• 동의생리병리학회지
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• 제20권6호
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• pp.1431-1441
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• 2006

Following conclusions were drawn from the examination of the usage of semen persicae and fols carthami from the view of Hyungsang Medicine. Semen persicae is used to vitalize the blood flow and eliminate the blood stagnation of the whole body in ${\ulcorner}$Donguibogam${\lrcorner}$, and therefor it is used for the blood flow of the heptal meridian and sometimes the intestinal meridian. Flos carthami is applied to vitalize the blood flow, remove obstructions in meridians, eliminate the blood stagnations, and stop the pain in ${\ulcorner}$Donguibogam${\lrcorner}$, therefore used in such symptoms of blood flow of the heptal meridian as amenorrhea, spasm of muscles, and coldness of the genitals. Also is applied in those cases of exhaustion, perspiration, and in digestive remedies which belong to the symptoms of cardiac blood flow. And it is used for dryness of the skin in which case the blood should be developed and malaria for the elimination of the blood stagnation and production of new blood. The combination of semen persicae and flos carthami is applied to eliminate the blood stagnation and stimulate menstrual discharge in uterus, as well as in the cases of lumbago and stomachache due to blood stagnation, blood stasis, mass in the abdomen, and abdominal distention. This combination is also used for the eyes, ears, numbness, and paralysis of hands and feet for the purpose of making the flow of the meridian smooth, and for diabetes, dryness of the skin, malaria, anal itching and pain for the purpose of eliminating the mass and renewing the tissues. The combination is diversly used in the book of ${\ulcorner}$Special lectures on clinical cases${\lrcorner}$ for the aftereffects of traffic accident, constipation, diabetes, dryness of the skin, paralysis of hands and feet, numbness of finger of hand and foot, and especially used frequently with prescription of Yijintang and Samultang combined in the cases of numbness. The prescription is used in Hyungsang medicine when the uterus, the external appearance(axis), hands and feet, heart, and the stomach is not good for the vitalization of the flow of the 12 meridians. It was though difficult to find extinguishing differences between the two herbs in the clinical cases applied in the book of ${\ulcorner}$Special lectures on clinical cases${\lrcorner}$.

• 동의생리병리학회지
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• 제26권1호
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• pp.10-18
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• 2012

In this paper, to find out how different the treatment of special individuals named 'old people' is with that of ordinary cases, Dongeuibogam(東醫寶鑑) was chosen as the study material and some parts in it where the symptoms of old people in the same disease category were treated in different ways were excerpted to analyze the tendency of pathological symptoms and prescriptions in the physiological perspective. As the result of analysis on the parts in Dongeuibogam(東醫寶鑑) where the old people were treated in different ways, it turned out that 65 prescriptions were used in 24 pathological symptoms. The 24 symptoms are included mainly in chapters of 'inner view(內景)' and 'outer form(外形)'. They are including the pathological symptoms which had been presented as general geriatric symptoms and also seems to have added other symptoms which should be clinically reflected in the specialty of treatment for geriatric diseases. The 65 prescriptions are also recorded mainly in chapters of 'inner view(內景)' and 'outer form(外形)'. The herbs used for them were sweet and warm herbs such as Rehmannia glutinosa (Gaertner) Libosch(熟地黃), Angelica gigas Nakai(當歸), Panax ginseng C. A. Mey(人蔘) and Atractylodes macrocephala Koidz(白朮) that can support the essence blood of liver and kidney and the energy of spleen, lung and stomach. Those herbs could be added or subtracted according to the symptom. It seems to have resulted from the treatment method that old people was applied to old people in consideration of their physiological features. When the 24 symptoms and 65 prescriptions for geriatric diseases different from ordinary ones in Dongeuibogam(東醫寶鑑) were considered in the physiological view point, it could be seen that each pathological symptom was manifested as a exhaustion of kidney qi(腎氣枯渴) which was a characteristic physiologic state of old people. Through this, it could be seen that the use of prescriptions was also made to mitigate the body fluid deficiency(津液不足), the kidney yin inner heat(腎陰內熱), the heart spirit void and loss(心神虛損), the kidney yang deficiency(腎陽不足), the spleen failing in transportation(脾失健運), the spleen yang deficiency(脾陽不足), the liver fire inner movement(肝火內動) and the lung energy void and loss(肺氣虛寒).

• 한국콘텐츠학회논문지
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• 제15권1호
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• pp.366-378
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• 2015

본 논문의 목적은 미국 자립생활센터 실무자들이 경험하는 직무스트레스의 정도를 파악하고, 이들의 직무스트레스와 소진간의 관계를 밝히기 위함이다. 온라인조사와 설문지 조사를 통하여 설문에 최종 참여한 자립생활센터 실무자는 총 218명인데 이들이 경험하는 직무스트레스 중 직무갈등(role conflict: RC)점수는 평균 22.48 (SD = 5.80)이며 직무모호성(role ambiguity: RA) 점수는 평균 22.20 (SD = 4.30), 직무과중(role overload: RO)점수는 평균 9.14 (SD = 2.55)로 나타나 다른 휴먼서비스 직군에 비해 평균이상의 직무스트레스를 가지고 있는 것으로 나타났다. 또한 자립생활센터 실무자들의 개인적 조직적 특성에 따른 직무스트레스 정도를 ANOVA LSD 사후검정을 통해 분석한 결과, RC지수는 실무자의 나이, 직무내용, 교육정도, 휴먼서비스 근무경력, 주당 근무시간에 따라 점수 차이를 보였고, RA지수는 실무자의 휴먼서비스 근무경력과 주당 근무시간에 따라, RO지수는 휴먼서비스 근무경력에 따라 그룹 간 차이를 보이는 것으로 나타났다. 마지막으로 자립생활센터 실무자들이 경험하는 직무스트레스와 소진간의 관계성을 알아보기 위해 회귀분석한 결과, 세 가지 직무스트레스 모두 소진의 예측변수로 나타났다.

• Korean Chemical Engineering Research
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• 제43권5호
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• pp.549-559
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• 2005

최근에 환경오염과 자원고갈에 의해서 인류활동의 생태적 영향을 최소화하는 지속 가능한 산업 개발(sustainable industrial development)이 많은 관심을 받고 있다. 이를 위해서는 기존에 있던 산업단지를 환경친화적으로 변화시키거나 새로운 산업단지를 건설하여 개별 공장 내뿐만 아니라 한 산업단지 내의 각 기업들이 물질 및 에너지를 최대한 효율적으로 이용하는 생태산업단지로의 전환이 전 세계적으로 활발하게 이루어지고 있다. 생태산업단지(eco-industrial park, EIP)는 산업단지 내의 각 기업들이 물질, 용수 및 에너지를 최대한 폐기물, 에너지, 물질, 용수 등을 서로 효율적으로 재이용함으로써 경제, 환경, 사회적 이익을 얻는 것을 목표로 한다. 본 총설에서는 국내외 생태산업단지의 사례연구와 생태산업단지 개발의 중요한 기술들(에너지 교환, 물질 재이용, 용수 재이용, 환경영향평가)에 대하여 소개한다.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 2002년도 학술대회지
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• pp.55-65
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• 2002

Ginseng has been used as a key constituent in traditional medicine prescriptions for centuries. Other than its well-known anti-stress and adaptogenic properties, ginseng has also been shown to be very effective in treating age-related deterioration in metabolic and memory functions. Although it is generally believed that the saponin (GS) fraction of the ginseng root accounts for the bioactivity of ginseng, a direct demonstration on which ginsenoside does what is still generally lacking. In the past decade, our laboratory has endeavored to identify the active GS components involved in energy metabolism, memory, and anti-neurotoxicity. To examine the ergogenic effects of GS in enhancing aerobic capacity, rats were subjected to either severe cold ($40^{\circ}C$ under helium-oxygen, two hours) or exercise workload $(70\%\;VO_{2}max,$ to exhaustion). Acute systemic injection (i.p.) of ginseng GS (5-20 mg/kg) significantly elevated both the total and maximum heat production in rats and improved their cold tolerance. However, pretreating the animal with the optimal dose (10 mg/kg) of GS devoid of $Rg_1\;and\;Rb_1$ failed to elicit any beneficial effects in improving cold tolerance. This indicates that either $Rb_1\;and/or\;Rg_1$ may be essential in exemplifying the thermogenic effect of GS. Further studies showed that only pretreating the animals with $Rb_1(2.5-5\;mg/kg),\;but\;not\;Rg_l,$ resulted in an increase in thermogenesis and cold tolerance. In contrast to the acute effect of GS on cold tolerance, enhancement of exercise performance in rats was only observed after chronic treatment (4 days). Further, we were able to demonstrate that both $Rb_1\;and\;Rg_1$ are effective in enhancing aerobic endurance by exercise. To illustrate the beneficial effects of GS in learning and memory, a passive avoidance paradigm (shock prod) was used. Our results indicated that the scopolamineinduced amnesia can be significantly reversed by chronically treating (4 days) the rats with either $Rb_1\;or\;Rg_1$ (1.25 - 2.5 mg/kg). To further examine its underlying mechanisms, the effects of various GS on ${\beta}-amyloid-modulated$ acetylcholine (ACh) release from the hippocampal slices were examined. It was found that inclusion of $Rb_1$ (0.1 ${\mu}M$), but not $Rg_1$, can attenuate ${\beta}-amyloid-suppressed$ ACh release from the hippocampal slices. Our results demonstrated that $Rb_1\;and\;Rg_1$ are the key components involved in various beneficial effects of GS but they may elicit their effects through different mechanisms.

• 대한조선학회논문집
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• 제53권6호
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• pp.503-513
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• 2016

In order to reduce the green-house gas exhaustion, International Maritime Organization (IMO) has been reinforcing carbon gas regulations. Due to the regulations, a lot of competitions for designing Eco ship in the shipbuilding industry are progressing now. It is faced with the necessity of reducing hull weight by combining automated systems for optimal compartment arrangement with hull structural design. Most researches on optimum structural design method have been consistently in progress and applied to minimize weight and cost of mid-ship section in preliminary ship design stage based on analytical structural analysis method on fixed compartment arrangement. In order to reduce design period and to improve international technical competitiveness by shortening the period of hull structural design and enhancing design accuracy, it has been felt necessity to combine optimized compartment arrangement with optimum design of ship structure based on the international regulations and rules. So in this study, the automated design algorithm for longitudinal members has been developed to combine automated algorithm of compartment arrangement with hull structural design system for oil tanker. The SeaTrust-Hullscan software developed by Korean Register is used to perform ship structural design for mother ship and selected design cases. The effect of weight reduction is verified with comparison of ship weight between mother ship and the cases suggested in this study.

• 한국콘텐츠학회논문지
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• 제19권4호
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• pp.621-637
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• 2019

본 연구에서는 온라인쇼핑몰 콜센터 상담사의 감정노동이 고객지향성에 미치는 영향을 검증하고 직무소진의 매개효과를 검증하였다. 연구대상은 온라인쇼핑몰을 운영하는 4개 회사의 콜센터 상담사를 대상으로 하였으며 271부를 최종 자료 분석에 사용하였고 연구결과는 다음과 같다. 첫째, 감정노동의 하위요소인 내면행동은 고객지향성에 유의미한 정(+)의 영향을 주는 것으로 나타났다. 둘째, 감정노동의 내면행동은 비인격화와 개인성취감 저하에 부(-)의 영향을 주는 것으로 나타났으며, 표면행동은 감정고갈과 비인격화에 정(+)의 영향을 주는 것으로 나타났다. 셋째, 감정노동의 내면행동은 직무소진의 하위요인인 비인격화와 개인성취감 저하를 경유하여 고객지향성을 높이는 것으로 나타났으며 표면행동은 비인격화에 의해 매개되어 고객지향성을 낮추는 것으로 나타났다. 본 연구의 결과를 통해 고객지향성의 제고를 위해서는 내면행동은 높이고 직무소진을 낮출 필요가 있음을 확인하였다. 또한 직무소진의 역할과 매개효과를 검증하였다는 데에 그 의의가 있다.

• 한국콘텐츠학회논문지
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• 제19권7호
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• pp.538-545
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• 2019

본 연구는 노년기 지연성 근육통증에 대해 가우스 자기장 영역별 적용을 통해 체열 변화와 통증척도를 분석하고자 하였다. 이에 노년기 여성 15명(연령;$69.47{\pm}1.60$)을 대상으로 선정하여 반복측정을 통한 실험에 임하였다. 가우스 자기장 영역을 3범위(1000G, 1500G, 2000G) 영역으로 나누어 임의 제작한 자기장 손목밴드 적용하여 착용전과 후에 나타나는 체열변화와 통증 결과를 SPSS 19.0을 이용하여 정리하였다. 치료 영역별 전-후 차이검증을 위해서 종속 t검증(Paired t-test)과 집단 간 차이와 상호작용 효과 차이검증을 위해 two-way ANOVA을 실시하였고 사후검증(Duncan)을 통해 분석하였다. 유의 수준은 ${\alpha}=.05$로 설정 하였다. 이상의 도출된 결과는 다음과 같다. 가우스 자기장 영역별 전-후 체열 변화는 세 집단 모두 유의한 차이를 보였다(P<.05). 집단 간 상호 작용의 결과에서도 유의한 차이를 보였다(P<.05). 지연성 근육 통증척도에서도 시기 간-집단 간 모두 유의한 차이를 보였다. 가장 큰 차이를 보인 영역은 1500G 영역에서 나타났다. 1000G - 1500G 가우스 영역이 체열과 근육통증 변화에 가장 이상적인 자기장 영역이라 판단된다. 결론적으로 가우스 자기장 1000G-1500G영역이 노년기 신체 체열과 근육통증에 영향을 줄 수 있으며 노년기 인간 삶의 질에 큰 영향을 미칠 것으로 사료된다. 추후 연구에서는 가우스 자기장 효과를 인체 세포의 생리학적 측면에서의 연구가 필요하다고 사료된다.

• 한국가족복지학
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• 제55호
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• pp.59-90
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• 2017

본 연구는 소아암 환아와 가족을 위해 한국백혈병소아암협회에서 실시된 '가족희망파트너사업' 의 총체적인 효과를 규명하고 이들에 대한 지원의 실증적 기초자료를 마련하는데 그 목적이있다. 이를 위해 본 연구는 '가족희망파트너사업'을 통해 1년 이상 서비스를 이용 중인 보호자6명, 소아암 아동 5명을 2016년 6~7월까지 인터뷰하였으며, 수집된 자료는 질적분석 과정을거쳐 해석되었다. 본 연구의 결과는 다음과 같다. 소아암 환아와 가족은 '혹독한 아픔의 장벽' 과 '소용돌이치는 불안과 소진'에 직면해있었는데, '가족희망파트너사업'을 통해 연계된 '회복과 성장의 디딤돌이 되어준 참 스승'으로 말미암아 다차원적인 효과를 경험하게 되었다. 즉'환아의 전반적인 재활 지원', '가족관계의 향상', '사회적 관계에 대한 해갈(解渴)', '압박에서의 해방'이라는 긍정적인 효과들을 체험하게 되었다. 본 연구는 '가족희망파트너사업'의 다차원적인 효과를 심층적으로 확증하였으며, 한국백혈병소아암협회에 의해서 소아암 환아와 가족을 위해 국내외적으로 최초로 시도된 '가족희망파트너사업'의 방향성을 모색하였다는데 의의가있다.

• Journal of Ginseng Research
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• 제43권4호
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• pp.580-588
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• 2019

Background: Ginsenoside Rg1 has been shown to clear senescence-associated beta-galactosidase (SA-${\beta}$-gal) in cultured cells. It remains unknown whether Rg1 can influence SA-${\beta}$-gal in exercising human skeletal muscle. Methods: To examine SA-${\beta}$-gal change, 12 young men (age $21{\pm}0.2years$) were enrolled in a randomized double-blind placebo controlled crossover study, under two occasions: placebo (PLA) and Rg1 (5 mg) supplementations 1 h prior to a high-intensity cycling (70% $VO_{2max}$). Muscle samples were collected by multiple biopsies before and after cycling exercise (0 h and 3 h). To avoid potential effect of muscle biopsy on performance assessment, cycling time to exhaustion test (80% $VO_{2max}$) was conducted on another 12 participants (age $23{\pm}0.5years$) with the same experimental design. Results: No changes of SA-${\beta}$-gal were observed after cycling in the PLA trial. On the contrary, nine of the 12 participants showed complete elimination of SA-${\beta}$-gal in exercised muscle after cycling in the Rg1 trial (p < 0.05). Increases in apoptotic DNA fragmentation (PLA: +87% vs. Rg1: +133%, p < 0.05) and $CD68^+$ (PLA:+78% vs. Rg1:+121%, p = 0.17) occurred immediately after cycling in both trials. During the 3-h recovery, reverses in apoptotic nuclei content (PLA:+5% vs. Rg1 -32%, p < 0.01) and increases in inducible nitrate oxide synthase and interleukin 6 mRNA levels of exercised muscle were observed only in the Rg1 trial (p < 0.01). Conclusion: Rg1 supplementation effectively eliminates senescent cells in exercising human skeletal muscle and improves high-intensity endurance performance.