• Biomaterials Research
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• v.22 no.4
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• pp.235-248
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• 2018

Background: Injectable hydrogels have been extensively researched for the use as scaffolds or as carriers of therapeutic agents such as drugs, cells, proteins, and bioactive molecules in the treatment of diseases and cancers and the repair and regeneration of tissues. It is because they have the injectability with minimal invasiveness and usability for irregularly shaped sites, in addition to typical advantages of conventional hydrogels such as biocompatibility, permeability to oxygen and nutrient, properties similar to the characteristics of the native extracellular matrix, and porous structure allowing therapeutic agents to be loaded. Main body: In this article, recent studies of injectable hydrogel systems applicable for therapeutic agent delivery, disease/cancer therapy, and tissue engineering have reviewed in terms of the various factors physically and chemically contributing to sol-gel transition via which gels have been formed. The various factors are as follows: several different non-covalent interactions resulting in physical crosslinking (the electrostatic interactions (e.g., the ionic and hydrogen bonds), hydrophobic interactions, ${\pi}$-interactions, and van der Waals forces), in-situ chemical reactions inducing chemical crosslinking (the Diels Alder click reactions, Michael reactions, Schiff base reactions, or enzyme-or photo-mediated reactions), and external stimuli (temperatures, pHs, lights, electric/magnetic fields, ultrasounds, or biomolecular species (e.g., enzyme)). Finally, their applications with accompanying therapeutic agents and notable properties used were reviewed as well. Conclusion: Injectable hydrogels, of which network morphology and properties could be tuned, have shown to control the load and release of therapeutic agents, consequently producing significant therapeutic efficacy. Accordingly, they are believed to be successful and promising biomaterials as scaffolds and carriers of therapeutic agents for disease and cancer therapy and tissue engineering.

• Journal of Climate Change Research
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• v.4 no.3
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• pp.245-254
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• 2013

Korea government promote renewable energy as the core of their energy matrix to break the dependence and reduce greenhouse effects. This study analyzes the economic assessment of Solid Refuse Fuel project in urban area, considering the marginal external costs of air pollution in this area. Assessment index defined as costs (i.e., construction cost, operation cost) and benefit (margin, external cost) data which is located in Sudokwon landfill site. The result indicates that cost-benefit analysis of SRF is calculated as 1.0. In addition, SRF project is very sensitive about electric power selling price, operating cost and labor cost according to inflation rates. This study shows that the sustainability of SRF project is required the government financial support like investment funds as well as policy support. Variability analysis of SRF economic assessment due to renewable energy can be used for making policies in various fields such as waste and public energy field.

• Journal of the Korean Society of Marine Environment & Safety
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• v.12 no.2 s.25
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• pp.151-155
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• 2006

In these days, welding is the most commonly used metallic connection technology and also is the fundamental production technology of the modem industrial, which is used in various areas of the industrial fields, such as shipbuilding, automobiles, airplanes and plant facilities. However welding process produces strong light, electric currents, and fume gases etc., and the welding automation is not so easy compared to the other works of manufacturing industries which produce the standardized products in large quantities. So it is difficult to weld and detect the all kinds of seams automatically by a specific sensor. In this paper the sensor applying strain gauges is used to detect the seams of triangular wave form. With the auto carriage having the sensor we proposed the experiment to weld and track the seam automatically.

• Korean Journal of Soil Science and Fertilizer
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• v.44 no.3
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• pp.473-478
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• 2011

A wide diversity of liquid fertilizers and composts produced from the livestock manure in Korea is commonly applied to agricultural lands as an alternative of chemical fertilizers. However, their effects on the crop production and environmental impacts are still vague. The current study was conducted to understand the effects of the pig manure-based liquid fertilizer on the growth of Zea mays L. and soil properties. Four different liquid fertilizers were treated to each cultivated upland plot located in Gyeong-gi province, Korea while no fertilizer (control A) and a chemical fertilizer (control B) were treated to separate plots for comparison. The liquid fertilizer treatment did not make a significant difference in the fresh weight of Zea mays L. compared to the controls. This is probably due to the nutrient residues carried over from the last year fertilization. Electric conductivity (EC) and organic matter contents in soils were increased right after the liquid fertilizer treatments compared to the controls. However, soil pH was maintained as the same as the level of control A. A long-term effect of the continuous treatment of the manure based liquid fertilizer will be carried out in the successive study.

• Korean Journal of Plant Resources
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• v.31 no.6
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• pp.660-666
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• 2018

In order to understand the characteristics of soil according to the cultivation environment of Chinese bellflower (Platycodon grandiflorum A.), soil chemical properties of 12 collected soil samples from 6 cultivated fields in Okcheon, Chungbuk province in August. 2017 were analyzed. The soil pH was distributed within the range of 4.61 to 5.25 at all cultivation years and E.C (Electric Conductivity) and T-N (Total Nitrogen) of the cultivation year were not significant. Available $P_2O_5$ was higher than the average for medicinal crops and P. grandiflorum in Korea and C.E.C (Cation Exchange Capacity) was inconsistent for each cultivation year. In particularly, it was validated that the content of exchangeable cations K, Ca, Ma, and Na in this experiment was similar to that of C.E.C according to the cultivation years, because C.E.C had a high correlation with the exchangeable cations. For the available $P_2O_5$, as affected by trans-planting, 5Y-NT-H (cultivated 5 years and non-transplanted) had 58 mg/kg, while 5Y-T-H (cultivated 5 years and transplanted) had 246 mg/kg. The soil pH was found to be lower (acidic) in diseased soils than healthy soils. E.C was confirmed to be was higher in diseased soils than healthy soils except for the one cultivated for 2 years. The contents of T-N and available $P_2O_5$ were higher in diseased soil except for the one cultivated for 5 years and 11 years. The exchangeable cation K and Na tended to be higher in diseased soils rather than that in healthy soils, and the exchangeable cation Ca and Mg contents were higher in healthy soils than in diseased soils. The C.E.C of the soil was lower than that of healthy soils in all of the years except for the one which was cultivated for 5 years (transplanted).

• Journal of IKEEE
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• v.22 no.4
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• pp.1073-1078
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• 2018

As interest in the 4th Industrial Revolution increases, the CPS, in which things existing in the reality and things existing in the virtual interact with each other, is attracting attention as an important technology. Complex systems such as electric vehicles, autonomous driving, smart factories, and smart grid system are considered as core technology fields of the 4th Industrial Revolution, and many types of research have been conducted to develop it. The reliability of the system is directly related to the safety of people in case of the autonomous driving, and verification of the actual vehicle's hardware and software of ADAS is essential. In this paper, we proposed distributed simulation middleware supporting HILS for reliable verification of the complex hybrid systems.

• Geophysics and Geophysical Exploration
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• v.21 no.4
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• pp.231-243
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• 2018

Streaming potential (SP) arises from fluid flow through effectively connected pores. From this potential, formation water information as well as fluid flow properties can be estimated. As micro particles being located in boundary between subsurface porous media and fluid are charged to form electrical double layer, fluid flow caused by several reasons generates SP, one of electrokinetic phenomena. Occurrence mechanism of SP is complex and signal strength is relatively weak compared to noise. However, application of self potential survey using SP to monitoring of formation fluid is expanding because of its' convenience of exploration without artificial source and repetitiveness of signal. This paper accounts for the occurrence mechanism of SP studied before, including governing equations and analyzes previous various case studies of SP according to the change of physical properties of materials. It helps to increase understanding about SP and also lays the foundations of the application of SP to fields.

• Journal of Advanced Navigation Technology
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• v.23 no.5
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• pp.430-436
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• 2019

It is needed to develop an antenna with features of subminiature, light weight and multi-band operation for the variaty services in maritime and industrial fields. The PCB pattern antenna is one of the appropreiate antennas solving these requirements. In this research, the design and fabrication of the PCB pattern antenna operating on the single band of 920 MHz are investigated. The final goal is that the development of the dual band PCB pattern antenna operating on 260 MHz and 920 MHz, which is based on the proposed antenna. It is evident that the performance in the frequencies of 902 MHz, 915 MHz and 928 MHz among of 920 MHz ISM band is better than that in other frequencies. It is also confirmed that the differences of the voltage standing wave ratio, return loss, gain and efficiency between three frequencies are less than 5%. It is expected that the development of communication link of 5-10 km is possible when the induced results are applied into the low power wide area (LPWA) network desinged by the rule of -30 dB sensitivity.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.34 no.4
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• pp.191-197
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• 2021

To calculate the induced charge of atoms in molecular dynamics, linear equations for the induced charges need to be solved. As induced charges are determined at each time step, the process involves considerable computational costs. Hence, an efficient method for calculating the induced charge distribution is required when analyzing large systems. This paper introduces the Uzawa method for solving saddle point problems, which occur in linear systems, for the solution of the Lagrange equation with constraints. We apply the accelerated Uzawa algorithm, which reduces computational costs noticeably using the Schur complement and preconditioned conjugate gradient methods, in order to overcome the drawback of the Uzawa parameter, which affects the convergence speed, and increase the efficiency of the matrix operation. Numerical models of molecular dynamics in which two gold nanoparticles are placed under external electric fields reveal that the proposed method provides improved results in terms of both convergence and efficiency. The computational cost was reduced by approximately 1/10 compared to that for the Gaussian elimination method, and fast convergence of the conjugate gradient, as compared to the basic Uzawa method, was verified.

• Journal of the Korean institute of surface engineering
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• v.55 no.2
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• pp.102-119
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• 2022

Gold plating is used as a coating of connecter in printed circuit boards, ceramic integrated circuit packages, semiconductor devices and so on, because the film has excellent electric conductivity, solderability and chemical properties such as durability to acid and other chemicals. As increasing the demand for miniaturization of printed circuit boards and downsizing of electronic devices, several types of electroless gold plating solutions have been developed. Most of these conventional gold plating solutions contain cyanide compounds as a complexing agent. The gold film obtained from such baths usually satisfies the requirements for electronic parts mentioned above. However, cyanide bath is highly toxic and it always has some possibility to cause serious problems in working environment or other administrative aspects. The object of this investigation was to develop a cyanide-free electroless gold plating process that assures the high stability of the solution and gives the excellent solderability of the deposited film. The investigation reported herein is intended to establish plating bath composition and plating conditions for electroless gold plating, with thiomalic acid as a complexing agent. At the same time, we have investigated the solution stability against nickel ion and pull strength of solder ball. Furthermore, by examining the characteristics of the plated Au plating film, the problems of the newly developed electroless Au plating solution were improved and the applicability to various industrial fields was examined. New type electroless gold-plating bath which containing thiomalic acid as a complexing agent showing so good solution stability and film properties as cyanide bath. And this bath shows the excellent stability even if the dissolved nickel ion was added from under coated nickel film, which can be used at the neutral pH range.