• Title/Summary/Keyword: Excellence Education

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Calcium Sensing Receptor Modulation for Cancer Therapy

  • Sarkar, Puja;Kumar, Sudhir
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3561-3568
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    • 2012
  • The calcium sensing receptor (CaSR) is a member of the largest family of cell surface receptors, the G protein-coupled receptors involved in calcium homeostasis. The role of the CaSR in neoplasia appears to be homeostatic; loss of normal CaSR-induced response to extracellular calcium is observed in cancers of the colon and ovary, while increased release of PTHrP is observed in cancers of the breast, prostate and Leydig cells. Currently CaSR can be considered as a molecule that can either promote or prevent tumor growth depending on the type of cancer. Therefore, recognition of the multifaceted role of CaSR in gliomas and other malignant tumors in general is fundamental to elucidating the mechanisms of tumor progression and the development of novel therapeutic agents. Emphasis should be placed on development of drug-targeting methods to modulate CaSR activity in cancer cells.

Snake Venom: A Potent Anticancer Agent

  • Jain, Deepika;Kumar, Sudhir
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.4855-4860
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    • 2012
  • Since cancer is one of the leading causes of death worldwide, and there is an urgent need to find better treatment. In recent years remarkable progress has been made towards the understanding of proposed hallmarks of cancer development and treatment. Treatment modalities comprise radiation therapy, surgery, chemotherapy, immunotherapy and hormonal therapy. Currently, the use of chemotherapeutics remains the predominant option for clinical control. However, one of the major problems with successful cancer therapy using chemotherapeutics is that patients often do not respond or eventually develop resistance after initial treatment. This has led to the increased use of anticancer drugs developed from natural resources. The biodiversity of venoms and toxins makes them a unique source from which novel therapeutics may be developed. In this review, the anticancer potential of snake venom is discussed. Some of the included molecules are under clinical trial and may find application for anticancer drug development in the near future.

Towards a "better" University: the Use of the EFQM Model in a UK Higher Education Institution

  • Blackmore, Jacqueline;Douglas, Alex
    • International Journal of Quality Innovation
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    • v.4 no.2
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    • pp.1-15
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    • 2003
  • This paper examines the use of the EFQM Model in H.E. Institutions in the UK and offers a case study of how one University used the Excellence Model as a means to change the way it operated. It identifies and discusses the critical success factors for a university utilizing the Model, in particular Leadership (criteria 1), People Management, particularly with regard to performance evaluation (criteria 3), having key processes in place (criteria 5) and the identification of the correct key performance results for its various stakeholders (criteria 9).

Analysis of the Contents of Hanbok in the 「Home Life and Safety」 section of the High School Technical Family Textbook: Content Analysis and Text Mining Techniques are utilized (고등학교 기술·가정 교과서 「가정생활과 안전」 영역의 한복 내용 분석)

  • Shim, Joon Young;Baek, Min Kyung
    • Human Ecology Research
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    • v.59 no.2
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    • pp.261-273
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    • 2021
  • This study is not just a meaning of costume but a function of culture and includes addresses the associated emotions. As the interest of youths has increased recently, the importance of traditional costume education has been growing. Therefore, this study aims to analyze the contents of Hanbok in the 2015 revised high school technology and home textbooks using content analysis techniques and text mining techniques. As a result of the study, first, the symbolic meaning and characteristics of Hanbok and the beauty of Hanbok were practiced in daily life, and the value was found through the excellence of Hanbok and the modernization of Hanbok was dealt with Second, most of the illustrations related to traditional costumes were presented in various ways, but there were some regrets due to lack of quantity and quality. Third, the words used to explain traditional costumes were used in the form of culture, excellence, tradition, modernity, harmony, succession, etc. except for the types of clothing. Therefore, the results and discussions derived from this study are expected to help the textbooks to be efficiently selected and used in the field of the front line school along with the correct understanding of traditional culture in the process of selecting traditional culture contents and illustrations.

Realization of VR-linked "Wearing a Mask" SW training to recognize the effect of wearing a mask due to the spread of new infectious diseases (신종 감염병 확산에 따른 마스크 착용효과 인지를 위한 VR연동 "Wearing a Mask" SW교육 제안)

  • Seo, Hee-Cheol;Park, Yu-Min;Cho, Young-Ju
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2020.07a
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    • pp.625-628
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    • 2020
  • 현재 지구촌은 신종 감염병인 '코로나바이러스 감염증-19(COVID-19)로 인해 혼란을 겪고 있다. 우리나라의 경우 1만 명 이상 감염자가 발생하였으며, 사망자 역시 200여 명이 넘었다. 하지만 위와 같은 감염병을 치료하기 위한 백신은 계속 개발중에 있으며, 현재는 감염 예방 수칙으로 감염의 위험성에서 벗어나고 있는 실정이다. 또, 지구촌에 큰 혼란을 주었던 사스, 신종플루, 메르스와 같이 주로 호흡기를 통해 타인에게 전파되는 신종 감염병 출현 빈도 역시 계속 증가하고 있다. 이외에는 황사, 미세먼지에 관한 문제들로 인해 일상속에서 이뤄지는 생활 방역의 중요성이 대두되고 있는 상황이다. 본 논문에서는 생활 방역의 대표적 수칙인 마스크 착용에서 상황별 올바른 마스크 선택의 중요성을 알려주어 시민의식을 높일 수 있는 VR 연동 'Wearing a Mask' 구현에 대해 제안하고자 한다.

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Development of Elementary School Curriculum Relating to Robot Programming for Excellence Education and its Application (수월성 교육을 위한 초등학교 로봇프로그래밍 교육과정 개발과 적용)

  • Yoo, Seoung-Han;Moon, Wae-Shik
    • Journal of The Korean Association of Information Education
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    • v.11 no.1
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    • pp.59-66
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    • 2007
  • This study is aimed at developing a curriculum in relation to programming learning by using robot, for it has been judged as a scientific learning tool to help elementary school children as well as gifted children among them improve their creativity. Based on this concept, teaching aids and materials were developed, and then applied to the locale of education, and results therefrom were analyzed ccordingly. Curriculum and contents of teaching aids were classified into two processes, i.e. the assembling process of robot to fit the varied problematic situations and the programming process (all six phases), and edited so much as to entice elementary school children to get interests and attentions to robot and programming by compiling the contents to suit their level of learning. Results from the evaluation of the application of robot education curriculum to the locale for learning revealed that it was a positive teaching tool that helped children improve their creativity. Also conclusions were derived from the analysis and evaluation that several aspects should be complemented as for teaching and learning tool to achieve the objective of excellence education.

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Curriculum Redesign for Excellence in Medical Education (의학교육 수월성 제고를 위한 교육과정 재설계)

  • Yang, Eunbae B.
    • Korean Medical Education Review
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    • v.16 no.3
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    • pp.126-131
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    • 2014
  • The purpose of this study is to analyze the medical education system of Korea and to propose a method of curriculum redesign. Although there have been many attempts by medical educators to improve the quality of medical education, the results have not been fruitful. First, there exists a limitation to the dualistic curriculum design based on Flexnerianism, and thus, this model does not provide an integrated experience to medical students. Therefore, we propose a unidimensional model for curriculum redesign. Second, it is impossible to promote excellence in medical education without solving the structural problems of teaching and learning, such as the teaching competency of the faculty, large-scale lectures, and team teaching systems. A curricular strategy that emphasizes mutual interaction and teaching accountability is necessary to promote meaningful learning. Third, the current clinical training system, the circulation model, provides incomplete training as well as a lack of sequence and articulation experiences. This system needs to be redesigned in a way that allows only those students who have mastered both the knowledge and the application of medical education to advance to the next step. Fourth, norm-referenced assessments of a medical college distort the learning process and create unconstructive system energy. A criterion-referenced assessment that values cooperation, independent study, and intrinsic motivation is more important for the reliability and validity of the assessment. Medical students should not focus on formative and informative learning. Medical colleges should investigate the multifaceted potential of the students and provide transformative learning to grow students into change agents. For this to take place, curriculum redesign-not new methods of medical education-is required.