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Evaluation of skin improvement efficacy of herbal medicine extracts on skin keratinocytes stimulated with fine dust PM10 (미세먼지 PM10으로 손상을 유도한 피부각질형성세포에서 한약재 추출물의 피부 개선 효능 평가)

  • Dong-Hee Kim;Yun Hwan Kang;Bo-Ae Kim
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.4
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    • pp.856-867
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    • 2023
  • Due to the increase in fine dust caused by environmental pollution, oxidative damage and aging of the skin are accelerated. In this study, the antioxidant, hyaluronic acid, filaggrin, MMP-1, and ROS level of selected herbal extracts were evaluated to confirm the protective efficacy of keratinocytes treated PM10. As a result, the antioxidant capacity of 1,1-diphenyl-2-picrylhydrazyl(DPPH), 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid(ABTS), and FRAP assay increased in a concentration-dependent manner. Keratinocytes the group treated with 300 ㎍/ml of PM10, hyaluronic acid and filaggrin decreased by more than 50%, and increased in the group treated with extracts of Alpinia officinarum, Ulmus macrocarpa, and Ulmus macrocarpa but decreased when the extract was treated, which is evaluated as inhibiting the degradation of collagen and elastin. In addition, in the case of ROS measurement using zebrafish embryos, it was confirmed that the extract was reduced when the extract was treated 25 ㎍/ml, the intensity of fluorescence similar to the negative control was shown, confirming that the production of ROS was significantly reduced. Through this study, the selected oriental medicinal materials, Alpinia officinarum, Ulmus macrocarpa, and Ulmus macrocarpa, protect the skin from fine dust. It is thought that it can be used as an anti-aging product for skin improvement as a material that can be improved or improved.

Dynamic Shear Behavior Characteristics of PHC Pile-cohesive Soil Ground Contact Interface Considering Various Environmental Factors (다양한 환경인자를 고려한 PHC 말뚝-사질토 지반 접촉면의 동적 전단거동 특성)

  • Kim, Young-Jun;Kwak, Chang-Won;Park, Inn-Joon
    • Journal of the Korean Geotechnical Society
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    • v.40 no.1
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    • pp.5-14
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    • 2024
  • PHC piles demonstrate superior resistance to compression and bending moments, and their factory-based production enhances quality assurance and management processes. Despite these advantages that have resulted in widespread use in civil engineering and construction projects, the design process frequently relies on empirical formulas or N-values to estimate the soil-pile friction, which is crucial for bearing capacity, and this reliance underscores a significant lack of experimental validation. In addition, environmental factors, e.g., the pH levels in groundwater and the effects of seawater, are commonly not considered. Thus, this study investigates the influence of vibrating machine foundations on PHC pile models in consideration of the effects of varying pH conditions. Concrete model piles were subjected to a one-month conditioning period in different pH environments (acidic, neutral, and alkaline) and under the influence of seawater. Subsequent repeated direct shear tests were performed on the pile-soil interface, and the disturbed state concept was employed to derive parameters that effectively quantify the dynamic behavior of this interface. The results revealed a descending order of shear stress in neutral, acidic, and alkaline conditions, with the pH-influenced samples exhibiting a more pronounced reduction in shear stress than those affected by seawater.

A Study on A Study on the University Education Plan Using ChatGPTfor University Students (ChatGPT를 활용한 대학 교육 방안 연구)

  • Hyun-ju Kim;Jinyoung Lee
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.1
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    • pp.71-79
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    • 2024
  • ChatGPT, an interactive artificial intelligence (AI) chatbot developed by Open AI in the U.S., gaining popularity with great repercussions around the world. Some academia are concerned that ChatGPT can be used by students for plagiarism, but ChatGPT is also widely used in a positive direction, such as being used to write marketing phrases or website phrases. There is also an opinion that ChatGPT could be a new future for "search," and some analysts say that the focus should be on fostering rather than excessive regulation. This study analyzed consciousness about ChatGPT for college students through a survey of their perception of ChatGPT. And, plagiarism inspection systems were prepared to establish an education support model using ChatGPT and ChatGPT. Based on this, a university education support model using ChatGPT was constructed. The education model using ChatGPT established an education model based on text, digital, and art, and then composed of detailed strategies necessary for the era of the 4th industrial revolution below it. In addition, it was configured to guide students to use ChatGPT within the permitted range by using the ChatGPT detection function provided by the plagiarism inspection system, after the instructor of the class determined the allowable range of content generated by ChatGPT according to the learning goal. By linking and utilizing ChatGPT and the plagiarism inspection system in this way, it is expected to prevent situations in which ChatGPT's excellent ability is abused in education.

A Design of an NCS-Based Job Matching System for the Disability

  • Jung-Youn Park;Min-Ji Kim;Jin-Ui Kim;Jin-Seop Yoo;Eun-Mi Mun;Hee-Young Nam;Won Joo Lee
    • Journal of the Korea Society of Computer and Information
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    • v.29 no.6
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    • pp.121-130
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    • 2024
  • In this paper, we propose and design an NCS-based job matching system for individuals with disabilities. This system allows users with disabilities to access it, input basic information (personal and disability-related details), and take a simple test related to job performance. The system then provides NCS job-related information appropriate to their type and degree of disability. To effectively link various NCS-based jobs, it is essential to consider the degree of disability for each type of disability. However, most evaluation tools target specific types of disabilities or assess the vocational abilities of individuals with disabilities in a limited manner, focusing only on cognitive levels or certain physical functions. This makes it challenging to apply these tools to an NCS-based job matching system for individuals with disabilities. Therefore, in this paper, we utilize the ICF coresets for VR to assess the cognitive levels or physical functions required for performing specific jobs. Additionally, we use the NCS vocational competency evaluation tools to determine the levels of vocational competencies required for performing specific jobs. By doing so, we match NCS-based jobs according to the type and degree of disability. The proposed NCS-based job matching system relies on the user's interaction with the system, which may pose challenges for visually impaired individuals or those with intellectual and autism spectrum disabilities who have low literacy levels. Enhancing the accessibility of this system could enable individuals with disabilities to receive recommendations for NCS-based jobs that suit their vocational abilities.

Undergraduate Students' Response Characteristics by Cognitive Conflict Levels and Result Predictions on Action-Reaction and Electric Cireuits Learning Tasks (작용 . 반작용과 전기회로 학습과제에서 인지갈등과 결과예측에 따른 대학생의 응답특성)

  • Hong, Jeon-Gin;Kim, Yeoun-Soo;Kwon, Jae-Sool
    • Journal of The Korean Association For Science Education
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    • v.27 no.4
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    • pp.354-365
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    • 2007
  • The purpose of this study was to understand the undergraduate students' response characteristics by their cognitive conflict levels and result predictions when they were confronted with the learning tasks of action & reaction and electric circuits. The 147 engineering college students who were enrolled at the introductory physics classes were selected as the subjects for this study. The students were grouped by cognitive levels and result predictions. First, in action and reaction task, the trend of suspecting experimental results and finding the reasons was dominant; however, in electric circuits, the trend of accepting the results was dominant. Second, the reasons for the responses on the subcategories of cognitive conflict were different by the level of cognitive conflict. The responses were influenced by students' preexisting knowledge, former experiences, learning habits, learning motivation, and epistemological beliefs, etc. The high conflict group recognized what they do not consider and was positive to reappraise their preconceptions, while the low conflict group showed the tendency of accepting the situation without doubt and low interest on learning physics. In conclusion, students responses showed differences in cognitive conflict levels, result predictions and presented conflict tasks. The research results, especially the response characteristics, suggest that more research on effective cognitive conflict strategies appropriate for different tasks and students' conflicts are necessary for effective physics teaching.

The Effect of Online Multiple Channel Marketing by Device Type (디바이스 유형을 고려한 온라인 멀티 채널 마케팅 효과)

  • Hajung Shin;Kihwan Nam
    • Information Systems Review
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    • v.20 no.4
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    • pp.59-78
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    • 2018
  • With the advent of the various device types and marketing communication, customer's search and purchase behavior have become more complex and segmented. However, extant research on multichannel marketing effects of the purchase funnel has not reflected the specific features of device User Interface (UI) and User Experience (UX). In this study, we analyzed the marketing channel effects of multi-device shoppers using a unique click stream dataset from global online retailers. We examined device types that activate online shopping and compared the differences between marketing channels that promote visits. In addition, we estimated the direct and indirect effects on visits and purchase revenue through customer's accumulated experience and channel conversions. The findings indicate that the same customer selects a different marketing channel according to the device selection. These results can help retailers gain a better understanding of customers' decision-making process in multi-marketing channel environment and devise the optimal strategy taking into account various device types. Our empirical analyses yield business implications based on the significant results from global big data analytics and contribute academically meaningful theoretical framework using an economic model. We also provide strategic insights attributed to the practical value of an online marketing manager.

A Study on the Extraction of Psychological Distance Embedded in Company's SNS Messages Using Machine Learning (머신 러닝을 활용한 회사 SNS 메시지에 내포된 심리적 거리 추출 연구)

  • Seongwon Lee;Jin Hyuk Kim
    • Information Systems Review
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    • v.21 no.1
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    • pp.23-38
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    • 2019
  • The social network service (SNS) is one of the important marketing channels, so many companies actively exploit SNSs by posting SNS messages with appropriate content and style for their customers. In this paper, we focused on the psychological distances embedded in the SNS messages and developed a method to measure the psychological distance in SNS message by mixing a traditional content analysis, natural language processing (NLP), and machine learning. Through a traditional content analysis by human coding, the psychological distance was extracted from the SNS message, and these coding results were used for input data for NLP and machine learning. With NLP, word embedding was executed and Bag of Word was created. The Support Vector Machine, one of machine learning techniques was performed to train and test the psychological distance in SNS message. As a result, sensitivity and precision of SVM prediction were significantly low because of the extreme skewness of dataset. We improved the performance of SVM by balancing the ratio of data by upsampling technique and using data coded with the same value in first content analysis. All performance index was more than 70%, which showed that psychological distance can be measured well.

Effect of Extraction Process on the Physicochemical Characteristics of Seed Oil of Camellia sinensis (추출 공정에 따른 Camellia sinensis 오일의 물리화학적 특성에 관한 연구)

  • Kim, Youn-Soon;Kim, Ran;Na, Myung-Soon;Choi, DuBok
    • Applied Chemistry for Engineering
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    • v.21 no.2
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    • pp.148-153
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    • 2010
  • This study was carried out to investigate the effect of extraction methods on the physicochemical characteristics using seed oil of wild green tea (Camellia sinensis). When the solvent extraction method after grinding and steam treatment (SGS) was used for oil extraction, the yield was highest. The specific gravity was a range of $0.91{\sim}0.94g/cm^{3}$ irrespective of extraction methods of oil. However, the light in the solvent extraction method after grinding (SG), the red in the pressure extraction method after grinding and roasting treatment (PGR), and the yellow in SG method were highest. Among various fatty acids, the concentrations of C16 : 0, C18 : 1 and C18 : 2 were highest, irrespective of extraction methods. Especially, the C16 : 0 concentration was in the order of SG (34.78%), SGS (23.04%), and PRGS method (23.01%), the C18 : 1 concentration was in the order of PGR (43.35%), SGS (42.7%), SG method (39.0%), and in the case of C18 : 2, it was in order of PGR (23.15%), SGS (23.03%), and SG method (15.01%). The saturated fatty acid concentration was in the order of SG (40.59%), PGR (31.61%), and SGS method (30.1%). On the other hand, in the case of the unsaturated fatty acid, it was in the order of SGS (69.9%), PGR (68.39%), and SG method (59.41%). The acid values in the SGS and SG method after 10 days of storage were in the range of 6~8 mgKOH/g. However, in the case of PGR method, it was increased with the increase of storage time and was 49.3 mgKOH/g after 60 days. The peroxide values in the SGS and SG method were in the range of 60~100 mEq/g from 10 to 60 days of storage. On the other hand, when the storage time was increased from 10 to 30 days, it was sharply increased from 60 to 240 mEq/g. The rancidity was in the order of $Fe^{2+}$, $Cu^{2+}$, $Cr^{2+}$, $Zn^{2+}$ and $Ni^{2+}$, irrespective of extraction methods. Especially, when butylated hydroxyanisole (BHA) was added into oil containing 1.0 ppm of <$Fe^{2+}$, the peroxide value was decreased from 539.4 to 216.6%. These results show that seed oil of Camellia sinensis grown in Iksan can be applied as sources for cosmetics, detergents, food, and pharmaceuticals.

Evaluation of Nutrient Discharges from Greenhouses with Flooding Soil Surface at Two Different Locations (입지조건이 다른 시설재배지에서 담수처리에 따른 양분 용탈량 평가)

  • Kim, Min-Kyeong;Roh, Kee-An;Ko, Byong-Gu;Park, Seong-Jin;Jung, Goo-Bok;Lee, Deog-Bae;Kim, Chul-Soo
    • Korean Journal of Soil Science and Fertilizer
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    • v.43 no.3
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    • pp.315-321
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    • 2010
  • Greenhouse soil cultivated with excessive compost and chemical fertilizer has been an issue to deteriorate soil and water quality in the environment. The objective of this study was to evaluate the nutrient outflow by desalting method, flooding soil surface, after vegetable cropping in greenhouse soils. Field experiment from July to September 2008, was conducted to quantify greenhouse locations, i.e. alluvial plain and local valley. The changes of desalinization in both locations were higher as the amounts of irrigated and drained water were increased. Particularly, the ratio of desalinization in alluvial plain was much higher (66.7%) than the one in local valley (45.6%). However, $NH_4$-N contents of local valley soil during the flooding were higher than in those of alluvial plain. This was caused by high total nitrogen and organic matter in local valley soil than those in alluvial plain soil. With comparing to the input and output loads of T-N and T-P in greenhouses with local valley and alluvial plain soils, the output loads of nutrients were larger than the input loads of nutrients. This result showed that the flooding soil surface can be a good treatment to desalinize greenhouse soils. However, this conclusion remained that the flooding water containing high N and P concentrations might cause the secondary effect on the quality of streams and groundwater since excessive nutrient concentrations can be the main cause of eutrophication problem in aquatic environment.

Iron, Manganese and Cadmium Contents of Sphalerites and their Genetical Implications to Hydrothermal Metallic Ore Deposits in Korea (국내산(國內産) 섬아연석(閃亞鉛石)의 Fe, Mn, Cd함량변화(含量變化)와 열수금속광상(熱水金屬鑛床) 성인(成因)과의 관련성(關聯性))

  • Chon, Hyo Taek;Shimazaki, Hidehiko
    • Economic and Environmental Geology
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    • v.19 no.spc
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    • pp.139-149
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    • 1986
  • Compositional variation of sphalerites from various hydrothermal metallic ore deposits in Korea were investigated in mine and local, and regional scale. The sphalerites were partially analyzed for iron, manganese, and cadmium by using an electron probe microanalyzer(EPMA). The contents of iron and cadmium in sphalerites collected from the Weolam deposit of the No.1 Yeonhwa mine are not variable with increase of depth, but manganese content is highly variable. Sphalerites from lead-zinc deposits which are geologically associated with hypabyssal and effusive activity are characterized by high manganese (more than 1.0 MnS mole %) and low cadmium contents (less than 0.5 CdS mole %). Relatively manganese rich sphalerites are found in the deposits where sphalerites are enriched in iron content. Variation of cadmium content is very limited compared with that of manganese content. Sphalerites from most tungsten and some gold-silver deposits are remarkably high in cadmium content, but most of base metal and iron deposits are low in cadmium content. Cadmium content in sphalerites which occur in the metallic ore deposits genetically associated with plutonic activity shows a tendency to high variation. Available amounts of cadmium in sphalerites could be originated from the initial enrichment during the magmatic and postmagmatic processes.

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