• Korean Journal of Plant Taxonomy
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• v.42 no.3
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• pp.197-201
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• 2012

A new species, Elsholtzia byeonsanensis M. Kim is named and described from Byeonsan, Jeollabukdo Province, Korea. Molecular data confirmed that this new taxon was distinguished from other congeneric species. Elsholtzia byeonsanensis shares several characteristics (secund spikes, ovate leaves, long corolla length, etc.) with its related species E. splendens, but it is distinct from E. splendens which has a large plant, green stem color, chartaceous leaf textures, non-shiny leaf surfaces, pubescent petioles, pubescent leaf blade surfaces, pubescent bract surface, and open woodland habitats by having a small plant, purple stem color, coriaceous leaf textures, shiny leaf surfaces, glabrous petioles, glabrous leaf blade surfaces, glabrous bract surface, and marine habitats.

• Korean Journal of Plant Taxonomy
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• v.36 no.4
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• pp.309-333
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• 2006

Examined were the vegetative and reproductive characters such as external morphology, anatomy (leaf petiole, blade and stem), pollen and nutlet for the taxonomic revision of Elsholtzia in Korea. The inflorescence of all studied taxa of Elsholtzia in Korea is secund and 0.5-10 cm long. Leaves are ovate or nearly and $0.2-10{\times}0.2-6.0cm$. The shapes of inflorescence and leaves are very useful taxonomic characters. The stomata types are anomocytic and diacytic. The morphology of nutlet is ovoid and pitted in surface pattern of exocarp. All studied taxa are myxocarpy. The pollen grains are of medium size and subprolate in shape, and have typical bi-reticulate exine surface. Four species are recognized for Korean Elsholtzia by the identification key and descriptions in this study.

• Korean Journal of Plant Taxonomy
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• v.41 no.3
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• pp.259-266
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• 2011

Elsholtzia hallasanensis, E. springia, and E. splendens var. fasciflora (Lamiaceae) were reported recently as new species or new varieties of E. splendens according to their morphological characteristics. To reappraise the taxonomic status of these additional taxa and to determine the relationships between all Korean Elsholtzia taxa except E. saxatilis, which is distributed in North Korea, molecular studies based on the nrDNA (ITS) and cpDNA (rpl16, and trnH-psbA) sequences of seven taxa of Elsholtzia and one outgroup were carried out. The molecular data support that E. angustifolia and E. minima are distinct species from E. splendens and E. ciliata, respectively, because they have several private marker genes and show monophyly. The molecular data also support that E. splendens has a very close taxonomic relationship with both E. hallasanensis and E. springia. We found that E. splendens var. fasciflora, with multiple inflorescence, was based on several private marker genes and on the monophyly of its trees, suggesting that it can be considered as a variety. Elsholtzia springia, with the same sequences and the same morphological characteristics with E. hallasanensis after transplanting, should be treated as a synonym of E. hallasanensis. Moreover, we consider the taxonomic status of E. hallasanensis as E. splendens var. hallasanensis (Y. Lee) N.S. Lee & C.S. Lee, stat. nov.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.32 no.4 s.59
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• pp.219-225
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• 2006

In this study, we evaluated anti-oxidation, whitening and anti-inflammatory effects of Elsholtzia ciliata extract for use as the cosmeceuticals. Elsholtzia ciliata extracts (30, 70 and 100% methanol extract) exhibited a significant tree radical scavenging effect (up to 80% over 0.025% concentration of 30 and 70% methanol extract, over 0.01% concentration of 100% methanol extract) against DPPH radical generation and showed a significant inhibitory effect (up to 80% over 0.1% concentration) on melanin synthesis in B-16 Melanoma cells. We separated 4 fractions from Elsholtzia ciliata extract (70% methanol extract) by MPLC. The 1st, 2nd, and 3rd fractions showed anti-oxidation (DPPH radical scavenging activity and suppressive effect on Mn-SOD), whitening(inhibitory effect on melanin synthesis) and anti-inflammatory (suppressive effects on $IL-1{\alpha}$, IL-6, COX-2, and total NO synthesis) effects.

• Food Science and Biotechnology
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• v.17 no.2
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• pp.413-416
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• 2008

Effects of extracts obtained from the flowers of Elsholtzia splendens on the serum lipid profile and hepatotoxicity in mice were investigated. Female ICR mice were given E. splendens ethanolic extract (ESEs) orally at a dose of 10 or 50 mg/kg BW for 50 days. Significant dose-dependent decreases in triglyceride and low-density lipoprotein (LDL)-cholesterol of serum were observed. In addition, ESEs prolonged the lag-time of LDL oxidation in vitro. In the serum of ICE mice given ESEs orally at 10 and 50 mg/kg BW, the serum levels of aspartate aminotransferase (AST) and lactic dehydrogenase (LDH) increased significantly, while total protein, albumin, creatinine, alanine aminotransferase (ALT), and total bilirubin did not change. Therefore, ESEs may be beneficial to human health, although it has some hepatotoxicity.

• Food Science and Biotechnology
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• v.17 no.5
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• pp.1128-1130
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• 2008

The antioxidative properties of an Elsholtzia splendens ethanol extract (ESE) were examined in vivo. Oral administration of 10 or 50 mg ESE/kg BW in mice for 50 days resulted in a dose-dependent decrease in several biomarkers of oxidative stress including thiobarbituric acid reactive substance (TBARS), protein carbonyls, and serum 8-hydroxy-2'-deoxy guanosine (8-OH-dG). Moreover, the level of activity and mRNA expression of catalase and superoxide dismutase (SOD) were significantly increased by ESE treatment. Taken together, these results indicate that ESE may be beneficial to human health via its antioxidative properties.

• Korean Journal of Plant Resources
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• v.28 no.2
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• pp.243-252
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• 2015

This study was performed to establish a production system for in situ and ex situ conservation of Elsholtzia minima Nakai, an endemic plant grown in Jeju Island. Moreover, this study aimed to identify root-growth characteristics according to the use of pre-treatment agents and seedling growth effect according to fertilizer application. The mean temperature was similar in greenhouse and vinyl-moist chamber, but air humidity was higher in vinyl-moist chamber than in greenhouse. After stem planting of Elsholtzia minima Nakai, initial root growth was observed after 10 days in greenhouse and after 7 days in vinyl-moist chamber. Root growth rate was more rapid in vinyl-moist chamber. Moreover, survival rate, root growth rate and root number was slightly higher in vinyl-moist chamber than in greenhouse, indicating that vinyl-moist chamber is more effective in plant growth. When pre-treatment agents were used to remove root growth-inhibiting substances, a higher root growth rate of more than 95% was found in pre-treatment groups, excluding the group treated with AgNO₃ at 77.5%. Thus, Elsholtzia minima Nakai is thought to have less root growth inhibitors. In the analysis of nitrogen application rate and Osmocote application by seedling container, a difference was found in survival rate and growth according to application rate and container conditions. When Osmocote, a slow release fertilizer, was applied to the soil surface around each culture container, survival rate and the growth of aerial and root parts were most favorable. Thus, Osmocote fertilizer is thought to be desirable for seedling propagation of Elsholtzia minima Nakai.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.993-1000
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• 2023

Recently, enviromentally friendly natural substances derived from plants have been attracting attention as cosmetic materials, and research on various physiological activities of natural substances is being actively conducted. This study investigated the antioxidant, anti-inflammatory, moisturizing, and antibacterial effects of three types of extracts of mixtures containing different mixing ratios, Polygala tenuifolia, Angelica dahurica, and Elsholtzia splendens, known to have various physiological activities. The mixing ratio is 7 conditions (M1, 1:1:1; M2, 0.5:1.5:1; M3, 1.5:0.5:1; M4, 0.1:0.95:0.95; M5, 0.5:0.5:2; M6, 0.95 :1.95:0.1; M7, 1.45:0.1:1.45), and the optimal mixing ratio was confirmed for use as a cosmetic material. DPPH and ABTS radical scavenging activities showed scavenging abilities of 75.37% and 99.19%, respectively, at 1,000 ㎍/mL of M6. At a concentration of 200 ㎍/mL of M6, it showed 50% of nitric oxide production inhibition compared to the lipopolysaccharide-treated that induced an inflammatory response. It was confirmed that M3 and M6 produced hyaluronic acid 1.47 and 1.49 times higher than the control at a concentration of 50 ㎍/mL, respectively. Through the disc diffiusion test, the clear zone was 9.75 mm at 8 ㎍/mL of M6, confirming the inhibition of growth of staplylococcus aureus strain. Based on the above results, it is believed that the mixed extract of Polygala tenuifolia, Angelica dahurica, and Elsholtzia splendens can be used as a functional natural material for cosmetics.

• Journal of Applied Biological Chemistry
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• v.51 no.2
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• pp.69-72
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• 2008

• Bulletin of the Korean Chemical Society
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• v.28 no.3
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• pp.467-470
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• 2007