• 건축사
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• 통권482호
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• pp.77-80
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• 2009

• 건축사
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• 통권483호
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• pp.80-85
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• 2009

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4481-4485
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• 2012

Background: Chemotherapy induced leutropenia has been shown to be associated with improved treatment outcomes in selected solid tumors. We studied the association of chemotherapy induced leutropenia with treatment related outcomes in advanced non-small-cell lung cancer. Methods: This is a prospective analysis of patients receiving chemotherapy for advanced NSCLC at the Shandong Cancer Hospital from 2005-07.The chemotherapy included cisplatin $35mg/m^2$, IV on $d_{1,2}$ and vinorelbine $25mg/m^2$ IV on $d_{1,8}$ every 21 days. Patients were stratified into three groups (A) those experiencing grades 0 leucopenia, group (B) grades 1-2 and group (C) grades 3-4. The outcomes studied were response rate (RR), disease control rate (DCR), and time to progression (TTP). Results: 128 patients were studied. The RRs in groups A, B and C were 30.8%, 56.8% and 71.4%, respectively, p=0.010. The DCRs were 61.5%, 83.8% and 92.9%, respectively, p=0.009 and the median TTPs were 150 days (95%CI: 91-209), 189 days (95%CI: 181-197) and 207 days (95%CI: 172-242), p=0.009. The differences in RR and TTP were significant. In patients whose CIL kept on 10 days at least, the TTP was significantly prolonged, p=0.0213, and the same was the case for those experiencing grades 1-2 leucopenia and ECOG 0, p=0.0412. Conclusions: Occurrence of CIL correlated with RR and TTP in patients with advanced NSCLC receiving cisplatin and vinorelbine chemotherapy, especially in patients experiencing grades 1-2 leucopenia and ECOG 0, and the same for those with CIL persisting for 10 days at least. CIL could be a biological measure of drug activity and a marker of efficacy.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권2호
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• pp.105-111
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• 2017

Background: Dental fear is usually associated with hemodynamic changes. Fear of pain during the surgical removal of a lower impacted third molar might cause patients anxiety, thereby leading to avoidance of any future dental therapy. This study aimed to determine the effect of experiencing a surgical impacted-tooth removal on the pain perception-related anxiety and hemodynamic status. Method: Twenty-seven healthy patients aged 15-30 years (mean age, 24 years), for whom surgical removal of bilateral lower third molars was advised, were included. This prospective, randomized, controlled, split-mouth study involved operations on both sides of the mandibular arch, with a 1-month washout period in between. Blood pressure and heart rate were measured before the surgical procedure, during and after the injection, preoperatively, and postoperatively. Pain perception was evaluated using a 100-mm visual analog scale during the injection, preoperatively, and postoperatively after the numbness disappeared. Differences in the blood pressure, heart rate, and pain perception between the two appointments were analyzed using the paired t-test. For all statistical analyses, SPSS version 11.5 was used. Results: The mean pain perception values during the injection and preoperatively showed no significant differences between the two appointments (P > 0.05); however, significant differences in the blood pressure and heart rate were noted before the surgical procedure; preoperatively, the blood pressure alone showed a significant difference (P < 0.05). Conclusion: There was a significant decrease in the blood pressure and heart rate preoperatively; hence, experiencing a surgical impacted-tooth removal can reduce the subsequent preoperative anxiety in healthy patients.

• 농촌계획
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• 제14권3호
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• pp.1-9
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• 2008

In this study, by reflecting flow of age, possibility of new theme park development as private investments business based on source that is farming village that is not tried to before is verified and by analyzing potential of the site, effectiveness of new theme park development is examined. "Nonghyup Anseong Meadow Anseong-si Gyeonggi-do" is selected as researched site where accessibility is good as there is near to National Capital region and nature condition is also good. Demands are forecasted using visiting intention and realizing index through analogical method and by analyzing existing data related with increase of tourism business that people can experience English village and increasing demand of experiencing farming region tourism demands are forecasted. The results are at below. First, As average expenditure per one person is 52,209 won that is shown in result of survey, if multiplying increasing rate of price and the number of visiting people that is optimistic forecasting figure, the whole expenditure of visitors per one year is from 10.54 billions to 13.85 billions won. Second is potential power of demand aspects. Potential power of that theme park was re-examined through demands forecasting analysis through survey. Experiencing farming regions theme park business that is informed through analysis of potential power of development and demand aspects has value to invest as new business based on farming regions sources, as a result of searching through diverse aspects such as tourism, economy, public interest and cultural aspect and so on.

• 감성과학
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• 제5권4호
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• pp.45-49
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• 2002

가상환경시스템은 매우 현실감 있는 정보를 제공할 수 있다는 점에서 산업, 의료, 교육훈련 등에 널리 사용되고 있다. 그러나 아직 많은 가상환경 시스템에서 부정적 요인으로 멀미, 시각피로, 방향감각 상실로 대표되는 cybersickness중세를 수반하고 있어 그 사용과 확산에 제약이 되고 있다. 이러한 cybersickness문제에 대응하기 위해서는 우선 이것을 객관적으로 측정, 평가할 수 있는 방법의 개발이 필요하다. 이러한 방법들 중의 하나로 신체동요의 정도를 평가 지표로 사용할 수 있다. 이번 연구에서는 45 명의 피실험자들을 대상으로 가상현실 운전시뮬레이터를 운전하기 전과 후의 신체동요 정도를 힘판(force platform)을 이용해 측정하였다. 특히 본 실험에 사용된 가상현실 운전시뮬레이터는 피실험자에게 운동판(motion platform)을 이용해 운동감을 제공할 수 있었고, 피실험자의 멀미 현상이 검지되면, 시야각을 1/3로 줄여주는 멀미 완화 피드백(feedback) 시스템이 연결되어 있었다. 그래서 motion의 제공여부와 feedback의 제공 여부도 실험의 독립변수로 추가하였다. 실험 결과, 가상현실 체험 후 유의한 차이는 아니나 피실험자들의 신체동요가 약간 증가하는 것이 관측되었다. motion과 feedback에 대한 분석에서는, 유일하게 motion을 제공하는 것이 제공 안할 때에 비해 좌우 방향의 신체동요가 더 적어지는 것으로 나타났다. 신체동요를cybersickness의 지표로 사용하기 위해서는 추후연구가 더 요청된다.

• Journal of Preventive Medicine and Public Health
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• 제48권4호
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• pp.216-224
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• 2015

Objectives: Decreased fertility and impaired health owing to early menopause are significant health issues. Smoking is a modifiable health-related behavior that influences menopausal age. We investigated the effects of smoking-associated characteristics on menopausal age in Korean women. Methods: This study used data from the Korea National Health and Nutrition Examination Survey from 2007 to 2012. Menopausal age in relation to smoking was analyzed as a Kaplan-Meier survival curve for 11 510 women (aged 30 to 65 years). The risk of entering menopause and experiencing early menopause (before age 48) related to smoking were assessed using a Cox proportional hazards model. Results: The menopausal age among smokers was 0.75 years lower than that among non-smokers (p<0.001). The results of the Cox proportional hazards model showed pre-correction and post-correction risk ratios for entering menopause related to smoking of 1.26 (95% confidence interval [CI], 1.09 to 1.46) and 1.27 (95% CI, 1.10 to 1.47), respectively, and pre-correction and post-correction risk ratios for experiencing early menopause related to smoking of 1.36 (95% CI, 1.03 to 1.80) and 1.40 (95% CI, 1.05 to 1.85), respectively. Conclusions: Smokers reached menopause earlier than non-smokers, and their risk for experiencing early menopause was higher.

• Journal of Preventive Medicine and Public Health
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• 제40권2호
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• pp.145-149
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• 2007

Objectives : This study characterized the extent to which youth depressive symptoms, parental alcohol problems, and parental drinking account for differences in alcohol-related problems among a large sample of adolescent females. Methods : The stratified sample consists of 2077 adolescent females from twelve female-only high schools located in a large metropolitan city in the Republic of Korea. Students completed a questionnaire about alcohol use and alcohol problems, their parents' alcohol problems, and a number of risk and protective factors. Data were analyzed using tobit regression analyses to better characterize the associations among variables. Results : Almost two-thirds of students who consume alcohol had experienced at least one to two alcohol-related problems in their lives and 54.6% reported at least one current symptom of depression, with nearly one-third reporting two depressive symptoms. Two-thirds of the students indicated that at least one parent had an alcohol-related problem, and that approximately 29% had experienced several problems. Results of tobit regression analyses indicate that youth alcohol-related problems are positively associated with depressive symptoms (p<0.01) and parent drinking problems (p<0.05). Parental drinking is no longer significant when the variable parental attention is added to the model. Decomposition of the tobit parameters shows that for every unit of increase in depressive symptoms and in parent drinking problems, the probability of a youth experiencing alcohol problems increases by 6% and 1%, respectively. For every unit of increase in parental attention, the probability of youth experiencing drinking problems decreases by 5%. Conclusions : This study presents evidence that alcohol-related problems and depressive symptoms are highly prevalent among adolescent females. Although a comprehensive public health approach is needed to address drinking and mental health problems, different interventions are needed to target factors associated with initiation of alcohol problems and those associated with increased alcohol problems among those who already began experiencing such problems.

• 디지털융복합연구
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• 제17권1호
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• pp.259-267
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• 2019

본 연구는 임상실습을 경험한 간호대학생의 임파워먼트, 표준주의지침 인지도 및 수행도의 관련성을 파악하고, 간호대학생의 표준주의지침 수행도에 미치는 영향요인을 규명하기 위해 시도되었다. 연구 대상자는 전남지역 2개 대학의 임상실습을 경험한 간호대학생 168명을 대상으로 하였다. 수집된 자료는 IBM SPSS Statistics 20.0 프로그램을 이용하여 기술통계, t-test, ANOVA, Scheffe, Pearson's correlation coefficient, stepwise multiple regression을 통해 분석하였다. 단계적 다중회귀분석결과 표준주의지침 수행도에 영향을 미치는 요인은 인지도였으며 이들의 설명력은 77.7%였다(F=579.84, p<.001). 본 연구결과를 바탕으로 임상실습을 경험한 간호대학생의 표준주의지침 수행도를 증진시키기 위한 표준주의지침 인지도를 높이기 위한 방안이 필요할 것으로 생각된다.

• 한국심리학회지 : 문화 및 사회문제
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• 제15권4호
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• pp.565-589
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• 2009

본 연구에서는 게임 사용의 부정적 결과에 초점을 둔 선행 연구와 달리, 게임활용의 긍정적 결과로서의 적응적 게임활용도를 측정하는 도구를 개발하고 타당화하였다. 예비조사를 통해 적응적 게임활용 측정 도구를 개발하고, 유층표집을 통해 선정된 전국 중고등학생 600명을 대상으로 본조사를 실시하였다. 연구결과 활력 경험, 생활경험 확장, 여가 선용, 몰입 경험, 자긍심 경험, 통제력 경험, 사회적 지지망 유지 및 확장 등 7개의 요인으로 구성되는 척도의 신뢰도와 시간에 걸친 안정성이 확인되었다. 또한, 척도의 구성타당도, 변별타당도, 및 공인타당도를 확인하였다. 게임 연구의 외연 확장과 관련한 본 연구의 시사점과 장래 연구 방향을 논의하였다.