• Title/Summary/Keyword: Expected effect

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Effects of the Type and Number of Enrichment on Growth Performance, Blood Characteristics, Footpad Dermatitis, and Litter Moisture in Broilers (Enrichment 종류 및 개수 설정에 따른 육계 생산성, 혈액특성, 발바닥피부염, 깔짚 내 수분함량에 미치는 영향)

  • Hyunsoo, Kim;Hee-Jin, Kim;Jin-Joo, Jeon;Jiseon, Son;Yeon-Seo, Yun;Eui-Chul, Hong;Hwan-Ku, Kang
    • Korean Journal of Poultry Science
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    • v.49 no.4
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    • pp.199-210
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    • 2022
  • This study was conducted to investigate the effects of the type and number of enrichments on growth performance, blood characteristics, footpad dermatitis (FPD) incidence, and litter moisture in broilers. A total of 1,140 1-day-old male Ross 308 broilers were assigned to a 3 × 2 factorial arrangement based on the type of enrichment (cabbage, alfalfa block, and angle sawdust) and the number of enrichments (one or two per 38 broilers). The growth performance, blood characteristics, FPD incidence, and litter moisture of the broilers were evaluated. Body weight and feed conversion rate were significantly improved (P<0.05) in the alfalfa block and sawdust group compared to the cabbage group, but there was no interaction effect between the type and number of enrichments. The heterophil/lymphocyte ratio, a stress index, was significantly decreased (P<0.05) in the alfalfa block and sawdust groups compared with the cabbage group. The incidence of FPD was significantly decreased in the order of cabbage (3.78), alfalfa block (3.06), and sawdust (1.43) groups at 5 weeks of age. Moreover, there was a significant decrease in the incidence of FPD (P<0.05) in the one-enrichment group compared with the two-enrichment group. Litter moisture at 5 weeks of age was significantly reduced in the sawdust group compared to the cabbage and alfalfa groups, but there was no significant difference in the interaction between the type and number of enrichments. It was concluded that sawdust enrichment positively influenced both growth performance and the animal welfare of broilers. In addition, it is expected that sawdust can be used to regulate litter moisture.

Antioxidative Effects of Tenebrio molitor Larvae Extract Against Oxidative Stress in ARPE-19 Cells (ARPE-19 세포에서 산화적 스트레스에 대한 갈색거저리 추출물의 항산화 효과)

  • Bong Sun, Kim;Ra-Yeong, Choi;Eu-Jin, Ban;Joon Ha, Lee;In-Woo, Kim;Minchul, Seo
    • Journal of Life Science
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    • v.32 no.11
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    • pp.865-871
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    • 2022
  • Tenebrio molitor larvae is well known as edible insect. Then, although it has been widely studied that Tenebrio molitor larvae has various bioactive functions such as antioxidant, anti-wrinkle, and anticancer. Nevertheless, antioxidant effects of Tenebrio molitor larvae water extract (TMH) has not been well described in Adult Retina Pigment Epithelial cell line (ARPE-19). In this study, we demonstrated that antioxidant effects of TMH against H2O2-induced oxidative stress in ARPE-19. Thus, we selected for our studies and performed a series of dose-response assay to determine the working concentration that lead to a consistent and high degree of cytotoxicity, which we defined as the level of H2O2 that killed 40% of the ARPE-19 cells. ARPE-19 cells were pre-treated with various concentrations of TMH (0.1 up to 2 mg/ml) before exposure to 300 µM H2O2. As we expected, TMH effectively prevented ARPE-19 cells from 300 µM H2O2-induced cell death in a dose-dependent manner. Furthermore, TMH inhibited the phosphorylation of mitogen-activated protein kinases (MAPKs) such as extracellular signal regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38. Overall, the inhibitory effects of TMH on H2O2-induced apoptosis and oxidative stress were associated with the protection cleaved caspase-3, Bax, Bcl-2, and HO-1. The TMH suppressed H2O2-induced cell membrane leakage and oxidative stress in ARPE-19 cells. Thus, these results suggest that the TMH plays an important role in antioxidant effect in ARPE-19.

Changes of Plant Growth and Nutrient Concentrations of the Drainage According to Drainage Reuse and Substrate Type in Sweet Pepper Hydroponics (파프리카 수경재배 시 배액 재사용과 배지 종류에 따른 생육 및 배액 내 이온 농도 변화)

  • Lim, Mi Young;Jeong, Eun Seol;Roh, Mi Young;Choi, Gyeong Lee;Kim, So Hui;Lee, Choung Keun
    • Journal of Bio-Environment Control
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    • v.31 no.4
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    • pp.476-484
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    • 2022
  • This study was conducted to investigate the effect of closed cultivation and open cultivation method and substrate type on the nutrient ion change pattern and growth of sweet pepper (Capsicum annuum L.) 'Scirocco' according to the reuse of drainage in hydroponics. The sowing, transplanting, and application of the closed and open cultivation method were carried out on August 19 and September 16, and October 21, 2021, respectively. As a result of the analysis of nutrients in the drainage, Na+ and Cl- are representative ions that crops do not absorb properly, and as the growth progresses, they are accumulated in the closed method. In addition, since the content of NH4-N in the drainage is significantly lower than that of NO3-N, it is thought that NH4-N is preferentially absorbed rather than NO3-N due to the ion selectivity of sweet pepper. The growth and fruit characteristics of sweet pepper did not differ significantly between treatments according to the drainage reuse and the type of substrate. In conclusion, if you take care of poor fruiting due to the weakening of power after the middle period in hydroponic cultivation of sweet pepper according to the cultivation method of closed and open, and the substrate type of coir and rock wool, the difference between treatments is not large, so the sweet pepper can be produced by selecting the cultivation methods and substrate types suitable for the conditions of grower. However, as interest in environmental pollution has recently increased, it is judged that there is no need to worry about a decrease in quantity or quality, even if a closed cultivation method is adopted under the assumption that pathogen infection due to drainage reuse is well managed. It is expected that if coir is applied instead of rock wool, which causes a problem of disposal, it will further contribute to the reduction of environmental pollution.

The Effect of Domain Specificity on the Performance of Domain-Specific Pre-Trained Language Models (도메인 특수성이 도메인 특화 사전학습 언어모델의 성능에 미치는 영향)

  • Han, Minah;Kim, Younha;Kim, Namgyu
    • Journal of Intelligence and Information Systems
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    • v.28 no.4
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    • pp.251-273
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    • 2022
  • Recently, research on applying text analysis to deep learning has steadily continued. In particular, researches have been actively conducted to understand the meaning of words and perform tasks such as summarization and sentiment classification through a pre-trained language model that learns large datasets. However, existing pre-trained language models show limitations in that they do not understand specific domains well. Therefore, in recent years, the flow of research has shifted toward creating a language model specialized for a particular domain. Domain-specific pre-trained language models allow the model to understand the knowledge of a particular domain better and reveal performance improvements on various tasks in the field. However, domain-specific further pre-training is expensive to acquire corpus data of the target domain. Furthermore, many cases have reported that performance improvement after further pre-training is insignificant in some domains. As such, it is difficult to decide to develop a domain-specific pre-trained language model, while it is not clear whether the performance will be improved dramatically. In this paper, we present a way to proactively check the expected performance improvement by further pre-training in a domain before actually performing further pre-training. Specifically, after selecting three domains, we measured the increase in classification accuracy through further pre-training in each domain. We also developed and presented new indicators to estimate the specificity of the domain based on the normalized frequency of the keywords used in each domain. Finally, we conducted classification using a pre-trained language model and a domain-specific pre-trained language model of three domains. As a result, we confirmed that the higher the domain specificity index, the higher the performance improvement through further pre-training.

Analysis of Economic and Environmental Effects of Remanufactured Furniture Through Case Studies (사례분석을 통한 사용 후 가구 재제조의 경제적·환경적 효과 분석)

  • Lee, Jong-Hyo;Kang, Hong-Yoon;Hwang, Yong Woo;Hwang, Hyeon-Jeong
    • Resources Recycling
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    • v.31 no.5
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    • pp.67-76
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    • 2022
  • The furniture industry has a high possibility to create value-added and a high potential to create new occupations due to the characteristics of the industry, which mainly consists of small and medium-sized enterprises (SMEs). However, the used furniture, which has sufficient reuse value, is also crushed and used as solid refuse fuel (SRF) recently. Besides, the number of waste treatment companies continues to decrease, and it occurs congestion of wood waste. As a way to solve the issue, a business model development of remanufacturing used furniture can be suggested as an alternative due to its high circular economic efficiency. Remanufacturing business including furniture industry creates positive effects in various aspects such as economic, environmental and job creation. In other words, remanufacturing is an effective recycling way to reduce input resources and energy in the production process. The results of economic analysis show that the expected annual revenue from the single worker furniture remanufacturing site was 104 million won which is 3.11 times more than the average income of a single-worker household in Korea and its B/C ratio was estimated about 30 which means high business feasibility. Revenue through furniture remanufacturing also showed 320 times higher than that of SRF production from the perspective of weight. In addition, it is shown that the GHGs reduction from the furniture remanufacturing is 2.2 ton CO2-eq. per year, which is similar to the amount of GHGs absorption effect of 937 pine trees or 622 Korean oak trees annually. Thus the results of this study demonstrate that it is important to adopt an appropriate recycling method considering the economic and environmental effects at the end-of-life stage.

Development of tracer concentration analysis method using drone-based spatio-temporal hyperspectral image and RGB image (드론기반 시공간 초분광영상 및 RGB영상을 활용한 추적자 농도분석 기법 개발)

  • Gwon, Yeonghwa;Kim, Dongsu;You, Hojun;Han, Eunjin;Kwon, Siyoon;Kim, Youngdo
    • Journal of Korea Water Resources Association
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    • v.55 no.8
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    • pp.623-634
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    • 2022
  • Due to river maintenance projects such as the creation of hydrophilic areas around rivers and the Four Rivers Project, the flow characteristics of rivers are continuously changing, and the risk of water quality accidents due to the inflow of various pollutants is increasing. In the event of a water quality accident, it is necessary to minimize the effect on the downstream side by predicting the concentration and arrival time of pollutants in consideration of the flow characteristics of the river. In order to track the behavior of these pollutants, it is necessary to calculate the diffusion coefficient and dispersion coefficient for each section of the river. Among them, the dispersion coefficient is used to analyze the diffusion range of soluble pollutants. Existing experimental research cases for tracking the behavior of pollutants require a lot of manpower and cost, and it is difficult to obtain spatially high-resolution data due to limited equipment operation. Recently, research on tracking contaminants using RGB drones has been conducted, but RGB images also have a limitation in that spectral information is limitedly collected. In this study, to supplement the limitations of existing studies, a hyperspectral sensor was mounted on a remote sensing platform using a drone to collect temporally and spatially higher-resolution data than conventional contact measurement. Using the collected spatio-temporal hyperspectral images, the tracer concentration was calculated and the transverse dispersion coefficient was derived. It is expected that by overcoming the limitations of the drone platform through future research and upgrading the dispersion coefficient calculation technology, it will be possible to detect various pollutants leaking into the water system, and to detect changes in various water quality items and river factors.

A comparative study of risk according to smoke control flow rate and methods in case of train fire at subway platform (지하철 승강장에서 열차 화재 시 제연풍량 및 방식에 따른 위험도 비교 연구)

  • Ryu, Ji-Oh;Lee, Hu-Yeong
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.24 no.4
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    • pp.327-339
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    • 2022
  • The purpose of this study is to present the effective smoke control flow rate and mode for securing safety through quantitative risk assessment according to the smoke control flow rate and mode (supply or exhaust) of the platform when a train fire occurs at the subway platform. To this end, a fire outbreak scenario was created using a side platform with a central staircase as a model and fire analysis was performed for each scenario to compare and analyze fire propagation characteristics and ASET, evacuation analysis was performed to predict the number of deaths. In addition, a fire accident rate (F)/number of deaths (N) diagram (F/N diagram) was prepared for each scenario to compare and evaluate the risk according to the smoke control flow rate and mode. In the ASET analysis of harmful factors, carbon monoxide, temperature, and visible distance determined by performance-oriented design methods and standards for firefighting facilities, the effect of visible distance is the largest, In the case where the delay in entering the platform of the fire train was not taken into account, the ASET was analyzed to be about 800 seconds when the air flow rate was 4 × 833 m3/min. The estimated number of deaths varies greatly depending on the location of the vehicle of fire train, In the case of a fire occurring in a vehicle adjacent to the stairs, it is shown that the increase is up to three times that of the vehicle in the lead. In addition, when the smoke control flow rate increases, the number of fatalities decreases, and the reduction rate of the air supply method rather than the exhaust method increases. When the supply flow rate is 4 × 833 m3/min, the expected number of deaths is reduced to 13% compared to the case where ventilation is not performed. As a result of the risk assessment, it is found that the current social risk assessment criteria are satisfied when smoke control is performed, and the number of deaths is the flow rate 4 × 833 m3/min when smoke control is performed at 29.9 people in 10,000 year, It was analyzed that it decreased to 4.36 people.

Estimation of Carbon Stock and Annual CO2 Uptake of Four Species at the Sejong National Arboretum - Pinus densiflora, Metasequoia glyptostroboides, Aesculus turbinata, Chionanthus retusus - (국립세종수목원 교목 4종의 탄소 저장량 및 연간 이산화탄소 흡수량 평가 - 소나무, 메타세쿼이아, 칠엽수, 이팝나무를 대상으로 -)

  • Hak Koo KIm;Yong Sik Hong;Yun Kyung Lim;I Seul Yun;Ki Seok Do;Chan Hyung Jung;Chi Mun Lee;Hoi Eun Roh;Sin Koo Kang;Chan-Beom Kim
    • Journal of Environmental Impact Assessment
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    • v.32 no.1
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    • pp.41-48
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    • 2023
  • This study was conducted to confirm the possibility of a new carbon stock in the Sejong National Arboretum, a major urban greenspace in Sejong-si. This study involved field and ground surveys of 1,336 trees, including 794 Pinus densiflora trees with a diameter at breast height (DBH) of above 5.5cm, which are the most planted in the Sejong National Arboretum, Chionanthus retusus 154 trees planted, Metasequoia glyptostroboides 216 trees, and Aesculus turbinata 172 trees as street trees. Measurements were performed from April to November. Based on the results of the survey, the carbon storage and annual carbon stock were calculated using the annual carbon stock estimation equation used in the forest carbon offset projects. As a result of comparing the carbon stock of the 12cm diameter class, which is the most distributed of four major trees, it was found in the order of C. retusus (0.0136tC/tree), P. densiflora (0.0126tC/tree), M. glyptostroboides (0.0092tC/tree), and A. turbinata (0.0076tC/tree). In addition, the field survey measurement data compared with terrestrial LiDAR measurement data for 20 trees showed a difference of 10.0cm in tree height and 1.7cm in diameter at breast height (p<0.05). In the future, additional carbon stock and annual uptake of other species planted in the arboretum are expected to promote the carbon uptake effect of the arboretum and contribute to the achievement of the national NDC. In the long term, it is also necessary to develop the carbon uptake factor of trees and shrubs mainly used to calculate the exact carbon uptake amount of trees mainly used in urban forests and gardens.

Tyrosinase Inhibition-mediated Anti-melanogenic Effects by Catechin Derivatives Extracted from Ulmus parvifolia (참느릅나무에서 추출된 catechin 유도체 화합물의 멜라닌 생성 억제 효과)

  • Taehyeok Hwang;Hyo Jung Lee;Dong-Min Kang;Kyoung Mi Moon;Jae Cheal Yoo;Mi-Jeong Ahn;Dong Kyu Moon;Dong Kyun Woo
    • Journal of Life Science
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    • v.33 no.2
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    • pp.169-175
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    • 2023
  • As a protective defensive mechanism against ultraviolet (UV) light exposure in skin tissue, melanocytes produce the pigment melanin. Tyrosinase plays a key role in melanin production in melanocytes. However, the overproduction of melanin can lead to lesions, such as freckles and dark spots. Thus, it is clinically important to find a modulating molecule to control melanogenesis by regulating tyrosinase expression and/or activity. It is known that catechin, a plant flavonoid, can reduce melano- genesis through the downregulation of tyrosinase expression. Here, we tested whether catechin derivatives isolated from the stem bark of Ulmus parvifolia have an effect on melanin production by regulating tyrosinase in mouse melanoma cells and in vitro mushroom tyrosinase. The catechin derivatives used in this study included C5A, C7A, C7G, and C7X. Treatments using these catechin derivatives reduced melanin production in mouse melanoma B16F10 cells in which melanogenesis was stimulated by α-MSH. Notably, the anti-melanogenic effects of catechin derivatives were similar to those of kojic acid, a well-known anti-melanogenic molecule. Both C5A and C7A directly inhibited the activity of tyrosinase isolated from mushrooms in vitro. Furthermore, our in silico computational simulation showed that these two compounds were expected to bind to the active site of tyrosinase, which is similar to kojic acid. In addition, all four catechin derivatives reduced tyrosinase protein expression. In summary, our results showed that catechin derivatives can reduce melanogenesis by regulating tyrosinase activity or expression. Thus, this study suggests that catechin derivatives isolated from U. parvifolia can be novel modulators of melanin production.

Factors Affecting Physicians who will be Vaccinated Every Year after Receiving the COVID-19 Vaccine in Healthcare Workers (의료종사자의 COVID-19 예방 백신 접종받은 후 향후 매년 예방접종 의향에 미치는 요인)

  • Hyeun-Woo Choi;Sung-Hwa Park;Eun-Kyung Cho;Chang-hyun Han;Jong-Min Lee
    • Journal of the Korean Society of Radiology
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    • v.17 no.2
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    • pp.257-265
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    • 2023
  • The purpose of this study was to vaccinate every year according to the general characteristics of COVID-19, whether to vaccinate every year according to the vaccination experience, whether to vaccinate every year according to knowledge/attitude about vaccination, and negative responses to the vaccinate every year In order to understand the factors affecting the vaccination physician every year by identifying the factors of Statistical analysis is based on general characteristics, variables based on vaccination experience, and knowledge/attitudes related to vaccination. The doctor calculates the frequency and percentage, A square test (-test) was performed, and if the chi-square test was significant but the expected frequency was less than 5 for 25% or more, a ratio difference test was performed with Fisher's exact test. Through multiple logistic regression analysis using variables that were significant in simple analysis, a predictive model for future vaccination and the effect size of each independent variable were estimated. As statistical analysis software, SAS 9.4 (SAS Institute Inc., Cary, NC, USA) was used, and because the sample size was not large, the significance level was set at 10%, and when the p-value was less than 0.10, it was interpreted as statistically significant. In the simple logistic regression analysis, the reason why they answered that they would not be vaccinated every year was that they answered 'to prevent infection of family and hospital guests' rather than 'to prevent my infection' as the reason for the vaccination. It was 11.0 times higher and 3.67 times higher in the case of 'for the formation of collective immunity of the local community and the country'. The adverse reactions experienced after the 1st and 2nd vaccination were 8.42 times higher in those who did not experience pain at the injection site than those who did not, 4.00 times higher in those who experienced swelling or redness, and 5.69 times higher in those who experienced joint pain. There was a 5.57 times higher rate of absenteeism annually than those who did not. In addition, the more anxious they felt about vaccination, the more likely they were to not get the vaccine every year by 2.94 times.