• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.3993-4003
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• 2013

Scientific evidence for the primary prevention of cancer caused by physical activity of regular moderate-intensity or greater is rapidly accumulating in this field. About 300 epidemiologic studies on the association between physical activity and cancer risk have been conducted worldwide. The objectives of this paper were three-fold: (i) to describe briefly the components of physical activity and its quantification; (ii) to summarize the most important conclusions available from comprehensive reports, and reviews of the epidemiologic individual and intervention studies on a role physical activity in cancer prevention; (iii) to present proposed biological mechanisms accounting for effects of activity on cancer risk. The evidence of causal linked physical activity and cancer risk is found to be strong for colon cancer - convincing; weaker for postmenopausal breast and endometrium cancers - probable; and limited suggestive for premenopausal breast, lung, prostate, ovary, gastric and pancreatic cancers. The average risk reductions were reported to be 20-30%. The protective effects of physical activity on cancer risk are hypothesized to be through multiple interrelated pathways: decrease in adiposity, decrease in sexual and metabolic hormones, changes in biomarkers and insulin resistance, improvement of immune function, and reduction of inflammation. As there are several gaps in the literature for associations between activity and cancer risk, additional studies are needed. Future research should include studies dealing with limitations in precise estimates of physical activity and of a lack of consensus on what defines sedentary behavior of individuals and those linked with the proposed biomarkers to cancer risk and controlled exercise intervention trials.

• Archives of Plastic Surgery
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• 제44권2호
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• pp.144-149
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• 2017

Background The purpose of this study was to identify the epidemiologic characteristics of hand tendon injuries in children and to compare these with those of adults. Methods This retrospective study was conducted on acute traumatic tendon injuries of the hand treated at our institution from 2005 to 2013, based on medical records and X-ray findings. Age, sex, hand injured, mechanism of injury, tendons and zones injured, number of affected digits, and comorbidities and complications were analyzed. Patients were divided into 2 groups: a pediatric group (${\leq}15years$) and an adult group (>15 years). Results Over the 9-year study period, 533 patients were surgically treated for acute traumatic tendon injuries of the hand. In the pediatric group (n=76), being male, the right hand, the extensor tendon, complete rupture, the middle finger, and glass injury predominated in hand tendon injuries. In the adult group (n=457), results were similar, but injury to the index finger and knife injury were the most common. An accompanying fracture was more common in the adult group and complication rates were non-significantly different. Conclusions This comparative analysis revealed no significant epidemiologic intergroup differences. The belief that pediatric tendon injuries tend to be less severe is misplaced, and careful physical examination and exploration should be conducted in pediatric cases of hand injury.

• Tuberculosis and Respiratory Diseases
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• 제41권3호
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• pp.289-298
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• 1994

연구배경 : 유행 질환인 마이코플라스마 폐렴의 일반적인 특성을 파악하는데 병원 자료의 이용에 제한점을 극복하고, 이 질환의 좀더 가까운 자연상을 알아보기 위하여 한 지역사회를 중심으로 관찰하였다. 방법 : 1993년 6월 부터 12월 까지 6개월 동안 전남의 한 해안지방에서 유행한 마이코플라스마 폐렴의 혈청학적으로 확진된 105예와 이에 더하여 같은 기간에 발생한 모든 폐렴으로서 확진되지는 않았으나, 의심되는 경우를 포함한 224명을 대상으로 하여 역학적 및 방사선 소견을 분석하였다. 결과 : 1) 남녀비는 1.5:1 이었다. 2) 연령분포는 5-9 세 사이가 57%로 평균 나이는 6.5세였고, 유행의 시간이 지남에 따라 시기별 평균연령은 낮아지는 추세를 보였다. 3) 인구 집단의 크기보다 집적성이 발생 빈도의 모형에 영향을 준다고 추정되었다. 4) 방사선 소견으로서는 단일 형태로서 간질성 폐렴이 가장 많았으며, 67예(74.5%)에서 한 엽에 국한된 병변을 보였다. 또한 대엽성 폐렴은 학동기에, 간질성 이나 미만성 폐렴은 유아기에 많았다. 결론 : 이상의 특성들은 향후 이 질환의 진단에 도움을 줄 수 있으리라 사료된다.

• Clinical and Experimental Pediatrics
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• 제64권1호
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• pp.3-11
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• 2021

There is a growing body of literature on the adverse health effects of ambient air pollution. Children are more adversely affected by air pollution due to their biological susceptibility and exposure patterns. This review summarized the accumulated epidemiologic evidence with emphasis on studies conducted in Korea and heterogeneity in the literature. Based on systematic reviews and meta-analyses, there is consistent evidence on the association between exposure to ambient air pollution and children's health, especially respiratory health and adverse birth outcomes, and growing evidence on neurodevelopmental outcomes. Despite these existing studies, the mechanism of the adverse health effects of air pollution and the critical window of susceptibility remain unclear. There is also a need to identify causes of heterogeneity between studies in terms of measurement of exposure/outcome, study design, and the differential characteristics of air pollutants and population.

• 농촌의학ㆍ지역보건
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• 제18권2호
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• pp.161-171
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• 1993

Mycoplasma pneumoniae(M. pneumoniae) is a primary pathogene of the respiratory tract in children. Most studies of such pneumonia involve a group of admitted patients in hospital, usually with major medical illness. We retrospectively studied the epidemiologic and clinical feature of 105 patients with serologically proven M. pneumoigic pneumonia treated at Gwang-Yang Hospital during a epidemic period of Jun. 1993 to Dec. 1993. All cases of pneumonia developed in this period were also reviewed and compared with serologically proven group. The results were as follows. 1. There were 63 males and 42 females, and the male /female ratio was 1.5 : 1. 2. More than half(57%) of cases belonged to 5-9 years of age group, and mean age was 6.5 years old. 3. Mean age was steadily decreased as prevalence of mycoplasmal pneumonia had been subsided. 4. The date of index case was June 26th, and that of median case was 3 months after the index case. 5. A major determinant of the outbreak seemed to be the population density rather than the population size. 6. Recurrence and serious complication were not observed in this period. 7. All cases of pneumonia developed in this period might be attributed to M. pnemoniae. These epidemiologic and clinical characteristics would contribute to the prevention and diagnosis of mycoplasmal pneumonia.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.33-34
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• 2001

Cancer chemoprevention Chemoprevention with strategies using food phytochemicals is currently regarded ascompose one of the noticeable most visible and promising scientific fields for cancer control. A large body of data from both epidemiologic and rodent studies has demonstrated that the ingestion of various vegetables and fruits is occasionally beneficial for cancer risk reduction of cancer risks in humans.(omitted)

• Journal of Digestive Cancer Reports
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• 제8권2호
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• pp.97-101
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• 2020

Metformin is a widely used first-line anti-diabetic drug worldwide. Epidemiologic studies using the large population-based cohort database have shown the association between metformin uses and reduced risk of various type cancers including gastric cancer. In the gastric cancer prevention, metformin use was associated with the significant reduction of gastric cancer risk, especially for long-term metformin users. However, there is no well-designed randomized controlled clinical trial investigating the effect of metformin as a chemopreventive drug for gastric cancer. Therefore, further well-designed clinical trials will be needed to implement metformin for chemoprevention of gastric cancer.

• 아동학회지
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• 제19권2호
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• pp.35-47
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• 1998

Negative life events, self-esteem, perceived social support, and maladjustment were studied longitudinally among late elementary children. Subjects were 241 boys and girls for depression and 258 for antisocial behavior. The instruments were the Adolescent Perceived Events Scale, the Rosenberg Self-Esteem Scale, the Social Support Scale for Children, the Revised Korean Version of the Center for Epidemiologic Studies' Depression Scale, and the Antisocial Behavior Scale. The results showed that the way variables were reciprocally related to one another in patterns over a period of one year differed by internal and external adjustment. For depression, depression at Time 1 had effects on self-esteem, social support, and depression at Time 2. For antisocial behavior, negative life events at Time 1 influenced negative life events, self-esteem, social support, and antisocial behavior at Time 2. The findings were discussed in relation to the effects of negative life events, self-esteem, and perceived social support on maladjustment.

• 아동학회지
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• 제18권1호
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• pp.39-52
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• 1997

This study focused on factors influencing Internal and external problem (depression and antisocial) behavior among late-elementary children. Subjects were 481 boys and girls enrolled in the fourth. fifth. and sixth grades of public school. The contribution of grade. sex. stress, self-esteem. and social support from parents, teachers, and friends as well as school performance were studied. The instruments were the Adolescent Perceived Events Scale, the Self-Esteem Scale, the Social Support Scale for Children, the Revised Korean Version of the Center for Epidemiologic Studies' Depression Scale and Antisocial Behavior Scale. Results indicated that sex, stress, self-esteem, and the support of parents, teachers and friends reduced the level of depression. Grade, sex, stress, self-esteem, and teachers' support were related to the level of antisocial behavior. The results were discussed in terms of the effects of stress, personal and social resources, and school achievement on depression and antisocial behavior.

• 대한영양사협회학술지
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• 제19권2호
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• pp.124-139
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• 2013

Unlike studies of Europeans and Americans, many epidemiological studies of the Korean population have indicated that their risk for cardiovascular disease does not decrease with a vegetable-rich diet. The different dietary practices of Koreans, who consume salted vegetables instead of fresh vegetables (common in the Western diet), has been suggested as a reason for this observation. Korea is in a period of rapid epidemiologic transition, which includes dietary and disease patterns; therefore, this study investigated differences in the food consumption pattern and blood lipid profiles of Koreans compared to Europeans and Americans. The identification of dietary patterns related to blood lipid abnormalities was carried out using the 2007~2009 Korean National Health and Nutrition Survey data from 14,056 subjects. Dietary patterns were analyzed according to food group and nutrient intake. Blood lipid abnormalities were classified into three groups: hypercholesterolemia, hypertriglyceridemia, and low HDL cholesterolemia (hypo-HDL-cholesterolemia). The prevalence of hypercholesterolemia, hypertriglyceridemia, and hypo-HDL-cholesterolemia was 12.4%, 16.2%, and 27.7% respectively. In our analysis, the low consumption of all food groups was related to hypercholesterolemia. The high consumption of vegetable-containing foods, alcoholic beverages, and the low consumption of milk products were associated with hypertriglyceridemia and hypo-HDL-cholesterolemia. Thus, unlike Europeans and Americans, the low consumption of all food groups is related to hypercholesterolemia and a low consumption of milk products is related to hypertriglyceridemia and hypo-HDL-cholesterolemia. Dietary pattern might play a role in epidemiologic transition of Korean. Also, this study implies necessity of further research using longitudinal data.