• Fire Science and Engineering
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• v.23 no.4
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• pp.145-153
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• 2009

We are generally applicate smoke control only vestibule about special escape staircase, it is one of some smoke control model of NFSC 501A. But there are some point at issue in this system. The smoke control system on supervision field of writer is smoke control only vestibule same as the other resemble field. Writer studied in the concrete to find a solution at this issue, and derived a conclusion the most reasonable system on the field is "same time smoke control for staircase and vestibule" by the engineering analysis considering stack effect.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.1905-1907
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• 2014

Increasingly it is being realized that despite considerable advancements in therapeutic interventions related to treatment of cancer, satisfactory results are still difficult to achieve. Rapidly accumulating evidence has started to shed light on the fact that cancer cells escape from death via constitutive activation of pro-survival signaling cascades. Cell biology and genetics have extensively enhanced our current understanding of the molecular mechanisms that underlie loss of apoptosis in cancer cells. This review is focused on ionizing radiation mediated restoration of TRAIL mediated apoptosis as evidenced by cell culture and animal model studies. Moreover, we also bring to the limelight radiation induced expression of miRNAs and how miRNAs further control response of cancer cells to radiation.

• Journal of the Korea Furniture Society
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• v.14 no.1
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• pp.47-58
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• 2003

Italian furniture companies play a leading role in the world furniture market and are acknowledged as good design trend leader. Their craftsmanship which has been handed down from the past is thoroughly applied to the process of design and production. Two well-known furniture companies in Italy, 'B&B Italia' and 'Kartell', are chosen as a case study model to grasp the key of their success. In general and objective material collecting and researching, this study aims at understanding the method of the advanced corporations' design development, marketing strategy and brand identity This study is expected to use as a research material for Korean furniture industry to escape from the serious depression after IMF shock.

• Fire Science and Engineering
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• v.3 no.2
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• pp.11-19
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• 1989

In this study, the independent variables are the floor plan configulation. The dependent variables are the occupant's egress behavior, especially spatial movement pattern, and life - safety performance of building. Fire events were simulated on single story of office building. Simulation run for allowable secaping thime(180 seconds) arbitrarily selected, and involved 48 occupants. The major findings Pre as follows. 1) Computer simulation model suggested in this study can be used as the Preoccupancy evaluation method of the life-safety performance for architectural design based on prediction of occupants' egress behavior in the levels of validity and sensitivity, 2) Sucess or failure in occupants' escape is determined by decreasing walking speed caused by jamming at exits or over crowded corridor, and increasing route length caused by running about in confusion at each subdivision and corridor. 3) In floor plan configuration which safe areas located at the extreme ends of the corridor, cellular floor planning have to be avoided preventing jamming and running about in confusion at overcrowded corridor.

• Journal of Industrial Technology
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• v.23 no.A
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• pp.9-13
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• 2003

Numerical experiments are done by a commercial code, PHOENICS to evaluate the backlayer phenomenon of smoke in case of the road tunnel fire. The independent and dependent variables are ventilation air velocity and the length of backlayer of smoke respectively. Hybrid scheme and ${\kappa}-{\varepsilon}$ turbulence model are adopted in the simulation process and mass residual is used as a convergence criterion. The experimental results say that the length of backlayer is reduced with the increase of ventilating air velocity and that there is a critical air velocity which prevents from the onset of backlayering phenomena. One finds that there is a fresh air region near the bottom of tunnel which could make the passenger escape safely from the polluted region by smoke. These phenomena come from the vertical stratification of the smoke air mixture in the tunnel.

• Journal of The Korean Astronomical Society
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• v.4 no.1
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• pp.1-8
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• 1971

The average velocity, 330km/sec. of the high velocity stars with respect to the galactic center is obtained from the data used by Fricke on the assumption that the rotational velocity of the Local Standard of Rest is 250km/sec. Comparing this value with the escape velocity, 380km/sec, at the solar neighborhood which is calculated from Mestel's model of the Galaxy, it is shown that most of the high velocity stars are bound to the Galaxy and that their average apogalacticon is about 40 kpc from the galactic center. And the fact that stars with radial velocities larger than 63km/sec are missing in the direction of galactic rotation of L.S.R. is interpreted as the result partly of the random distribution of the directions of motion of the high velocity stars and partly of the observational errors.

• IMMUNE NETWORK
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• v.11 no.6
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• pp.336-341
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• 2011

T cell receptor (TCR) signaling plays a critical role in T cell development, survival and differentiation. In the thymus, quantitative and/or qualitative differences in TCR signaling determine the fate of developing thymocytes and lead to positive and negative selection. Recently, it has been suggested that self-reactive T cells, escape from negative selection, should be suppressed in the periphery by regulatory T cells (Tregs) expressing Foxp3 transcription factor. Foxp3 is a master factor that is critical for not only development and survival but also suppressive activity of Treg. However, signals that determine Treg fate are not completely understood. The availability of mutant mice which harbor mutations in TCR signaling mediators will certainly allow to delineate signaling events that control intrathymic (natural) Treg (nTreg) development. Thus, we summarize the recent progress on the role of TCR signaling cascade components in nTreg development from the studies with murine model.

• Cross-Cultural Studies
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• v.32
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• pp.63-79
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• 2013

Tar Baby, Toni Morrison's fourth novel re examines the problem that black characters face in negotiatiating a place for themselves within a dominant culture, with respect to their own history and culture. The novel critiques the dominant socio economic and commodifying cultural space from which the black woman seems to have no escape. Jadine is a colonized subject, for as a fashion model she has surrendered to an aesthetics of commodification, and as a student of art history, she has internalized the capitalist ethic of the white culture industry. Though she has ensured her freedom, Morrison's critique of her separation from her family and culture is unmistakable. Interwoven with her narrative is Son's predicament, the stereotype of a black racist and her 'lover'. The novel ends with him at the crossroads of culture, yet signaling his passage to freedom through resistance. The paper arguments how Toni Morrison has envisioned the welfare of African American community by reconstructing the role of new black generation, as represented by Jadine and Son, whose new journey towards their self fulfillment just not only bring their personal freedom but also regenerates African American community by resisting dominant commodifying cultural.

• Korea journal of population studies
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• v.11 no.1
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• pp.32-49
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• 1988

The social conditions in Koreas until 1950s were similar to the model phenomena of low level eqilibrium trap which was named by Prof. Nelson, with the continuation of high population growth rate and low economic growth rate. To escape from the trap, Korean government adopted two different policies, one is economic development plans and the other is family planning programs. Theses policies were successful in both increasing the national products and decreasing the population growth rate. In 1985 per capita GNP increased to over two thousand dollars, fertility rate reduced to replacement level(2.1) and unemployment rate was stabilized at 4 percent level. From various prospects, we were successfully escaped from the Malthusian trap and many economists, who studied developed countries, belive that population growth has positive effects on technological progress, economies of scale, specialization, individual attitude on work, and economic growth. Therefore we need to reexamine the anti-natalistic population policy of Korea in this situation.

• BMB Reports
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• v.54 no.7
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• pp.344-355
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• 2021

Mucins are high molecular-weight epithelial glycoproteins and are implicated in many physiological processes, including epithelial cell protection, signaling transduction, and tissue homeostasis. Abnormality of mucus expression and structure contributes to biological properties related to human cancer progression. Tumor growth sites induce inhospitable conditions. Many kinds of research suggest that mucins provide a microenvironment to avoid hypoxia, acidic, and other biological conditions that promote cancer progression. Given that the mucus layer captures growth factors or cytokines, we propose that mucin helps to ameliorate inhospitable conditions in tumor-growing sites. Additionally, the composition and structure of mucins enable them to mimic the surface of normal epithelial cells, allowing tumor cells to escape from immune surveillance. Indeed, human cancers such as mucinous carcinoma, show a higher incidence of invasion to adjacent organs and lymph node metastasis than do non-mucinous carcinoma. In this mini-review, we discuss how mucin provides a tumor-friendly environment and contributes to increased cancer malignancy in mucinous carcinoma.