• 대한수의학회지
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• 제32권4호
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• pp.523-529
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• 1992

아프리카발톱두꺼비(Xenopus laevis)의 위장췌내분비세포를 면역조직화학적으로 관찰하였던 바 5-HT면역반응세포들은 중등도로 전장관에 고루 분포하였다. Gas/CCK면역반응세포는 유문부 장선의 기저부와 십이지장 점막상피에서 출현하였다. 소수의 glucagon면역반응세포는 위저부에서 약하게 반응하였고, 췌장에서는 외분비부에서만 관찰되었다. 직장을 제외한 전장관과 췌도 주변부 및 외분비부에서 somatostatin면역반응세포가 관찰되었다. CGs와 insulin면역반응세포는 전장관에서 관찰할 수 없었다. 그러나 insulin세포는 췌도의 중앙부와 외분비부에서 단독으로 출현하였다.

• 기본간호학회지
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• 제2권2호
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• pp.229-237
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• 1995

The purpose of this study is to define requisite content of physiology for nursing education. This study classifies the subjects of physiology into 15 areas. The areas are cell and cell membrane, body fluid, nervous system, special sense, muscular system, blood, cardiovascular system, respiratory system, urinary system, digestive system, energy metabolism, body temperature, immune system, endocrine system, and reproductive system. Each subject area is further classified into subarea, resulting in a total of 194 subarea. The importance of each subarea is measured with a 3-point scale using a questionnaire. The subjects of this study were full-time professors teaching nursing in Korean universities. The analysis of the data collected from 68 respondents is as follows. 1. The areas of physiology necessary for nursing education in the order of importance are : body fluid, blood, endocrine, immune system, body temperature, urinary system, respiratory system, digestive system, reproductive system, energy metabolism, nervous system, cardiovascular system, cell and cell membrane, muscular system, and special sense. 2. Depending on the specific areas of nursing(such as pediatric nursing, maternity nursing), the importance of each physiology area may differ. For instance, the most important area for maternity nursing is reproductive physiology, whereas one for the psychiatric nursing is neuro-physiology. 3. The importance of each physiology area does not determine the importance of its subarea. For example, while the importance of cell and cell membrane was relatively very low across the respondents from different areas of nursing science, the importance of such subarea as osmosis, diffusion, and filteration reported by most respondents were high.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2001년도 춘계심포지움 및 학술발표회
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• pp.127-127
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• 2001

There is a concern that chemicals in our environment are affecting human health by disrupting a normal endocrine function. Much of the concern has focused on chemicals that can interact directly with steroid hormone receptors. The ability of certain man-made chemicals to mimic the effects of natural steroid hormones and their potential to disrupt the delicate balance of the endocrine system in animals are of increasing concern. (omitted)

• Environmental Analysis Health and Toxicology
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• 제16권4호
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• pp.197-204
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• 2001

Endocrine disruption in crucian carp (Carassius auratus) living in the branch of Han River were examined. Vitellogenin level in plasma was measured using ELISA system and aromatase mRNA level in brain was observed using RT-PCR technique. In all female fish, vitellogenin levels were in the range of 20∼40 $\mu\textrm{g}$/ml and aromatase mRNA expression could be detected on the agarose gel after RT-PCR. However, in case of males, vitellogenin level was elevated in only one fish, while vitellogenin was hardly detected in others. Aromatase was expressed in all males although the levels were relatively lower than the level in female fish. Testis-ova and any other histological changes of reproductive organ were not shown in both sexes.

• Clinical and Experimental Reproductive Medicine
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• 제39권1호
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• pp.1-9
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• 2012

The safety of human exposure to an ever-increasing number and diversity of electromagnetic field (EMF) sources both at work and at home has become a public health issue. To date, many in vivo and in vitro studies have revealed that EMF exposure can alter cellular homeostasis, endocrine function, reproductive function, and fetal development in animal systems. Reproductive parameters reported to be altered by EMF exposure include male germ cell death, the estrous cycle, reproductive endocrine hormones, reproductive organ weights, sperm motility, early embryonic development, and pregnancy success. At the cellular level, an increase in free radicals and $[Ca^{2+}]i$ may mediate the effect of EMFs and lead to cell growth inhibition, protein misfolding, and DNA breaks. The effect of EMF exposure on reproductive function differs according to frequency and wave, strength (energy), and duration of exposure. In the present review, the effects of EMFs on reproductive function are summarized according to the types of EMF, wave type, strength, and duration of exposure at cellular and organism levels.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.134.2-135
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• 2003

A large number of chemical pollutants including phthalates, alkylphenolic compounds, organochlorine pesticides and bisphenol A have the ability to disrupt endocrine function in animals. and alter cognitive function. Because hormone mediated events playa important role in central nervous system development and functions. The speculations that the changes in cognitive function are mediated by the endocrine-like action of these chemicals. (omitted)

• Asian-Australasian Journal of Animal Sciences
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• 제23권12호
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• pp.1668-1676
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• 2010

The somatotropic axis plays a key role in proliferation and differentiation of avian organs during both pre- and posthatching periods. This review discusses the complexity of regulation of the endocrine system for chicken development and growth by growth hormone (GH), insulin-like growth factor (IGF), and IGF binding protein (IGFBP). In addition, the thyrotropic axis, including thyrotropin-releasing hormone (TRH) and thyroid hormones ($T_4$ and $T_3$), is also involved in the GH-secreting pattern. In mammals, IGFI and -II are always sequestered in a 150 kDa non-covalent ternary complex. This complex consists of one molecule each of IGF-I or IGF-II, IGFBP-3 or IGFBP-5 and an acid labile subunit (ALS). Chick ALS is identified in different strains for the first time, and further investigation of the expression of ALS on developmental stage and ALS effect on IGF bioavailability may be addressed in the future.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2002년도 추계국제학술대회
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• pp.119-121
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• 2002

인류는 1,500 만 종류에 달하는 화학물질을 합성 혹은 분리ㆍ동정 해왔다. 그리고 현재 약 10 만 종류 정도의 화학물질이 상업적으로 이용되고 있다. 이들 화학물질 중에 유기염소화합물, 공업용화합물, 농약류, 유기취소(bromine)화합물, 중금속 및 유기금속, 식물 및 합성에스트로겐 등을 포함한 수십 종의 화합물이 내분비계장애물질 (Endocrine Disruptors, EDs)로서 생각, 혹은 의심되고 있다. 그러나, 대부분의 다른 화합물에 대해서는 그것들이 내분비계장애 작용을 가지고 있는지에 대한 충분한 지견이 얻어지지 않고 있어 이들 화학물질의 내분비계장애 작용을 평가하기 위해서는 신속 또는 간편한 검출계의 확립은 매우 중요하다.

• 환경생물
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• 제29권1호
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• pp.74-80
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• 2011

In this study we present a mammalian cell culture model that allows to study the effect of endocrine disruptors (EDCs) on aromatase activity of aquatic amphibian, Bombina orientalis. Bombina orientalis aromatase gene was subcloned into a mammalian expression vector and subsequently transfected to mammalian cells. Although the protein expression level of Bombina orientalis aromatase was low, it had a significant aromatase activity. When EDCs were added to aromatase transfected cells, aromatase activity was significantly decreased. We report here that this system may be used to monitor the effect of EDCs on aromatase activity of aquatic organisms.

• 보건교육건강증진학회지
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• 제18권2호
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• pp.115-128
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• 2001

This study was carried out to offer the basic data for more qualitative lives of the adulthood with obesity through their health maintenance and control. So, the researcher reviewed and analyzed the health problems of the subjects according to sex, age, and positive rate on the screening tests. The subjects were 91 obese persons in K university hospital in Seoul from December 1, 2000 to January 31, 2001. A Questionnaire developed by researcher to obtain subject's general characteristics, main symptoms, medical examination, diagnosed disease was used as the tool for the study. The results of this study are as follows: 1. For the distribution of diagnosis in subjects, liver disease was most frequent and hypertension was second. 2 The most common complaints were indigestion in the digestive system, throat pain in the respiratory system, dyspnea in cardiovascular system, thirsty in endocrine system, frequent urine in the urinary system, vertigo in the hematologic system. 3. The main symptoms according to sex were for females, a statistically significant higher rate of complaints in the digestive system, musculoskeletal system as compared to males. 4. The main symptoms according to age were that in the fourth decade there were higher rate of complaints in the musculoskeletal system. 5. In screening tests according to sex, males showed a higher positive rate for Alk-Phosphatase and females, in FBS, urine-micro, VDRL. 6. In screening tests according to age, higher positive rates of BP, Chest X-ray, mammography, ESR, CRP were seen in the fourth decades. 7. Obesity was positively related to cardiovascular system, endocrine system, urinary system, musculoskeletal system, mental and nervous system in main symptoms. 8. Obesity was positively related to BP, Sonography, FBS, SGOT, SGPT in screening tests.