• Title/Summary/Keyword: Estimates

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Comparison of Glomerular Filtration Rate Using Gates Method and Serum Creatinine (Gates 방법과 혈청 크레아티닌을 이용한 사구체 여과율의 비교)

  • Yun, Jong-Jun;Lee, Hyo-Yeong;Lee, Hwa-Jin;Lee, Mu-Seok;Song, Hyeon-Seok;Park, Se-Yun;Jeong, Ji-Uk
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.3
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    • pp.61-66
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    • 2009
  • Purpose: Glomerular filtration rate (GFR) is considered as the best overall index for the level of renal function, diagnosis of doubtful kidney disease, progress observation from chronic kidney disease and is measured with the various methods. In this study, We measured standard GFR by Gates method and attempted to compare the result with serum creatinin-based, Cockcroft-Gault(C-G) formula and Modification of Diet in Renal Disease (MDRD) formula. Materials and methods: 217 patients (127 men, 90 women, mean age $51.3{\pm}16.9$) with various renal function were examined. we compared the GFR using $^{99m}Tc$-DTPA (Gates), C-G formula and MDRD formula. Results: Significant correlations were noted between 2 different GFR estimates (from C-G formula: r=0.864, p<0.0001, MDRD formula: r=0.831, p<0.0001) and $^{99m}Tc$-DTPA (Gates) GFR. Average of serum creatinine (Scr) was measured with $3.0{\pm}3.1\;mg/dL$, In patients with normal renal function (Scr<1.5 mg/dL), $^{99m}Tc$-DTPA (Gates) GFR was statistically significant to C-G formula (p<0.0001) and MDRD formula (p<0.0001). In patients with mild to moderate renal insufficiency (1.5$^{99m}Tc$-DTPA (Gates) GFR was not statistically significant to C-G formula (p=0.181) and MDRD formula (p=0.127). In patients with severe renal insufficiency (Scr>4.0mg/dL), $^{99m}Tc$-DTPA (Gates) GFR was statistically significant to C-G formula and MDRD formula (p<0.0001). Conclusions: Glomerular filtration rate using Gates method was closly correlated to C-G formula and MDRD formula. In patients with normal renal function, $^{99m}Tc$-DTPA (Gates) GFR was significantly lower than C-G formula and MDRD formula. In patients with mild to moderate renal insufficiency, $^{99m}Tc$-DTPA (Gates) GFR was simmilar with C-G formula and MDRD formula. In patients with severe renal insufficiency, $^{99m}Tc$-DTPA (Gates) GFR was significantly higher than C-G formula and MDRD formula. None of the three different methods was clearly superior to the others.

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Studies on the Estimation of the Genetic Parameters on All Traits in Korean Native Ogol Fowl II. Estimations of the Heritabilities and Genetic Correlations on Egg Components (한국재래오골계의 제형질에 대한 유전모수추정에 관한 연구 II. 난구성분에 대한 유전력 유전상관추정)

  • 한성욱;상병찬;백승봉
    • Korean Journal of Poultry Science
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    • v.16 no.4
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    • pp.193-199
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    • 1989
  • This study was conducted to estimate heritabilities and genetic correlations on egg compositions in Korean Native Ogol Fowl. The date analysis were a total of 58,320 eggs in 450 pullets producted from 150 dams and 20 sires of Korean Native Ogol Fowl raised at Chungnam National University from June 18. 1987 to April 6. 1989. The results obtained are summarized as follows: 1. On the egg compositions, the albumen weight at first egg, 300 and 500 days were $24.003\pm$2.499, $28.354\pm$2.755 and $31.863\pm$3.341g; the yolk weight were $10.272\pm$1.536, $16.346\pm$1.321 and $19.212\pm$1.661g: the shell weight were $3.906\pm$0.414, $4.336\pm$0.506 and $4.822\pm$0.515g, respectively. 2. The heritability estimates of egg compositions based on the valiance of sires, dams and combined components were 0.620-0.723, 0.206-0.300 and 0.413-0.511 for albumin weight;0.439-0.737, 0.484-0.544 and 0.492-0.615 for yolk weight:0.172-0.187, 0.412-0.642 and 0.390-0.503 for shell weight, respectively. 1. The genetic and phenotypic correlation coefficients of egg compositions were as follows; The coefficients between albumen weight and yolk weight were 0.089-0.654 and 0.084-0.255;between albumen weight and shell weight were 0.396-0.925 and 0.225-0.544; between yolk weight and shell weight were 0.227-0.357 and 0.098-0.358 respectively.

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Studies on the Estimation of Productivity Improvement of Layer on the Basis of Random Sample Test (경제능력 검정성적을 기초로 한 산란계의 생산성 향상도 추정 연구)

  • 송상정;정선부;박응우;오세정
    • Korean Journal of Poultry Science
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    • v.16 no.4
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    • pp.239-252
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    • 1989
  • The present study was carried out to investigate the improvement of major production traits with the published data of twenty-two years'random sample tests held in Korea from 1966 to 1988. Eight traits-roaring viability, laying viability, age of sexual maturity, hen day egg production, hen-housed egg production, egg weight, feed requirement, 500 days body weight-were dealt with in this study. The results obtained in this study are summerized as follows; 1. Total mean value for rearing viability was 99.4% in 1980s. Mean value for rearing viability of colored hen was 99.5% and white hen was 99.06% in 1980s. Mean value for laying viability was increased by 0.98%, 0.86% and 0.86% per year in pool data, white hen and colored hen, respectively. 2, Age of sexual maturity was decreased from 171.1 day to 160.8 day in pool data during 1960s- 1910s but increased to 162.4 day in 1980s; and decreased from 160.5 day to 1595 nay in white hen but increased from 163.7 day to 166.1 day in colored hen during 1970s-1980s. 3. Mean values for hen-day egg production were increased by 0.96%, 1.09% and 0.63% per year in pool data, colored hen and white hen, respectively. 4. Mean values for hen housed egg production were increased by 45, 5.37 and 4.23 per year in pool data, colored hen and white hen, respectively. 5. Egg weight were improved by 0.22g and 0.25g per year in pool data and colored hen but decreased by 0.03g in white hen. 6. feed requirement were improved by 0.04, 0.05 and 0.1 per year in pool data, white hen and colored hen, respectively. 7. 500 days body weights were increased by 0.38g per year in pool data but decreased by 14.95g and 10.37g in colored hen and white hen, respectively. 8. Estimate of correlation coefficient between age of sexual maturity and other factors such as hen day egg production. hen housed egg production, egg weight and 500 days body weight were -0.4512, -0.2876, -0.4376 and 0.2045 in pool data; -0.358, -0.1530 0.3475 and 0.1208 in white hen; 0.0989, 0.1181, 0.2885 and 0.2248 in colored hen, respectively. Estimates of correlation coefficient between hen day egg production and egg weight were 0.6233, -0.2259 and 0.2973 in Pool data, white hen and colored hen; between hen day egg production and 500 days body weight, 0.2417, 0.0774, -0.4787 : between hen-housed egg production and egg weight, 0.6171, -0.2706, 0.4579: between hen housed egg production and 500 days body weight, 0.3082, -0.0792, -0.3368: between egg weight and 500 days body weight, 0.2742, 0.2205, 0.1354, respectively.

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Empirical Estimation and Diurnal Patterns of Surface PM2.5 Concentration in Seoul Using GOCI AOD (GOCI AOD를 이용한 서울 지역 지상 PM2.5 농도의 경험적 추정 및 일 변동성 분석)

  • Kim, Sang-Min;Yoon, Jongmin;Moon, Kyung-Jung;Kim, Deok-Rae;Koo, Ja-Ho;Choi, Myungje;Kim, Kwang Nyun;Lee, Yun Gon
    • Korean Journal of Remote Sensing
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    • v.34 no.3
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    • pp.451-463
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    • 2018
  • The empirical/statistical models to estimate the ground Particulate Matter ($PM_{2.5}$) concentration from Geostationary Ocean Color Imager (GOCI) Aerosol Optical Depth (AOD) product were developed and analyzed for the period of 2015 in Seoul, South Korea. In the model construction of AOD-$PM_{2.5}$, two vertical correction methods using the planetary boundary layer height and the vertical ratio of aerosol, and humidity correction method using the hygroscopic growth factor were applied to respective models. The vertical correction for AOD and humidity correction for $PM_{2.5}$ concentration played an important role in improving accuracy of overall estimation. The multiple linear regression (MLR) models with additional meteorological factors (wind speed, visibility, and air temperature) affecting AOD and $PM_{2.5}$ relationships were constructed for the whole year and each season. As a result, determination coefficients of MLR models were significantly increased, compared to those of empirical models. In this study, we analyzed the seasonal, monthly and diurnal characteristics of AOD-$PM_{2.5}$model. when the MLR model is seasonally constructed, underestimation tendency in high $PM_{2.5}$ cases for the whole year were improved. The monthly and diurnal patterns of observed $PM_{2.5}$ and estimated $PM_{2.5}$ were similar. The results of this study, which estimates surface $PM_{2.5}$ concentration using geostationary satellite AOD, are expected to be applicable to the future GK-2A and GK-2B.

Quantification of Myocardial Blood flow using Dynamic N-13 Ammonia PET and factor Analysis (N-13 암모니아 PET 동적영상과 인자분석을 이용한 심근 혈류량 정량화)

  • Choi, Yong;Kim, Joon-Young;Im, Ki-Chun;Kim, Jong-Ho;Woo, Sang-Keun;Lee, Kyung-Han;Kim, Sang-Eun;Choe, Yearn-Seong;Kim, Byung-Tae
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.3
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    • pp.316-326
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    • 1999
  • Purpose: We evaluated the feasibility of extracting pure left ventricular blood pool and myocardial time-activity curves (TACs) and of generating factor images from human dynamic N-13 ammonia PET using factor analysis. The myocardial blood flow (MBF) estimates obtained with factor analysis were compared with those obtained with the user drawn region-of-interest (ROI) method. Materials and Methods: Stress and rest N-13 ammonia cardiac PET imaging was acquired for 23 min in 5 patients with coronary artery disease using GE Advance tomograph. Factor analysis generated physiological TACs and factor images using the normalized TACs from each dixel. Four steps were involved in this algorithm: (a) data preprocessing; (b) principal component analysis; (c) oblique rotation with positivity constraints; (d) factor image computation. Area under curves and MBF estimated using the two compartment N-13 ammonia model were used to validate the accuracy of the factor analysis generated physiological TACs. The MBF estimated by factor analysis was compared to the values estimated by using the ROI method. Results: MBF values obtained by factor analysis were linearly correlated with MBF obtained by the ROI method (slope = 0.84, r = 0.91), Left ventricular blood pool TACs obtained by the two methods agreed well (Area under curve ratio: 1.02 ($0{\sim}1min$), 0.98 ($0{\sim}2min$), 0.86 ($1{\sim}2min$)). Conclusion: The results of this study demonstrates that MBF can be measured accurately and noninvasively with dynamic N-13 ammonia PET imaging and factor analysis. This method is simple and accurate, and can measure MBF without blood sampling, ROI definition or spillover correction.

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Evaluation of Genetic Ability for Meat Quality in Hanwoo Cow (육질개량을 위한 한우번식우의 유전능력평가)

  • Won, Jung-Il;Kim, Jong-Bok;Lee, Jeong-Koo
    • Journal of Animal Science and Technology
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    • v.52 no.4
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    • pp.259-264
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    • 2010
  • This study was carried out to estimate genetic parameters and breeding values of Hanwoo cows for carcass traits. Carcass records were collected from Korean steers raised at the private farms located in rural area of Gangwon-do and slaughtered from December 2004 to June 2008 at the three slaughter houses near fattening farm. The results obtained in this study were summarized as follows; The means and standard deviations of the carcass traits were $5.57{\pm}2.01$ for marbling score (MS), $10.87{\pm}4.06mm$ for backfat thickness (BFT), $87.87{\pm}9.07cm^2$ for eye muscle area (EMA), $426.75{\pm}49.27kg$ for carcass weight (CW), and $65.80{\pm}3.80$ for yield index (YI). Heritability estimates using single trait analyses were 0.36 for MS, 0.35 for BFT, 0.24 for EMA, 0.29 for CW, and 0.40 for YI, respectively. Genetic correlation coefficients of MS with BFT, EMA, CW, and YI were -0.21, 0.30, -0.21 and 0.30, and those of BFT with EMA, CW and YI were -0.12, 0.57 and -0.97, and those of EMA with CW and YI were 0.32 and 0.27, respectively. And genetic correlation of CW with YI was -0.62. Single trait selection for MS might lead to reducing BFT, but might be an obstacle to increase CW due to negative genetic correlations of MS with BFT and CW.

Estimation of Environmental Effect and Genetic Parameter on Reproduction Traits for On-farm Test Records (농장검정돈의 번식형질에 미치는 환경효과 및 유전모수의 추정)

  • Jung, D.J.;Kim, B.W.;Roh, S.H.;Kim, H.S.;Moon, W.K.;Kim, H.Y.;Jang, H.G.;Choi, L.S.;Jeon, J.T.;Lee, J.G.
    • Journal of Animal Science and Technology
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    • v.50 no.1
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    • pp.33-44
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    • 2008
  • The purpose of this study was to estimate the genetic parameters and trend of Landrace and Yorkshire pigs, which were raised on private farms from 1999 to 2005 and tested for their reproductive performance by the Korea Animal Improvement Association. Prior to analysis, records without pedigree or having value with larger than±3×standard deviation for the Total number of born were excluded. The effects of breed and environmental factors were estimated with least square method(Harvey, 1979), and estimation of breeding values and genetic parameters were performed on the data of 1’st litter only with GIBBSF90(Misztal, 2001) which was programmed according to Gibbs Sampling method based on Bayesian Inference by Gianola and Fernando(1986), Jensen(1994) and others. Gibbs sampling was performed 50,000 times for each parameter, and the first 5000 samples were regarded as those in burn-in period and thus, excluded for post hoc analysis. Total number of born and total number of accident were statistically significant(p<0.01) for the breed, farrowing year, farrowing season and parity effects, and the number born alive at birth was statistically significantp<(0.01) for the breed, farrowing year, farrowing season and parity effects. No particular trend was observed in the genetic and phenotypic improvement of the total number of born and number born alive at birth before 2001, when the piglet registration system started, but the tendencies of increasing for the total number of born and number born alive and decreasing for the total number of accident were observed since 2001. Somewhat higher heritability estimates of our study seems to be attributed to the situations that first parity records with poor farrowing performances were used in the analyses and it was impossible to obtain accurate reproductive performance due to the absence of criteria for record keeping at the level of individual farms.

Estimation of Genetic Parameters for Milk Production Traits in Holstein Dairy Cattle (홀스타인의 유생산형질에 대한 유전모수 추정)

  • Cho, Chungil;Cho, Kwanghyeon;Choy, Yunho;Choi, Jaekwan;Choi, Taejeong;Park, Byoungho;Lee, Seungsu
    • Journal of Animal Science and Technology
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    • v.55 no.1
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    • pp.7-11
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    • 2013
  • The purpose of this study was to estimate (co) variance components of three milk production traits for genetic evaluation using a multiple lactation model. Each of the first five lactations was treated as different traits. For the parameter estimation study, a data set was set up including lactations from cows calved from 2001 to 2009. The total number of raw lactation records in first to fifth parities reached 1,416,589. At least 10 cows were required for each contemporary group, herd-year-season effect. Sires with fewer than 10 daughters were discarded. Lactations with 305d milk yield exceeding 15,000 kg were removed. In total, 1,456 sires of cows were remained after all the selection steps. A complete pedigree consisting of 292,382 records was used for the study. A sire model containing herd-year-season, caving age, and sire additive genetic effects was applied to the selected lactation data and pedigree for estimating (co) variance components via VCE. Heritabilities and genetic or residual correlations were then derived from the (co) variance estimates using R package. Genetic correlations between lactations ranged from 0.76 to 0.98 for milk yield, 0.79~1.00 for fat yield, 0.75~1.00 for protein yield. On individual lactation basis, relatively low heritability values were obtained 0.14~0.23, 0.13~0.20 and 0.14~0.19 for milk, fat, and protein yields, respectively. For the combined lactation heritability values were 0.29, 0.28, and 0.26 for milk, fat, and protein yields. The estimated parameters will be used in national genetic evaluations for production traits.

Target Advertisement Service using a Viewer's Profile Reasoning (시청자 프로파일 추론 기법을 이용한 표적 광고 서비스)

  • Kim Munjo;Im Jeongyeon;Kang Sanggil;Kim Munchrul;Kang Kyungok
    • Journal of Broadcast Engineering
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    • v.10 no.1 s.26
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    • pp.43-56
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    • 2005
  • In the existing broadcasting environment, it is not easy to serve the bi-directional service between a broadcasting server and a TV audience. In the uni-directional broadcasting environments, almost TV programs are scheduled depending on the viewers' popular watching time, and the advertisement contents in these TV programs are mainly arranged by the popularity and the ages of the audience. The audiences make an effort to sort and select their favorite programs. However, the advertisement programs which support the TV program the audience want are not served to the appropriate audiences efficiently. This randomly provided advertisement contents can occur to the audiences' indifference and avoidance. In this paper, we propose the target advertisement service for the appropriate distribution of the advertisement contents. The proposed target advertisement service estimates the audience's profile without any issuing the private information and provides the target-advertised contents by using his/her estimated profile. For the experimental results, we used the real audiences' TV usage history such as the ages, fonder and time of the programs from AC Neilson Korea. And we show the accuracy of the proposed target advertisement service algorithm. NDS (Normalized Distance Sum) and the Vector correlation method, and implementation of our target advertisement service system.

Structural Safety Assessment of a Sunken Ship Considering Hull Corrosion and Damaged Members - Focus on the Sunken Ship 'No. 7 HaeSung' - (선체 부식 및 손상 부재를 고려한 침몰선박의 구조 안전성 평가에 관한 연구 - 제7 해성호를 중심으로 -)

  • Lee, Seung Hyun;Kim, Won Don;Suh, Jae-Joon
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.19 no.4
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    • pp.332-340
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    • 2016
  • Sunken ships cause damage to the environment due to the dispersal of fuel oil and harmful cargo goods in the hull. Since the sunken ship is mostly flooded by the seabed, it tends to be in a relatively stable condition. However, the heavy body, together with the load of remaining goods in the cargo hold, the constant contact with the seabed, and ocean currents and tidal waves, can affect dispersal of residual fuel oils out of the sunken ship. Corrosion of the sunken ship starts upon sinking, decreasing the thickness of the hull structure and sub-materials. Therefore, it is necessary to assess the structural stability against the potential breakdown of the sunken ship. Whilst evaluating the danger of the sunken ship, this result should be reflected in 'the possible discharge'. This study was undertaken to suggest a procedure for a step by step evaluation to assess the structural stability a sunken ship. The structural stability assessment to estimate the collapsibility of the hull was structure targeted at the sunken ship 'No. 7 HaeSung', which was classified as the prime example for the intensive management of sunken ships. This study was undertaken to suggest a procedure for a step by step evaluation to assess the structural stability a sunken ship and to propose a method to conduct a structural safety assessment that estimates the collapsibility of the hull by targeting the sunken ship 'No. 7 HaeSung',which was classified as the prime example for the intensive management of sunken ships. The collapsibility of the hull structure was estimated Based on the damage size of the hull structure, and the corrosion rate of the hull structure and sub-materials due to the seawater after sinking. It was confirmed that there was a low possibility of the total destruction of the hull structure at the current time. However, there is a high possibility in the potential failure of the hull structure due to increased rate of corrosion thereafter. Therefore, we believe continuous study on influence of corrosion and marine environment change to sunken ship's structural safety is necessary.