• 한국전기전자재료학회논문지
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• 제26권10호
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• pp.741-744
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• 2013

In this study, we fabricated anodic aluminum oxide (AAO) membrane by two step anodizing process for pH detection. The structural properties were observed by X-ray diffraction (XRD) and field emission scanning electron microscope (FE-SEM). Electrochemical measurements of the pH sensor have been performed in capacitance-voltage (C-V) and drift rates. The characterization of AAO membrane exhibited high sensitivity (99.1 mV/pH) at second anodizing time of 4 min.

• 센서학회지
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• 제19권2호
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• pp.67-86
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• 2010

Hydrogen is emerging as clean fuel and important industrial raw materials. The hydrogen gas is not sensed by the human olfactory system, But the combustion characteristics of hydrogen is that the ignition is very easy, the propagation speed of the flame is very fast and explosion limits is a wide range of 4 %~75 %. Therefore it is extremely in danger, and the need for its leakage detection technologies is especially important in places such as a production, transportation, storage and usage. The hydrogen sensors are classified with ceramic type, semiconductor type, optical type, electrochemical type and so on. Hydrogen sensors and their technologies are reviewed in detail for materials, fabrication process, sensing characteristics, good point and faults, and production and utilization of sensors be discussed.

• KSBB Journal
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• 제17권2호
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• pp.121-136
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• 2002

Immunosensors are of great interest because of their potential utility as specific, simple, label-free, direct detection means and provision of reduction in size, cost and time of analysis comparing with conventional immunoassay. In the last two decades, many reports have been published on the use of immunosensors for a wide range of applications to clinical diagnostics, pharmaceutical chemistry, environmental monitoring, biotechnology and food industries. There are also numerous transduction techniques developed such as electrochemical techniques, piezoelectric crystal, and surface plasmon resonance receiving much attention for the direct monitoring of immune reactions at solid surfaces. In this article, the principles, characteristics, structures, fonctions and clinical applications of immunosensors were reviewed

• 한국응용과학기술학회지
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• 제31권4호
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• pp.663-668
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• 2014

An in-vivo diagnosis of trace Mg(II) ion was performed using a low-cost and environment-friendly voltammetric method, using a graphite counter and reference electrodes and a fluorine-immobilized graphite working electrode, and clean deep seawater was used as an electrolyte solution. Under optimum conditions, the analytical working ranges attained microgram ranges, and a detection limit of $80.6ugL^{-1}$ was obtained using stripping voltammety with 60 sec accumulation time. Ex-vivo application was performed on fish liver and mice droppings. The developed techniques can be applicable to tumor cell analysis.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2006년도 영호남 합동 학술대회 및 춘계학술대회 논문집 센서 박막 기술교육
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• pp.65-70
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• 2006

In this study, a DNA chip with a microelectrode array was fabricated using microfabrication technology. Several probe DNAs consisting of mercaptohexyl moiety at their 5 end were immobilized on the gold electrodes by DNA arrayer. Then target DNAs were hybridized and reacted with Hoechst 33258, which is a DNA minor groove binder and electrochemically active dye. Linear sweep voltammetry or cyclic voltammetry showed a difference between target DNA and control DNA in the anodic peak current values. It was derived from Hoechst 33258 concentrated at the electrode surface through association with formed hybrid. It suggested that this DNA chip could recognize the sequence specific genes.

• Bulletin of the Korean Chemical Society
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• 제28권4호
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• pp.515-519
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• 2007

Neurotransmitter glycine in the nano gram range was analyzed using a paste electrode (PE) in cyclic voltammetry (CV) and square-wave stripping voltammetry (SWSV). An anodic peak caused by oxidation of the glycine ion appeared at the 0.4 V (versus Ag/AgCl/KCl) potential in a 0.1 M NH4H2PO4 electrolyte solution. At optimized conditions, the working range of the SWSV and CV concentration was found to be 5-60 ngL-1 glycine; precision of R2 = 0.9816 (SWSV) and 0.9986 (CV); and detection limit of 0.65 ngL-1 (5.82 × 10-12 molL-1) (S/N = 3). The optimized conditions were applied to an assay in a fish brain tissue and a living brain cell in real time.

• 통합자연과학논문집
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• 제3권4호
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• pp.237-240
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• 2010

Recently, number of studies for porous silicon have been investigated by many researchers. Multistructured porous silicon (PSi), distributed Bragg reflector (DBR) PSi, has been a topic of interest, because of its unique optical properties. DBR PSi were prepared by an electrochemical etch of $P^{{+}{+}}$-type silicon wafer of resistivity between 0.1 $m{\Omega}cm$ with square wave current density, resulting two different refractive indices. In this work, We have fabricated a simple and portable organic vapor-sensing device based on DBR porous silicon and investigated the optical characteristics of DBR porous silicon. DBR porous silicon have been characterized by FT-IR, Ocean optics 2000 spectrometer. The device used DBR PSi chip has been demonstrated as an excellent gas sensor, showing a great senstivity to a toxic vapor (TEP, DMMP, DEEP) at room temperature.

• Bulletin of the Korean Chemical Society
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• 제30권7호
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• pp.1593-1597
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• 2009

A biosensor has been developed based on induced wavelength shifts in the Fabry-Perot fringes in the visible reflection spectrum of appropriately derivatized thin films of porous silicon semiconductors. Porous silicon (PSi) was generated by an electrochemical etching of silicon wafer using two electrode configurations in aqueous ethanolic HF solution. Porous silicon displayed Fabry-Perot fringe patterns whose reflection maxima varied spatially across the porous silicon. The sensor system studied consisted of a mono layer of porous silicon modified with Protein A. The system was probed with various fragments of an aqueous Human Immunoglobin G (Ig G) analyte. The sensor operated by measurement of the Fabry-Perot fringes in the white light reflection spectrum from the porous silicon layer. Molecular binding was detected as a shift in wavelength of these fringes.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.1536-1537
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• 2007

본 논문은 당뇨병의 지표 물질인 glucose의 농도를 극미량의 시료를 사용하여 정량할 수 있는 방법을 개발하기 위해 organic/inorganic 네트웍에 의해 안정화된 나노입자 효소를 이용하여 초소형 효소 전극을 개발하였다. 전극은 실리콘 웨이퍼상에 반도체 공정을 이용하여 마이크로 크기의 금 박막 전극을 제작하였다, Organic/Inorganic 물질과 함께 합성된 glucose oxidase 나노입자는 20nm 크기로 투과형 전자현미경 (Transmission Electron Microscope:TEM)으로 관찰하고, 푸리에변환 적외선분광법(Fourier transform infrared spectrophotometer : FTIR) 을 이용하여 분석하였고, 전극 특성을 알아보기 위해 Potentiostat/Galvanostat을 사용하여 전기 화학 실험을 하였다. 제작된 전극은 시간대 전류법으로 glucose의 농도에 따른 감도를 측정하였다. 실험결과에 따라 전극의 표면에서 발생하는 전류는 glucose의 농도에 비례함을 알 수 있었다. 또한 순환 전압전류법을 통하여 감도를 측정하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.1375-1376
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• 2007

A synthesized 21-mer single-stranded DNA(ss DNA) was covalently immobilized onto a self-assembled aminoethanethiol monolayer modified gold electrode onto QCM. The covalently immobilized ssDNA was hybridized with complementary ssDNA. The interaction between surface immobilized ssDNA and complementary 21-mer DNA in solution was also examined. Each step was followed by monitoring changes in the QCM frequency with time. Also, PBS with pH 7.0 was selected as a supporting electrolyte in order to get maximum sensitivity and good bioactivity.