• The Journal of Korean Physical Therapy
• /
• 제14권4호
• /
• pp.100-118
• /
• 2002

This study was to investigate the effect of long-term high intensity endurance training on the activation of antioxidation enzyme activity, lipid peroxidation and lipoprotein metabolism. 15 subjects were divided into, endurance exercise + antioxidation Vitamin supplement(n=5), endurance exercise(n=5), and the control(n=5) groups. The endurance exercise groups(endurance exercise + antioxidation Vitamin supplement and endurance exercise) had 12 week of endurance exercise program. The antioxidation Vitamin supplement group was taken a Vitamin C tablet with 1000mg/day and Vitamin E tablet with 671.14mg/day right after lunch. The results obtained from this study were as follows; 1. Looking at the changes of SOD, Endurance exercise+antioxidation Vitamin supplement group and endurance exercise groups showed the significantly greater decrease in the activation of SOD after 12 weeks of all-out exercise. 2. Looking at the changes of CAT, Endurance exercise+antioxidation Vitamin supplement group revealed subjects tended to increase CAT after all-out exercise although statistically non-significant. Endurance exercise+antioxidation Vitamin supplement group showed the significantly greater increase in the activation of CAT after 12 weeks treatment for all-out exercise. 3. Looking at the changes of GPX, Endurance exercise+antioxidation Vitamin supplement group revealed subjects tended to increase GPX for the rest and after all-out exercise although statistically non-significant. Endurance exercise+antioxidation Vitamin supplement group showed the significantly greater increase in the activation of GPX after 12 weeks treatment for all-out exercise. 4. The MDA change showed the significant decrease after 6 weeks, after 12 weeks for the all-out exercise of Endurance exercise + antioxidation Vitamin supplement group. 5. There was non-significant change in lipoprotein metabolism for the rest and after all-out exercise.

• 대한물리의학회지
• /
• 제13권2호
• /
• pp.157-165
• /
• 2018

PURPOSE: The purpose of this study was carried out to investigate the effect of plyometric training combined with core strength training on the balance and agility of adolescent soccer players. METHODS: A total of 36 subjects participated in this study. Subjects were randomly divided 3 groups and assigned PG (plyometric training group), CSG (core strength training group) and PCG (plyometric training combined with core strength training group). Each group was assigned to 12. Intervention was performed three times a week for 4 weeks. The training was performed for 60 minutes a day. Subjects were warmed up for 10 minutes, and performed main exercise for 40 minutes. Finally, subjects performed cool-down exercise including stretching for 10 minutes. A Statistical analysis was performed the paired t-test for the comparison pre and post intervention. A comparison among the groups was using one-way ANOVA, and the LSD was used for the post-test. RESULTS: The balance and agility were statistically significant differences in all group (p<.05). There was no significant difference in the balance factors between the three groups, but there was a significant difference in the agility factor (p<.05). CONCLUSION: Plyometric training and plyometric training combined with core strength training were effective for the balance and agility of adolescent soccer players.

• Journal of Nutrition and Health
• /
• 제29권8호
• /
• pp.881-888
• /
• 1996

The purpose of this study was to determine whether vitamin B6(B6) deficiency affects fuel utilization and blood cholesterol profile with exercise-training. Twenty-four rats were fed a B6 deficient(-B6) diet or a control (+B6) diet for 5 weeks and either exercised(EX) or nonexercised (NE). EX rats were exercised on treadmill(10$^{\circ}$, 0.5-0.8km/h) for 20 minutes everyday. Glucose(GLU), glycogen (GLY), protein(PRO), trglyceride(TG), free fatty acid(FFA), total cholesterl(TC), HDL-cholesterol(HDL-C) and LDL-choleterol(LDL-C) were compared in plasma(P), liver(L) and skeletal muscle(M) of rats. There was a vitamin effect on the level of P-GLU, P-TG, M-TG, L-GLY, L-PRO and an exercise effect on the level of P-PRO, P-FFA, M-PRO, L-GLY, L-TG, P-TC, P-HDL-C, P-LDL-C. Compared to +B6 rats were lower and there were no differences in P-GLU, P-FFA, P-TG. M-GLY, L-TG, P-TC and P-HDL-C. In EX group, the level of P-TG was higher and M-PRO was lower in -B6 rats. There were no differences in M-GLY, L-TG, P-TC and P-HDL-C. These results suggest that a lowered intake of vitamin B6 may impair the adaptation of animals to fuel metabolism related to a decrease of fatty acid oxidation and attenuates the exercise-traning effect on blood lipid profile.

• Physical Therapy Rehabilitation Science
• /
• 제10권3호
• /
• pp.263-269
• /
• 2021

Objective: The purpose of this study was to examine the effects lumbar stabilization exercise with kinesio taping on pain, muscle strength, and oswestry disability index (ODI) in patients with chronic low back pain. Design: Two groups pre-post randomized controlled design Methods: Thirty-two subjects were randomly divided in two groups; 1) lumbar stabilization exercise with kinesio taping group (Experimental group, n=16), 2) lumbar stabilization exercise with sham kinesio taping group (Control group, n=16). The intervention was conducted in each group for thirty minutes a day, 5 times a week, for 4 weeks. Both group did 30 minutes of lumbar stabilization application. Evaluations were performed before the commencement of training and again 4 weeks after training was initiated. Visual analog scale (VAS) was used to evaluate pain level of patients with chronic low back pain. Distal muscle test was used to evaluate muscle strength of trunk extension. In addition, ODI was used to evaluate activity daily life of low back pain. Results: After training, the VAS, muscle strength of trunk extension and ODI were significantly more improvement in Experimental group than in the control group (p<0.05). Conclusions: We confirmed that the effects of lumbar stabilization exercise with kinesio taping group on pain, muscle strength, and ODI in patients with chronic low back pain.

• The Korean Journal of Physiology and Pharmacology
• /
• 제26권3호
• /
• pp.207-218
• /
• 2022

Aging in mammals, including humans, is accompanied by loss of bone and muscular function and mass, characterized by osteoporosis and sarcopenia. Although resistance exercise training (RET) is considered an effective intervention, its effect is blunted in some elderly individuals. Fibroblast growth factor (FGF) and its receptor, FGFR, can modulate bone and muscle quality during aging and physical performance. To elucidate this possibility, the FGFR inhibitor NVP-BGJ398 was administrated to C57BL/6n mice for 8 weeks with or without RET. Treatment with NVPBGJ398 decreased grip strength, muscular endurance, running capacity and bone quality in the mice. FGFR inhibition elevated bone resorption and relevant gene expression, indicating altered bone formation and resorption. RET attenuated tibial bone resorption, accompanied by changes in the expression of relevant genes. However, RET did not overcome the detrimental effect of NVP-BGJ398 on muscular function. Taken together, these findings provide evidence that FGFR signaling may have a potential role in the maintenance of physical performance and quality of bone and muscles.

• 동의생리병리학회지
• /
• 제20권5호
• /
• pp.1211-1216
• /
• 2006

The effect of a chronic programme of either low- or moderate-to-high-intensity treadmill running on the activation of the Extracellular-signal regulated protein kinase (ERK1/2), Phosphorylated ERK 1/2(pERK1/2) and the Phosphorylated c-Jun N-terminal kinase(pJNK) pathways was determined in rat Back skin Hair follicle. Sprague-Dawley rats were assigned to one of three groups: (i) sedentary group(NE; n=10); (ii) low-intensity exercise group (Bm/min; LIE; n=10); and (iii) moderate-high-intensity exercise group(28m1min; HIE; n=10). The training regimens were planned so that animals covered the same distance and had similar utilization for both LIE and HIE exercise sessions. The report runs as follows; A single bout of LIE or HIE following 4 weeks of exercise led to a twofold increase in the phosphorylation of ERK2, pERK2 and a threefold increase in pJNKl, pERKl. ERKI phosphorylation in LIE Back skin sampled and pJNK2 in HIE Back skin sampled 48h after the last exercise bout was similar to sedentary values, while pJNK2 phosphorylation in LIE Back skin sampled was 70-80% lower than sedentary. 48h after the last exercise bout of LIE or HIE increased ERK2, pERKl and pJNKl expression, with the magnitude of this increase being independent of prior exercise intensity or duration. PERK1/2, pJNKl expression was increased Three- to fourfold in Back skin Hair follicle sampled 48h after the last exercise bout irrespective of the prior exercise programme, but ERKI expression in HIE Back skin sampled was approximately 90% lower than sedentary values. In conclusion, exercise-training of different jntensities/durations results in selective postexercise activation of intracellular signal pathways, which may be one mechanism regulating specific adaptations induced by diverse training programmes.

• 한국산학기술학회논문지
• /
• 제19권1호
• /
• pp.179-187
• /
• 2018

본 연구는 운동선수의 지도행동유형이 선수만족 및 운동몰입과의 관계를 규명하여 선수의 능력을 향상시켜서 경기력을 높이는데 목적이 있다. 표집방법으로 비확률표본추출법을 이용하였고, 설문지의 총 381부를 자료 분석에 사용하였다. 설문지는 SPSS/PC+ Window용 21.0 version 통계프로그램을 이용하여, 연구 대상자의 빈도 분석과 요인분석, 상관관계 분석, 다중회귀분석을 실시하였다. 본 연구의 결과는 첫째, 운동선수의 지도행동유형인 훈련과 지도행동, 민주적 행동, 긍정적 피드백, 사회적지지에서 선수만족 및 운동몰입에서 상호관련성은 정적(+)인 상관관계가 나타났으며, 지도행동유형의 권위적 행동에서는 운동몰입에 상관관계가 나타나지 않았다. 둘째, 운동선수의 지도행동유형이 선수만족에 대한 결과는 사회적 상호작용은 훈련과 지도, 사회적 지지에서, 과제 수행은 훈련과 지도에서, 코치의 지도성은 훈련과 지도, 긍정적피드백에서 정적인 영향을 미치는 것으로 나타났다. 셋째, 운동선수의 지도행동유형이 운동몰입에 대한 결과는 인지몰입은 훈련과 지도, 긍정적 피드백에서, 행위몰입은 훈련과 지도, 긍정적 피드백, 사회적 지지에서 정적인 영향을 미치는 것으로 나타났다. 따라서 선수들의 운동수행만족과 운동에 몰입하여 경기에 임하게 된다면 좋은 운동기술수행을 통하여 최상의 경기력을 발휘할 수 있을 것이다.

• Journal of Nutrition and Health
• /
• 제34권8호
• /
• pp.872-880
• /
• 2001

The purpose of this study was to investigate the effects of glucuronic acid on antioxidative defense system and recovery of muscle fatigue in rat artier aerobic exercise. Sprague-Dawley male rats weighing 150 $\pm$ 10g were randomly assigned to one normal(N) group and three exercise training groups. Exercise training groups were classified into glucuronic acid free intubation group(T group), 250mg glucuronic acid/kg bw intubation group(TU group), and 500 mg glucuronic acid/kg bw intubation group(2TU group) according to glucuronic acid supplementation level. The glucuronic acids were administered to rats by oral intubation before exercise training. The experimental rats in exercise training groups(T, TU and 2TU) were exercised on glucuronic acid supplementation or rats in normal group were confined in cage for 4 weeks. And rats were sacrificed with an overdose of pentobarbital injection just after running. Liver xanthine oxidase(XOD) activities were not significantly different among four groups. The activity of superoxide dismutase(SOD) in T group was no significant difference from N group, but those of TU and 2TU groups were increased by 9% and 18%, respectively, compared with that of T group. Liver glutathione peroxidase(GSHpx) activites of T and TU groups showed a similar tendency to that of normal group, but increase 17% in 2TU group compared with normal group. The ratio of GSH/GSSG in liver of T group was lower than that of normal group, but those of TU and 2TU groups were a similar tendency to that of normal group. Contents of thiobarbituric acid reactive substance(TBARS) in T group was increased by 47%, compared with that of normal group but those of TU group and 2TU group were lower 27% and 35%, respectively, compared with that of T group. The contents of glycogen in soleus muscle significantly lower in all three trained exercise groups than that of normal group, but there were no significant differences among the trained exercise groups. Contents of hepatic glycogen in T group were decreased 27% compared with those of normal group while those of TU and 2TU groups were the same as normal group levels. The contents of serum lactic acid in T group were increased 240% of normal group, but hose of TU and 2TU groups were decreased 38%, 39%, respectively, by glucuronic acid supplementations, compared with that of T group. In conclusion, the effects of glucuronic acids in exercise training rats would appear to reduce peroxidation of tissue as an antioxidative defense mechanism and promote recovery of muscle fatigue.

• 한국식품영양과학회지
• /
• 제42권10호
• /
• pp.1585-1591
• /
• 2013

본 연구의 목적은 고지방식으로 유도된 비만이 에너지 항상성 조절인자인 신경영양인자와 섭식조절 호르몬인 렙틴 mRNA 발현에 어떠한 관련성이 있는지를 규명하는 것과 비만 쥐의 시상하부 BDNF 발현과 렙틴 리셉터 mRNA 발현, 혈청 렙틴과 항비만과의 관계에 대한 운동트레이닝과 정상식이로의 전환에 대한 효과를 확인하고자 하였다. 그 결과 8주 후 비만 대조군(HF)에 비해 운동군(HFT), 정상식이군(HFND), 운동 및 정상식이 트레이닝군(HFNDT)에서 각각 유의한 체중 및 혈중 TC 감소를 보였다(P<0.05). 혈중 TG에서는 HF군에 비해 HFNDT군에서 유의한 감소를 보였다(P<0.05). 혈중 렙틴은 HF군에 비해 HFT군에서 유의한 감소를(P<0.05), HFT군에 비해 HFND군에서 유의한 감소를 보였으며(P<0.05), HFND군에 비해 HFNDT군에서 유의한 감소를 나타냈다(P<0.05). 시상하부 BDNF 단백질 발현은 HF군에 비해 모든 군에서 유의한 증가를 보였다(P<0.05). 시상하부 렙틴 리셉터 mRNA는 HF군에 비해 HFT와 HFND군에서 약간의 감소를, HFNDT군에서는 증가를 나타내었다. 이상의 결과는 고지방식이로 유도된 비만쥐에 대한 운동트레이닝은 항비만 효과가 있는 것으로 나타났으며, 운동 또는 정상식이의 병행은 식욕과 체중조절에 최적의 비만예방 및 개선효과가 있을 것으로 사료된다.

• 생명과학회지
• /
• 제22권5호
• /
• pp.665-670
• /
• 2012

이 연구는 자연발생고혈압쥐(SHR)의 혈압, 골격근에서의 혈관생성 및 혈관내피세포성장인자 발현(VEGF)에 미치는 지구성운동의 효과를 조사하였다. 5주령 SHR와 WKY는 무작위로 정상혈압군(WKY, Wistar-Kyoto rat, n=9), 고혈압통제군(SHR-C, SHR Control, n=9) 및 고혈압운동군(SHR-E, SHR Exercise, n=9)으로 각각 분류하였고, 지구성운동은 트레드밀을 이용하였다(12-20 m/min, 0% grade, 60 min/day, 5 days/wk, 16 wk). 수축기혈압은 지구성운동에 의해 효과적으로 감소되었다(SHR-E vs. SHR-C, $p$ <0.05). 골격근의 모세혈관밀도와 VEGF 단백발현은 고혈압통제군(SHR-C)이 정상혈압군(WKY)보다 모두 감소되었으나, 지구성운동(SHR-E)이 고혈압통제군(SHR-C)에 비해 모두 증가되었다. 이러한 결과들은 지구력운동 트레이닝이 SHR 골격근의 VEGF 단백발현의 증가를 통해 모세혈관밀도를 향상시키고, 이러한 모세혈관밀도의 향상이 SHR의 혈압상승을 억제할 수 있다는 것을 의미한다.