Electron Microscopic Studies on Testicular Leydig Cells of Mice Administered with Testosterone Propionate

Testosterone Propionate 투여로 인한 생쥐 고환(睾丸) Leydig Cell의 형태학적변화(形態學的變化)에 대한 전자현미경적연구(電子顯微鏡的硏究)

The light and electron microscopic observations were carried out in order to know the morphological changes of the testicular Leydig cells in the mouse injected with testosterone propionate for a long period. The results obtained were as follows: With the light microscopic study, atrophy of the Leydig cells and larger sudanophilic lipid granules in the experimental group than normal were observed. 2. By the electron microscopic finding, the small spherical or oval mitochondria, large lipid droplets, a decrease in number of smooth endoplasmic reticutum and distended saccular or vacuolar smooth endoplasmic reticulum were observed in the experimental group. Membranous whorls with droplet increased in number and size in the experimental group.