• 제목/요약/키워드: Evolution Ratio

검색결과 488건 처리시간 0.028초

교반형 막 반응기를 이용한 재조합 인간 세포의 무혈청 배지에 의한 $\gamma$-Interferon의 생산 (Economic Production of $\gamma$-Interferon from Recombinant Human Cells in Serum Free Medium by a Moving Aeration Membrane Bioreactor)

  • 박영식;김현규;임서규;박경유;이현용
    • 한국미생물·생명공학회지
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    • 제22권4호
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    • pp.389-394
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    • 1994
  • 8 X 10$^{6}$(viable cells/ml) of maximum cell density and 9000(IU/ml) of $\gamma$-IFN production were obtained at 55(ml/hr) of a perfusion rate by cultivating HSF cells using a moving membrane aeration bioreactor. This system proves to be an efficient culture process by maintaning 90% of viable cells during the whole cultivation periods. The metabolic molar quotient of glucose to lactate was 0.81 for overall ranges of glucose consumed while the evolution of ammonia was not linearly related to the consumption of glutamine. Low molar conversion ratio was observed in low consumptions of glutamine and high molar conversion ratio in high comsumptions. It also shows that the glutamolysis plays important role in the steady state conditions by evolving larger quantities of ammonia than lactate. At the above of 50 rpm, which is the optimum agitation speed for this bioreactor, the cell growth was severely affected while the IFN production was less decrea- sed, maintaing 1.5 X 10$^{-3}$(IU/cell/day) specific IFN production rate. The cumulatvie $\gamma$-IFN production was 7.2 X 10$^{8}$(IU) for 70 days of the cultivation, which yields 1 X 10$^{7}$ (IU/day) of IFN production rate. Therefore, a commercial production of $\gamma$-IFN by this culture process can be achievable by maintaining the above IFN productivity in a scaled-up culture system.

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잔류자화비를 이용한 운석의 자성광물 판별 (Magnetic Mineral Identification in Meteorites)

  • 김인호;유용재
    • 한국광물학회지
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    • 제24권1호
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    • pp.31-36
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    • 2011
  • 운석은 모암인 소행성(asteroid)이나 미세소행성(planetesimal)에서 충돌에 의해 분리된 후, 태양계 내의 공간을 배회하다가 지구의 중력에 이끌려 지표에 떨어진 후 수집된 돌덩이다. 따라서 생성 초기의 지구를 포함하는 태양계 내 지구형 행성의 생성 초기와 진화과정을 규명하려면 원시 태양계의 정보를 간직하고 있는 운석의 물리/화학적 분석이 반드시 필요하다. 특히 열잔류자화(thermoremanent magnetization, TRM) 대비 포화등온잔류자화(saturation isothermal remanent magnetization, SIRM)의 비율과 자화를 유도하는 자기장 강도의 상관관계를 이용하면 운석이 함유하는 자성광물을 판별할 수 있다. TRM/SIRM 비를 이용하여 2종류의 미분화운석(H5 Richardton, LL6 St. Severin)과 2종류의 화성기원 분화운석(ALH84001, DaG476)에 대해 자성광물 판별을 시도하였다. 실험 결과 H5 Richardton, LL6 St. Severin, ALH84001, DaG476의 주 자성광물이 각각 카마사이트, 테트라테나이트, 자철석, 크롬티탄함유철석임을 판별하였다.

Red AGNs becoming normal AGNs

  • Kim, Dohyeong;Im, Myungshin;Glikman, E.;Woo, Jong-Hak;Urrutia, T.
    • 천문학회보
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    • 제39권2호
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    • pp.57.2-57.2
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    • 2014
  • Red active galactic nuclei (AGNs) are supposed to be transitional objects becoming normal AGNs in the galaxy evolution scenario. So far, ~200 red AGNs have been found by very red color in optical through NIR wavelength (e.g., r'-K >5 and J-K>1.3; Urrutia et al. 2009). Here, we compare nuclear activities of the red AGNs to those of normal AGNs to verify the evolutionary phase of the red AGNs. In order to study the nuclear activities of the red AGNs, we use broad emission lines of $P{\beta}$ ($1.28{\mu}m$) of which flux is less suppressed by a factor of 100 than the $H{\beta}$ line in the case of the red AGNs with a color excess of E(B-V)=2 mag. We use 16 red AGNs discovered in previous red AGN surveys by using SDSS, 2MASS, and FIRST (Glikman et al. 2007; Urrutia et al. 2009) at z ~0.7 for which $P{\beta}$ lines are redshifted to the sky window at ${\sim}2.2{\mu}m$. The mean Eddington ratio of the 16 red AGNs is 0.562, and that of the normal AGNs is 0.320, which indicates the red AGNs include more active black hole (BH) than the normal AGNs. To test how significantly the nuclear activities of the red AGNs and the normal AGNs are different, we perform a two-dimensional Kolmogorov-Smirnov test (K-S test) on their Eddington ratio distributions. The K-S test shows the maximum deviation between the cumulative distributions, D, is 0.48, and the probability of null hypothesis, p, is even less than 0.001. This result is consistent with a picture of that the red AGNs are in intermediate phase between the stage of merger-driven starburst galaxy and the normal AGN.

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주기적으로 회전진동하는 원주 후류의 Dynamic PIV 속도장 측정 (Dynamic PIV Measurements of Wake behind a Rotationally Oscillating Circular Cylinder)

  • 이정엽;이상준
    • 한국가시화정보학회:학술대회논문집
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    • 한국가시화정보학회 2007년도 추계학술대회
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    • pp.134-137
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    • 2007
  • The temporal evolution of wake behind a circular cylinder oscillating rotationally with a relatively high forcing frequency has been investigated experimentally using a dynamic PIV technique. Experiments were carried out with varying the frequency ratio $F_R\;(=f_f/f_n)$ in the range from 0.0 (stationary) to 1.6 at oscillation amplitude of ${\theta}_A=30^{\circ}$ and Reynolds number of $Re=4.14{\times}10^3$. Depending on the forcing condition ($F_R$), the flow was divided into three regimes; non-lock-on ($F_R=0.4$), transition ($F_R=0.8$, 1.6) and lock-on regimes ($F_R=1.0$) with markedly different flow structure in the near-wake region behind the cylinder. When the frequency ratio was less than 1.0 ($F_R{\le}1.0$), the rotational oscillatory motion of the cylinder decreased the length of the vortex formation region and enhanced the mutual interaction between large-scale vortices across the wake centerline. The entrainment of ambient fluid seemed to play an important role in controlling the near-wake flow and shear-layer instability. However, the flow characteristics changed markedly beyond the lock-on flow regime ($F_R=1.0$) due to high-frequency forcing. At $F_R=1.6$, the mutual interactions between the vortices shed from both sides of the cylinder were not so strong. Thereby, the flow entrainment and momentum transfer into the wake center region were reduced. In addition, the size of the large-scale vortices decreased since the lateral extent of the wake was suppressed.

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한계 상태 기반 수정 Modified Cam Clay 파괴면 (Revision of Modified Cam Clay Failure Surface Based on the Critical State Theory)

  • 우상인
    • 한국지반공학회논문집
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    • 제36권4호
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    • pp.5-15
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    • 2020
  • 본 논문은 점성토의 응력-변형률 관계를 모사하기 위해 한계 상태 이론을 기반으로 하여 수정한 Modified Cam-Clay 파괴면을 제안한다. 평균유효응력과 von Mises 응력의 공간에서 타원형상의 파괴면을 가지는 Modified Cam-Clay 모델의 경우, 강성 및 발달법칙 미적용시, 비배수 전단조건하에 한계상태 평균유효응력은 선행압밀 평균유효응력의 절반이 되며, 이는 실제 점성토의 거동과 차이가 있다. 본 연구에서는 선행압밀 평균유효응력은 점성토의 압밀이력으로 정량화되고, 한계상태 평균유효응력은 점성토의 현재 간극비로 산정되어, 이 둘간의 비율이 고정되지 않는 찌그러진 형태의 파괴면을 제안한다. 제안된 파괴면을 항복평면으로 가정하고, 비배수 삼축압축 거동을 모사한 결과, 실내 실험 결과와 유사한 결과를 얻을 수 있었다

LTE/LTE-Advanced 시스템간 채널 간섭분석을 통한 주파수 공유 연구 (Study on the Spectrum Sharing based on Analysis of Channel Interference between LTE/LTE-Advanced Systems)

  • 강영흥
    • 한국항행학회논문지
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    • 제16권2호
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    • pp.219-226
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    • 2012
  • 3GPP의 LTE/LTE-Advanced 시스템은 OFDM(Orthogonal Frequency Division Multiplexing) 기술적용으로 주파수 할당에 의한 간섭분석 및 주파수 공유평가가 중요하다. 이에 본 논문에서는 LTE 두 사업자/시스템간의 인접채널 간섭 분석에 의한 주파수 공유연구를 수행하였다. 업링크 및 다운링크에서의 시스템 용량 및 스루풋(throughput) 손실에 대한 시뮬레이션 분석이 이루어져 5% 손실율의 주파수 공유기준으로 요구되는 ACIR(Adjacent Channel Interference Ratio) 값을 정의하였다. 유저(user)의 위치, 간섭 대역폭, 시스템 분리 옵셋(separation offset) 등의 파라미터들에 의해 주파수 공유를 위해 요구되는 ACIR 값에 미치는 영향이 분석되었으며, 이러한 결과 데이터 및 간섭분석 방법들은 향후 LTE RF 표준 및 주파수 유효이용에 참고자료로 활용될 것이다.

제조공정에 따른 MnO2산화물 전극의 전기화학적 특성 (Electrochemical Characteristics of MnO2 Electrodes as a function of Manufacturing Process)

  • 김현식;이해연;허정섭;이동윤
    • 한국전기전자재료학회논문지
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    • 제17권5호
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    • pp.486-491
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    • 2004
  • Dimensionally stable anode(DSA) can be used for the hydro-metallurgy of non-ferrous metals like as Zn, and the electrolysis of sea water. MnO$_2$ electrode satisfies the requirements of DSA, and has a good cycle life and a low overpotential for oxygen evolution. MnO$_2$ electrodes based on Ti matrix were prepared by using thermal decomposition method and also MnO$_2$ was coated on Ti and Pb matrix with DMF and PVDF compositions. The MnO$_2$ electrodes prepared by thermal decomposition method had very weak adhesive strength onto Ti matrix and MnO$_2$ layer was removed out so that electrochemical properties for MnO$_2$ were not investigated. The viscosity of solvent used as a binder of MnO$_2$ Powder increased with the increasing PVDF contents. The thickness of the MnO$_2$ layer on Pb matrix in DSA, which was prepared with 5 times dipping at the solution mixed with PVDF : DMF = 1 : 9, was 150${\mu}{\textrm}{m}$. When the ratio of PVDF to MnO$_2$ was lower than 1 : 6, the Pb electrode didn't show any reaction irrespective of the concentrations of DMF. However, When the ratio of PVDF to MnO$_2$ was higher than 1: 6, the Pb electrode showed constant current reactions and homogeneous cyclic voltammetry even though at a high cycle. The reason for the high current and homogeneous cyclic voltammetry is the good catalytic reactions of MnO$_2$ powder in electrode.

Unlimited Cooperative Sensing with Energy Detection for Cognitive Radio

  • Bae, Sunghwan;Kim, Hongseok
    • Journal of Communications and Networks
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    • 제16권2호
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    • pp.172-182
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    • 2014
  • In this paper, we investigate the fundamental performance limits of the cooperative sensing using energy detection by considering the unlimited number of sensing nodes. Although a lot of cognitive radio research so far proposed various uses of energy detection because of its simplicity, the performance limits of energy detection have not been studied when a large number of sensing nodes exist. First, we show that when the sensing nodes see the independent and identically distributed channel conditions, then as the number of sensing nodes N goes to infinity, the OR rule of hard decision achieves zero of false alarm Pf for any given target probability of detection $\bar{P_d}$ irrespective of the non-zero received primary user signal to noise ratio ${\gamma}$. Second, we show that under the same condition, when the AND rule of hard decision is used, there exists a lower bound of $P_f$. Interestingly, however, for given $\bar{P_d}$, $P_f$ goes to 1 as N goes to infinity. Third, we show that when the soft decision is used, there exists a way of achieving 100% utilization of secondary user, i.e., the sensing time overhead ratio goes to zero so does $P_f$.We verify our analyses by performing extensive simulations of the proposed unlimited cooperative sensing. Finally, we suggest a way of incorporating the unlimited cooperative sensing into a practical cellular system such as long term evolutionadvanced by exploiting the existing frame structure of absolute blank subframe to implement the in-band sensing.

Dual Bias Modulator for Envelope Tracking and Average Power Tracking Modes for CMOS Power Amplifier

  • Ham, Junghyun;Jung, Haeryun;Bae, Jongsuk;Lim, Wonseob;Hwang, Keum Cheol;Lee, Kang-Yoon;Park, Cheon-Seok;Yang, Youngoo
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제14권6호
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    • pp.802-809
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    • 2014
  • This paper presents a dual-mode bias modulator (BM) for complementary metal oxide semiconductor (CMOS) power amplifiers (PAs). The BM includes a hybrid buck converter and a normal buck converter for an envelope tracking (ET) mode for high output power and for an average power tracking (APT) mode for low output power, respectively. The dual-mode BM and CMOS PA are designed using a $0.18-{\mu}m$ CMOS process for the 1.75 GHz band. For the 16-QAM LTE signal with a peak-to-average power ratio of 7.3 dB and a bandwidth of 5 MHz, the PA with the ET mode exhibited a poweradded efficiency (PAE) of 39.2%, an EVM of 4.8%, a gain of 19.0 dB, and an adjacent channel leakage power ratio of -30 dBc at an average output power of 22 dBm, while the stand-alone PA has a PAE of 8% lower at the same condition. The PA with APT mode has a PAE of 21.3%, which is an improvement of 13.4% from that of the stand-alone PA at an output power of 13 dBm.

Fatigue behavior of concrete beams reinforced with HRBF500 steel bars

  • Li, Ke;Wang, Xin-Ling;Cao, Shuang-Yin;Chen, Qing-Ping
    • Structural Engineering and Mechanics
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    • 제53권2호
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    • pp.311-324
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    • 2015
  • The purpose of this study was to investigate experimentally the fatigue performance of reinforced concrete (RC) beams with hot-rolled ribbed fine-grained steel bars of yielding strength 500MPa (HRBF500). Three rectangular and three T-section RC beams with HRBF500 bars were constructed and tested under static and constant-amplitude cyclic loading. Prior to the application of repeated loading, all beams were initially cracked under static loading. The major test variables were the steel ratio, cross-sectional shape and stress range. The stress evolution of HRBF500 bars, the information about crack growth and the deflection developments of test beams were presented and analyzed. Rapid increases in deflections and tension steel stress occured in the early stages of fatigue loading, and were followed by a relatively stable period. Test results indicate that, the concrete beams reinforced with appropriate amount of HRBF500 bars can survive 2.5 million cycles of constant-amplitude cyclic loading with no apparent signs of damage, on condition that the initial extreme tensile stress in HRBF500 steel bars was controlled less than 150 MPa. It was also found that, the initial extreme tension steel stress, stress range, and steel ratio were the main factors that affected the fatigue properties of RC beams with HRBF500 bars, whose effects on fatigue properties were fully discussed in this paper, while the cross-sectional shape had no significant influence in fatigue properties. The results provide important guidance for the fatigue design of concrete beams reinforced with HRBF500 steel bars.