• Korean Journal of Radiology
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• v.22 no.3
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• pp.324-333
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• 2021

Objective: The clinical course of an individual patient with heart failure is unpredictable with left ventricle ejection fraction (LVEF) only. We aimed to evaluate the prognostic value of cardiac magnetic resonance (CMR)-derived myocardial fibrosis extent and to determine the cutoff value for event-free survival in patients with non-ischemic cardiomyopathy (NICM) who had severely reduced LVEF. Materials and Methods: Our prospective cohort study included 78 NICM patients with significantly reduced LV systolic function (LVEF < 35%). CMR images were analyzed for the presence and extent of late gadolinium enhancement (LGE). The primary outcome was major adverse cardiac events (MACEs), defined as a composite of cardiac death, heart transplantation, implantable cardioverter-defibrillator discharge for major arrhythmia, and hospitalization for congestive heart failure within 5 years after enrollment. Results: A total of 80.8% (n = 63) of enrolled patients had LGE, with the median LVEF of 25.4% (19.8-32.4%). The extent of myocardial scarring was significantly higher in patients who experienced MACE than in those without any cardiac events (22.0 [5.5-46.1] %LV vs. 6.7 [0-17.1] %LV, respectively, p = 0.008). During follow-up, 51.4% of patients with LGE ≥ 12.0 %LV experienced MACE, along with 20.9% of those with LGE ≤ 12.0 %LV (log-rank p = 0.001). According to multivariate analysis, LGE extent more than 12.0 %LV was independently associated with MACE (adjusted hazard ratio, 6.71; 95% confidence interval, 2.54-17.74; p < 0.001). Conclusion: In NICM patients with significantly reduced LV systolic function, the extent of LGE is a strong predictor for long-term adverse cardiac outcomes. Event-free survival was well discriminated with an LGE cutoff value of 12.0 %LV in these patients.

• Geomechanics and Engineering
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• v.12 no.6
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• pp.965-981
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• 2017

Stability of vertical escarpments has been the subject of discussion for long time. However, available literature provides scarce knowledge about the effect of the formation of undercut and surface cracks on the stability of a vertical escarpment. The present study deals with a systematic analysis of the effect of surface cracks and undercut on slope stability using finite element based lower bound limit analysis. In the present analysis, the non-dimensional stability factor (${\gamma}H/c$) is used to inspect the degrading effect of undercut and cracks developed at different offset distances from the edge of the vertical escarpment. Failure patterns are also studied in detail to understand the extent and the type of failure zone which may generate during the state of collapse.

• Transactions of Materials Processing
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• v.9 no.6
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• pp.663-669
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• 2000

A material model has been presented, at the continuum level, for the representation of superplastic deformation coupled with microstructural evolution. The model presented enables the effects of the spatial variation of distributions of grain size to be predicted at the process level. The model has been tested under conditions of both homogeneous and inhomogeneous stress and strain by carrying out detailed comparison of predicted distributions of grain size and their evolutions with experimentally obtained data. Experimental measurements have shown the extent of the spatial variation of the distribution of grain size that exists in the titanium alloy, Ti-6Al-4V. It is shown that whilst not large, the variations in grain size distributions are sufficient to lead to the development of inhomogeneous deformation in test pieces, which ultimately result in localisation of strain and failure.

• 제어로봇시스템학회:학술대회논문집
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• 1988.10b
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• pp.764-769
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• 1988

In this paper the failure possibility and the error possibility are used to represent reliability of a technical component and that of a human operator, respectively. The failure possibility and the error possibility are fuzzy sets on the interval [0,1]. In a man-machine system, reliability of the technical component and that of the human operator are usually affected by many factors, e.g., the environment in which a machine is operated, psychological stress of the human operator, etc. The possibility is derived from not only the failure or the error rate but also estimates of these factors. The fuzzy reasoning plays an important role in the derivation. The reliability analysis is performed by the use of the possibility obtained by the present method. Moreover this paper discusses the sensitivity analysis which evaluates what extent the change of the estimation of each factor has an influence on reliability of a man-machine system. The important factors to be ameliorated are shown through the sensitivity analysis.

• Interaction and multiscale mechanics
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• v.5 no.2
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• pp.157-168
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• 2012

The dilatancy of granular materials has significant influence on its mechanical behaviors. The dilation angle is taken as a constant in conventional associated or non-associated flow rules based on Drucker-Prager yields theory. However, various experimental results show the dilatancy changes during progressive failure of granular materials. A non-associated flow rule with evolution of dilation angle is adopted in this study, and Cosserat continuum theory is used to describe the behaviors of granular materials for considering to some extent the its internal structure. Numerical examples focus on the bearing capacity and localization of granular materials, and results illustrate the capability and performance of the presented model in modeling the effect on failure behavior of granular materials.

• Journal of the Korean GEO-environmental Society
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• v.23 no.1
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• pp.15-23
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• 2022

This paper presents the results of full-scale load tests performed frictional anchors to various lengths at several sites in Korea. Various rock types were tested, ranging from highly weathered shale to sound gneiss. In many tests, rock failure was reached and the ultimate loads were recorded along with observations of the shape and extent of the failure surface. Laboratory tests were also conducted to investigate the influence of the corrosion protection sheath on the bond strength. Based on test results, the main parameters governing the uplift capacity of the rock anchor system were determined. By evaluation of the ultimate uplift capacity of anchor foundations in a wide range of in situ rock masses, rock classification suitable for structural foundation was developed. Finally, a very simple and economical design procedure is proposed for rock anchor foundations subjected to uplift tensile loads.

• Korean Circulation Journal
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• v.53 no.5
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• pp.294-312
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• 2023

Heart failure (HF) is a global health problem closely related to morbidity and mortality. As the burden of HF increases, it is necessary to manage and treat this condition well. However, there are differences between real-world practice and guidelines for the optimal treatment for HF. Patient-related, healthcare provider-related, and health system-related factors contribute to poor adherence to optimal care. This review article aims to examine HF treatment patterns and treatment adherence in real-world practice, identify clinical gaps to suggest ways to improve the quality of care for HF and clinical outcomes for patients with HF. Although it is important to optimize treatment based on evidence-based guidelines to the greatest extent, it is known that there is still poor treatment adherence, and many patients do not receive guideline-directed medical therapy, especially at the early stages. To improve medication adherence, qualitative evaluation through performance measurement, as well as education of patients, caregivers and medical staff through a multidisciplinary approach are important.

• Journal of the Korean Operations Research and Management Science Society
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• v.29 no.4
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• pp.95-116
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• 2004

This study will attempt to build an integrated model of the customer satisfaction process with service encounter in a comprehensive point of view including the expectancy-disconfirmation theory, justice theory, and attribution theory. In addition, this study will attempt to examine the influence of service failure-related variables and service recovery-related variables on customer satisfaction in the airline firms' service failure and recovery situation. The results showed that the higher the controllability and severity of the failure, the more positive influence on expectancy of recovery and more negative influence on the recovery satisfaction increased. They also showed that the higher procedural recovery efforts and distributive/interactional recovery efforts, the more positive influence on perceived recovery performance and recovery satisfaction also increased. It was found that the recovery satisfaction with service encounter depended on the extent to which the customer's perception of recovery efforts confirmed the expectancy of recovery. Also it was found that perceived recovery performance has an effect on recovery satisfaction through the mediation of recovery disconfirmation indirectly as well as directly.

• Korean Journal of Radiology
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• v.22 no.1
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• pp.63-71
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• 2021

Objective: To identify the CT findings associated with treatment failure after antibiotic therapy for acute appendicitis. Materials and Methods: Altogether, 198 patients who received antibiotic therapy for appendicitis were identified by searching the hospital's surgery database. Selection criteria for antibiotic therapy were uncomplicated appendicitis with an appendiceal diameter equal to or less than 11 mm. The 86 patients included in the study were divided into a treatment success group and a treatment failure group. Treatment failure was defined as a resistance to antibiotic therapy or recurrent appendicitis during a 1-year follow-up period. Two radiologists independently evaluated the following CT findings: appendix-location, involved extent, maximal diameter, thickness, wall enhancement, focal wall defect, periappendiceal fat infiltration, and so on. For the quantitative analysis, two readers independently measured the CT values at the least attenuated wall of the appendix by drawing a round region of interest on the enhanced CT (HU_post) and non-enhanced CT (HU_pre). The degree of appendiceal wall enhancement (HU_sub) was calculated as the subtracted value between HU_post and HU_pre. A logistic regression analysis was used to identify the CT findings associated with treatment failure. Results: Sixty-four of 86 (74.4%) patients were successfully treated with antibiotic therapy, with treatment failure occurring in the remaining 22 (25.5%). The treatment failure group showed a higher frequency of hypoenhancement of the appendiceal wall than the success group (31.8% vs. 7.8%; p = 0.005). Upon quantitative analysis, both HU_post (46.7 ± 21.3 HU vs. 58.9 ± 22.0 HU; p = 0.027) and HU_sub (26.9 ± 17.3 HU vs. 35.4 ± 16.6 HU; p = 0.042) values were significantly lower in the treatment failure group than in the success group. Conclusion: Hypoenhancement of the appendiceal wall was significantly associated with treatment failure after antibiotic therapy for acute appendicitis.

• Geotechnical Engineering
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• v.8 no.3
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• pp.37-50
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• 1992

Liquefaction leads to severe damage to earth structures after an earthquake. In this study, shaking table tests were performed on model waterfront structures as a countermeasure against liquefaction. The waterfront structure was reinforced by a compacted Bone, which was investigated for its effectiveness in protecting the structure from excessive deformation induced by the lateral pressure of liquefied ground. Through the tests . on embankment, double sheet pile wall, and anchor sheet pile wall, good quantitative information on the behavior of flow failure and the extent of reinforcement was obtained. The extent of a compacted zone for the protection of the structure depends on the magnitude of the acceleration during the shaking. The measured deformation was represented in terms of the extent of the compacted zone and the magnitude of the input acceleration.