• Journal of Photoscience
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• 제7권4호
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• pp.143-148
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• 2000

Studies have been conducted to explore single electron transfer(SET) promoted photocyclization of ($\omega$-phthalimidoalkoxy)acetic acids(alkoxy=ethoxy, n-propoxy and n-butyloxy). Photocyclizations occur in methanol or acetone in high yields to produce cyclized products in which phthalimide carbonyl carbon is bonded to the carbon of side chain in place of the carboxylic group. These photocyclizations are thought to proceed through pathways involving intramolecular SET from oxygen in the $\alpha$-carboxymethoxy groups to the singlet excited state phthalimide moieties followed by decarboxylation of the intermediate $\alpha$-carboxymethoxy cation fadicals and cyclizations by radical coupling. The photocyclizations occur ca. three times faster in both methanol or acetone with one equivalent of sodium hydroxide added to the reactions and occur slower in acetone than in methanol. The efficient and regiselective cyclization reactions observed for photolyses in methanol represent synthetically useful processes for construction of heterocyclic compounds.

• 한국미생물·생명공학회지
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• 제44권3호
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• pp.278-284
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• 2016

기능성으로 각광 받는 블루베리, 아로니아, 귀리, 단호박, 생강의 국내외 중간소재를 구입하여 기능성 성분을 비교, 분석하였다. 시판 중간소재 80% 메탄올 추출물의 Total phenolics contents (TPC), total anthocyanins contents (TAC), total flavonoids contents (TFC)를 측정하였고, ABTS radical 소거능, DPPH radical 소거능을 통해 항산화능을 측정 후, 통계적 유의성을 분석하였다. TPC (mg gallic acid equivalent/100 g dried sample)와 TFC (mg catechin equivalent/ 100 g dried sample)의 경우, 모두 국내산 블루베리(TPC, 2,917 ± 200; TFC, 1,327 ± 31)와 단호박(TPC, 476 ± 20, TFC, 23 ± 2)이 국외산 보다 높았고, 국외산은 아로니아, 귀리, 생강의 중간소재가 더 높았다. TAC (mg cyaniding-3-glucoside/100 g dried sample)는 국내산 블루베리(949 ± 57), 국외산 아로니아(2,032 ± 153)가 각각 높았다. 항산화능(mg vitamin C equivalent/100 g dried sample)은 ABTS radical 소거능의 경우, 국내산 블루베리(7,050 ± 321), 단호박(311 ± 8), 생강(3,322 ± 109)이 국외산보다 높았고, DPPH radical 소거능의 경우, 국외산 아로니아(12,667 ± 437), 생강(2,067 ± 99) 중간소재가 국내산보다 높게 나왔다. 이와 같이 국외산 중간소재와의 비교를 통해 국내산 농산물을 이용한 중간소재의 기능성 성분에 관한 기초자료를 제공하고, 새로운 기능성 중간소재 개발에 활용할 수 있을 것이다.

• 한국식품영양학회지
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• 제34권1호
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• pp.69-78
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• 2021

The aim of this study was to evaluate the basic data of Cirsium setidens Nakai fine powder (FPC), which will then be used in the development of functional fooditems. We measures and evaluated the level of pectolinarin content, phenol content, flavonoids content, antioxidants and anti-obesity properties of FPC. Our results from the study showed that the pectolinarin, phenol, and flavonoids contents of FPC measured at 10.95±0.1 5mg/g, 12.92±0.18 mg gallic acid equivalent (GAE)/g and 26.47±0.77 mg rutin equivalent (RE)/g, respectively. The exhibited antioxidant activity of FPC increased significantly depending on the dosage, and additionally. FPC did not show any cytotoxicity up to the dosage level of 500 μg/mL. During adipocyte differentiation, FPC significantly inhibited ROS production and lipid accumulation, compared with the control substance. These results suggest that FPC could be considered a promising resource of natural antioxidants and could serve a variety of health-improving roles in the production of functional food ingredients.

• Food Science and Biotechnology
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• 제18권4호
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• pp.1051-1054
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• 2009

This study was conducted to investigate the antioxidant activity of the extracts of lotus (Nelumbo nucifera Gaertner). The total phenolic contents in leaf, stem, and root were 165, 74, and 30 tannic acid equivalent mg/g of dried extract or fraction respectively. The butanol and ethylacetate fractions of lotus parts showed higher 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity than other fractions. 2,2'-Azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) cation radical scavenging activity also showed the similar result as the DPPH radical scavenging activity. The antioxidative capacity of the ethylacetate fraction was the highest among fractions and its fraction showed higher contents of total polyphenol.

• 식품과학과 산업
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• 제51권4호
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• pp.325-333
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• 2018

If private discipline replace the strict administrative regulation, fundamental rights of protective essence can be relativized while if may be beneficial for the individual freedom. Assigning the state power to the private organization is equivalent to giving up the practice of individual liberty to the organized authority. It is important to make use of public law mechanism, particularly under the imperfect juristic system. Regarding the prohibition of prior censorship, it is necessary to consider whether it is desirable to prioritize the freedom of speech over the rest of the legal benefit. Apart from this necessity, new advertisement screening mechanism was irreversibly - and controversially - introduced for the health functional food since the unconstitutional verdict of the prior screening of advertisements. With this, the state must secure the broad order through legal regulations and norms in order to freedom of speech and other legal benefit can be harmoniously and practically guaranteed.

• 대한간호학회지
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• 제37권2호
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• pp.163-170
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• 2007

Purpose. Despite the high prevalence of back pain and its subsequent effects in post-partum women, intervention programs are scarce. The purpose of this study was to test the effects of a back-pain-reducing program on post-partum women who experienced low-back pain during pregnancy. Methods. A non-equivalent control-group pretest-posttest design was used. Pregnant women who attended a hospital for prenatal check-ups and experienced back pain participated in an intervention program (n=27), and the results were compared with women in a control group from another hospital (n=25). Results. At 8 weeks post-partum, the pain intensity, functional limitations were lower in the intervention group than in the control group. However, differences in mean change of the pain intensity and functional limitations between 36 and 39 weeks of gestation and at 8 weeks post-partum were not statistically significant between the groups. Moreover, the flexibility, post-partum functional status, and post-partum depression did not differ significantly between the groups. Conclusions. A back-pain-relief program in this study was not effective to reduce the back-pain intensity in post-partum women and to decrease the associated functional limitations. The implications for nursing practice and directions for future research are discussed.

• 한국컴퓨터정보학회논문지
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• 제22권6호
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• pp.109-114
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• 2017

In this paper, I propose the effects of food therapy on subjects' health and happiness. The result has come out that food therapy enhances subjects' multi-dimensional health(medical, functional, self-evaluative) and their happiness. The participants were 230 adults over 30 years old living in Seoul and Gyeonggi district. To examine the effect of food therapy, the study sampled 220 questionnaire out of 230. By the non-equivalent control group design, the health levels were measured in three concepts: medical dimension, functional dimension and self-evaluative dimension. The results are as follows: First, participants who had taken food therapy for 3 months have been enhanced in their subjective and functional health level. Their subjective health enhanced from $2.80{\pm}.44$ to $4.07{\pm}.27$ (p=.000). And their functional health enhanced from $.92{\pm}.07$ to $.94{\pm}.07$(p=.035). Second, participants' happiness has enhanced significantly. Cognitive happiness enhanced from $3.39{\pm}.50$ to $3.84{\pm}.44$(p=.000). And emotional happiness enhanced from $2.76{\pm}.44$ to $3.07{\pm}.34$(p=.000). With this results, in case that people apply food therapy based on Yaksun, they are able to expect their enhancement of health level and happiness. Therefore study shows that Food therapy helps people to pursue their health and happiness improvement and suggest valuable information of a way to enhance quality of life.

• 한국식품영양과학회지
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• 제41권3호
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• pp.302-309
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• 2012

조와 기장의 항산화성분 및 항산화활성에 미치는 재배시기의 영향을 규명하고자 재배시기를 달리하여 수확된 시료 메탄올 추출물의 항산화성분 및 항산화활성을 분석하였다. 재배시기에 따른 조와 기장 메탄올 추출물의 총 폴리페놀, 플라보노이드, 탄닌 등의 항산화성분의 함량과 DPPH 및 ABTS radical 소거활성은 품종 및 재배시기별로 유의적인 차이를 보이는 것으로 나타났다. 총 폴리페놀 함량은 황금조, 청차조, 삼다메 및 경관1호의 경우 만기재배에서, 경관2호는 보통기재배에서, 강해조는 조기와 만기재배에서 비교적 높은 함량을 보였고 기장의 경우 전체적으로 만기재배에서 높은 함량을 나타냈다. 총 플라보노이드 함량은 황금조와 경관2호는 보통기재배에서, 청차조, 삼다메 및 경관1호는 조기재배에서, 강해조는 만기재배에 높은 함량을 보였고 기장은 만기재배에서 높은 함량을 보였다. 총 탄닌 함량은 황금조는 조기재배에서, 청차조, 삼다메 및 강해조는 만기재배에서, 경관2호는 보통기재배에 높은 함량을 보였고 기장은 만기재배에서 조기나 보통기재배보다 높은 함량을 보였다. 조의 DPPH radical 소거활성은 황금조, 삼다메 및 강해조는 만기재배에서, 청차조와 경관2호는 보통기재배에서, 경관1호는 조기재배에서 높은 활성을 나타냈으며, 기장은 전체적으로 만기재배에서 높은 활성을 나타내었다. ABTS radical 소거활성은 황금조, 경관1호 및 강해조는 만기재배에서, 청차조, 삼다메 및 경관2호는 보통기재배에서 높은 활성을 나타내었고 기장은 만기재배에서 높은 활성을 나타내었다. 이상의 항산화성분 함량 및 항산화활성을 분석한 결과에서 조의 경우 조기재배보다는 보통기 내지 만기재배가 유리할 것으로 보이며, 기장은 만기재배가 유리할 것으로 생각된다.

• 대한한의학회지
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• 제31권1호
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• pp.1-13
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• 2010

Objective: Functional dyspepsia is a prevalent disease. It impedes subjective quality of life. The purpose of this study was to examine the equivalent effect of herb medicine treatment (DA-9701) for functional dyspepsia. Methods: In this randomized, single-blinded, placebo-controlled study, we compared a herb medicine (DA-9701) with standard treatment (mosapride) and placebo for the treatment of functional dyspepsia. 42 volunteers who satisfied the requirements were enrolled in study. Severity of dyspepsia was measured by Nepean Dyspepsia Index (NDI) and Functional Dyspepsia Quality of Life (FD-QOL) before and after treatments. Results: 1. In the DA-9701 group, total key symptoms score was significantly lower and improve rate of key symptoms was higher than in the mosapride and placebo groups, but there were no statistically significant differences between three groups. 2. In the DA-9701 and mosapride groups, "nausea" and "bad breath" were significantly lower compared with the placebo group. 3. In the DA-9701 group, NDI Quality of Life scores were significantly higher, but there were no [other] statistically significant differences between the three groups. 4. In the DA-9701 and mosapride groups, FD-QOL scores were higher compared with the placebo group, but there were no statistically significant differences between the three groups. Conclusion: Herb medicine treatment (DA-9701) is effective to improve the symptoms and quality of life in patients with functional dyspepsia.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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• pp.92-94
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• 2007

This paper considers an optimal control problem for a remote control to an electrical drive system with a DC motor. Since it is a linear control system with time-delay subject to unknown but bounded disturbance, we construct a worst-case feedback control policy. This policy can guarantee that, for all admissible uncertain disturbances, the real system state should be in a prescribed neighborhood of a desired value, and the cost functional takes the best guarantee value. The worst-case feedback control policy is allowed to be corrected at one correction point between the initial to the final time, which is equivalent to solving a 1-level min-max problem. Since the min-max problem at the stage does not yield a simple analytical solution, we consider an approximate control policy, which is equivalent and can be solved explicitly m the numerical experiments.