• Genomics & Informatics
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• v.1 no.2
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• pp.65-74
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• 2003

Data mining differs primarily from traditional data analysis on an important dimension, namely the scale of the data. That is the reason why not only statistical but also computer science principles are needed to extract information from large data sets. In this paper we briefly review data mining, its characteristics, typical data mining algorithms, and potential and ongoing applications of data mining at biopharmaceutical industries. The distinguishing characteristics of data mining lie in its understandability, scalability, its problem driven nature, and its analysis of retrospective or observational data in contrast to experimentally designed data. At a high level one can identify three types of problems for which data mining is useful: description, prediction and search. Brief review of data mining algorithms include decision trees and rules, nonlinear classification methods, memory-based methods, model-based clustering, and graphical dependency models. Application areas covered are discovery compound libraries, clinical trial and disease management data, genomics and proteomics, structural databases for candidate drug compounds, and other applications of pharmaceutical relevance.

• Geophysics and Geophysical Exploration
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• v.5 no.1
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• pp.64-67
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• 2002

• Geophysics and Geophysical Exploration
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• v.13 no.1
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• pp.132-135
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• 2010

• Publications of The Korean Astronomical Society
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• v.15 no.spc2
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• pp.15-20
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• 2000

The geomagnetic measurements on the Korean Territory began in 1918 in the Incheon (Zinsen in Japanese pronunciation) Observatory of which the annual means of total magnetic field intensity, declination, and inclination still remain for 1918-1944. From 1970s, the National Geography Institute (NGI) and the Radio Research Laboratory (RRL) have tried independently to measure the geomagnetic field continuously. The RRL as the result of such efforts has installed 3 geomagnetic observatories, the first in Icheon and the second in Yongin in 1996, and the third in Jeju in 1997. From 1992, the Korea Institute of Geology, Mining and Materials (KIGAM) has tried also to measure the geomagnetism and as the result they have installed 2 geomagnetic observatories, one in Daejeon in 1998 and the other in Gyeongju in 2000. Nowadays, the RRL and the KIGAM collect the measured data into their own main computers by telecommunication in real time. The two institutions will cooperate in near future to link the two geomagnetic data bases so that the whole set of geomagnetic data measured on Korean Territory could be provided to the end users in Korea.

• International Journal of Aeronautical and Space Sciences
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• v.8 no.2
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• pp.28-36
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• 2007

A multi-objective design exploration for a three-element airfoil consisted of a slat, a main wing, and a flap was carried out. The lift curve improvement is important to design high-lift system, thus design has to be performed with considered multi-angle. The objective functions considered here are to maximize the lift coefficient at landing and near stall conditions simultaneously. Kriging surrogate model which was constructed based on several sample designs is introduced. The solution space was explored based on the maximization of Expected Improvement (EI) value corresponding to objective functions on the Krigingmodels. The improvement of the model and the exploration of the optimum can be advanced at the same time by maximizing EI value. In this study, a total of 90 sample points are evaluated using the Reynolds averaged Navier-Stokes simulation(RANS) for the construction of the Kriging model. In order to obtain the information of the design space, two data mining techniques are applied to design result. One is functional Analysis of Variance(ANOVA) which can show quantitative information and the other is Self-Organizing Map(SOM) which can show qualitative information.

• Geophysics and Geophysical Exploration
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• v.5 no.4
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• pp.291-298
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• 2002

We have developed a two-dimensional (2-D) magnetotelluric (MT) inversion algorithm, which can include topographic effects in inversion. We use the finite element method (FEM) to incorporate topography into forward calculation. Topography is implemented simply by moving nodes of rectangular elements in z-direction according to the elevation of air-earth interface. In the inversion process, we adopt a spatially variable Lagrangian multiplier algorithm in the smoothness-constrained least-squares inversion. The inversion algorithm developed in this study reconstructs subsurface resistivity structure quite well when topography variation exists. Also, it turns out to be effective in both resolution and stability from a model study and field data application.

• Geophysics and Geophysical Exploration
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• v.4 no.3
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• pp.59-69
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• 2001

Five kinds of modified electrode arrays were proposed to overcome the weak points of the commonly used arrays using dipole and/or pole in two-dimensional resistivity surveys. The modified pole-pole array was suggested to overcome the inefficiency caused by distant earthing in pole-pole array. Four kinds of modified arrays using dipole were designed to enhance the signal-to-noise ratio of the conventional dipole-dipole and pole-dipole arrays through boosting up the measured potential difference. In the numerical experiments using the two-dimensional modeling and inversion, the effects of the ambient electrical noise and the resolving power were examined and the results showed the validity of the modified arrays proposed in this study.

• 한국전산유체공학회:학술대회논문집
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• 2005.10a
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• pp.1-10
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• 2005

A new approach, Multi-Objective Design Exploration (MODE), is presented to address Multidisciplinary Design Optimization (MDO) problems by CFD-CSD coupling. MODE reveals the structure of the design space from the trade-off information and visualizes it as a panorama for Decision Maker. The present form of MODE consists of Kriging Model, Adaptive Range Multi Objective Genetic Algorithms, Analysis of Variance and Self-Organizing Map. The main emphasis of this approach is visual data mining. An MDO system using high fidelity simulation codes, Navier-Stokes solver and NASTRAN, has been developed and applied to a regional-jet wing design. Because the optimization system becomes very computationally expensive, only brief exploration of the design space has been performed. However, data mining result demonstrates that design knowledge can produce a good design even from the brief design exploration.

• Ocean and Polar Research
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• v.27 no.1
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• pp.97-108
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• 2005

The International Seabed Authority (ISA) formally came into existence upon the entry into force of the UNCLOS on 16 November 1994. By adopting the Implementing Agreement in 1994, UNCLOS has the universality as a Magna Carta of International Ocean Regime, and the Deep Seabed Mining Regime could be operated as a unique one for the benefit of mankind. During last 10 years, ISA established the institutional framework successfully and made substantial and tangible progress in formulating the rules, regulations and procedures for the prospecting and exploration for polymetally nodules. Furthermore, RPI's obligations had been carried out completely, and the 7 RPI made contract with ISA to become a contractor who has an at least 15 you exclusive right for exploration in their allocated site. However, due to the uncertainty of commercial mining, the number of representatives from developing countries has been getting looser and looser and ISA has a problem of quorum of the Assembly. Land-based producers took a very strong opposite position to the contractors to make their loss in the minimum level. For the next decade, it might be prospected that ISA will focus on monitoring the contractor's activities, making rules, regulations and procedures for exploration on cobalt rich crust, sulphide and methane hydrate and implementing environment studies.

• 한국지구물리탐사학회:학술대회논문집
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• 1999.08a
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• pp.156-175
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• 1999

Recently the application of geophysical well logging to geotechnical site investigation is increasing, because the merit that geophysical logs provide the high resolution and in-situ physical properties in volumes of rock surrounding the borehole. Geophysical well logs are used to identify lithologic boundaries and fracture, to determine the physical properties of rock(i.e., density, velocity etc.), and to detect permeable fracture zones that could be conduits for ground water movement through the rocks. The principle of heat-pulse meter, the calibration of gamma-gamma logging, and principles and data processing of full waveform sonic logging are briefly reviewed, and the case studies of geophysical logs are discussed. Correlation between velocity by sonic logging and rock mass classification such as RMR(Rock Mass Rating) value is considered.