• The Journal of Korean Academic Society of Nursing Education
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• v.18 no.2
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• pp.248-258
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• 2012

Purpose: The purpose of this study was to compare the effects of CEDA (Cross Examination Debate Association) debate with those of traditional lecture education on moral judgment and ethical values using the Korean version of DIT and the ethical values. Methods: The experiment was performed for 9 weeks, from September 2 to November 12, 2010. Participants were 71 undergraduate nursing students in a nursing college, assigned to an experimental group (36 students) or a control group (35 students). The design of this study was a non equivalent control group pretest-posttest design. Results: The experimental group reported significantly higher scores of the 4 stage scores of moral judgment (t=-2.19, p=.036) and ethical values (t=3.04, p=.004) than the control group. However, no significant differences were found in the P score of moral judgment between the two groups. Conclusion: The findings of this study showed the benefits of providing a CEDA debate course for nursing ethics education. Therefore, in further studies, it is necessary to develop various teaching strategies or educational programs to improve nursing ethical values and moral judgment.

• International Journal of Railway
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• v.2 no.2
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• pp.60-69
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• 2009

In recent years, technology developments in different countries, especially in newly industrialized countries, are extremely indebted to appropriate technology transfer by these countries. Nevertheless the technology transfer process in the present situation is complex, and its success is related to the coordination rate with the political, economic, social, and environmental objectives of countries. Today debates related to the transfer of the technical know how accompanied by equipment hardware has found remarkable importance such that countries seek increasing comprehensive capabilities in the field of transferred technology for which Preventive Maintenance (PM) is one of the aspects. This research with the purpose to determine the technological capability level and to study the role of PM in the effective & appropriate technology transfer in subway industry is carried out for presenting a suitable model for the technology transfer in this industry with an attitude towards the effects of principal PM factors. For this purpose, after the study of different and relevant models existing in the field of suitable methods for technology transfer, some equipment PM theories and models were selected as the base for the compilation of the questionnaire. With the help of questionnaire, main PM factors that are effective in the field of technology transfer were extracted, and finally, their effects on technology transfer were analyzed, identified and a comprehensive model suggested in this connection.

• Journal of Regulation Studies
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• v.27 no.1
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• pp.123-151
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• 2018

There have been voluminous debates on the economic effects of the Sunday shopping restriction in Korea. This paper summarizes the issues on the restriction, critically reviews the previous researches, and proposes policy alternatives. First, the Sunday shopping restriction in Korea significantly lowers supply-side efficiency. Second, the restriction considerably reduces demand-side efficiency due to higher transaction costs. Third, there is no empirical evidence showing the restriction improves equity overall. Fourth, even if equity improvement occurs, there are a number of policy alternatives that can achieve the same equity effect with less efficiency loss.

• Korean journal of communication and information
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• v.44
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• pp.108-143
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• 2008

Candidate images refer to a holistic impression of a candidate which is composed of various dimensions of attributes. This study investigated how online and offline news media, campaign media such as political ads, televised debates, and candidate web-sites, and interpersonal political talk influenced voters' images of a candidate in such dimensions as personal traits, job-performance abilities, and policy capabilities, and further their political decision making in the 17th presidential election in Korea. The analysis focused on President Lee, Myung Bak who won the election by obtaining nearly 50% of the effective votes. According to the data analyses, first, uses of offline newspapers positively influenced voters' images of candidate Lee's personal traits such as his morality, integrity, trustworthiness, and compassion, yet online news uses had an opposite effect on voters' impression of his job-performance and economic policy capabilities. Secondly, among various campaign media, television ads and candidate web-sites positively contributed to the formation of candidate Lee's images, yet showed little direct effect on vote choice, indicating that campaign media mainly indirectly influenced voters' political decision making. Each of the first, second, and third televised candidate debates revealed unique effects on image formation and vote choice. Thirdly, the network size and frequency of political talk negatively influenced image formation regarding candidate Lee's personal traits and economic policy capabilities, yet the discussion network size positively contributed to the Lee votes. Forth, among various dimensions of candidate images, voters' perceptions of candidate Lee's personal traits appeared to be the most significant predictor of the support for him.

• Annals of Clinical Neurophysiology
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• v.19 no.2
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• pp.93-100
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• 2017

In this article, we review the differences of the brain morphology according to age, sex, and handedness. Age is a well-known factor affecting brain morphology. With aging, progressive reduction of brain volume is driven. Sex also has great effects on brain morphology. Although there are some reports that the differences of brain morphology may originate from the differences of weight between the 2 sexes, studies have demonstrated that there are regional differences even after the correction for weight. Handedness has long been regarded as a behavioral marker of functional asymmetry. Although there have been debates about the effect of handedness on brain morphology, previous well-established studies suggest there are differences in some regions according to handedness. Even with the studies done so far, normal brain morphology is not fully understood. Therefore, studies specific for the each ethnic group and standardized methods are needed to establish a more reliable database of healthy subjects' brain morphology.

• Bulletin of the Korean Chemical Society
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• v.33 no.10
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• pp.3265-3268
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• 2012

Nanoparticles (NPs) are increasingly used in consumer products, which have aroused many concerns and debates regarding their fate in biological systems from a point of their safety/toxicity. Although a number of studies on the biological effects of NPs have been published, these are often complicated by the possible toxicity of conventional NPs, caused by contamination with chemical precursors or additives during their synthesis and/or purification procedures. To explicitly understand the toxicity basis of NPs, it is necessary to directly address a main problem related to their intrinsic/inherent toxicity and/or incompatibility with biological objects. The present study is designed to take advantage of a novel laser-assisted method called laser ablation to generate Ag, Au, Co, and Cu NPs in biocompatible aqueous solution, and to evaluate the toxicity of the resulting ultra-pure NPs. Our results show that the ultra-pure NPs with nascent surfaces possess moderate cytotoxicity to human cells in a cell-dependent manner.

• Atmosphere
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• v.9 no.1
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• pp.12-19
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• 1999

Ever though the authentic history on the first war between Kokurye and Sao-dynasty is not good enough. there are many kinds of suppositions and debates upon this war in the current history books. This study gathered current and old historical records and analyzed the next five results. First. Chang-rna (the rainy season of Korea) had a great effects on the battle. Second. unlike the authentic history. the war seized not only the effect of Chang-rna but also the battle action. Third, battle field is supposed have been in Im-yu-goan. Fourth, the Kokurye force did not come across the Chang-rna but made a great victory by using it intentionally. Fifth. there was a great strategist at that times whose name was Kang-Ie-Sik. But. in spite of many positive records there is little doubt on that he was the commander of the Im-yu-goan battle.

• Journal of Society of Preventive Korean Medicine
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• v.20 no.1
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• pp.145-159
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• 2016

Objectives : The aim was to investigate the characteristics of low dose effect and non monotonic dose responses(NMDRs) and to predict the influence it might have on the health and medicine, traditional Korean medicine. Methods : By investigating recently published major literatures related to low dose effect and NMDRs, the definition, mechanism, major related fields, and the influence on public health and medicine has been categorized and summarized. Results : Although there are still heated debates about the definition of low dose, it implies the biological responses in environmental exposure level and the NDMDRs means the nonlinear relationship between the dose-response in the slope sign change. Also, it implies the new form of the curve showing a U, reverse U shape, and the slop sign constantly changing showing various forms. This mechanism is because the two acceptor shows opposing effects to toxic materials and the affinity is different along with the numerical value that increase and decrease being different. These characteristics generally appear in endocrine disrupters such as bisphenol A, agricultural pesticides, metal, and radiation. The research field in the public health and medical treatment is obesity, problems in metabolism, growth hormone treatment, climacteric treatment, breast cancer, intake of Korean traditional medicine for pregnancy, menopause and phytoestrogen. Conclusions : As a result of discussing implications, NMDRs is a particular effect in low dose and heated debates surround this response, research is being conducted surrounding the field of obesity, problems in metabolism, growth hormone treatment, climacteric treatment, breast cancer, intake of Korean traditional medicine for pregnancy, menopause, and phytoestrogen. More research and interest in needed as it can have a massive influence in the public health and medicine.

• Journal of Soil and Groundwater Environment
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• v.17 no.1
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• pp.33-41
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• 2012

Nanoscale zero-valent iron (nZVI) has recently received much attention for remediation of soil and groundwater contaminated with trichloroethylene (TCE). But there have been many debates on the toxic or inhibitory effects of nZVI on the environment. The objective of this study was to investigate the effects of nZVI on the activity of Geobacter lovleyi and to determine the potent effect of combination of abiotic and biotic treatment of TCE dechlorination. TCE degradation efficiencies of Geobacter lovleyi along with nZVI were more increased than those when nZVI was solely used. The amount of total microbial protein was increased in the presence of nZVI and hydrogen evolved from nZVI was consumed as electron donor by Geobacter lovleyi. In addition, dechlorination of TCE to cis-DCE by Geobacter lovleyi along with nZVI in respiking of exogenous of TCE shows that the reactivity of Geobacter lovleyi was also maintained. These results suggest that the application of Geobacter lovleyi along with nZVI for the dehalorination is beneficial for the enhancement of TCE degradation rate and reactivity of Geobacter lovleyi.

• Genomics & Informatics
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• v.19 no.4
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• pp.39.1-39.8
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• 2021

Tamoxifen (TAM) is an anticancer drug used to treat estrogen receptor (ER)-positive breast cancer. However, its ER-independent cytotoxic and antifungal activities have prompted debates on its mechanism of action. To achieve a better understanding of the ER-independent antifungal action mechanisms of TAM, we systematically identified TAM-sensitive genes through microarray screening of the heterozygous gene deletion library in fission yeast (Schizosaccharomyces pombe). Secondary confirmation was followed by a spotting assay, finally yielding 13 TAM-sensitive genes under the drug-induced haploinsufficient condition. For these 13 TAM-sensitive genes, we conducted a comparative analysis of their Gene Ontology (GO) 'biological process' terms identified from other genome-wide screenings of the budding yeast deletion library and the MCF7 breast cancer cell line. Several TAM-sensitive genes overlapped between the yeast strains and MCF7 in GO terms including 'cell cycle' (cdc2, rik1, pas1, and leo1), 'signaling' (sck2, oga1, and cki3), and 'vesicle-mediated transport' (SPCC126.08c, vps54, sec72, and tvp15), suggesting their roles in the ER-independent cytotoxic effects of TAM. We recently reported that the cki3 gene with the 'signaling' GO term was related to the ER-independent antifungal action mechanisms of TAM in yeast. In this study, we report that haploinsufficiency of the essential vps54 gene, which encodes the GARP complex subunit, significantly aggravated TAM sensitivity and led to an enlarged vesicle structure in comparison with the SP286 control strain. These results strongly suggest that the vesicle-mediated transport process might be another action mechanism of the ER-independent antifungal or cytotoxic effects of TAM.