• 한국정보기술학회논문지
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• 제17권8호
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• pp.75-83
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• 2019

본 논문에서는 Median flow와 영상의 Depth 정보를 이용하여 산업 현장의 다양한 환경 조건에서 실시간 철근의 끝점 추적 및 검출이 가능한 방법을 제안한다. 영상의 Depth 정보에 Median filter, Binarization, Morphology, Blob의 알고리즘을 사용하여 2개의 철근 끝점을 검출하는 방법을 제안하였다. 실시간 철근 끝점 추적을 위해서는 Median flow의 알고리즘을 이용하여 철근의 움직임 방향과 위치 추적을 제안하였다. 그리고 Depth 영상에서 검출된 철근 끝점 좌표와 Median flow를 이용한 철근의 위치추적 좌표를 서로 비교하여 최종 위치 좌표를 결정하였다. 그 결과 기존 Median flow 방식만 적용하였을 때 75% 정도의 철근의 최종 위치 판단 성공률이 Depth의 철근 끝점 정보까지 활용하였을 때는 95%까지 추적 성공률이 높아졌다.

• 한국통신학회논문지
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• 제38C권12호
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• pp.1134-1149
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• 2013

Pub/sub 기술은 메시지 기반으로 데이터 생성자의 위치, 시간, 동기화 등에 대한 데이터에 제한 없이 접근할 수 있게 하는 특징을 가지므로, 데이터 중심 서비스를 위한 미들웨어 구축 기술로 널리 활용되고 있다. 국제 표준화 기구인 OMG (Object Management Group)에서 정의한 DDS (Data Distribution Service)는 pub/sub 기반의 미들웨어 기술로서, 미국 군용 장비의 표준 미들웨어로 채택되는 등 그 유용성이 높이 인정받고 있다. 그러나 publisher와 subscriber가 밀집된 환경에서는, 시스템 초기 부팅 시에 시스템 내 data 생산과 소비 주체가 되는 Participant와 Endpoint들을 탐색하는 과정에서의 지연 시간이 길다는 문제점을 갖고 있다. 본 논문에서는 지역적으로는 넓지 않지만 시스템 내의 Participant와 Endpoint의 수가 밀집된 환경에서의 탐색 시간을 줄일 수 있는 방안을 제시한다. 기존의 DDS 표준에서 정의하고 있는 표준 탐색 단계인 Participant 탐색 단계와 Endpoint 탐색 단계를 통합하고 분산 해쉬 기법의 Successor 개념을 도입하여 각 Participant마다 메시지를 전달해야 하는 대상의 수를 줄였다. 메시지 전달대상의 수를 줄임으로써 전송 프로토콜로 TCP를 적용하는 것이 가능해져, 메시지 전달의 신뢰성을 높일 수 있었다. 네트워크 시뮬레이터를 통한 성능 평가에서 본 연구에서 제안한 기법이 기존 기법에 비해 10%의 탐색 시간으로 시스템 내 Participant와 Endpoint를 발견할 수 있었다.

• 청정기술
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• 제23권1호
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• pp.27-33
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• 2017

본 연구에서는 중금속 7종(Cu, Cd, Cr, As(III), As(V), Zn, Ni) 및 나노입자 5종(CuO, ZnO, NiO, $TiO_2$, $Fe_2O_3$)에 대한 독성을 수계 대표 생물종인 녹조류 Chlorella vulgaris를 이용한 생물검정법으로 평가하였다. 조류에 미치는 영향은 흡광도, 클로로필 및 개체수 측정에 대한 결과를 통합하여 평가하였다. 중금속의 통합결과독성($TEC_{50}$) 순서는 Cr ($0.7mgL^{-1}$) > Cu ($1.7mgL^{-1}$) > Cd ($3.2mgL^{-1}$) > Zn ($3.9mgL^{-1}$) > Ni ($13.2mgL^{-1}$) > As(III) ($17.8mgL^{-1}$) ${\gg}$ As(V) (> $1000mgL^{-1}$)로 나타났다. 중금속은 측정종말점에 따라 일부 상이한 민감도와 독성이 조사되었다. 나노입자의 독성($TEC_{50}$) 순서는 ZnO ($2.4mgL^{-1}$) > NiO ($21.1mgL^{-1}$) > CuO ($36.6mgL^{-1}$) > $TiO_2$ ($62.5mgL^{-1}$) > $Fe_2O_3$ ($82.7mgL^{-1}$)로 나타났다. 나노입자는 측정종말점간에 비슷한 민감도와 독성을 보였다. 따라서 오염물의 독성을 평가하기 위해서 단일 방법에 의한 결과보다는 다양한 측정종말점의 통합결과에 근거한 접근이 적절할 것이다.

• 호남수학학술지
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• 제30권4호
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• pp.733-741
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• 2008

Let T be Gauss transformation on the unit interval defined by T (x) = ${\frac{1}{x}}$ where {x} is the fractional part of x. Gauss transformation is closely related to the continued fraction expansions of real numbers. We show that almost every x is mod M normal number of Gauss transformation with respect to intervals whose endpoints are rational or quadratic irrational. Its connection to Central Limit Theorem is also shown.

• 대한수학회보
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• 제45권3호
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• pp.563-571
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• 2008

We deduce the necessary conditions for the optimality of endpoint constrained optimal control problem. These conditions comprise the adjoint equation, the maximum principle and the transversality condition. We assume that the cost function is merely differentiable. Therefore the technique under Lipschitz continuity hypothesis is not directly applicable. We introduce Fermat's rule and value function technique to obtain the results.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.176-176
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• 2001

Endocrine disruptors have been implicated in carcinogenesis in animal studies, but carcinogenetic effects on human remain controversial. In order to examine the genotoxicity of two common endocrine disruptors, Bisphenol A and Diethylstilbestrol, cytogenetic endpoints including chromosome aberration(CA), sister chromatid exchange (SCE), micronuclei (MN) analyses and DNA damage by single cell gel electrophoresis (SCGE) were assayed.(omitted)

• 충청수학회지
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• 제23권3호
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• pp.463-470
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• 2010

If P(f, r) is the set of endpoints of radii which have length greater than or equal to r > 0 under a conformal mapping f of the unit disc. Then for large r, the logarithmic capacity of P(f, r), $\frac{1}{\sqrt[2]{r}}{\leq}cap(P(f,r)){\leq}\frac{k}{\sqrt{r}}$. Where k is the positive constant.

• IMMUNE NETWORK
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• 제15권2호
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• pp.83-90
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• 2015

Evaluation and screening of vaccines against tuberculosis depends on development of proper cost effective disease models along with identification of different immune markers that can be used as surrogate endpoints of protection in preclinical and clinical studies. The objective of the present study was therefore evaluation of subcutaneous model of M.tuberculosis infection along with investigation of different immune biomarkers of tuberculosis infection in BALB/c mice. Groups of mice were infected subcutaneously with two different doses : high ($2{\times}10^6CFU$) and low doses ($2{\times}10^2CFU$) of M.tuberculosis and immune markers including humoral and cellular markers were evaluated 30 days post M.tuberculosis infections. Based on results, we found that high dose of subcutaneous infection produced chronic disease with significant (p<0.001) production of immune markers of infection like $IFN{\gamma}$, heat shock antigens (65, 71) and antibody titres against panel of M.tuberculosis antigens (ESAT-6, CFP-10, Ag85B, 45kDa, GroES, Hsp-16) all of which correlated with high bacterial burden in lungs and spleen. To conclude high dose of subcutaneous infection produces chronic TB infection in mice and can be used as convenient alternative to aerosol models in resource limited settings. Moreover assessment of immune markers namely mycobacterial antigens and antibodies can provide us valuable insights on modulation of immune response post infection. However further investigations along with optimization of study protocols are needed to justify the outcome of present study and establish such markers as surrogate endpoints of vaccine protection in preclinical and clinical studies in future.

• BMB Reports
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• 제36권1호
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• pp.1-11
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• 2003

The causative role of polycyclic aromatic hydrocarbons (PAH) in human carcinogenesis is undisputed. Measurements of PAH-DNA adduct levels in easily accessible white blood cells therefore represent useful early endpoints in exposure intervention of chemoprevention studies. The successful applicability of DNA adducts as early endpoints depends on several criteria:i.adduct levels in easily accessible surrogate tissues should reflect adduct levels in target-tissues, ii. toxicokinetics and the temporal relevance should be properly defined.iii. sources of inter- and intra-individual variability must be known and controllable, and finally iv. adduct analyses must have advantages as compared to other markers of PAH-exposure. In general, higher DNA adduct levels or a higher proportion of subjects with detectable DNA adduct levels were found in exposed individuals as compared with non-exposed subjects, but saturation may occur at high exposures. Furthermore, DNA adduct levels varied according to changes in exposure, for example smoking cessation resulted in lower DNA adduct levels and adduct levels paralleled seasonal variations of air-pollution. Intra-individual variation during continuous exposure was low over a short period of time (weeks), but varied significantly when longer time periods (months) were investigated. Inter-individual variation is currently only partly explained by genetic polymorphisms in genes involved in PAH-metabolism and deserves further investigation. DNA adduct measurement may have three advantages over traditional exposure assessment: i. they can smooth the extreme variability in exposure which is typical for environmental toxicants and may integrate exposure over a longer period of time. Therefore, DNA adduct assessment may reduce the monitoring effort. ii. Biological monitoring of DNA adducts accounts for all exposure routes. iii. DNA adducts may account for inter-individual differences in uptake, elimination, distribution, metabolism and repair amongst exposed individuals. In conclusion, there is now a sufficiently large scientific basis to justify the application of DNA adduct measurement as biomarkers in exposure assessment and intervention studies. Their use in risk-assessment, however, requires further investigation.

• 한국물환경학회지
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• 제28권2호
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• pp.313-319
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• 2012

Various nanomaterials may flow into the aquatic ecosystem via production, use, and treatment processes. Especially, gold nanoparticles (AuNPs) were categorized as manufactured nanomaterials presented by the Organization for Economic Cooperation and Development Working Party on Manufactured Nanomaterials (OECD WPMN) in 2010. AuNPs have been used in medical area, however, they were reported to induce cytotoxicity and oxidative DNA damage, as well as down-regulation of the DNA repair gene in mice and human cell lines. In this study, the aquatic toxicity data of AuNPs and gold ions were collected, with the specific test methods analyzed with respect to the form and size of AuNPs, test species, exposure duration, and endpoints. Currently, aquatic toxicity data of AuNPs and gold ions have been presented in 14 studies including 4 fish, 6 crustacean, 2 green algae, and 2 macrophytes studies, as well as a further 8 studies including 4 fish, 4 crustacean, 1 platyhelminthes, and 1 green algae, respectively. The AuNPs were 0.8-100 nm in size, as gold nanoparticles, gold nanorod, glycodendrimer-coated gold nanoparticles, and amine-coated gold nanoparticles. The tested endpoints were the individual toxicities, such as mortality, malformation, reproduction inhibition, growth inhibition and genetic toxicity such as oxidative stress, gene expression, and reactive oxygen species formation. The accumulation of AuNPs was also confirmed in the various receptor organs. These results are expected to be useful in understanding the aquatic toxicity of AuNPs and gold ions, as well as being applicable to future toxicity studies on AuNPs.