• Title/Summary/Keyword: Extension agent

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Pharmacological Functional Magnetic Resonance Imaging of Cloropidol on Motor Task (운동과제에 대한 클로피도그렐의 약리적 뇌자기공명영상)

  • Chang, Yong-Min
    • Investigative Magnetic Resonance Imaging
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    • v.16 no.2
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    • pp.136-141
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    • 2012
  • Purpose : To investigate the pharmacologic modulation of motor task-dependent physiologic responses by antiplatelet agent, clopidogrel, during hand motor tasks in healthy subjects. Materials and Methods: Ten healthy, right-handed subjects underwent three functional magnetic resonance (fMRI) sessions: one before drug administration, one after high dose drug administration and one after reaching drug steady state. For the motor task fMRI, finger flexion-extension movements were performed. Blood oxygenation level dependent (BOLD) contrast was collected for each subject using a 3.0 T VHi (GE Healthcare, Milwaukee, USA) scanner. $T2^*$-weighted echo planar imaging was used for fMRI acquisition. The fMRI data processing and statistical analyses were carried out using SPM2. Results: Second-level analysis revealed significant increases in the extent of activation in the contralateral motor cortex including primary motor area (M1) after drug administration. The number of activated voxels in motor cortex was 173 without drug administration and the number increased to 1049 for high dose condition and 673 for steady-state condition respectively. However, there was no significant difference in the magnitude of BOLD signal change in terms of peak T value. Conclusion: The current results suggest that cerebral motor activity can be modulated by clopidogrel in healthy subjects and that fMRI is highly senstive to evidence such changes.

A Study on the Improvement Strategy of Reuse and Recycling of Home Appliances Waste (폐가전제품의 재이용 및 재활용 활성화 방안에 관한 연구)

  • Park, Chan-Hyuk;Chung, Jae-Chun;Lee, Jae-Woong;Kim, Young-Jun;Choi, Suk-soon
    • Journal of the Korea Organic Resources Recycling Association
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    • v.11 no.2
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    • pp.74-85
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    • 2003
  • The purpose of this study is to investigate present situation of recovery and treatment of waste home appliances, and to supply basic data for active reuse and recycling of waste home appliances. Among waste home appliances, refrigerator comprise 30.7%, television 37.8%, washing machine 22.9% and air conditioner 0.3%. Local government collected 46.2% of waste home appliances, producer and agent collected 49.7%, recycling center 4.1%. Seventeen percentage of waste home appliances are reused, 65% are recycled, and 18% are landfilled or incinerated. To improve the recycling activity of waste of home appliances, it is important to establish private reuse and recycling organization. It is also necessary to improve waste deposit and refund system for efficient recycling by decent financial support. Extension of a term of usage is another method to minimize waste home appliances. Finally, intensive education for consumer is necessary for waste minimization. Some portion of recycling and treatment cost can be allocated to the local government and large private business can shred and recycle waste home appliances.

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Leaf Spot of Kalanchoe (Kalanchoe blossfeldiana) Caused by Stemphylium lycopersici (Stemphylium lycopersici에 의한 칼란코에 점무늬병)

  • Kwon, Jin-Hyeuk;Jeong, Byoung-Ryong;Yun, Jae-Gill;Lee, Sang-Woo
    • Research in Plant Disease
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    • v.13 no.2
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    • pp.122-125
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    • 2007
  • Leaf spot disease of Kalanchoe (Kalanchoe blossfeldiana) occurred at the farmer's vinly house in Gangseo-gu, Busan Metropolitan City, Korea, 2006. The diseased plants with typical symptom were collected and the casual agent were isolated. Its mycological characteristics and pathogenicity were examined. The results were as follows. The typical symptoms of the disease appeared as small brownish or dark brown spot on both sides of the leaves. The spots tended to develop from lower leaves. The spots gradually enlarged into conspicuous necrotic lesions 1-5 mm in diameter. Colonies of the causal fungus formed on potato dextrose agar were velvety, gray or grayish brown in color, Conidia were cylindrical or obclavate to oblong in shape, brown in color, $24{\sim}65\;{\times}\;12{\sim}23\;{\mu}m$ in size and had 1-4 transverse septa, The optimum temperature for growth of the fungus was about $25-30^{\circ}C$. Conidiophores were brown in color, $32{\sim}135\;{\times}\;4{\sim}8\;{\mu}m$ in size and had 1-7 transverse septa. The fungus was identified as Stemphylium lycopersici (Enjoji) Yamamoto based on its symptom and mycological characteristics. This is the first report of leaf spot of Kalanchoe caused by S. lycopersici in Korea.

Characteristics of Watermelon Mosaic Virus Transmission Occurring in Korean Ginseng (인삼에서 발생하는 수박모자이크바이러스의 감염 특성)

  • Choi, Seung-Kook;Cho, In-Sook;Chung, Bong-Nam;Kim, Mi-Kyeong;Jung, Won-Kwon;Choi, Gug-Seoun
    • Research in Plant Disease
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    • v.20 no.3
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    • pp.206-210
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    • 2014
  • Korean ginseng (Panax ginseng) is the most popular herb for medical purpose in Korea. Recently, viral diseases from Korean ginseng showing various degrees of severe mottling, variegation and mosaic symptoms have caused quantity losses of Korean ginseng in a large number of farms. Watermelon mosaic virus (named WMV-gin) was identified as a causal agent for the disease of Korean ginseng. Interestingly, WMV-gin failed to infect both Korean ginseng plant and susceptible host species including cucurbitaceous plants by mechanical inoculation. However, WMV-gin could successfully infect Korean ginseng by transmission of two aphid species (Myzus persicae and Aphis gossypii). It is likely that transmission of WMV-gin was done by both the aphid species during feeding behavior of the two aphid species on Korean ginseng, though the aphids dislike feeding in Korea ginseng. Similarly, a strain of WMV (WMV-wm) isolated from watermelon was transmitted successfully to Korean ginseng plant by the two aphid species, but not by mechanical inoculations. Transmission assays using M. persicae and A. gossypii clearly showed both WMV-gin and WMV-wm were not transmitted from infected Korean ginseng plant to cucurbit species that are good host species for WMV. These results suggest WMV disease occurring in Korean ginseng plant can be controlled by ecological approaches.

Policy Direction for Fire Products Life Expectancy Legislation (소방용품 내용연수 제도화 정책방안)

  • Baek, Chang Sun;Park, In-Seon
    • Fire Science and Engineering
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    • v.30 no.1
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    • pp.111-120
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    • 2016
  • This study is intended to provide legislative direction for fire products life expectancy. Domestic and international laws relating to fire products life expectancy have been reviewed, and the results of a Fire Safety Manager Consciousness (FSMC) survey were analyzed. The FSMC survey has been designed in order to assist with the establishment of appropriate fire safety policy. A questionnaire survey was conducted with 660 fire safety administrators from 17 municipal and provincial districts, with the intention of gaining expertise on the extension of life-span for 32 fire products. The survey also asked for candidates opinions on future policy direction. Based on the survey results and the review of policies within other nations, we have devised a set of policy issues with the intention of extending the life-span of fire-safety items. The survey result revealed that 79.3% of Fire Safety Managers (FSMs) concurred with the establishment of legislation regarding the maintenance and correct care of fire-safety products. Overall, over 30% of FSMs were in favor of regulations regarding Ddry chemical fire extinguishers (77.3%), fire detectors (44.6%), fire hoses (44.4%), gaseous agent fire extinguisher (40.6%), automatic descending life lines (36.2%), exit lights (35.9%), air respirators (35.9%), extinguishing systems for residential cooking facilities (33.9%), automatic spray-type extinguishing units (33.9%), emergency lights (31.2%), and gas leakage detectors (30.7%). Especially, among these, dry chemical fire extinguishers (60.0%), detectors (20.0%), and fire hose (18.8%) were identified as the fire products primarily in need of maintenance legislation. The general consensus is that fire products older than 10 years need to be replaced. Based on the survey results, there was general agreement that fire product life expectancy is in need of legislation. This study recommends the introduction of fire product life expectancy legislation in phases.

Enhanced Cross-Layering Mobile IPv6 Fast Handover over IEEE 802.16e Networks in Mobile Cloud Computing Environment (모바일 클라우드 컴퓨팅 환경에서 IEEE 802.16e 네트워크에서의 향상된 교차계층 Mobile IPv6 빠른 핸드오버 기법)

  • Lee, Kyu-Jin;Seo, Dae-Hee;Nah, Jae-Hoon;Mun, Young-Song
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.12
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    • pp.45-51
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    • 2010
  • The main issue in mobile cloud computing is how to support a seamless service to a mobile mode. Mobile IPv6 (MIPv6) is a mobility supporting protocol which is standardized by the Internet Engineering Task Force (IETF). Mobile IPv6 fast handovers (FMIPv6) is the extension of MIPv6 which is proposed to overcome shortcomings of MIPv6. Recently, fast handovers for Mobile IPv6 over IEEE 802.16e which is one of broadband wireless access systems has been proposed by the IETF. It was designed for supporting cross-layer fast handover. In this paper, we propose an enhanced cross-layering mobile IPv6 fast handover over IEEE 802.16e networks. In our scheme, a new access router generates a new address for the mobile node by using a layer 2 trigger. We utilize a layer 2 message which is sent from a new base station to the new access router in order to inform the new access router of information of the mobile node. A previous access router sends a binding update message to the mobile node's home agent when it acquires the new address of the mobile node. We evaluate the performance of the proposed scheme compared with the existing schemes in terms of the signaling cost and the handover latency. From the results, we observe that the proposed scheme can support fast handover effectively over IEEE 802.16e networks than existing schemes.

Evaluation of in-vitro Anti-thrombosis and Anti-oxidation Activity of Lees of Takju (Wookukseng) (우국생 탁주 주박의 항혈전 및 항산화 활성)

  • Kim, Mi-Sun;Lee, Ye-Seul;Kim, Jong Sik;Shin, Woo-Chang;Sohn, Ho-Yong
    • Journal of Life Science
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    • v.25 no.4
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    • pp.425-432
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    • 2015
  • This study was performed to develop high-value-added biomaterials for health and beauty products. Extracts of ethanol and hot water and their subsequent organic solvent fractions were prepared from Lees of Wookukseng (LW), a commercialized Korean traditional rice wine. We investigated their activities on blood coagulation, platelet aggregation, hemolysis against human red blood cells (hRBCs), and anti-oxidation. The water content, pH and brix of the LW were 80.3%, 3.94 and 13.0°, respectively. The yield of ethanol extraction (6.62%) was 3.15 times higher than that of hot-water extraction (2.1%), and the ethyacetate fraction (EAF) of ethanol extract showed the highest content of total polyphenol (128 mg/g) among the various fractions. In anticoagulation activity assay, the EAF of ethanol extract showed a 15-fold extension in TT, PT, and aPTT, indicating that the EAFs contain various inhibitory substances against thrombin, prothrombin and coagulation factors. In anti-platelet aggregation activity assay, the butanol fraction and water residue of ethanol extract showed significant inhibition activity. The activities were comparable to aspirin, a commercial anti-thrombosis agent. The above extracts and fractions did not show hemolysis activity against hRBC up to 5 mg/ml, and had radical scavenging activity against DPPH anion, ABTS cation and nitrite. Our results suggest that the active fractions prepared from LW, which has no specific usage until now, have a high potential as novel resources for anti-thrombosis agents.

Genetic Characteristics of Acidovorax citrulli Population Causing Bacterial Fruit Blotch against Cucurbits in Korea (국내 박과 작물에서 과실썩음병을 일으키는 Acidovorax citrulli 집단의 유전적 특성)

  • Song, Jeong Young;Park, Su Yeon;Seo, Mun Won;Nam, Myeong Hyeon;Lim, Hyoun Sub;Lee, Seong-Chan;Lee, Youn Su;Kim, Hong Gi
    • Research in Plant Disease
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    • v.21 no.2
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    • pp.82-88
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    • 2015
  • Acidovorax citrulli, the causal agent of bacterial fruit blotch, has caused an economically destructive damage in cucurbits cultivation fields worldwide. To consider more effective disease management, 33 A. citrulli isolates collected from various cucurbits in Korea were analysed by multi-locus phylogeny using five conserved loci(16S rRNA, adk, gltA, glyA, pilT). Two distinct groups (KCC1 and KCC2) in the population were identified on the base of group-specific genetic variation. Out of them, the predominant group was KCC2 and both groups included isolates from melon, cucumber and watermelon. Sixty-four percent of KCC1 isolates were recovered from non-watermelon hosts and seventy-two percent of KCC2 isolates from watermelon. This study presented that there was genetic differentiation among A. citrulli population in Korea. Also, these results will be applied as a very useful data in effective disease management.

Changes of Aroma Compounds during Kimchi Powder Production and Encapsulation Effect of β-Cyclodextrin (김치 감압건조 시 향기성분의 변화 및 β-cyclodextrin의 향기성분 포집효과)

  • Eom, Hyun-Ju;Yoo, Ki-Seon;Yim, Chang Youn;Joo, Seoungjo;Han, Jinhee;Jin, Qing;Yoon, Hyang-Sik;Han, Nam Soo
    • Food Engineering Progress
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    • v.13 no.3
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    • pp.190-194
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    • 2009
  • The aim of this study was to investigate the change of volatile aroma compounds in kimchi during fermentation, before and after drying process. Also, the encapsulation effect of cyclodextrin on volatiles during the drying process was examined. GC-MS was used for detection and identification of volatile compounds. During kimchi fermentation, in the early stage, dimethyl sulfide, carbon disulfide were detected as major compounds and after 7 days several sulfur compounds, dimethyl disulfide, methyl 2-propenyl disulfide, allyl methyl sulfide, and di-2-propenyl disulfide bacame the major volatiles. After vacuum-drying, the kimchi powder lost 11 compounds but still retained 13 volatiles of which major compounds were dimethyl sulfide, acetaldehyde and methanethiol. In order to keep volatiles in kimchi powder along with the drying process, 0.25-1.0% cyclodextrin was added in kimchi and dried-kimchi was prepared by using vacuum dryer. Cyclodextrin acted as an encapsulation agent for aroma compounds and it resulted in less loss of volatiles during drying process. Addition of cyclodextrin will permit industry-scale production of dried-kimchi powder with less loss of aroma compounds.

A Study on the Active Economic Activities by the Job Program to Overcome the Poverty of the Elderly in the Aged Society (고령사회 노인빈곤 극복의 일자리사업을 통한 적극적 경제활동 방안 고찰)

  • Kim, Young-Chul;Kim, Seo-Ho
    • Industry Promotion Research
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    • v.6 no.1
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    • pp.55-62
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    • 2021
  • This study regards the need for jobs to overcome the poverty of the elderly in an aged society, and as well as researches ways to participate in active economic activities in old age. The results of the study are as follows. First, the legal system needs to be improved. In addition to institutional support for the expansion of jobs for the elderly, improvement of awareness of the elderly and reinforcement of infrastructure such as a delivery system are required, and a legal basis for this is needed. To this end, occupations targeting the elderly must be selected first, and legal procedures must be prepared by the government. Second, there must be social consideration and support for the elderly. Extension of the retirement age plays an important role in enhancing employment for the elderly. Along with the improvement of the legal system, social consideration is required. Therefore, since the elderly policy without social consensus is bound to fail, various support methods that can lead to social support must be devised. Third, the elderly must have a sense of poverty and willingness to rehabilitate themselves. Elderly people should not only ask for their children and social support. The elderly must be able to find a way to become the economic agent themselves. To do this, a basic awareness of the elderly poverty consciousness is needed, and a change of awareness to escape the poverty of the elderly is necessary. Therefore, the elderly need to be self-reliant, and they must choose jobs according to their own abilities. In conclusion, the elderly job program is a part of income increase that solves the poverty of the elderly in the aged society, and the elderly are required to actively participate in economic activities.