• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2833-2838
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• 2015

Background: Repeating a prior chemotherapy (rechallenge therapy) is an option for selected patients with metastatic colorectal cancer, but there is very little evidence in the literature for this approach. Thus, we reviewed our registry to evaluate prognostic factors and survival of patients who received irinotecan and oxaliplatin-based regimens as rechallenge third and fourth-line therapy. Materials and Methods: Patients who received irinotecan-based or oxaliplatin-base regimen as first-line had been rechallenged with third-line or fourth-line therapy. These patients were selected from the database of Turkish mCRC registry archives between October 2006 and June 2013 and evaluated retrospectively for factors effecting progression free survival (PFS) and overall survival (OS) by the Kaplan-Meire and Cox-regression methods. Results: Thirty-nine patients were enrolled. The median duration of follow-up was 36 months (14-68 months). Thirty-one patients (76%) died during follow-up. In terms of rechallenge treatments, 29 patients had received third-line and 10 patients had received fourth-line. Response rate (RR) was found to be 12.9%, with stable disease in 19 (48.7%) patients. The median PFS was 6 months (95%CI=4.64-7.35 months) and the median OS was 11 months (95%CI=8.31-13.68 months). The factors effecting survival (PFS and OS) were only being PFS after first-line chemotherapy ${\geq}12months$ (p=0.007, 95% CI=1.75-35.22 and p=0.004, 95%CI=1.44-7.11), both in univariate and multivariate analyses. Conclusions: This study indicates that rechallenge treatment could be a good option as a third or later line therapy in patients who had ${\geq}12months$ PFS onreceiving first line therapy.

• Journal of Korea Society of Industrial Information Systems
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• v.10 no.4
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• pp.65-77
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• 2005

This study aims at providing the basis for improving the applicability of ERP system in those companies which plan to introduce it or those which already introduced, but were not able to achieve the intended effect. To this end, this study focused on the empirical study to find innovation acceptance factors effecting innovation diffusion of ERP system intensively and to search the best path of innovation diffusion. Thus, it was known that innovation characteristics factors, percieved ease of use, perceived usefulnessand implementation of ERP system affected innovation diffusion directly or indirectly and there was a significant path helping companies introduce information system successfully.

• Journal of Korean Academy of Nursing
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• v.34 no.1
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• pp.141-149
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• 2004

Purpose: To identify the status of regular cervical cancer screening practices among middle-aged women, the associations between regular practice and research factors, and the predictive model and factors effecting such behavior was studied. Method: Two hundred women, aged 40 to 60, were selected by convenience in one urban area of Seoul. They were asked about their regular attendance for screening, knowledge of cancer and screening, health belief, health self-determination index and certain personal factors. Result: Approximately 54.5% of the women had periodic screening tests every 6 months to 2 years. Their knowledge of cervical cancer and health belief were at the medium level of each scale, but their health self-determination scores (HSDI) were low. Some influencing factors, and their cancer odds ratio were identified through univariate regression analysis. These variables were included in a predictive model, and this model proved to have enough fit and classification power (83.5%). In this model, the financial state, self-belief and self-determination scores were found to be significant. Conclusion: Middle-age women's intrinsic motivation for healthy behavior was found to be low in those who felt to be in a poor financial state, had higher perceived barriers, lower perceived benefits and a lower prevalence of undergoing regular screening test.

• Journal of Preventive Medicine and Public Health
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• v.40 no.5
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• pp.351-362
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• 2007

Objectives: The present study was intended to assess the mental health of nurses working for university hospitals and to establish which factors determine their mental health. Methods: Self-administered questionnaires were given to 1,486 nurses employed in six participating hospitals located in Daejeon City and Chungnam Province between July 1 st and August 31st, 2006. The questionnaire items included sociodemographic, job-related, and psychosocial factors, with job stress factors (JCQ) as independent variables and indices of mental health status (PWI, SDS and MFS) as dependent variables. For statistical analysis, the Chi-square test was used for categorical variables, with hierarchical multiple regression used for determining the factors effecting mental health. The influence of psychosocial and job-related factors on mental health status was assessed by covariance structure analysis. The statistical significance was set at p<0.05. Results: The factors influencing mental health status among subject nurses included sociodemographic characteristics such as age, number of hours of sleep, number of hours of leisure, and subjective health status; job-related characteristics such as status, job satisfaction, job suitability, stresses such as demands of the job, autonomy, and coworker support; and psychosocial factors such as self-esteem, locus of control and type A behavior patterns. Psychosocial factors had the greatest impact on mental health. Covariance structure analysis determined that psychosocial factors affected job stress levels and mental health status, and that the lower job stress levels were associated with better mental health. Conclusions: Based on the study results, improvement of mental health status among nurses requires the development and application of programs to manage job stress factors and/or psychosocial factors as well as sociodemographic and job-related characteristics.

• Korean Journal of Veterinary Research
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• v.47 no.2
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• pp.139-145
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• 2007

Measurement uncertainty could play an important role in the assessment of test results in laboratories and industries. We investigated measurement uncertainties possibly included in determination of flubendazole, a benzimidazole anthelmintic, in pork by HPLC. The concentration of flubendazole was 62.69 ng/g in a sample of pork. Uncertainty was estimated in the analytical procedure of flubendazole. A model equation was made for determination of flubendazole in pork. The four uncertainty components such as weight of sample, volume of sample, calibration curve, and recovery were selected to estimate measurement uncertainties. Standard uncertainty was calculated for each component and all the standard uncertainties were combined. The combined standard uncertainty was expanded to a sample population as an expanded uncertainty. The expanded uncertainty was calculated using k value on Student's t-table and effective degrees of freedom from Welch-Satterthwaite formula. The expanded uncertainty was calculated as 3.45 with the combined standard uncertainty, 1.584 6 and the k value, 2.18. The final expression can be ($62.69{\pm}3.45$) ng/g (confidence level 95%, k = 2.18). The uncertainty value might be estimated differently depending on the selection of the uncertainty components. It is difficult to estimate all the uncertainty factors. Therefore, it is better to take several big effecting components instead of many small effecting components.

• Journal of the Korean Society of Clothing and Textiles
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• v.23 no.2
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• pp.196-207
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• 1999

The purpose of this study was to investigate the differences of the visual evaluation for the Picture image combination of Clothing and Ground. The major finding were as follows ; 1) For the visual evaluation of the Picture image as Clothing variation there were significant differences in all factors 2) For the visual evaluation of the Picture image as Ground variation there were significant differences in Attractiveness Hardness and softness Cuteness Attention Cool and Warm factor 3) For the visual evaluation of the Picture image as Percentage of Clothing there were significant differences in Attractiveness cool and Warm factor. It will Percentage of Clothing there were significant differences in Attractiveness Cool and Warm factor. It will aid in choosing the most beneficial background for any clothing brand. It will enhance the picture images to their full potential in any advertising medium 4) As a result of Regression analysis image effecting on " Preference" is refined-country like harmonious-inharmonious comfortable-uncomfortable beautiful-ugly splendid-dull stable-uneasy live-gentle 5) For the Image effecting on "Harmony" according to clothing image there were significant differences. the results analyzed according to the change of background are as follows. Mdern and strong images formed charming urban and cool visual images with urban and neat artificial backgrounds. Mature images were created with romantic and static artificial backgrounds. Mannish straight and conservative images created charming and rigid visual images in urban and formatted artificial background. Using a white natural background for the urban style created a cool visual image. The use of an interior background lead to warmer images and more defination lines Causal images created a rural and warm image which expressed charm and a soft visual while using a rural and natural background. A most unharmonious and hard image was created when using an urban and formatted artificial background. The coolest visual image was created with a cool and natural background. Feminine and flawless images created urban and neat visual image using an urban and formatted artificial background. The coolest visual image was fresh created with a cool and natural background. natural background.

• Journal of Korean Academy of Nursing
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• v.35 no.1
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• pp.87-94
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• 2005

Purpose: The purpose of this research was to provide basic data in the control of depression found in patients with fibromyalgia by analysing the main factors that affect them. Method: The subjects were 207 out-patients in three university medical centers diagnosed with fibromyalgia according to the conditions by American College of Rheumatology (1990). Depression was measured by the CES-D Scale. Dependant variables, such as stress and anxiety were measured by the VAS Scale and physical activity was measured using 10(4-point-scale) questions developed by the researcher. The number of tender points was converted to scores based on the criteria of the ACR(1990) and of Yunus. Self-efficacy was measured by the Self-Efficacy Scale developed by Lorig et al. (1989) for arthritis patients. Result: The main factors that affect depression of patients with fibromyalgia were self-efficacy, anxiety, physical activity, tender points fatigue, and family support, which explained 49% of the depression. Conclusion: It has been confirmed that the regression equation model of this research may serve as a predictor of depression in patients with fibromyalgia.

• Journal of Korean Society for Quality Management
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• v.32 no.4
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• pp.15-29
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• 2004

This paper is interested in analyzing the CSFs of 3 different kinds of on-line digital products. They are on-line digital products of (1) transaction, (2) relations, and (3) interests. This study first tried to define the on-line digital products based in the above three categories and then to find the factors that might effect the customer acceptability in each product groups. Independent variables used in this study are characters of products, characters of users, and system environments. This paper that on-line survey has been conducted for the study's specialty and the collected resource was analyzed by using the SPSS 10.0K statistics package. Using multiple regression, this study finds that major factors effecting the user acceptability of each group are different from one another. For example, system environment variables such as speediness, system performance effects the customer acceptability of digital products of Interest(game, avartar, etc). Much more then that of products of relations(information service, etc). Therefore empirical findings are suggested in the conclusion.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.11a
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• pp.25-31
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• 2005

The decommissioning cost estimation is the very essential procedure to establish the decommissioning plans for Nuclear Research Facilities. The cost estimation must be made in accordance with activity phase and facility installations. This paper shows how to configuring the cost items and identifying the effecting cost factors. In the end, these methods will be utilized as a tool and technique to develop the methodology of cost estimation and calculation program.

• Journal of Distribution Science
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• v.18 no.3
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• pp.67-76
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• 2020

Purpose: Consumers are affected by the purchase of a large number of opinions or support during the online purchasing process. This can be defined as the term of 'social decisions' on line. This paper seeks to explore the factors of influence on social decisions in on-line environment and to study in depth. Methodology: The purpose of this paper is to empirically examine the impact of factors on online social decisions. To verify the hypothesis of study, This study collected 256 from Seoul City, Gyeonggi Province and Chungcheong Province through Survey. Results: According to the research results, First, eWOM information usefulness have a positive impact on online social decisions, Second, online network connectedness have a positive impact on online social decisions. Third, innovative product have a positive impact on online social decisions. and the lower the category of knowledge, the more inclined it is to make online social decisions. Finally, social decisions have a positive impact on purchasing decisions about product. It is most significant that academic research has advanced consumer behavior in response to recent changes in the consumption environment. It is meaningful that we have studied in depth the changing consumer decision process in online channel environment.