• Journal of The Korean Astronomical Society
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• v.53 no.6
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• pp.161-168
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• 2020

We report the discovery of a giant exoplanet in the microlensing event OGLE-2017-BLG-1049, with a planet-host star mass ratio of q = 9.53 ± 0.39 × 10-3 and a caustic crossing feature in Korea Microlensing Telescope Network (KMTNet) observations. The caustic crossing feature yields an angular Einstein radius of θE = 0.52 ± 0.11 mas. However, the microlens parallax is not measured because the time scale of the event, tE ≃ 29 days, is too short. Thus, we perform a Bayesian analysis to estimate physical quantities of the lens system. We find that the lens system has a star with mass Mh = 0.55+0.36-0.29 M⊙ hosting a giant planet with Mp = 5.53+3.62-2.87 MJup, at a distance of DL = 5.67+1.11-1.52 kpc. The projected star-planet separation is a⊥ = 3.92+1.10-1.32 au. This means that the planet is located beyond the snow line of the host. The relative lens-source proper motion is μrel ~ 7 mas yr-1, thus the lens and source will be separated from each other within 10 years. After this, it will be possible to measure the flux of the host star with 30 meter class telescopes and to determine its mass.

• Journal of Microbiology and Biotechnology
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• v.32 no.6
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• pp.730-739
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• 2022

Methicillin-resistant Staphylococcus aureus (MRSA) causes severe infections and poses a global healthcare challenge. The utilization of novel molecules which confer synergistical effects to existing MRSA-directed antibiotics is one of the well-accepted strategies in lieu of de novo development of new antibiotics. Thymol is a key component of the essential oil of plants in the Thymus and Origanum genera. Despite the absence of antimicrobial potency, thymol is known to inhibit MRSA biofilm formation. However, the anti-MRSA activity of thymol analogs is not well characterized. Here, we assessed the antimicrobial activity of several thymol derivatives and found that 4-chloro-2-isopropyl-5-methylphenol (chlorothymol) has antimicrobial activity against MRSA and in addition it also prevents biofilm formation. Chlorothymol inhibited staphyloxanthin production, slowed MRSA motility, and altered bacterial cell density and size. This compound also showed a synergistic antimicrobial activity with oxacillin against highly resistant S. aureus clinical isolates and biofilms associated with these isolates. Our results demonstrate that chlorinated thymol derivatives should be considered as a new lead compound in anti-MRSA therapeutics.

• Proceedings of the Optical Society of Korea Conference
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• 2000.08a
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• pp.74-75
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• 2000

The past few decades have witnessed the development of very robust technique, known as magneto-optical trap(MOT), for cooling and trapping of neutral atoms using lasers and magnetic fields. This technique can easily produce cooled atoms to a temperature range of nano-kelvin $s^{(1)}$ . These laser cooled and trapped atoms have found applications in various fields, such as ultrahigh resolution spectroscopy, precision atomic clocks, very cold atomic collision physics, Bose-Einstein Condensation, the Atom laser, etc. Particularly, a few isolated atoms of very low temperature are needed in the cavity QED studies in the optical regime. One can obtain such atoms from a MOT using the atomic fountain technique. The widely used technique for atomic fountain is, first to cool and trap the neutral atoms in MOT. And then launch them in the vertical (1, 1, 1) direction with respect to cooling beams, using moving molasses technique. Recently, this technique combined with the cavity-QED has opened an active area of basic research. This way atoms can be strongly coupled to the optical radiation in the cavity and leads to various new effects. Trapping of single atom after separating it from MOT in the high Q-optical cavity is actively initiated presentl $y^{(2.3)}$. This will help to sharpen our understanding of atom-photon interaction at quantum level and may lead to the development of single-atom laser. Our efforts to develop an $^{85}$ Rb-atomic fountain is in progress. (omitted)

• Journal of Sensor Science and Technology
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• v.31 no.3
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• pp.175-179
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• 2022

The physical properties of biomaterials are important for their isolation and separation from body fluids. In particular, the precise evaluation of the multi-physical properties of single biomolecules is essential in that the correlation between physical and biological properties of specific biomolecule. However, the majority of scientific equipment, can only determine specific-physical properties of single nanoparticles, making the evaluation of the multi-physical properties difficult. The improvement of analytical techniques for the evaluation of multi-physical properties is therefore required in various research fields. In this study, we developed a motion-tracking algorithm to evaluate the multi-physical properties of single-nanoparticles by analyzing their behavior. We observed the Brownian motion and electric-field-induced drift of fluorescent nanoparticles injected in a microfluidic chip with two electrodes using confocal microscopy. The proposed algorithm is able to determine the size of the nanoparticles by i) removing the background noise from images, ii) tracking the motion of nanoparticles using the circular-Hough transform, iii) extracting the mean squared displacement (MSD) of the tracked nanoparticles, and iv) applying the MSD to the Stokes-Einstein equation. We compared the evaluated size of the nanoparticles with the size measured by SEM. We also determined the zeta-potential and surface-charge density of the nanoparticles using the extracted electrophoretic velocity and the Helmholtz-Smoluchowski equation. The proposed motion-tracking algorithm could be employed in various fields related to biomaterial analysis, such as exosome analysis.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.60.2-60.2
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• 2021

중력파 관측은 2015년에 사상 최초로 검출에 성공한 이래, 불과 5년 만에 주 1 회 이상 안정적으로 검출되고 있으며 검출기들의 성능이 계속 향상됨에 따라 관측 범위와 빈도가 급격히 확대되는 추세에 있다. 이제 중력파는 전자기파 외에 우주를 보는 새로운 창으로서 확고한 지위를 구축하고 있으며 향후 무궁무진한 발전의 잠재력을 보여주고 있다. 이러한 가능성을 일찌감치 내다본 미국과 유럽의 선도 국가들은 현재 운영 중인 LIGO와 Virgo 검출기의 지속적인 업그레이드는 물론 Cosmic Explorer, Einstein Telescope 등 차세대 거대 검출기 개발을 병행해서 진행하고 있으며, 일본, 인도, 중국, 호주 등 후발주자들도 제각기 다양한 중력파 검출기 계획들을 추진하고 있다. 이에 한국천문연구원에서도 2019년부터 중력파 검출기술 연구를 시작하였으며, 특히 한국과학기술원 물리학과와 협력하여 차세대 핵심기술인 양자잡음 저감기술을 중점적으로 개발하고 있다. 이 발표에서는 본 연구팀의 최근 연구 진행상황을 요약하고 국제 중력파 검출기 공동개발 참여 현황을 소개한다.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.85-85
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• 2020

South Korea experiences few large scale erosion and sedimentation problems, however, there are numerous local sedimentation problems. A reliable and consistent approach to modelling and management for sediment processes are desirable in the country. In this study, field measurements of sediment concentration from 34 alluvial river basins in South Korea were used with the Modified Einstein Procedure (MEP) to determine the total sediment load at the sampling locations. And then the Flow Duration-Sediment Rating Curve (FD-SRC) method was used to estimate the specific degradation for all gauging stations. The specific degradation of most rivers were found to be typically 50-300 tons/㎢·yr. A model tree data mining technique was applied to develop a model for the specific degradation based on various watershed characteristics of each watershed from GIS analysis. The meaningful parameters are: 1) elevation at the middle relative area of the hypsometric curve [m], 2) percentage of wetland and water [%], 3) percentage of urbanized area [%], and 4) Main stream length [km]. The Root Mean Square Error (RMSE) of existing models is in excess of 1,250 tons/㎢·yr and the RMSE of the proposed model with 6 additional validations decreased to 65 tons/㎢·yr. Erosion loss maps from the Revised Universal Soil Loss Equation (RUSLE), satellite images, and aerial photographs were used to delineate the geospatial features affecting erosion and sedimentation. The results of the geospatial analysis clearly shows that the high risk erosion area (hill slopes and construction sites at urbanized area) and sedimentation features (wetlands and agricultural reservoirs). The result of physiographical analysis also indicates that the watershed morphometric characteristic well explain the sediment transport. Sustainable management with the data mining methodologies and geospatial analysis could be helpful to solve various erosion and sedimentation problems under different conditions.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.427-427
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• 2022

하천에서 유사량 자료는 하천의 이·치수 목적으로 활용할 수 있는 기본 자료중 하나로서 하상 변동 예측, 저수지 퇴사량 추정, 하도 계획과 설계, 유사조절 계획 수립 및 기타 구조물 등의 영향 평가 등 다양하게 활용할 수 있다. 본 연구에서는 신뢰성 높은 유사량 자료를 생산하기 위하여 국가유사량관측망 중 27개 지점에 대하여 유사량의 측정 및 특성분석을 수행하였다. 유사량 측정과정은 사전조사, 현장측정, 실험실분석, 모형적용(총유사량 산정) 단계로 구분할 수 있다. 사전조사 단계에서는 현장관련 정보를 수집하여 현장측정 계획 및 현장 안전대책을 수립하고, 현장측정 단계에서는 사전조사 단계에서 수립한 계획을 바탕으로 유사량을 측정하였다. 유사량 측정시 측선은 ISO 기준 이상의 5~7개로 측선을 나누어 측정하였고, 측정장비는 D-74, DH-48 부유사 채취기를 이용하여 왕복수심적분법으로 수행하였다. 실험실분석은 한국수자원조사기술원 유사량 실험실에서 채취시료에 대한 농도, 레이저회절법을 이용한 입도분석, 하상토분석(체분석), 비중실험을 수행하였다. 총유사량 산정을 위한 모형적용 단계에서는 수정-아인슈타인법(Modified Einstein Method)을 적용하였다. 또한, 유량-부유사량 농도 변화양상과 부유사량 특성 분석을 이용한 부유사량 측정결과를 평가하였고 각 지점의 부유사량특성을 잘 나타낼 수 있는 지수식(Q_ss = aQ^b)을 이용하여 유량-부유사량관계곡선식을 개발하였다.

• Clinical Endoscopy
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• v.57 no.1
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• pp.105-111
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• 2024

Background/Aims: The pancreatic pseudocyst (PP) is a type of fluid collection that typically develops as a delayed complication of acute pancreatitis. Drainage is indicated for symptomatic patients and/or associated complications, such as infection and bleeding. Drainage modalities include percutaneous, endoscopic, laparoscopic, and open drainage. This study aimed to assess trends in the utilization of different drainage modalities for treating PP from 2016 to 2020. The trends in mortality, mean length of hospital stay, and mean hospitalization costs were also assessed. Methods: The National Inpatient Sample database was used to obtain data. The variables were generated using International Classification of Diseases-10 diagnostic and procedural codes. Results: Endoscopic drainage was the most commonly used drainage modality in 2018-2020, with an increasing trend over time (385 procedures in 2018 to 515 in 2020; p=0.003). This is associated with a decrease in the use of other drainage modalities. A decrease in the hospitalization cost for PP requiring drainage was also noted (29,318 United States dollar [USD] in 2016 to 18,087 USD in 2020, p<0.001). Conclusions: Endoscopic drainage is becoming the most commonly used modality for the treatment of PP in hospitals located in the US. This new trend is associated with decreasing hospitalization costs.

• Journal of the Microelectronics and Packaging Society
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• v.31 no.2
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• pp.54-62
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• 2024

SICM (Scanning Ion Conductivity Microscopy) is a technique for measuring surface topography in an environment where electrochemical reactions occur, by detecting changes in ion conductivity as a nanopipette tip approaches the sample. This study includes an investigation of the current response curve, known as the approach curve, according to the distance between the tip and the sample. First, a simulation analysis was conducted on the approach curves. Based on the simulation results, then, several measuring experiments were conducted concurrently to analyze the difference between the simulated and measured approach curves. The simulation analysis confirms that the current squeezing effect occurs as the distance between the tip and the sample approaches half the inner radius of the tip. However, through the calculations, the decrease in current density due to the simple reduction in ion channels was found to be much smaller compared to the current squeezing effect measured through actual experiments. This suggests that ion conductivity in nano-scale narrow channels does not simply follow the Nernst-Einstein relationship based on the diffusion coefficients, but also takes into account the fluidic hydrodynamic resistance at the interface created by the tip and the sample. It is expected that SICM can be combined with SECM (Scanning Electrochemical Microscopy) to overcome the limitations of SECM through consecutive measurement of the two techniques, thereby to strengthen the analysis of electrochemical surface reactivity. This could potentially provide groundbreaking help in understanding the local catalytic reactions in electroless plating and the behaviors of organic additives in electroplating for various kinds of patterns used in semiconductor damascene processes and packaging processes.

• The Journal of the Korea Contents Association
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• v.10 no.8
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• pp.147-158
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• 2010

The Soviet Silent Films in the 1920s, produced a brilliant prosperity in the history of world films in the cultural and artistic aspects. Among them, Dziga Vertov was a film theorists and a practitioner along with Sergei M. Einstein played a pivotal role in the contemporary soviet films at the time. But the film theories of Vetro is incorrectly recognized or specialized compared to the theories of Eisenstein. But Deleuze has stated that the short in the movie of Vertov is able to deliver a meaning and an impact and he has emphasized that a short can be significant by itself by focusing on the 'truth' which a documentary must have. His film theories are based on futurism and constructivism and use the 'kino-eye' method and 'Interval' theory to summarize and organize his movies into 'movie-truth' principal and 'life as itself' concept. Deleuze the purpose of this research is to analyze with the Vertov core of film theory and every theory of kino eye as the foundation and by comparing the Montage Theory of Sergei Eisenstein and applying Deleuze's Image Theory. Furthermore, it can be insufficient to discuss the film commercial achievements of Vertov as a result of inadequacy of previous research but it will further study his innovative methods and depth of his theories in his representation form in the documentary films.