• 대한수의학회지
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• 제15권2호
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• pp.241-250
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• 1975

The light and electron microscopic observations were carried out in order to know the morphological changes of the testicular Leydig cells in the mouse injected with testosterone propionate for a long period. The results obtained were as follows: With the light microscopic study, atrophy of the Leydig cells and larger sudanophilic lipid granules in the experimental group than normal were observed. 2. By the electron microscopic finding, the small spherical or oval mitochondria, large lipid droplets, a decrease in number of smooth endoplasmic reticutum and distended saccular or vacuolar smooth endoplasmic reticulum were observed in the experimental group. Membranous whorls with droplet increased in number and size in the experimental group.

• Journal of the Korean Wood Science and Technology
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• 제33권5호통권133호
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• pp.7-12
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• 2005

The objective of this study is to estimate the mechanical behavior in bending and the anatomical changes of wood under several deflection rates. Sample specimens of water-saturated Japanese cedar (Cryptomeria japonica) were stressed to rupture under several deflection rates. Mechanical properties of wood such as modulus of elasticity, modulus of rupture and stress at proportional limit, and anatomical changes affected by deflection rates were estimated. Microscopic observations on compression side of the test specimens when the specimen was loaded to rupture were carried out by the SEM (scanning electron microscopy). The results are summarized as follows: 1. The mechanical properties of wood were affected by variations of the deflection rates. The modulus of elasticity (MOE), modulus of rupture (MOR) and stress at proportional limit were in proportion to the logarithm of deflection rates. 2. The deflection of wood at rupture in bending increased as deflection rates decreased. 3. The variations of the microscopic deformations of sample specimens were closely related to the deflection of wood at rupture. In case of largely deflected wood by maximum bending load, severe and abundant microscopic deformations were observed.

• Applied Microscopy
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• 제19권2호
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• pp.138-144
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• 1989

The specimens for electron microscopic observation made in different seasons have different qualities even though they are made by the same procedure. We observed the various specimens made in each four season. As the results, we concluded that the different specimen conditions were caused by the humidity and penetrability of various solution into the block. In spring, fall and winter, the quality of specimen is good and the difference with one another is not found. But in summer, the specimen have worse quality than in other seasons and not good for sectioning process and observation. In summer with high humidity, we can gain better specimens by eliminating the humidity as much as possible in all processes, thus increasing penetration of various solutions into the specimen.

• Childhood Kidney Diseases
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• 제15권1호
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• pp.29-37
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• 2011

신장질환은 같은 병명의 환자 일지라도 개개인의 증상과 치료에 대한 반응 정도가 다를 수 있기 때문에 신장병을 전공하는 임상의사는 신장병리에 대한 폭 넓은 지식이 치료에 많은 도움을 줄 수 있다. 이 논문에서는 생검 현장에서의 조직을 나누는 방법부터 기본적인 조직처리 과정까지를 설명함으로써 병리의 이해를 넓히고자 하였다. 광학현미경 판독을 위해서는 기본적인 특수 염색의 색깔 감별, 정상 사구체와 비정상 사구체의 감별점 등을 설명하였다. 면역형광 현미경 소견의 이해를 돕기 위하여 전형적인 막성사구체신병증과 IgA 신증의 침착 형태를 대표적으로 설명하였다. 전자현미경 판독을 위해서 면역 복합체인 고전자 밀도의 침착이 잘 생기는 부위를 질환별로 설명하여 참고가 되도록 하였고 전자현미경으로만 감별 가능한 질환들을 설명하였다. 이 논문은 신장질환의 병리학적 이해를 돕기 위한 소개에 불과하므로, 개별 질환의 판독을 위해서는 다른 신장병리 교과서나 문헌을 참고하여야 한다.

• Journal of Periodontal and Implant Science
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• 제37권2호
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• pp.251-263
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• 2007

The present study was performed to evaluate the effects of Tetracycline-HCI on the microstructure change of SLA implant surface according to application time. In the Tetracycline-HCI group, 6 implants were rubbed with sponges soaked $50mg/m{\ell}$ Tetracycline-HCI solution for O.5min., lmin., 1. 5min., 2min., 2.5min. and 3min. In the saline group. another 6 implants conditioned with sponges soaked saline using same methods. One implant wasn't conditioned anything. Then, the changes of surface roughness values were evaluated by optical interferometer & specimens were processed for scanning electron microscopic observation. The results of this study were as follows: 1. In both Tetracycline-HCI group & saline group, there are no significant differences between surface roughness values before & after surface detoxification. And in scanning electron microscopic observation. there are slightly changes of implant surface structures but this changes were not significant by comparison with no treatment implant surface. 2. In the changes of surface roughness values & the scanning electron microscopic observation, there were no significant differences between saline & Tetracycline-HCI groups. In conclusion, the detoxification with $50mg/m{\ell}$ Tetracycline-HCI within 3 minutes can be applied for treatment of peri-implantitis in SLA surface implants. without surface microstructure changes.

• 한국가축번식학회지
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• 제16권3호
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• pp.247-260
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• 1992

This study was carried out to investigate the histomorphological changes of ovaries obtained from 100 of 1-year-old female Korean loach(misgurnus anguillicaudatus). The light microscopic and ultrastructural changes ofooplasm and follicular membranes of oocytes, were observed by lightand transmission electron microscope during the reproductive cycle. All data were collected from November in 1991 to May in 1992. The results obtained in this study were as follows: The size of the nucleoli and number of the yolk granules increased as the oocytes grown. Yolk granules were loosely deposited in the oocytes as crystalline granules. Due to the presence of large early and late maturing oocytes, their ovaries were enlarged, transparent, granular and yellowish in color. The lattice was broken down at hydration, leaving the egg transparent. As the percentages of fish in LMO and RO stage increased from March to April, mean gonadosomatic index(GSI) values(18.49%) increased. Zona radiata change a squamous into cuboid shape in EMO stage. Processes from the granulosa cells and from the oocyte, microvilli grow and make contact with other in the pore canals of the zona radiata during vitellogenesis, but are withdrawn as the zona radiata becomes more compact and devoid of pore canals during oocyte maturation. Seasonal changes in the microscopic appearance of the ovaries were well correlated with those in both GSI and macroscopic appearance.

• 대한의생명과학회지
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• 제6권2호
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• pp.109-118
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• 2000

본 연구는 전자현미경적인 방법을 이용하여 흰쥐 기관지와 폐조직에 미치는 간접흡연의 영향을 조사하였다. 실험동물은 1일 3회씩 매회 15분간, 4주 동안 비주류 담배연기를 흡입하도록 하였다. 간접흡연 그룹의 폐조직에서는 세포질내에 다수의 용해소체을 함유하고 있는 중성구, 그리고 다양한 크기의 용해소체와 잔사체를 함유하는 대식 세포가 관찰되었다. 또한 폐포격벽은 팽대되었으며 섬유화현상이 나타났다. 기관지상피는 섬모상피세포가 점차 소실되었고, 분비세포 또는 배상세포들은 그 수가 증가하였으며, 섬모가 소실되고 표면적이 확장된 배상세포도 관찰되었다. 본 연구결과 이러한 미세구조의 변화는 간접흡연에 의한 세포상해의 전형적인 결과로 파악된다.

• Applied Microscopy
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• 제9권1호
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• pp.21-34
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• 1979

The cyclic changes of the epithelium of seminiferous tubule in the Korean greater horseshoe bat (Rhinolophus ferrumequinum korai) were investigated by means of the light and electron microscopic observations and the following results were obtained. 1) The spermatogenic function of the horseshoe bats captured in September was moderate but considerable amount of the ultrastructural findings were obtained in both the spermatocytogenic and the spermiogenic phases. 2) The spermatogenic function of the horseshoe bats captured in December was depressed representing a resting status. 3) The light and electron microscopic findings suggest that the epithelium of seminiferous tubule varies cyclically, which is closely related to their peculiar way of reproductive habit during hibernation.

• Journal of Periodontal and Implant Science
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• 제12권1호
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• pp.52.1-52.1
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• 1982

• Clinical and Experimental Reproductive Medicine
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• 제18권2호
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• pp.189-196
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• 1991

Long-term administration of luteinizing hormone-releasing hormone(LHRH) agonists, through a process of pituitary desensitization and down-regulation of receptors, inhibits the secretion of gonadotropin and sex-steroids and induces a reversible suppression of gonadal activity. This approach can be used as an effective endocrine therapy for some hormone-dependent tumors. We have used D-Trp6-LHRH, a long acting LHRH agonist, for the treatment of eleven patients with uterine leiomyomas, thereafter myomectomy was performed in seven cases and observed the ultrastructural changes of leiomyoma with an electron microscope. The use of LHRH agonist may be effective in reducing the size of a myoma considerably by primarily inducing medical hypophysectomy and would allow easier surgical removal. Electron microscopic findings of myoma cells after the use of LHRH agonist included the following: loss of cristae and swelling nuclear chromatin, perinuclear vacuolation in cytoplasm. Bone mineral density was slightly decreased, however, the difference was not statistically significant.