• Journal of Korean Medical classics
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• v.19 no.3
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• pp.421-426
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• 2006

Objective To learn if there were different characteristics of tongue demonstration between diseases caused by exogenous pathogenic factor and disorder of internal organs. Methods Choosing 3059 cases from 51 medical records of Qing Dynasty, in which 1397 cases were diagnosed as diseases caused by exogenous pathogenic factor and 1110 were disorder of internal organs. Contrasting the constituent ratio of tongue demonstration using chi-square test. Results There were significant deviation between diseases caused by exogenous pathogenic factor and disorder of internal organs in color of tongue, color of fur and quality of fur (p<0.01). Conclusions the characteristics of tongue demonstration in diseases caused by exogenous pathogenic factor were high frequency of bright red tongue, yellow fur, blank fur and dry fur; and which in disorder of internal organs were high frequency of white tongue, thin fur, greasy fur and exfoliative fur.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.43 no.4
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• pp.59-66
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• 2020

In this study, we consider the problem of forecasting the number of inbound foreigners visiting Korea. Forecasting tourism demand is an essential decision to plan related facilities and staffs, thus many studies have been carried out, mainly focusing on the number of inbound or outbound tourists. In order to forecast tourism demand, we use a seasonal ARIMA (SARIMA) model, as well as a SARIMAX model which additionally comprises an exogenous variable affecting the dependent variable, i.e., tourism demand. For constructing the forecasting model, we use a search procedure that can be used to determine the values of the orders of the SARIMA and SARIMAX. For the exogenous variable, we introduce factors that could cause the tourism demand reduction, such as the 9/11 attack, the SARS and MERS epidemic, and the deployment of THAAD. In this study, we propose a procedure, called Measuring Impact on Demand (MID), where the impact of each factor on tourism demand is measured and the value of the exogenous variable corresponding to the factor is determined based on the measurement. To show the performance of the proposed forecasting method, an empirical analysis was conducted where the monthly number of foreign visitors in 2019 were forecasted. It was shown that the proposed method can find more accurate forecasts than other benchmarks in terms of the mean absolute percentage error (MAPE).

• The Journal of Internal Korean Medicine
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• v.12 no.1
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• pp.19-30
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• 1991

By the literatural study of chest pain (Sim-Tong), I have been obtained following conclusions. This conclusions driveed into the 'Sam-In-Guk-Il-Beung-Jung-Bang-Ron' written by the Jin, Moo-Taek. 1. Chil-jung(seven modes of emotions), Gi-Yeuk(abnomal risting of vital energy), Yang-hue(deficiency of Yang) are the chief endogenouse factor of chest pain. 2. Han-sa(cold-evil), Euk-Em(six-evils), Pung-Han-Yeol-Sa (wind-cold-heat-evils) are the exogenous factor of chest pain, and Han-Sa(cold-evil) is chief factor among them. 3. Dam-Em(phlegm-retention disease), Jeong-Sik(undigestive meal), Hoi-Chung(ascaris), Sa-Heol(blood stasis) are the chief pathologic factor neither endogenous nor exogenous of chest pain.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.4
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• pp.51-56
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• 2010

Objectives and Methods : This study was performed to know about the reason of pain, the type of pain, etc. from "Somun(素問)" and "Yeongchu(靈樞)" of "Hwangjenaegyeong(黃帝內經)". And then we recognized the rational Korean medical physiotherapy about the pain control. Results : There was well described about the pain in "Hwangjenaegyeong(黃帝內經)". It was explained that the reason of pain was cold pathogenic factor one of the six exogenous pathogens. If the body was cold and qi-blood was lack of free flow, and the pain was occurred. Conclusions : According to above results, warming the meridian therapy is rational Korean medical physiotherapy about the pain control. An that gives positive effect about the pain control.

• Asia pacific journal of information systems
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• v.11 no.3
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• pp.105-126
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• 2001

The objective of research is to find out exogenous variables that influence the usage and performance EDI in the Korea firms. Specifically the goals of this research are; (1) to examine relationships between exogenous variables, such as management, technology, inter-firm relationship characteristics, and EDI performance, and (2) to measure EDI volume, EDI diversity, EDI depth among Korea firms. The questionnaire consists of two versions; One for the EDI system managers and the other for the EDI users. The analysis of this study is designed as cross level to examine the causal relationship among variables in different analysis level. The reliability and validity of data was tested by explanatory factor analysis, Cronbach's alpha coefficient, confirmatory factor analysis, and correlation analysis. Also, the structural equation model(SEM) analysis was performed to test the usefulness of the model. The analysis results revealed that education level, IS growth, trust, support, power are major influential variables on the usage level and performance of EDI. Especially, persuasive power turned out to be more important than coercive power, and technical financial support from organizations was also found to be a significant variables.

• Journal of the Korean Society of Costume
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• v.28
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• pp.137-150
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• 1996

The objectives of this study were to classify daily clothing selection motives and to group men into life style types and to examine the differences in daily clothing selection motives according to the life style types. Questionnaire comprised of three sections: 36 Likert type items of life style measure; 29 Likert type items of daily clothing selection motives measure: and 4 demographic variables. Samples were 267 salary men in gheir 20's to 30's in Seoul Korea. The data were analyzed using factor analy-sis cluster analysis one-way ANOVA Dun-can's multiple range test and t-test. 1. Five factors of life style were derived by factor analysis ; F. 1 'appearance oriented' f. 2. 'positive activity' F. 3 'economy oriented': F.4 'active-leisure';F. 5 'contemporary' Four types of life style of men were defined by cluster analysis of the five factors: T. 1'posi-tive activity'; T. 2.'economy interest'; T. 3'contemporary' : T 2'economy interest' T.3'contemporary' ; T. 4 'appearance interest' 2. Four factors of daily clothing selection motives were derived by factor analysis: F.1 'clothing harmony'; F.2 'clothing utility'; F.3 'psychological influence'; F.4 'exogenous situ-ation adaptation 3. There were significant differences in daily clothing selection motives according to the life style types. The types of positive activity economy interest and contemporary had 'clothing utility' motive more than appearance interest type. Economy interest type had 'hpsychological influence' motive more than other three types. Economy interest type and appearance interest type had 'exogenous situ-ation adaptation' motive more than other two types 4. 20's and unmarried men had'psychological influence' motive more than 30's and married. Upper class had 'clothing harmony' and 'ex-ogeneous situation adaptation' motives more than middle and low. Men with less education had ' clothing utility' and 'exogenous situation adaptation' motives more than did more edu-cation.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.34 no.3
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• pp.939-945
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• 2014

In most of mobility enhancing plans for the transportation disabled, decisions for the investment priorities are firstly made by the facilities that have lower installation rate or lower satisfaction rate; the decisions are made without analyzing the importance factor (path loading factor) between the facility installation rate and the satisfaction rate together. In this study, a novel method of finding causality between the exogenous latent variables and the endogenous latent variables is provided by using the Structural Equation Model (SEM). The results show that the most influential facilities for the transportation disabled are bus stops, crosswalks and sidewalks in order. Also, a curb height around bus stops, a smoothness of sidewalks and installation of crosswalks traffic light are identified as an important facilities for the Transportation disabled.

• Reproductive and Developmental Biology
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• v.36 no.1
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• pp.33-37
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• 2012

Differential capacity of the parthenogenetic embryonic stem cells (PESCs) is still under controversy and the mechanisms of its neural induction are yet poorly understood. Here we demonstrated neural lineage induction of PESCs by addition of insulin-like growth factor-2 (Igf2), which is an important factor for embryo organ development and a paternally expressed imprinting gene. Murine PESCs were aggregated to embryoid bodies (EBs) by suspension culture under the leukemia inhibitory factor-free condition for 4 days. To test the effect of exogenous Igf2, 30 ng/ml of Igf2 was supplemented to EBs induction medium. Then neural induction was carried out with serum-free medium containing insulin, transferrin, selenium, and fibronectin complex (ITSFn) for 12 days. Normal murine embryonic stem cells derived from fertilized embryos (ESCs) were used as the control group. Neural potential of differentiated PESCs and ESCs were analyzed by immunofluorescent labeling and real-time PCR assay (Nestin, neural progenitor marker; Tuj1, neuronal cell marker; GFAP, glial cell marker). The differentiated cells from both ESC and PESC showed heterogeneous population of Nestin, Tuj1, and GFAP positive cells. In terms of the level of gene expression, PESC showed 4 times higher level of GFAP expression than ESCs. After exposure to Igf2, the expression level of GFAP decreased both in derivatives of PESCs and ESCs. Interestingly, the expression level of $Tuj1$ increased only in ESCs, not in PESCs. The results show that IGF2 is a positive effector for suppressing over-expressed glial differentiation during neural induction of PESCs and for promoting neuronal differentiation of ESCs, while exogenous Igf2 could not accelerate the neuronal differentiation of PESCs. Although exogenous Igf2 promotes neuronal differentiation of normal ESCs, expression of endogenous $Igf2$ may be critical for initiating neuronal differentiation of pluripotent stem cells. The findings may contribute to understanding of the relationship between imprinting mechanism and neural differentiation and its application to neural tissue repair in the future.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.5
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• pp.857-866
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• 2002

The main current in the pathology of oriental medicine is composed of etiologic factor, pathogenesis and clinical manifestation. The access of a disease is consist of etiologic factor, location of the lesion, nature of the disease and patient's condition. The nature of disease and the property of a drug are inseparably related to each other. The nature of disease is composed of six exogenous factors, cold and heat, deficiendy and excess, Yinyang and pain. Cold nature is divided into cold symptom due to excess and asthenia cold, fever nature is divided into sthenic fever and asthenic fever. According to the location, cold and heat can be subdivided into heat in the upper and cold in the lower, cold in the upper and heat in the lower, exterior cold and interior heat, exterior heat and interior cold. Yin syndrome characterized by hypofunction of the viscera is generated from insufficiency of yang-qi, excess of yin-coldness, deficiency of both qi and the blood.

• Reproductive and Developmental Biology
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• v.36 no.1
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• pp.13-19
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• 2012

In order to provide the basis for developing practical mouse embryonic stem cells (mESCs) culture method, how the endogenous level of self-renewal-stimulating factor genes was altered in the mESCs by different extracellular signaling was investigated in this study. For different extracellular signaling, mESCs were cultured in 2 dimension (D), 3D and integrin-stimulating 3D culture system in the presence or absence of leukemia inhibitory factor (LIF) and transcriptional level of $Lif$, $Bmp4$ and $Wnt3a$ was evaluated in the mESCs cultured in each system. The expression of three genes was significantly increased in 3D system relative to 2D system under LIF-containing condition, while only $Wnt3a$ expression was increased by 3D culture under LIF-free condition. Stimulation of integrin signaling in mESCs within 3D system with exogenous LIF significantly up-regulated transcriptional level of $Bmp4$, but did not induce transcriptional regulation of $Lif$ and $Wnt3a$. In the absence of LIF inside 3D system, the expression of $Lif$ and $Bmp4$ was significantly increased by integrin signaling, while it significantly decreased $Wnt3a$ expression. Finally, the signal from exogenous LIF significantly caused increased expression of $Lif$ in 2D system, decreased expression of $Bmp4$ in both 2D and 3D system, and decreased expression of $Wnt3a$ in integrin-stimulating 3D system. From these results, we identified that endogenous expression level of self-renewal-stimulating factor genes in mESCs could be effectively regulated through artificial and proper manipulation of extracellular signaling. Moreover, synthetic 3D niche stimulating endogenous secretion of self-renewal-stimulating factors will be able to help develop growth factor-free maintenance system of mESCs.