• 제목/요약/키워드: Exploration and mining

검색결과 210건 처리시간 0.021초

Data Mining for High Dimensional Data in Drug Discovery and Development

  • Lee, Kwan R.;Park, Daniel C.;Lin, Xiwu;Eslava, Sergio
    • Genomics & Informatics
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    • 제1권2호
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    • pp.65-74
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    • 2003
  • Data mining differs primarily from traditional data analysis on an important dimension, namely the scale of the data. That is the reason why not only statistical but also computer science principles are needed to extract information from large data sets. In this paper we briefly review data mining, its characteristics, typical data mining algorithms, and potential and ongoing applications of data mining at biopharmaceutical industries. The distinguishing characteristics of data mining lie in its understandability, scalability, its problem driven nature, and its analysis of retrospective or observational data in contrast to experimentally designed data. At a high level one can identify three types of problems for which data mining is useful: description, prediction and search. Brief review of data mining algorithms include decision trees and rules, nonlinear classification methods, memory-based methods, model-based clustering, and graphical dependency models. Application areas covered are discovery compound libraries, clinical trial and disease management data, genomics and proteomics, structural databases for candidate drug compounds, and other applications of pharmaceutical relevance.

한국에서의 지구자기장관측의 현황 (THE STATUS QUO OF THE GEOMAGNETIC FIELD MEASUREMENTS IN KOREA)

  • 임무택;박영수;정현기;이희일
    • 천문학논총
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    • 제15권spc2호
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    • pp.15-20
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    • 2000
  • The geomagnetic measurements on the Korean Territory began in 1918 in the Incheon (Zinsen in Japanese pronunciation) Observatory of which the annual means of total magnetic field intensity, declination, and inclination still remain for 1918-1944. From 1970s, the National Geography Institute (NGI) and the Radio Research Laboratory (RRL) have tried independently to measure the geomagnetic field continuously. The RRL as the result of such efforts has installed 3 geomagnetic observatories, the first in Icheon and the second in Yongin in 1996, and the third in Jeju in 1997. From 1992, the Korea Institute of Geology, Mining and Materials (KIGAM) has tried also to measure the geomagnetism and as the result they have installed 2 geomagnetic observatories, one in Daejeon in 1998 and the other in Gyeongju in 2000. Nowadays, the RRL and the KIGAM collect the measured data into their own main computers by telecommunication in real time. The two institutions will cooperate in near future to link the two geomagnetic data bases so that the whole set of geomagnetic data measured on Korean Territory could be provided to the end users in Korea.

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Design Exploration of High-Lift Airfoil Using Kriging Model and Data Mining Technique

  • Kanazaki, Masahiro;Yamamoto, Kazuomi;Tanaka, Kentaro;Jeong, Shin-Kyu
    • International Journal of Aeronautical and Space Sciences
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    • 제8권2호
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    • pp.28-36
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    • 2007
  • A multi-objective design exploration for a three-element airfoil consisted of a slat, a main wing, and a flap was carried out. The lift curve improvement is important to design high-lift system, thus design has to be performed with considered multi-angle. The objective functions considered here are to maximize the lift coefficient at landing and near stall conditions simultaneously. Kriging surrogate model which was constructed based on several sample designs is introduced. The solution space was explored based on the maximization of Expected Improvement (EI) value corresponding to objective functions on the Krigingmodels. The improvement of the model and the exploration of the optimum can be advanced at the same time by maximizing EI value. In this study, a total of 90 sample points are evaluated using the Reynolds averaged Navier-Stokes simulation(RANS) for the construction of the Kriging model. In order to obtain the information of the design space, two data mining techniques are applied to design result. One is functional Analysis of Variance(ANOVA) which can show quantitative information and the other is Self-Organizing Map(SOM) which can show qualitative information.

지형을 포함한 MT 탐사 자료의 2차원 모델링과 역산 (Two-dimensional Modeling and Inversion of MT Data Including Topography)

  • 이성곤;송윤호;김정호;정승환
    • 지구물리와물리탐사
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    • 제5권4호
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    • pp.291-298
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    • 2002
  • 본 연구에서는 지형을 포함한 2차원 MT 역산 알고리듬을 개발하였다. 역산 과정시 필요한 모델 반응 계산을 위하여 유한요소법을 이용하였다. 공기와 지표면의 경계를 기준으로 고도에 따라 각 요소들의 절점을 수직으로 이동시킴으로써 추가적인 계산시간의 증가없이 간편히 지형을 구현하였다. 역산에서는 공간적인 함수로서 라그랑지 곱수를 결정하는 알고리듬을 채택하여 역산의 분해능과 안정성을 높이고자 하였다. 수치모델 실험을 통하여 TM과 TE모드 자료의 지형효과를 고찰하였고, 수치 자료의 역산을 통하여 지형을 포함한 역산의 타당성을 살펴보았다. 또한 현장 자료에 대하여 적용하여 본 연구에서 개발된 지형을 포함한 MT자료 역산 알고리듬의 적용성을 확인하였다.

2차원 전기비저항 탐사를 위한 변형된 전극배열법에 관한 연구 (A Study on the Modified Electrode Arrays in Two-Dimensional Resistivity Survey)

  • 김정호;이명종;송윤호;정승환
    • 지구물리와물리탐사
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    • 제4권3호
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    • pp.59-69
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    • 2001
  • 2차원 전기비저항 탐사에 일반적으로 사용되는 전극배열들의 단점을 보완하기 위해 단극과 쌍극자를 사용하는 기존의 전극배열로부터 5 종류의 변형된 전극배열법을 제안하였다. 변형된 단극 배열법은 원거리 접지전극이 필요한 단극 배열법의 비효율성을 보완하기 위한 전극배열법이다. 4 종류의 쌍극자를 이용하는 변형된 전극배열법은 쌍극자 또는 단극-쌍극자 배열이 갖는 문제점, 즉 낮은 측정값에 의한 낮은 신호대 잡음비를 개선하여 높은 측정값의 획득이 가능하도록 설계하였다. 수치 모델링과 2차원 역산을 이용한 수치 실험을 수행하였으며, 전기적 잡음에 의한 영향과 분해능에 대하여 고찰하여 본 논문에서 제안된 전극배열의 효용성을 입증하였다.

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Multi-Objective Design Exploration for Multidisciplinary Design Optimization Problems

  • Obayashi Shigeru;Jeong Shinkyu;Chiba Kazuhisa
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2005년도 추계 학술대회논문집
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    • pp.1-10
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    • 2005
  • A new approach, Multi-Objective Design Exploration (MODE), is presented to address Multidisciplinary Design Optimization (MDO) problems by CFD-CSD coupling. MODE reveals the structure of the design space from the trade-off information and visualizes it as a panorama for Decision Maker. The present form of MODE consists of Kriging Model, Adaptive Range Multi Objective Genetic Algorithms, Analysis of Variance and Self-Organizing Map. The main emphasis of this approach is visual data mining. An MDO system using high fidelity simulation codes, Navier-Stokes solver and NASTRAN, has been developed and applied to a regional-jet wing design. Because the optimization system becomes very computationally expensive, only brief exploration of the design space has been performed. However, data mining result demonstrates that design knowledge can produce a good design even from the brief design exploration.

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심해저 광물자원 개발제도의 운영결과 분석 및 향후전망 (Evaluation on the Outcome of International Deep Seabed Mining Regime and Its Prospect)

  • 이용희
    • Ocean and Polar Research
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    • 제27권1호
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    • pp.97-108
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    • 2005
  • The International Seabed Authority (ISA) formally came into existence upon the entry into force of the UNCLOS on 16 November 1994. By adopting the Implementing Agreement in 1994, UNCLOS has the universality as a Magna Carta of International Ocean Regime, and the Deep Seabed Mining Regime could be operated as a unique one for the benefit of mankind. During last 10 years, ISA established the institutional framework successfully and made substantial and tangible progress in formulating the rules, regulations and procedures for the prospecting and exploration for polymetally nodules. Furthermore, RPI's obligations had been carried out completely, and the 7 RPI made contract with ISA to become a contractor who has an at least 15 you exclusive right for exploration in their allocated site. However, due to the uncertainty of commercial mining, the number of representatives from developing countries has been getting looser and looser and ISA has a problem of quorum of the Assembly. Land-based producers took a very strong opposite position to the contractors to make their loss in the minimum level. For the next decade, it might be prospected that ISA will focus on monitoring the contractor's activities, making rules, regulations and procedures for exploration on cobalt rich crust, sulphide and methane hydrate and implementing environment studies.

물리검층에 의한 파쇄대 인식과 동적 지반정수의 산출 (Application of geophysical well logging to fracture identification and determination of in-situ dynamic elastic constants.)

  • 황세호;이상규
    • 한국지구물리탐사학회:학술대회논문집
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    • 한국지구물리탐사학회 1999년도 제2회 학술발표회
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    • pp.156-175
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    • 1999
  • 물리검층은 최근에 토목지반조사분야에 대한 활용성이 증가하고 있다. 이것은 물리 검층이 시추공 내에서 분해능 높은 다양한 원위치 물성정보를 제공할 수 있는 장점이 있기 때문이다. 현재 토목지반조사분야에서 적용되고 있는 것은 주로 암상구분, 파쇄대 인식과 동탄성계수의 산출, 지하수흐름검층 등이다. 이와 관련하여 최근에 활용성이 증가하는 물리검층법에 대한 소개와 지반조사와 관련한 물리검층 사례, 그리고 완전파형음파검층에 의한 탄성파 속도와 암반분류와 관계에 대한 사례를 소개한다.

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