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http://dx.doi.org/10.5713/ajas.2010.10329

The Endocrine Regulation of Chicken Growth  

Kim, Jin-Wook (Department of Animal Bioscience, College of Agriculture and Life Sciences (Inst. of Agric. and Life Sci.), Gyeongsang National University)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.23, no.12, 2010 , pp. 1668-1676 More about this Journal
Abstract
The somatotropic axis plays a key role in proliferation and differentiation of avian organs during both pre- and posthatching periods. This review discusses the complexity of regulation of the endocrine system for chicken development and growth by growth hormone (GH), insulin-like growth factor (IGF), and IGF binding protein (IGFBP). In addition, the thyrotropic axis, including thyrotropin-releasing hormone (TRH) and thyroid hormones ($T_4$ and $T_3$), is also involved in the GH-secreting pattern. In mammals, IGFI and -II are always sequestered in a 150 kDa non-covalent ternary complex. This complex consists of one molecule each of IGF-I or IGF-II, IGFBP-3 or IGFBP-5 and an acid labile subunit (ALS). Chick ALS is identified in different strains for the first time, and further investigation of the expression of ALS on developmental stage and ALS effect on IGF bioavailability may be addressed in the future.
Keywords
Chicken; Growth; GH; IGF-I; IGFBP; ALS;
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1 Vanderpooten, A., L. M. Huybrechts, P. Rudas, E. Decuypere and E. R. Kuhn. 1991a. Differences in hepatic growth hormone receptor binding during development of normal and dwarf chickens. Reprod. Nutr. Dev. 31:47-55.   DOI   ScienceOn
2 Vanderpooten, A., V. M. Darras, L. M. Huybrechts, P. Rudas, E. Decuypere and E. R. Kuhn. 1991b. Effect of hypophysectomy and acute administration of growth hormone (GH) and GHreceptor binding in chick liver membranes J. Endocrinol. 129:275-281.   DOI   ScienceOn
3 Scanes, C. G., D. R. Duyka, T. J. Lauterio, S. J. Bowen, L. M. Huybrechts, W. L. Bacon and D. B. King. 1986. Effect of chicken growth hormone, triiodothyronine and hypophysectomy in growing domestic fowl. Growth 50:12-31.
4 Scanes, C. G., J. Marsh, E. Decuypere and P. Rudas. 1983. Abnormalities in the plasma concentrations of thyroxine, triiodothyronine and growth hormone in sex-linked dwarf and autosomal White Leghorn domestic fowl (Gallus domesticus). J. Endocrinol. 97:127-135.   DOI   ScienceOn
5 Serrano, J., A. R. Shuldiner, C. T. Roberts, D. LeRoith and F. De Pablo. 1990. The insulin-like growth factor (IGF-I) gene is expressed in chick embryos during early organogenesis. Endocrinology 127:1547-1549.   DOI   ScienceOn
6 Tanaka, M., Y. Hayashida, K. Sakaguchi, T. Ohkubo, M. Wakita, S. Hoshino and K. Nakashima. 1996. Growth hormoneindependent expression of insulin-like growth factor I messenger ribonucleic acid in extrahepatic tissues of the chicken. Endocrinology 137:30-34.   DOI   ScienceOn
7 Thommes, R. C., J. B. Martens, W. E. Hopkins, J. Caliendo, M. J. Sorrentino and J. E. Woods. 1983. Hypothalamoadenohypophyseal- thyroid interrelationships in the chick embryo. IV. Immunocytochemical demonstration of TSH in the hypophyseal pars distalis. Gen. Comp. Endocrinol. 51:434-443.   DOI   ScienceOn
8 Tixier-Boichard, M., L. M. Huybrechts, E. Becuypere, E. R. Kuhn, J. L. Monvoisin, G. Coquerelle, J. Charrier and J. Simon. 1992. Effects of insulin-like growth factor I (IGF-I) infusion and dietary tri-iodothyronine (T3) supplementation on growth, body composition and plasma hormone levels in sex-linked dwarf mutant and normal chickens. J. Endocrinol. 133:101-110.   DOI   ScienceOn
9 Tomas, F. M., R. A. Pym, J. P. McMurtry and G. L. Francis. 1998. Insulin-like growth factor (IGF)-I but not IGF-II promotes lean growth and feed efficiency in broiler chickens. Gen. Comp. Endocrinol. 110:-275.
10 Porter, T. E. 2005. Regulation of pituitary somatotroph differentiation by hormones of peripheral endocrine gland. Domest. Anim. Endocrinol. 29:52-62.   DOI   ScienceOn
11 Porter, T. E., G. S. Couger, C. E. Dean and B. M. Hargis. 1995. Ontogeny of growth hormone (GH)-secreting cells during chicken embryonic development: initial somatotrophs are responsive to GH-releasing hormone. Endocrinol. 136:1850-1856.   DOI   ScienceOn
12 Proudman, J. A., M. C. McGuinness, K. A. Krishnan and L. A. Cogburn. 1994. Endocrine and metabolic responses of intact and hypophysectomized turkey poults given a daily injection of chicken growth hormone. Comp. Biochem. Physiol. 109C:47-56.
13 Radecki, S. V., M. C. Capdevielle, F. C. Buonomo and C. G. Scanes. 1997. Ontogeny of insulin-like growth factor (IGF-I and IGF-II) and IGF-binding proteins in the chicken following hatching. Gen. Comp. Endocrinol. 107:109-117.
14 Rhoads, R. P., P. L. Greenwood, A. W. Bell and Y. B. Boisclair. 2000. Organization and regulation of the gene encoding the sheep acid-labile subunit of the 150-kilodalton insulin-like growth factor-binding protein complex. Endocrinology 141:1425-1433.   DOI   ScienceOn
15 Mohan, S. and D. J. Baylink. 2002. IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms. J. Endocrinol. 175:19-31.   DOI   ScienceOn
16 Rosebrough, R. W. and J. P. McMurtry. 2003. Methimazole and thyroid hormone replacement in broilers. Domest. Anim. Endocrinol. 24:231-242.   DOI   ScienceOn
17 Rosselot, G., J. P. McMurtry, R. Vasilatos-Younken and S. Czerwinski. 1995. Effect of exogenous chicken growth hormone (cGH) administration on insulin-like growth factor-I (IGF-I) gene expression in domestic fowl. Mol. Cell. Endocrinol. 114:157-166.   DOI   ScienceOn
18 Scanes, C. G. 2009. Perspectives on the endocrinology of poultry growth and metabolism. Gen. Com. Endocrinol. 163:24-32.   DOI   ScienceOn
19 Moore, G. E., S. Harvey, H. Klandorf and G. Goldspink. 1984. Muscle development in thyroidectomized chickens (Gallus domesticus). Gen. Comp. Endocrinol. 55:195-199.   DOI   ScienceOn
20 Morishita, D., M. Sasaki, M. Wakita and S. Hoshino. 1996. Effect of fasting on serum insulin-like growth factor-I (IGF-I) levels and IGF-binding activity in cockerels. J. Mol. Endocrinol. 139:363-370.
21 Morishita, D., M. Wakita and S. Hoshino. 1993. Effect of hypophysectomy on insulin-like growth factor (IGF)-I binding activity of serum in chickens. Comp. Biochem. Physiol. 104A:261-265.
22 Oldham, E. R., B. Bingham and W. R. Baumbach. 1993. A functional polyadenylation signal is embedded in the coding region of chicken growth hormone receptor RNA. Mol. Endocrinol. 7:1379-1390.   DOI   ScienceOn
23 Leong, S. R., R. C. Baxter, T. Camerato, J. Dai and W. I. Wood. 1992. Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex. Mol. Endocrinol. 6:870-876.   DOI   ScienceOn
24 O'Neill, I. E., B. Houston and C. Goddard. 1990. Stimulation of insulin-like growth factor I production in primary cultures of chicken hepatocytes by chicken growth hormone. Mol. Cell. Endocrinol. 70:41-47.   DOI   ScienceOn
25 Ooi, G. T., K. R. Hurst, M. N. Poy, M. M. Rechler and Y. B. Boisclair. 1998. Binding of STAT5a and STAT5b to a single element resembling a gamma- interferon-activated sequence mediates the growth hormone induction of the mouse acidlabile subunit promoter in liver cells. Mol. Endocrinol. 12:675- 687.   DOI   ScienceOn
26 Piper, M. M. and T. E. Porter. 1997. Responsiveness of chicken embryonic somatotrophs to somatostatin (SRIF) and IFG-I. J. Endocrinol. 154:303-310.   DOI   ScienceOn
27 Leung, F. C., J. E. Taylor and A. Van Iderstine. 1984. Effects of dietary thyroid hormones on growth and serum T3, T4 and growth hormone in sex-linked dwarf chickens. Proc. Soc. Exp. Biol. Med. 177:77-81.   DOI
28 Lu, F. Z., Z. Y. Jiang, X. X. Wang, Y. H. Luo, X. F. Li and H. L. Liu. 2010. Role of the insulin-like growth factor system in epiphyseal cartilage on the development of Langshan and Arbor Acres chickens, Gallus domesticus. Poult. Sci. 89:956-965.   DOI   ScienceOn
29 Mao, J. N., L. A. Cogburn and J. Burnside. 1997. Growth hormone down-regulates growth hormone receptor mRNA in chickens but developmental increases in growth hormone receptor mRNA occur independently of growth hormone action. Mol. Cell. Endocrinol. 129:135-143.   DOI   ScienceOn
30 Marsh, J. A., T. J. Lauterio and C. G. Scanes. 1984. Effects of triiodothyronine treatments on body and organ growth and the development of immune function in dwarf chickens. Proc. Soc. Exp. Biol. Med. 177:82-91.   DOI
31 McCann-Levorse, L. M., S. V. Radecki, D. J. Donoghue, S. Malamed, D. N. Foster and C. G. Scanes. 1993. Ontogeny of pituitary growth hormone and growth hormone mRNA in the chicken. Proc. Soc. Exp. Biol. Med. 202:109-113.   DOI
32 McGuinness, M. C. and L. A. Cogburn. 1990. Measurement of developmental changes in plasma insulin-like growth factor-I levels of broiler chickens by radioreceptor assay and radioimmunireceptor assay. Gen. Comp. Endocrinol. 79:446-458.   DOI   ScienceOn
33 McMurtry J. P., G. L. Francis and Z. Upton. 1997. Insulin-like growth factors in poultry. Dom. Anim. Endocrinol. 14:199-229.   DOI   ScienceOn
34 Kuhn, E. R., L. M. Huybrechts, A. Vanderpooten and L. Berghman. 1989. A decreased capacity of hepatic growth hormone (GH) receptors and failure of thyrotrophin-releasing hormone to stimulate the peripheral conversion of thyroxine into triiodothyronine in sex-linked dwarf broiler hens. Reprod. Nutr. Dev. 29:461-467.   DOI
35 Kuhn, E. R., L. Vleurick, M. Edery, E. Decuypere and V. M. Darras. 2002. Internalization of the chicken growth hormone receptor complex and its effect on biological functions. Com. Biochem. Physiol. 132:299-308.   DOI   ScienceOn
36 Kuhn, E. R., S. M. E. Geelissen, S. Van der Geyten and V. M. Darras. 2005. The release of growth hormone (GH): releation to the thyrotrophic- and Corticotropic axis in the chicken. Domest. Anim. Endocrinol. 29:43-51.   DOI   ScienceOn
37 Lee, C. Y., I. Kwak, C. S. Chung, W. S. Choi, R. C. Simmen and F. A. Simmen. 2001. Molecular cloning of the porcine acid-labile subunit (ALS) of the insulin-like growth factor-binding protein complex and detection of ALS gene expression in hepatic and non-hepatic tissues. J. Mol. Endocrinol. 26:135-144.   DOI   ScienceOn
38 Lazarus, D. D. and C. G. Scanes. 1988. Acute effects of hypophysectomy and administration of pancreatic and thyroid hormones on circulating concentrations of somatomedin-C and young chickens: relationship between growth hormone and somatomedin-C. Domest. Anim. Endocrinol. 5:283-289.   DOI   ScienceOn
39 Leach, R. M. and G. E. Rosselot. 1992. The use of avian epiphyseal chondrocytes for in vitro studies of skeletal metabolism. J. Nutr. 122:802-805.
40 Leach, R. M., M. P. Richards, C. A. Praul, B. C. Ford and J. P. McMurtry. 2006. Investigation of the insulin-like growth factor system in the avian epiphyseal growth plate. Domest. Anim. Endocrinol. 33:143-153.
41 Kikuchi, K., F. C. Buonomo, Y. Kajimoto and P. Rotwein. 1991. Expression of insulin-like growth factor-I during chicken developemnt. Endocrinology 128:1323-1328.   DOI   ScienceOn
42 Kim, J. W. and Y. R. Boisclair. 2008. Growth hormone signaling in the regulation of acid labile subunit. Asian-Aust. J. Anim. Sci. 21:754-768.   과학기술학회마을   DOI
43 Kim, J. W., R. P. Rhoads, N. Segoale, N. B. Kristensen, D. E. Bauman and Y. B. Boisclair. 2006. Isolation of the cDNA encoding the acid labile subunit (ALS) of the 150 kDa IGFbinding protein complex in cattle and ALS regulation during the transition from pregnancy to lactation. J. Endocrinol. 189:583-593.   DOI   ScienceOn
44 Kita, K., K. Nagao, N. Taneda, Y. Inagaki, K. Hirano, T. Shibata, M. A. Yaman, M. A. Conlon and J-I. Okumura. 2002. Insulinlike growth factor binding protein-2 gene expression can be regulated by diet manipulation in several tissues of young chickens. J. Nutr. 132:145-151.
45 King, D. B. and C. R. King. 1973. Thyroidal influence on early muscle growth chickens. Gen. Comp. Endocrinol. 21:517-529.   DOI   ScienceOn
46 King, D. B. and C. R. King. 1976. Thyroidal influence on gastrocinemus and sartorius muscle growth in young White Leghorn cockerels. Gen. Comp. Endocrinol. 29:473-479.   DOI   ScienceOn
47 Kita, K., F. M. Tomas, P. C. Owen, S. E. Knowles, B. E. Forbes, Z. Uptons, R. Hughes and F. J. Ballard. 1996. Influence of nutrition on hepatic IGF-I mRNA levels and plasma concentration of IGF-I and IGF-II in meat-type chickens. J. Endocrinol. 149:181-190.   DOI   ScienceOn
48 Kuhn, E. R. 1993. Role of growth hormone in thyroid function of vertebrates. Academiae Analecta 55:3-13.
49 Haselbacher, G. K., R. Y. Andres and R. E. Humbel. 1980. Evidence for the synthesis of a somatomedin similar to insulinlike growth factor I by chick embryo liver cells. Eur. J. Biochem. 111:245-250.
50 Holzenberger, M., F. Lapointe, M. Leibovici and C. Ayer-Le Lievre. 1996. The avian IGF type I receptor: cDNA analysis and in situ hybridization reveal conserved sequence elements and expression patterns relevant for the development of the nervous system. Dev. Brain Res. 97:76-87.   DOI   ScienceOn
51 Huybrechts, L. M., E. Decuypere, C. G. Scanes, P. Callewaert, E. Peys and E. R. Kuhn. 1985. Human pancreatic growth hormone releasing factor stimulates growth hormone secretion in perinatal dwarf and control chickens. Horm. Metab. Res. 17:690-691.   DOI
52 Kallincos, N. C., J. C. Wallace, G. L. Francis and F. J. Ballard. 1990. Chemical and biological characterization of chicken insulin-like growth factor-II. J. Endocrinol. 124:89-97.   DOI   ScienceOn
53 Huybrechts, L. M., R. Michielsen, V. M. Darras, F. C. Buonomo, E. R. Kuhn and E. Decuypere. 1989. Effect of the sex-linked dwarf gene on thyrotropic and somatotropic axes in the chick embryo. Reprod. Nutr. Dev. 29:219-226.   DOI
54 Janosi, J. B., P. A. Ramsland, M. R. Mott, S. M. Firth, R. C. Baxter and P. J. Delhanty. 1999. The acid-labile subunit of the serum insulin-like growth factor-binding protein complexes. Structural determination by molecular modeling and electron microscopy. J. Biol. Chem. 274:23328-23332.   DOI
55 Johnson, R. J., J. P. McNurtry and F. J. Ballard. 1990. Ontogeny and secretory patterns of plasma insulin-like growth factor-I concentrations in meat-type chickens. J. Endocrinol. 124:81-87.   DOI   ScienceOn
56 Duclos, M. J. and C. Goddard. 1990. Insulin-like growth factor receptor in chicken liver membranes: Binding properties, specificity, developmental pattern and evidence for a single receptor type. J. Endocrinol. 125:199-206.   DOI   ScienceOn
57 Duclos, M. J., R. S. Wilkie and C. Goodard. 1991. Stimulation of DNA synthesis in chicken muscle satellite cells by insulin and insulin-like growth factors: evidence for exclusive mediation by a type-I insulin-like growth factor receptor. J. Endocrinol. 128:35-42.   DOI   ScienceOn
58 Edens, A. and F. Talamantes. 1998. Alternative processing of growth hormone receptor transcripts. Endocr. Rev. 19:559-582.   DOI   ScienceOn
59 Frawley, L. S., J. P. Hoeffler and F. R. Boockfor. 1985. Functional maturation of somatotropes in fetal rat pituitaries: analysis by reverse hemolytic plaque assay. Endocrinology 116:2355-2360.   DOI   ScienceOn
60 Firth, S. M., U. Ganeshprasad and R. C. Baxter. 1998. Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3. J. Biol. Chem. 273:2631-2638.   DOI   ScienceOn
61 Geris, K. L., L. R. Berghman, E. R. Kuhn and V. M. Darras. 1998. Pre- and post-hatch developmental changes in hypothalamic thytrotropin-releasing hormone and somatostatin concentrations and in circulating growth hormone and thyrotropin levels in the chicken. J. Endocrinol. 219-225.
62 Goddard, C., R. S. Wilkie and I. C. Dunn. 1988. The relationship between insulin like growth factor-I, growth hormone, thyroid hormones, and insulin in chickens selected for growth. Domest. Anim. Endocrinol. 5:165-176.   DOI   ScienceOn
63 Harvey, S., T. F. Davidson and A. Chadwick. 1979. Ontogeny of growth hormone and prolactin secretion in the domestic fowl (Gallus Domesticus). Gen. Com. Endocrinol. 39:270-273.   DOI   ScienceOn
64 Cynober, L., C. Aussel, P. Chatelian, M. Vaubourdolle, J. Agneray and O. G. Ekindjian. 1985. Insulin-like growth factor I/somatomedin C action on 2-deoxyglucose and a-amino isobutyrate uptake in chick embryo fibroblasts. Biochimie 67:1185-1190.   DOI   ScienceOn
65 Dai, J. and R. C. Baxter. 1992. Molecular cloning of the acidlabile subunit of the rat insulin-like growth factor binding protein complex. Biochem. Biophys. Res. Commun. 188:304-209.   DOI   ScienceOn
66 Dean, C. E., M. Piper and T. E. Porter. 1997. Differential responsiveness of somatotrophs to growth hormone-releasing hormone and thyrotropin-releasing hormone during chicken embryonic development. Mol. Cell. Endocrinol. 132:33-41.   DOI   ScienceOn
67 Dai, J. and R. C. Baxter. 1994. Regulation in vivo of the acid-labile subunit of the rat serum insulin-like growth factor-binding protein complex. Endocrinology 135:2335-2341.   DOI   ScienceOn
68 Darras, V. M., M.-F. Finne, L. R. Berghman and E. R. Kuhn. 1994. Ontogrny of the sensitivity of the somatotrophs to TRH and growth hormone-releasing factor (GRF) in the embryonic and post-hatch chick. Ann d'Endocrinol (Paris) 55:255-260.
69 Daughaday, W. H., M. Kapadia, C. E. Yanow, K. Fabrick and I. K. Mariz. 1985. Insulin-like growth factor I and IGF II of nonmammalian sera. Gen. Comp. Endocrinol. 59:316-325.   DOI   ScienceOn
70 De Groef, B., S. V. H. Grommen and V. M. Darras. 2008. The chicken embryo as a model for developmental endocrinology; development of the thyrotropic, corticotropic and somatotropic axes. Mol. Cell. Endocrinol. 293:17-24.   DOI   ScienceOn
71 De Pablo, F., V. B. Perez, J. Serna and G. P. R. Gonzalez. 1993. IGF-I and the IGF-I receptor in development of nonmammalian vetebrates. Mol. Reprod. Dev. 35:427-432.   DOI   ScienceOn
72 Butler, J. H. and P. D. Gluckman. 1986. Circulating insulin-like growth factor-binding proteins in fetal, neonatal and adult sheep. J. Endocrinol. 109:333-338.   DOI   ScienceOn
73 Butterwith, S. C. and C. Goddard. 1991. Regulation of DNA synthesis in chicken adipocyte precursor cells by insulin-like growth factors, platelet-derived growth factor and transforming growth $factor-{beta}$. J. Endocrinol. 131:203-209.   DOI   ScienceOn
74 Cogburn, L. A., J. Burnside and C. G. Scanes. 2000. Physiology of growth and development. Sturkie's avian physiology (5th ed.). Academic press.
75 Caldes, J., J. Alemany, H. L. Robcis and F. De Pablo. 1991. Expression of insulin-like growth factor I in developing lens is compartmentalized. J. Biol. Chem. 266:20786-20790.
76 Chin, E., J. Zhou, J. Dai, R. C. Baxter and C. A. Bondy. 1994. Cellular localization and regulation of gene expression for components of the insulin-like growth factor ternary binding protein complex. Endocrinology 134:2498-2504.   DOI   ScienceOn
77 Cogburn, L. A. 1991. Endocrine manipulation of body composition in broiler chicken. Cirt. Rev. Poult. Biol. 3:283-305.
78 Cogburn, L. A., N. C. Mao, S. Agarwal and J. Burnside. 1995. Interaction between somatotropic and thyrotropic axes in regulation of growth and development of broiler chickens. Arch. Geflugel. Sonderch. 1:18-21.
79 Cogburn, L. A., S. S. Liou, A. L. Rand and J. P. McMurtry. 1989. Growth, metabolic and endocrine responses of broiler cockerels given a daily subcutaneous injection of natural or biosynthetic chicken growth hormone. J. Nutr. 119:1213-1222.
80 Conlon, M. A. and L. Kita. 2002. Muscle protein synthesis rate is altered in response to a single injection of insulin-like growth factor-I in seven-day-old Leghorn chicks. Poult. Sci. 81:1543-1547.   DOI
81 Ballard, F. J., R. J. Johnson, P. C. Owen, G. L. Francis, F. M. Upton, J. P. McMurtry and J. C. Wallace. 1990. Chicken insulin-like growth factor-I: Amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79:459-468.   DOI   ScienceOn
82 Burch, W. M. and H. E. Lebovitz. 1982. Triiodothyronine stimulation of in vitro growth and maturation of embryonic chick cartilage. Endocrinology 111:462-468.   DOI   ScienceOn
83 Bassas, L., F. De Pablo, M. A. Lesniak and J. Roith. 1987. The insulin receptors of chick embryo show tissue specific structural differences which parallel those of the insulin -like growth factor-I receptors. Endocrinology 121:1468-1476.   DOI   ScienceOn
84 Binoux, M. and P. Hossenlopp. 1988. Insulin-like growth factor (IGF) and IGF-binding proteins: comparison of human serum and lymph. J. Clin. Endocrinol. Metab. 67:509-514.   DOI
85 Boisclair, Y. R., D. Seto, S. Hsieh, K. R. Hurst and G. T. Ooi. 1996. Organization and chromosomal localization of the gene encoding the mouse acid labile subunit of the insulin-like growth factor binding complex. Proc. Natl. Acad. Sci. USA 93:10028-10033.   DOI
86 Burch, W. M. and J. J. Van Wyk. 1987. Triiodothyronine stimulates cartilage growth and maturation by different mechamism. Am. J. Physiol. 252:E176-182.
87 Burnside, J. and L. A. Cogburn. 1992. Developmental expression of hepatic growth hormone receptor and insulin-like growth factor-I mRNA in the chicken. Mol. Cell. Endocrinol. 89:91-96.   DOI   ScienceOn
88 Burnside, J., S. S. Liou and L. A. Cogburn. 1991. Molecular cloning of the chicken growth receptor complementary deoxyribonucleic acid: mutation of the gene in sex-linked dwarf chickens. Endocrinology 128:3183-3192.   DOI   ScienceOn
89 Armstrong, D. G. and C. O. Hogg. 1994. Type-I insulin like growth factor receptor gene expression in the chick: Developmental changes and the effect of selection for increased growth on the amount of receptor mRNA. J. Mol. Endocrinol. 12:3-12.   DOI   ScienceOn
90 Agarwal, S. K., L. A. Cogburn and J. Burnside. 1994. Dysfunctional growth hormone receptor in a strain of sexlinked dwarf chicken: evidence for mutation in the intracellular domain. J. Endocrinol. 142:427-434.   DOI   ScienceOn
91 Zhou, M., Z. Ma and W. S. Sly. 1995. Cloning and expression of the cDNA of the chicken cation-independent-6-phosphate receptor. Proc. Natl. Acad. USA 92:9762-9766.   DOI
92 Yang, Y. W. H., D. R. Brown, H. L. Robcis, M. M. Rechler and F. De Pablo. 1993. Developmental regulation of insulin-like growth factor binding protein-2 in chick embryo serum and vitreous humor. Regul. Pept. 48:145-155.   DOI   ScienceOn
93 Yun, J. S., D. S. Seo, W. K. Kim and Y. Ko. 2005. Expression and relationship of the insulin-like growth factor system with posthatch growth in the Korea Native Ogol chicken. Poult. Sci. 84:83-90.   DOI
94 Zapf, J., C. Hauri, M. Waldvogel and E. R. Froesch. 1986. Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats. J. Clin. Invest. 77:1768-1775.   DOI   ScienceOn
95 Vasilatos-Younken, R., X. H. Wang, Y. Zhou, J. R. day, J. P. McNurtry, R. W. Rosenbrough, E. Decuypere, N. Buys, V. Darras, J. L. Beard and F. Tomas. 1999. New insights into the mechanism and actions of growth hormone (GH) in poultry. Domest. Anim. Endocrinol. 17:181-190.   DOI   ScienceOn
96 Vanderpooten, A., W. Janssens, J. Buyse, F. Leenstra, L. Berghman, E. Decuypere and E. R. Kuhn. 1993. Study of the hepatic growth hormone (GH) receptor at different ages in chickens selected for a good feed converson (FC) and a fast weight gain (GL.) Dom. Anim. Endocrinol. 10:199-206.   DOI   ScienceOn
97 Vasilatos-Younken, R., K. S. Gray, W. L. Bacon, K. E. Nestor, D. W. Long and J. L. Rosenberger. 1990. Ontogeny of growth hormone (GH) binding in the domestic turkey:evidence of sexual dimorphism and developmental changes in relationship to plasma GH. J. Endocrinol. 126:131-139.   DOI   ScienceOn
98 Vasilatos-Younken, R., T. L. Cravener, L. A. Cogburn, M. G. Mast and R. H. Wellenreiter. 1988. Effect of pattern of administration on the response to exogenous, pituitary-derived chicken growth hormone by broiler-strain pullets. Gem. Comp. Endocrinol. 71:268-283.   DOI   ScienceOn
99 Wilson, D. M. and R. L. Hintz. 1982. Inter-species comparison of somatomedin structure using immunological probes. J. Endocrinol. 95:59-64.   DOI   ScienceOn
100 Woelfle, J. and P. Rotwein. 2004. In vivo regulation of growth hormone-stimulated gene transcription by STAT5b. Am. J. Physiol. Endocrinol. Metab. 286:E393-401.
101 Yang, Y. W. H., A. R. Robbins, S. P. Nissley and M. M. Rechler. 1991. The chick embryo fibroblast cation-independent mannose 6-phosphate receptor is functional and immunologically related to the mammalian insulin-like growth factor-II (IGF-II)/man 6-p receptor but does not bind IGF-II. Endocrinology 128:1177-1189.   DOI   ScienceOn
102 Tsukada, A., T. Ohkubo, K. Sakaguchi, M. Tanaka, K. Nakashima, Y. Hayashida, M. Wakita and S. Hoshino. 1998. Thyroid hormones are involved in insulin-like growth factor-I (IGF-I) production by stimulating hepatic growth hormone receptor (GHR) gene expression in the chicken. Growth Horm. IGF Res. 8:235-242.   DOI   ScienceOn
103 Twigg, S. M. and R. C. Baxter. 1998. Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit. J. Biol. Chem. 273:6074-6079.   DOI   ScienceOn
104 Twigg, S. M., M. C. Kiefer, J. Zapf and R. C. Baxter. 1998. Insulin-like growth factor-binding protein 5 complexes with the acid-labile subunit. Role of the carboxyl-terminal domain. J. Biol. Chem. 273:28791-28798.   DOI
105 Ueki, I, S. L. Giesy, K. J. Harvatine, J. W. Kim and Y. R. Boisclair. 2009. The acid-labile subunit is required for full effects of exogenous growth hormone on growth and carbohydrate metabolism. Endocrinology 150:3145-3152.   DOI   ScienceOn
106 Ueki, I., G. T. Ooi, M. L. Tremblay, K. R. Hurst, L. A. Bach and Y. B. Boisclair. 2000. Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system. Proc. Natl. Acad. Sci. USA 97:6868-6873.   DOI   ScienceOn