• Dementia and Neurocognitive Disorders
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• v.22 no.1
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• pp.1-15
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• 2023

The Seoul Neuropsychological Screening Battery (SNSB) is known as a representative comprehensive neuropsychological evaluation tool in Korea since its first standardization in 2003. It was the main neuropsychological evaluation tool in the Clinical Research Center for Dementia of South Korea, a large-scale multi-center cohort study in Korea that was started in 2005. Since then, it has been widely used by dementia clinicians, and further solidified its status as a representative dementia evaluation tool in Korea. Many research results related to the SNSB have been used as a basis for the diagnosis and evaluation of patients in various clinical settings, especially, in many areas of cognitive assessment, including dementia evaluation. The SNSB version that was updated in 2012 provides psychometrically improved norms and indicators through a model-based standardization procedure based on a theoretical probability distribution in the norm's development. By providing a score for each cognitive domain, it is easier to compare cognitive abilities between domains and to identify changes in cognitive domain functions over time. Through the development of the SNSB-Core, a short form composed of core tests, which also give a composite score was provided. The SNSB is a useful test battery that provides key information on the evaluation of early cognitive decline, analysis of cognitive decline patterns, judging the severity of dementia, and differential diagnosis of dementia. This review will provide a broad understanding of the SNSB by describing the test composition, contents of individual subtests, characteristics of standardization, analysis of the changed standard score, and related studies.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2023.05a
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• pp.289-290
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• 2023

According to relevant laws, in the case of a construction project with a total construction cost of 30 billion won or more, a post-construction evaluation must be performed after completion. In addition, a post-construction evaluation report must be prepared and entered into the Continuous Acquisition & Life-cycle Support(CALS). As a result of reviewing the currently accumulated post-construction evaluation reports, since the report is not standardized, it is difficult for public project owners to write the report. It also hinders the post-construction evaluation and management center from verifying contents, analyzing data, and deriving meaningful results. In order to improve the convenience of the public owners who must conduct post-construction evaluations and the work efficiency of the center, evaluation factors were standardized and a standard post-construction evaluation report format for road construction was developed in Excel. Through this, the data in the reports will be effectively accumulated, managed, and analyzed, so that meaningful results will be produced and be helpful in future construction work.

• Journal of Ginseng Research
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• v.45 no.1
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• pp.1-21
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• 2021

Panax species have gained numerous attentions because of their various biological effects on cardiovascular, kidney, reproductive diseases known for a long time. Recently, advanced analytical methods including thin layer chromatography, high-performance thin layer chromatography, gas chromatography, high-performance liquid chromatography, ultra-high performance liquid chromatography with tandem ultraviolet, diode array detector, evaporative light scattering detector, and mass detector, two-dimensional high-performance liquid chromatography, high speed counter-current chromatography, high speed centrifugal partition chromatography, micellar electrokinetic chromatography, high-performance anion-exchange chromatography, ambient ionization mass spectrometry, molecularly imprinted polymer, enzyme immunoassay, 1H-NMR, and infrared spectroscopy have been used to identify and evaluate chemical constituents in Panax species. Moreover, Soxhlet extraction, heat reflux extraction, ultrasonic extraction, solid phase extraction, microwave-assisted extraction, pressurized liquid extraction, enzyme-assisted extraction, acceleration solvent extraction, matrix solid phase dispersion extraction, and pulsed electric field are discussed. In this review, a total of 219 articles published from 1980 to 2018 are investigated. Panax species including P. notoginseng, P. quinquefolius, sand P. ginseng in the raw and processed forms from different parts, geographical origins, and growing times are studied. Furthermore, the potential biomarkers are screened through the previous articles. It is expected that the review can provide a fundamental for further studies.

• Journal of Ginseng Research
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• v.43 no.1
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• pp.116-124
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• 2019

Background: Ginsenosides are known as the principal pharmacological active constituents in Panax medicinal plants such as Asian ginseng, American ginseng, and Notoginseng. Some ginsenosides, especially the 20(R) isomers, are found in trace amounts in natural sources and are difficult to chemically synthesize. The present study provides an approach to produce such trace ginsenosides applying biotransformation through Escherichia coli modified with relevant genes. Methods: Seven uridine diphosphate glycosyltransferase (UGT) genes originating from Panax notoginseng, Medicago sativa, and Bacillus subtilis were synthesized or cloned and constructed into pETM6, an ePathBrick vector, which were then introduced into E. coli BL21star (DE3) separately. 20(R)-Protopanaxadiol (PPD), 20(R)-protopanaxatriol (PPT), and 20(R)-type ginsenosides were used as substrates for biotransformation with recombinant E. coli modified with those UGT genes. Results: E. coli engineered with $GT95^{syn}$ selectively transfers a glucose moiety to the C20 hydroxyl of 20(R)-PPD and 20(R)-PPT to produce 20(R)-CK and 20(R)-F1, respectively. GTK1- and GTC1-modified E. coli glycosylated the C3-OH of 20(R)-PPD to form 20(R)-Rh2. Moreover, E. coli containing $p2GT95^{syn}K1$, a recreated two-step glycosylation pathway via the ePathBrich, implemented the successive glycosylation at C20-OH and C3-OH of 20(R)-PPD and yielded 20(R)-F2 in the biotransformation broth. Conclusion: This study demonstrates that rare 20(R)-ginsenosides can be produced through E. coli engineered with UTG genes.

• Proceedings of the KSR Conference
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• 2007.11a
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• pp.1694-1714
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• 2007

This study is to estimate economic benefits of Standardization R&D of Urban Rail System. Benefit was to be realized through standardization of main areas such as train vehicle, railway, power system, and signal system. To derive and calculate the quantitative benefit, the sources of economic impact was divided into three dimensions -operational cost savings, import substitution, and safety effects. Economic effect of the standardization was categorized based on a modified BSC model. Economic benefits from time and labor savings are converted into cost savings. Import substitution and investment multiplier effect have a positive impact in addition to cost savings. The estimation of the standardization R&D of Urban Rail System was conservatively estimated 370 billion Won. Cost effectiveness of standardized safety system was conservatively translated into economic benefit in this analysis. This study provides a practical guide to economic evaluation of the various railway R&D projects.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11a
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• pp.333.2-333
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• 2002

In this paper, standardization activities and trends of ISO TC 108/SC 2(Measurement and evaluation of mechanical vibration and shock as applied to machines, vehicles and structures) are reviewed.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2007.05a
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• pp.141-144
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• 2007

BLUs are major component in LCD industry which occupies 90% or more of FPD market worldwide and BLU market is expected to be expanded continuously according to the trend of miniaturization, slimness, low power consumption and low weight. The larger the BLU market scale, the more important standardization of performance evaluation techniques to clearly prescribe the product specification. Currently the government is promoting the establishment of related laws and coincidence with international standards to cope with agreements such as WTO/TBT, but the nongovernmental standardization activities are not enough to be actualized. Furthermore, BLU related components such as CCFL, EEFL, inverter and reflector are already developed for localization to substitute imports with home products but collective standardization, national standardization, and international standardization are still not done. So, performance specifications and evaluation methods for normal fluorescent lamps or industrial lamps are being adopted and used as national standards and safety certification standards instead. Making these standards enables to prepare a chance to penetrate into global market and to promote world best products. Also, by making this collective standard, it provides chances to take part in international standardization activities, to protect domestic industries and technologies, to obtain the trend of advanced technologies, and to be predominant over other countries. That is to say, CCFL standardization helps raise 21st century national strategic technology policy and go ahead of globalization of core technologies.

• Proceedings of the KIEE Conference
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• summer
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• pp.1432-1434
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• 2004

Propelled urban rail transit EMU's standardization/localization business receiving MOCT's assistance for 2001 years since 1995 in KRRI. But. urban rail transit is operated because signaling. electrical power. rail etc. as well as EMU connects each other. Therefore, receive MOCT's assistance since 2001 and is achieving standardization research about urban rail transit's infrastructure including signaling. Specially, is propelling standardization about CBTC way for expansive standardization hereafter in signaling part. Main contents of this urban rail transit's signaling standardization research are as following. - standard specification creation - development of core equipment for standardization specification verification - standard specification completion by core equipment testing & evaluation Is explaining about establishment of scheme and these contents for this urban rail transit's signaling's standard specification creation in this paper.

• Journal of Applied Reliability
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• v.15 no.2
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• pp.108-123
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• 2015

Test and Evaluation (T&E) have been verifying the level of it's technological skill and the needed operational status of the development weapons. If the overall spectrum of test and evaluation is fulfilled substantially in the production & deployment, the needed level of the weapon system will be enhanced and also the reliability status will become higher considerably. We can know currently these issues through the mass media and all kinds of the news regarding the defense industry and programs. And so this article have studied the method of enhancing reliability of the test and evaluation, the 6 variables were selected through the discussion of the professional group. The the test and evaluation group needs consistently the professional training systems. After DT&E, we have to the event to verify the technical level of the development systems. We have to take the high level of the kinds of the environmental test. Scientific methods like system engineering will be adapted in process of the test and evaluation. The number of suitable test prototype in the test and evaluation is analysed more systematically. And we need to establish the standardization of the test and evaluation. If 6 variables are well analysed and adapted in the working field, the reliability of the test and evaluation will be considerably, the defense industry will take the chance to develope the future-oriented.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.13 no.2
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• pp.43-50
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• 2007

The production, distribution, and consumption of Korean medicinal herbs have increased every year because of an increase of health considerations. But there are no sufficient standardization procedures in packaging and distribution systems related to these herb products. The standardization of packaging material and dimension could be a good addition for establishing proper quality control methods for Korean medicinal herbs. Medicinal herbs deteriorate under physical, chemical and biological hazards such as oxidation, textural change under high moisture content, color change by light, sanitation problems by insect invasion and contamination. Packaging standardization with proper functional packaging materials is critical to ensure the qualities of medicinal herbs. Also, storage and distribution efficiencies can be improved by achieving packaging dimension standardization. This review summarizes recent research trends related to quality evaluation methods and major quality deterioration factors of Korean medicinal herbs. This paper also offers reviews on some of problems and challenges in current packaging and distribution systems of medicinal herb industries and briefly suggests advanced quality control methods through packaging standardization.