• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.1905-1907
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• 2014

Increasingly it is being realized that despite considerable advancements in therapeutic interventions related to treatment of cancer, satisfactory results are still difficult to achieve. Rapidly accumulating evidence has started to shed light on the fact that cancer cells escape from death via constitutive activation of pro-survival signaling cascades. Cell biology and genetics have extensively enhanced our current understanding of the molecular mechanisms that underlie loss of apoptosis in cancer cells. This review is focused on ionizing radiation mediated restoration of TRAIL mediated apoptosis as evidenced by cell culture and animal model studies. Moreover, we also bring to the limelight radiation induced expression of miRNAs and how miRNAs further control response of cancer cells to radiation.

• BMB Reports
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• v.50 no.10
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• pp.496-503
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• 2017

The human body loses several billions of cells daily. When cells die in vivo, the corpse of each dead cell is immediately cleared. Specifically, dead cells are efficiently recognized and cleared by multiple types of neighboring phagocytes. Early research on cell death focused more on molecular mechanisms of cell death regulation while the cellular corpses were merely considered cellular debris. However, it has come to light that various biological stimuli following cell death are important for immune regulation. Clearance of normal dead cells occurs silently in immune tolerance. Exogenous or mutated antigens of malignant or infected cells can initiate adaptive immunity, thereby inducing immunogenicity by adjuvant signals. Several pathogens and cancer cells have strategies to limit the adjuvant signals and escape immune surveillance. In this review, we present an overview of the mechanisms of dead cell clearance and its immune regulations.

• Proceedings of the Korea Society for Energy Engineering kosee Conference
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• 1995.05a
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• pp.101-112
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• 1995

In order to improve the recovery efficiency of heavy water vapour from the atmosphere inside a reactor building, and to recover and upgrade the heavy water which escape, special treatments, such as reducing the ingress of light water vapour, are studied in the design of the CANDU reactor systems. This is considered in controlled method of the humidity over drawing fresh air through a desiccant dehumidifier which dries the air by absorption. Comparing with the moisture loads between summer and winter operations, the moisture removal rates are calculated. Those are proportional to the difference between the controlled space and the surrounding environment Installation of a new dehumidifier will be able to reduce the moisture loads from the cooling systems, improving overall system efficiency and saving operating costs.

• Journal of Korean Classical Literature and Education
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• no.15
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• pp.303-327
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• 2008

The purpose of this paper is the analysis of to point its structure and meaning deduced from the rite of passage. In the light of the rite of passage, could be retrieved its value as one of significant works among the works of Gangho-sijo. is composed of nineteen pieces of monotype sijo. The first piece is a kind of prologue. The other pieces are divided into three parts which correspond with the three stages of the rite of passage-separation, transition, incorporation. As a result of this analysis, we can find out the writer's cognitive change according to the schema of the rite of passage. It becomes clear that the space of Gangho means the sacred space for mental culture rather than a separate space for escape. And considering the withdrawal for Gangho as the transition process of the rite of passage, gives a description of the disentanglement of conflict and a incorporation into the superior position of spirit.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.35D no.6
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• pp.79-91
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• 1998

Design principles for high-brightness ligh-temitting diodes have been derived by using escape cone concepts. Based on the design principles, some important high-brightness LED structures developed thus far have been reviewed and, in addition, their external coupling efficiencies have also been estimated. In AlGaAs or InGaAIP LEDs, in which photon absorption in the ohmic electrodes is known to be serious, photon shielding by the electrodes is minimized by using window layer (WL) as well as transparent substrate (TS) leading to significantly improved light-emitting efficiency. However, in InGaN LEDs emitting blue to green lights, the photon absorption in ohmic contact to wide bandgap GaN may be negligible and therefore, photon shielding by the electrodes would not lead to as significant problems as in conventional In AIGaAs or InGaAIP LEDs.

• The Journal of the Convergence on Culture Technology
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• v.5 no.3
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• pp.107-112
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• 2019

Most of the sign systems involved in evacuation are not useful in seismic situations where people have to evacuate with their heads bowed, given that they are at the top of the wall. Based on the analysis and understanding of seismic evacuation situations, this study proposes a sign system as a measure for rapid seismic evacuation. First, understand the seismic situation based on the video analysis of the earthquake evacuation situation. Second, the need for a sign system to help secure evacuation in earthquake situations was derived. Third, the on-site survey examined the suitability of the Sine system installed in Korea as an escape facility for the earthquake evacuation situation. Based on the video analysis and on-site survey, it was concluded that the installation of escape guidance lamps alone could not induce rapid evacuation in the earthquake situation. In this study, a sign system is proposed to help the use of doors by installing a sign system near an emergency exit light.

• Journal of the Korea Institute of Building Construction
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• v.18 no.4
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• pp.363-373
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• 2018

Evacuation facilities are installed so that people can evacuate high-rise apartment houses when it is impossible to escape fire through the front door. The households of apartment houses may escape the building in two ways, which will reduce loss of lives. This study examined the characteristics of two-way evacuation facilities, including a light-weight partition wall, shelter space at the balcony and horizontally-installed indoor emergency exit. Then, it proposed a horizontally-installed outdoor emergency exit that improved the problems of the examined facility types, and analyzed its economic-feasibility. When a horizontally-installed emergency exit instead of a traditional type to escape from fire is used, people may be more autonomous in deciding whether active evacuation is possible or not. Thus, the time required to evacuate the building with 4 different evacuation methods using the stairs and horizontally-installed emergency exit was simulated in consideration of the impact of evacuation methods that people choose on the time required for evacuation using pathfinder. Then, the simulation results were compared and analyzed. Any appropriate evacuation method to reduce the time required for evacuation was predicted, analyzed and decided. As a result of this study, it was analyzed that the high - rise apartment top - down type evacuation zone can shorten the total evacuation time compared to the staircase type.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2002.07a
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• pp.25-37
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• 2002

The most important industrial application of gamma radiation in characterizing green compacts is the determination of the density. Examples are given where this method is applied in manufacturing technical components in powder metallurgy. The requirements imposed by modern quality management systems and operation by the workforce in industrial production are described. The accuracy of measurement achieved with this method is demonstrated and a comparison is given with other test methods to measure the density. The advantages and limitations of gamma ray densitometry are outlined. The gamma ray densitometer measures the attenuation of gamma radiation penetrating the test parts (Fig. 1). As the capability of compacts to absorb this type of radiation depends on their density, the attenuation of gamma radiation can serve as a measure of the density. The volume of the part being tested is defined by the size of the aperture screeniing out the radiation. It is a channel with the cross section of the aperture whose length is the height of the test part. The intensity of the radiation identified by the detector is the quantity used to determine the material density. Gamma ray densitometry can equally be performed on green compacts as well as on sintered components. Neither special preparation of test parts nor skilled personnel is required to perform the measurement; neither liquids nor other harmful substances are involved. When parts are exhibiting local density variations, which is normally the case in powder compaction, sectional densities can be determined in different parts of the sample without cutting it into pieces. The test is non-destructive, i.e. the parts can still be used after the measurement and do not have to be scrapped. The measurement is controlled by a special PC based software. All results are available for further processing by in-house quality documentation and supervision of measurements. Tool setting for multi-level components can be much improved by using this test method. When a densitometer is installed on the press shop floor, it can be operated by the tool setter himself. Then he can return to the press and immediately implement the corrections. Transfer of sample parts to the lab for density testing can be eliminated and results for the correction of tool settings are more readily available. This helps to reduce the time required for tool setting and clearly improves the productivity of powder presses. The range of materials where this method can be successfully applied covers almost the entire periodic system of the elements. It reaches from the light elements such as graphite via light metals (AI, Mg, Li, Ti) and their alloys, ceramics ($AI_20_3$, SiC, Si_3N_4, $Zr0_2$, ...), magnetic materials (hard and soft ferrites, AlNiCo, Nd-Fe-B, ...), metals including iron and alloy steels, Cu, Ni and Co based alloys to refractory and heavy metals (W, Mo, ...) as well as hardmetals. The gamma radiation required for the measurement is generated by radioactive sources which are produced by nuclear technology. These nuclear materials are safely encapsulated in stainless steel capsules so that no radioactive material can escape from the protective shielding container. The gamma ray densitometer is subject to the strict regulations for the use of radioactive materials. The radiation shield is so effective that there is no elevation of the natural radiation level outside the instrument. Personal dosimetry by the operating personnel is not required. Even in case of malfunction, loss of power and incorrect operation, the escape of gamma radiation from the instrument is positively prevented.

• International journal of advanced smart convergence
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• v.6 no.1
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• pp.82-88
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• 2017

Emergency lights and exit signs are an indispensable part of safety precautions for effective evacuation in case of emergency in public buildings. These emergency sign indicates safe escape routes and emergency doors, using an internationally recognizable sign. However visibility of those signs drops drastically in case of emergency situations like fire smoke, etc. and loss of visibility causes serious problems for safety evacuation. This paper propose a novel emergency light and exit sign built-in with Bluetooth Low Energy (BLE) Beacon to assist the emergency self-guiding evacuation using devices for crisis and emergency management to avoid panic condition inside the buildings. In this approach, the emergency light and exit sign with the BLE beacons deployed in the indoor environments and the smart devices detect their indoor positions, direction to move, and next exit sign position from beacon messages and interact with map server in the Internet / Intranet over the available LTE and/or Wi-Fi network connectivity. The map server generate an optimal emergency exit path according to the nearest emergency exit based on a novel graph generation method for less route computation for each smart device. All emergency exit path data interfaces among three system components, the emergency exit signs, map server, and smart devices, have been defined for modular implementation of our emergency evacuation system. The proposed exit sign experimental system has been deployed and evaluated in real-time building environment thoroughly and gives a good evidence that the modular design of the proposed exit sign system and a novel approach to compute emergency exit path route based on the BLE beacon message, map server, and smart devices is competitive and viable.

• Progress in Medical Physics
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• v.16 no.4
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• pp.202-206
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• 2005

Three-dimensional thermoluminescence (TL) spectra from $MgAl_2O_4$ irradiated with UV light were measured over 300${\~}$600 K and 300${\~}$800 nm. The peak positions of TL glow curves were shifted to lower temperature with increasing the exposure time of UV light. The 476 K TL glow curve is due to the second kinetics and its activation energy and escape frequency factor are calculated to be 0.85 eV and $1.92{\times}10^6 sec^{-1}$, respectively The TL spectra were split into 530 nm and 700 nm emission bands which were associated with $V^{2+}$ and $Cr^{2+}$, respectively. The linearity range of 700 nm omission band is smaller than that of 530 nm emission band, but the saturation time of 700 nm emission band is longer than that of 530 nm omission band.