Soxhlet Extraction method

  • Ojewumi, M.E.;Oyekunle, D.T.;Emetere, M.E.;Olanipekun, O.O.
    • 식품보건융합연구
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    • 제5권5호
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    • pp.11-25
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    • 2019
  • Extraction of oil from Moringa oleifera seed using Response Surface Methodology (RSM) was investigated. Effects of three factors namely: sample mass, particle size and extraction time on the response, Moringa oleifera a volume extracted, were determined. The Box-Behnken design of RSM was employed which resulted in 15 experimental runs. Extraction was carried out in a 250 ml Soxhlet extractor with Hexane and Ethanol as solvent. The Moringa oleifera seed powder was packed inside a muslin cloth placed in a thimble of the Soxhlet extractor. The extraction was carried out at 60℃ using thermostatic heating mantle. The solvent in the extracted oil was evaporated and the resulting oil further dried to constant weight in the oven. This study demonstrates that Moringa oleifera oil can be extracted from its seed using ethanol and acetone as extraction solvent. The optimum process variables for both solvent (ethanol and acetone) was determined at sample weight of 40 g, particle size of 325 ㎛ and extraction time of 8 hours. It can be deduced that using acetone as solvent produces a higher yield of oil at the same optimum variable conditions compared to when ethanol was used.

다양한 용액으로부터 용매추출에 의한 금과 은의 분리 (Separation of Gold and Silver from Diverse Solutions by Solvent Extraction)

  • 행위동;이만승
    • 자원리싸이클링
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    • 제26권5호
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    • pp.3-11
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    • 2017
  • 금과 은은 귀금속으로 첨단소재를 제조하는데 사용된다. 용매추출은 다양한 침출용액으로 부터 순수한 금과 은을 회수할 수 있는 중요한 공정이다. 본 논문에서는 cyanide, thiocyanate, thiosulfate, thiourea과 염산용액에서 금(I, III)과 은(I)의 용액화학 및 용매추출에 의한 분리를 고찰했다. 여러 단독 및 혼합추출제에 의한 금(I, III)과 은(I)의 용매추출 및 분리거동을 각 침출용액에서 추출반응과 추출제의 선택도를 토대로 비교했다. 염산용액이 용매추출에 의한 금과 은의 분리의 효율측면에서 적당하다.

미세조류로부터 색소물질 생산 증대를 위한 추출 조건 최적화 (Optimization of Extraction Conditions to Enhance Production of Bioactive Compounds from Microalgae)

  • 강민호;박제훈;박하영;김소희;김진우
    • 한국수산과학회지
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    • 제56권1호
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    • pp.28-32
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    • 2023
  • We optimized ultrasound-assisted extraction to improve the extraction efficiency of bioactive compounds from the microalgae Acutodesmus reginae. To optimize this extraction process, we investigated the effects of solvent type, solvent concentration, extraction time, extraction number, and extraction power on the production of lutein, α-carotene, β-carotene, and chlorophylls a, and b. After sequential optimization of these main variables, the maximum amount of each compound was extracted at 30℃ with an ultrasound power of 80 W and using 99.5% methanol. Under these optimum conditions, the amount of lutein, α-carotene, β-carotene, and chlorophylls a, and b, were measured as 10.43, 8.66, 3.76, 15.43, and 6.39 mg/g dry matter respectively.

MEMS 부품을 위한 다결정 박막의 탄성 물성치 추출 시스템과 적용 (Elastic Property Extraction System of Polycrystalline Thin-Films for Micro-Electro-Mechanical System Device and Its Applications)

  • 정향남;최재환;정회택;이준기
    • 한국정밀공학회지
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    • 제22권12호
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    • pp.170-174
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    • 2005
  • A numerical system to extract effective elastic properties of polycrystalline thin-films for MEMS devices is developed. In this system, the statistical model based on lattice system is used for modeling the microstructure evolution simulation and the key kinetics parameters of given micrograph, grain distributions and deposition process can be extracted by inverse method proposed in the system. In this work, effects of kinetics parameters on the extraction of effective elastic properties of polycrystalline thin-films are studied by using statistical method. Effects of the fraction of the potential site($f_p$) among the parameters for deposition process of microstructure on the extraction of effective elastic properties of polycrystalline thin-films are investigated. For this research, polysilicon is applied to this system as the polycrystalline thin-films.