• Title/Summary/Keyword: Elderly with Dementia

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Isolation of specific butyrylcholinesterase (BuChE) inhibitors from the rhizome extract of Curcuma zedoaria

  • Kim, Young-Sup;Park, Eun-Kyung;Heor, Jung-Hee;Kim, Seong-Kie;Kim, Jung-Sook;Choi, Yeon-Hee;Seo, Jee-Hee;Lee, Bong-Ho;Choi, Byoung-Wook
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.259.3-260
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    • 2003
  • Alzheimer's disease(AD) is the most common cause of senile dementia in elderly people and the causes of AD are currently not fully understood. However, AD is generally understood to be associated with reduced levels of acetylcholine in the brain as cholinergic neurons are lost and cholinergic neurotransmission declines. There are growing evidences that two types of cholinesterase(ChE), i.e., acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) both play important roles in the regulation of acetylcholine level in brain and thus may have a crucial role in the development and progression of AD. (omitted)

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Extracting of Interest Issues Related to Patient Medical Services for Small and Medium Hospital by SNS Big Data Text Mining and Social Networking (중소병원 환자의료서비스에 관한 관심 이슈 도출을 위한 SNS 빅 데이터 텍스트 마이닝과 사회적 연결망 적용)

  • Hwang, Sang Won
    • Korea Journal of Hospital Management
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    • v.23 no.4
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    • pp.26-39
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    • 2018
  • Purposes: The purpose of this study is to analyze the issue of interest in patient medical service of small and medium hospitals using big data. Methods: The method of this study was implemented by data mining and social network using SNS big data. The analysis tool were extracted key keywords and analyzed correlation by using Textom, Ucinet6 and NetDraw program. Findings: In the results of frequency, the network-centered and closeness centrality analysis, It was shown that the government center is interested in the major explanations and evaluations of the technology, information, security, safety, cost and problems of small and medium hospitals, coping with infections, and actual involvement in bank settlement. And, were extracted care for disabilities such as pediatrics, dentistry, obstetrics and gynecology, dementia, nursing, the elderly, and rehabilitation. Practical Implications: Future studies will be more useful if analyzed the needs of customers for medical services in the metropolitan area and provinces may be different in the small and medium hospitals to be studied, further classification studies.

Theory of Mind in Old Age: A Review from a Neurocognitive Perspective (노년기의 마음이론: 신경인지적 접근)

  • Park, Min
    • 한국노년학
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    • v.30 no.3
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    • pp.743-757
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    • 2010
  • Theory of mind (ToM) is the ability to infer one's own and other people's mental states such as beliefs, desires, and intentions. Although the majority of research in ToM has focused on young children or autistic individuals, several studies have investigated ToM in normal old age and in the demented elderly. This article provides an overview on existent findings of theory of mind in aging populations and suggests future directions for research including applying neuroimaging techniques and real-life tasks. It is still unclear how ToM in aging is associated with other aspects of cognition. However, it is expected that ToM perspective on aging will increase our understanding of aging of cognition and social functioning.

Associations of Cognitive Function and Dietary Factors in Elderly Patients with Alzheimer's Disease (알쯔하이머병 노인들의 인지기능과 관련된 식이 요인)

  • Jung, Kyong-Ah;Lee, Yo-A;Kim, Seong-Yoon;Jang, Nam-Soo
    • Journal of Nutrition and Health
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    • v.41 no.8
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    • pp.718-732
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    • 2008
  • The purpose of this study was to investigate nutrients or food factors related to cognitive function of elderly having Alzheimer's disease. In this study 38 subjects who were over 65 years old have participated in dementia clinic at A medical center. After they were diagnosed to Alzheimer's Disease (AD) through blood analysis, neuropsychological test, brain image and interview by medical specialist, we examined for their general information, anthropometry, blood pressure and dietary intakes. Dietary intakes were investigated using the 24-hour recall record. Energy intake was adequate and the energy composition of carbohydrate, protein and fat was 60.8 : 16.2 : 23.0, but dietary intakes of calcium, vitamin A and folate were less than 75% of the recommended intake levels for Koreans. The multiple regression analysis adjusted with age, sex and educational level showed that cognitive function was positively related to intakes of zinc, fishes and shellfishes, beans & nuts, sugars and fats, and negatively related to intakes of plant calcium and eggs. These results indicate that intakes of specific nutrients or food groups are associated with the specific domains of cognitive function in elderly with AD.

The Study on the Validity of the OHIP 14 (Oral Health Impact Profile 14) Using Health Index on Elderly Population, Gangneung City (강릉시 노인의 임상지표를 이용한 OHIP 14 (Oral Health Impact Profile 14)의 타당도 연구)

  • Lee, Ji-Youn
    • Journal of dental hygiene science
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    • v.9 no.4
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    • pp.475-483
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    • 2009
  • Subjects of the research were 668 elderly people aged over 65 from Gangneung city. OHIP 14 went through a first translation from English to Korean, discussion among experts, a second translation from Korean to English, and then the translation was approved. After the primary and main research were carried out, validity and correlation coefficient with the outcome of oral and mental health examination were studied. OHIP 14 in terms of the perception of oral health was relevant to the perception of overall health and oral health, the necessity of dental treatment, the satisfaction about oral health, the level of pain from observation, and the satisfaction about artificial tooth. OHIP 14 on account of oral health state was related to the number of present natural teeth, the necessity of dental treatment, and the status of no teeth. OHIP 14 according to overall health was correlated to the number of ailments, the state of mind, nerve systems, bones and sinews, digestive systems, urogenital systems, cerebrovascular systems, respiratory systems, eyes, ears, and dementia. OHIP 14 according to the perception of oral health showed a significant difference in the perception of overall health and oral health, the level of pain in terms of observation, and the satisfaction on artificial tooth. OHIP 14 on account of oral health state demonstrated a meaningful difference in the number of present natural teeth, the necessity of dental treatment, and status of no teeth. OHIP 14 in terms of overall health exhibited considerable difference in the state of mind, nerve systems, bones and sinews, digestive systems, cerebrovascular systems, respiratory systems, ears, and dementia. From the study, it was proven that there was relevance between the validity of OHIP 14 and the perception of oral health, the state of oral health, and the state of overall health in the experiment on some Korean elderly people.

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Predicting Healthy Lifestyle Patterns in Older Community Dwelling Adults: A Latent Profile Analysis (잠재프로파일 분석을 활용한 한국 노인 라이프스타일 유형화와 영향요인 분석)

  • Park, Kang-Hyun;Yang, Min Ah;Won, Kyung-A;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
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    • v.10 no.2
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    • pp.75-93
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    • 2021
  • Objective : The aim of this study was to identify subgroups of older adults with respect to their lifestyle patterns and examine the characteristics of each subgroup in order to provide a basic evidence for improving the health and quality of life. Methods : This cross-sectional study was conducted in South Korea. Community-dwelling older adults (n=184) above the age of 65 years were surveyed from April 2019 to May 2019. This study used latent profile analysis to examine the subgroups. Chi-squared (χ2) and multinomial logistic regression measures were then used to analyze individual characteristics and influencing factors. Results : The pattern of physical activity which is one of the lifestyle domains in elderly was categorized into three types: 'passive exercise type (31.1%)', 'low intensity exercise type (54.5%)', and 'balanced exercise type(14.5%)'. Activity participation was divided into three patterns: 'inactive type (12%)', 'self-management type (61%)', and 'balanced activity participation type (27%)'. In terms of nutrition, there were only two groups: 'overall malnutrition type (13.5%)' and 'balanced nutrition type (86.5%)'. Furthermore, as a result of the multinomial logistic regression analysis to understand the effects of lifestyle types on the health and quality of life of the elderly, it was confirmed that the health and quality of life were higher in those following an active and balanced lifestyle. In addition, gender, education level and residential area were analyzed as predictive factors. Conclusion : The health and quality of life of the elderly can be improved when they have balanced lifestyle. Therefore, an empirical and policy intervention strategy should be developed and implemented to enhance the health and quality of life of the elderly.

Status of health and nutritional intake of the elderly in long-term care facilities: focus on Gwangju Metropolitan City (노인의료복지시설 입소 노인의 건강 상태 및 영양소 섭취 현황: 광주광역시를 중심으로)

  • Han, Gyusang;Yang, Eunju
    • Journal of Nutrition and Health
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    • v.53 no.1
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    • pp.27-38
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    • 2020
  • Purpose: This study assessed the food intake and nutritional status of the elderly in long-term care facilities in order to provide adequate food services and improve the nutritional status. Methods: The survey was carried out from August 2019 to October 2019 for the elderly in long-term care facilities located in Gwangju Metropolitan City. The survey was conducted to collect data from 199 elderly persons (34 males and 165 females) aged over 65 years old. The food intake was assessed using a 1-day 24-hour recall method. Results: More than 90% of the subjects were over 75 years old. Forty five percent of the subjects were active, 44.2% of the subjects perceived themselves as not being healthy. Dementia and Parkinson's disease were the most common diseases, followed by hypertension, musculo-skeletal disease, diabetes, and stroke. Only 25.6% of the subjects had most of their teeth intact, and 44.7% of the subjects had difficulty in chewing and swallowing. The total food intake was 1,127 g in males and 1,078 g in females. The most frequently consumed foods were kimchi, cooked rice with multi-grains, soybean soup, cooked rice with white rice, yogurt, pumpkin porridge, soy milk, and duck soup. The average energy intake of the subjects was 1,564.9 kcal in males and 1,535.5 kcal in females. The overall nutritional status of the elderly in the long-term care facilities was poor. In particular, the intake of vitamin D and calcium, vitamin C, riboflavin, and potassium were very low. The intake of vitamin D was 5 ㎍, and 86.4% of the elderly were below the estimated average requirement, while the intake of sodium was high. Conclusion: The results of this study can be used to understand the health and nutritional status and to improve the food services and nutrition management for the elderly in longterm care facilities.

Comparison of Factors Associated With Agitation Among Youngest-Old, Middle-Old, and Oldest-Old Hospitalized Patients Referred to the Psychiatric Department (정신건강의학과에 협진의뢰된 연소노인, 고령노인, 초고령노인 입원환자의 초조의 연관요인 비교)

  • Min-Suk Jang;Seo-Hyun Choi;Se-ri Maeng;Yang-Sik Kim;Jae-Nam Bae;Jeong-Seop Lee;Won-Hyoung Kim
    • Korean Journal of Psychosomatic Medicine
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    • v.31 no.2
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    • pp.89-99
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    • 2023
  • Objectives : In this study, elderly hospitalized patients aged 65 years or older who were admitted to a university hospital and referred to the department of psychiatry were classified into youngest-old, middle-old, and oldest-old. It was conducted to find out what factors contribute to the agitation pattern by age group, whether there is a difference in the factors, and whether there is a difference in the severity of the agitation pattern. Methods : From July 1, 2021 to December 31, 2021, the medical records of patients aged 65 years or older who were referred to the department of psychiatry were retrospectively reviewed. Age, gender, route of hospitalization, department of referral, reason for referral, treatment method, presence of internal and surgical diseases, and hematological test data were investigated. Results : There was a significant correlation with the RASS score in cases of surgery referral and high CRP levels for youngest-old aged 65 to 74 years, in cases of surgery referral, dementia and hyponatremia for middle-old aged 75 to 84 years, in case of dementia for oldest-old aged 85 years old or older. In addition, there were differences in the severity of agitation patterns between age groups. Conclusions : As the age group increases, the agitation of delirium patients becomes more severe, and various factors contributing to the agitation pattern also differ by age group. Therefore, when treating elderly patients with delirium, attention should be paid to factors that may affect agitation depending on age.

The Impact of Family Caregiving for the Elderly with Dementia on Depression in the United States: Does the Relationship of Caregivers to Care Recipients Matter? (미국 치매노인 부양자의 우울증에 영향을 미치는 요소: 배우자 부양자와 딸 부양자 비교 연구)

  • Baek, Ju-Hee;Zarit, Steven H.
    • 한국노년학
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    • v.29 no.4
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    • pp.1591-1609
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    • 2009
  • Adult child caregivers and spousal caregivers might deal with differential challenges. Studies about caregivers' psychological outcomes, however, tended to investigate associations between caregiving and its outcomes by pooling adult child caregivers and spousal caregivers together. By using a U. S. sample of family caregivers who assisted a relative with dementia, this study examined whether the relationship of caregivers to care receivers (daughter caregivers or spousal caregivers) made a difference in levels of depressive symptoms. The result showed that wife caregivers were more likely to be depressed than daughter caregivers. For daughter caregivers, role overload, role captivity, and behavior problems significantly influenced on depression. Besides these variables, the level of education was a significant predictor for wife caregivers. Role captivity and behavior problems significantly impacted on depression for husband caregivers. Thus, role captivity and behavioral problems were common predictors for all the caregivers. Specifically, higher levels of role captivity and behavioral problems were likely to make caregivers more depressed. The implication of these results were discussed.

The Family Caregivers' Stress Pathways by Types of Long Term Care Services for the Elderly (장기요양보호서비스 유형별 가족 부양스트레스 경로)

  • Park, Chang-Je;Lee, Sung-Jin
    • 한국노년학
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    • v.31 no.3
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    • pp.831-848
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    • 2011
  • The purpose of this study is to analyse the family caregivers' stress pathways by types of long term care services for the elderly, and then to discuss the findings of analysis. For this research, primary caregivers that provide care the elderly requiring long term care services sanctioned by National Health Insurance Corporation were drawn and surveyed. Among collected data, data for 258 primary caregivers by type of long term care services were used for this study. The results of this study can be summarized as follows. First, on average, the elders that utilize care service in institutions for the elderly were higher proportion of women, older, higher rate of bereavement, more children than the elders that utilize in-home care service, but some cases were vice-versa. Second, the elders that utilize care service in institutions more ADL dependency, higher proportion of severe dementia or severe stroke, higher care rank by National Health Insurance Corporation than the elders that utilize in-home care service on average. Third, primary caregivers with elders that utilize in-home care service were higher proportion of women, older, lower education level, higher rate of spouse and daughter-in-law in relationship with care recipient, less health, lower income than primary caregivers with elders that utilize care service in institutions. Fourth, subjective indicators representing caregivers' reactions to caregiving for the elderly significantly impact on caregivers' stress(ie, depression), and pathway of caregivers' stress are differentiated by type of long term care services. Fifth, stressors that have direct impacts on depression as caregiving family are differentiated by type of long term care services. Therefore, policies or programs to reduce negative mental health or stress of caregivig families should be designed differently by reflecting pathway of various stressors and stress by use types of long term care services for the elderly.