• Journal of People, Plants, and Environment
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• v.23 no.3
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• pp.363-375
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• 2020

Background and objective: Recreation or activities in forest are regarded as therapy. Many forest therapy programs have been developed and assessed in the domestic. This study was conducted to investigate the effect of the forest therapy program on academic and job-seeking stress in college students. Methods: Thirty five subjects were selected as the experimental group and 25 as the control group, and 29 subjects in the experimental group and 11 in the control group participated in the follow-up test to verify the persistence of stress reduction effects. The forest therapy program was carried out once a week for 2 hours each from September 4 to December 4, 2018, adding up to total eight sessions. Results: The experimental group showed statistically significant reduction in both academic stress and job-seeking stress, whereas the control group did not. For the persistence of the forest therapy program, the experimental group did not show a statistically significant difference between the posttest and the follow-up test, and thus the stress reduction effect was maintained. Conclusion: This study proved the reduction of academic and job-seeking stress in forest therapy programs and the persistence of the stress reduction effect of the forest therapy program. The result is consistent with the Stress Recovery Theory (SRT) that shows the stress reduction effect of nature. In addition, it has significance in that it has verified that the program using the forest on campus can reduce stress of most college students.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.4
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• pp.1-11
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• 2019

Purpose : This study was aimed at investgating the effect of McKenzie exercise on temporomandibular joint disorder (TMJD) and body balance. Methods : Thirty subjects with TMJD were selected. They were randomly assigned to one of two groups (15 in each group) : namely the conservative treatment group and McKenzie exercise group. The conservative treatment group were treated physical therapy for 6 weeks (3 times a week). The McKenzie exercise group performed McKenzie exercise for 6 weeks (3 times a week). We measured mouth opening, pain, muscle activation and body balance before and after exercise by using the maximum mouth opening MMO), visual analog scale (VAS), electromyography and Biodex Balance System, respectively. Results : We found statistically significant differences in pain and mouth opening in the conservative treatment group and McKenzie exercise group before and after (p<.05). Conclusion : We confirmed the effect of McKenzie exercise on TMJD. Thus we thought these results could be used as basic data and reference for TMJD. But we need more study effect of McKenzie exercise on TMJD and body balance.

• Journal of Veterinary Clinics
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• v.21 no.4
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• pp.374-397
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• 2004

This experiment was designed to investigate the analgesic effect of non-invasive electroacupuncture treatment on femoral head osteotomy in dogs. Twelve dogs were divided into 3 groups in this experiment. Electroacupuncture group was non-invasively electrostimulated in Huan Tiao (GB-30) acupoint for 10 minutes by 4.5V, 5Hz for 10 days. Medication group was treated with carprofen (4mg/kg, P.O.) for 10 days. Control group was not treated. Each group was pre-operatively and post-operatively scored by using VAS (Visual Analogue Scale), SDS (Simple Descriptive Scale), NRS (Numerical Rating Scale), and measured serum cortisol levels. The results of VAS, SDS and NRS in electroacupuncture and medication groups were better than those of control group. And, the results of electroacupuncture group were better than those of medication group since 6th day after osteotomy in pain management(p<0.05). But, there were no significances in serum cortisol level among 3 groups. In conclusion, non-invasive electroacupuncture treatment showed sufficient analgesic effect on postoperative pain management after femoral head osteotomy, and VAS, SDS, and NRS scoring system would be adapted in evaluation of pain management.

• The Journal of Internal Korean Medicine
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• v.24 no.1
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• pp.21-32
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• 2003

Objective : The aim of this study is to investigate the inhibitory effect of Injinchunggantang on hepatic sclerosis induced by $CCl_4$. Methods : Weight, liver function test and complete blood cell count, gross findings, and findings on liver tissue of the past(Hematoxylin & Eosin stain, Masson-Trichrome stain) were studied. Results : When it comes to the change of rats' body weight, The $CCl_{4^+}$Injinchunggantang group lost far less weight than The $CCl_{4^-}$only group. In the liver function test, which is focused on various areas such as total cholesterol, alkaline phosphotase, albumin, aspartate transaminase, alanine transaminase, The $CCl_{4^+}$Injinchunggantang group was much more closer to normal limit than the $CCl_4$ only group. In the complete blood cell count, including white blood cell, red blood cell, hemoglobin, hematocrite, platelet, The $CCl_{4^+}$Injinchunggantang group significantly closer to normal limit than $CCl_{4^-}$only group. In the gross findings of hepatic fibrosis models, Injinchunggantang showed inhibitory effect on hepatic fibrosis in the order. In the past findings of hepatic fibrosis models in Hematoxylin & Eosin, Masson-Trichrome staining, the liver in $CCl_{4^-}$only group showed atrophy and necrotic change with white nodules, whereas that of $CCl_{4^+}$Injinchunggantang group showed lesser significant change with the well_preserved tone of the tissue. In the extent of the inhibition of the hepatic fibrosis, the Injinchunggantang group showed statistically significant inhibitory effect(p<0.05) in the sclerosis model. Conclusions : These results show that Injinchunggantang have inhibitory effect on hepatic sclerosis induced by $CCl_4$ and further ultimately prevent liver cirrhosis. To obtain more credible results in this experiment, the invention of a new experimental model more similar to human hepatic sclerosis is still needed.

• Women's Health Nursing
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• v.16 no.1
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• pp.87-94
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• 2010

Purpose: The purpose of this study was to examine the effects of a 16-week Self-help Tai Chi for Arthritis (SHTC) combined with health education for Korean American older women. Methods: This research was a designed quasiexperimental pre-posttest. Forty one women aged 55~79 were recruited 20 in SHTC group 21 in control group and, but twelve in SHTC group and thirteen in control group were left after 16 weeks. SHTC group was educated for 1 hour health education and 1hour TCA, once a week during 16 wks. Measurements for comparison were taken three times, at baseline, 8 wks and 16wks. The effect were evaluated with self-efficacy, shoulder flexibility, back flexibility, both hand grip strength and standing balance with closed eyes. Results: All variables except for left hand grip strength at baseline had significant homogeneity between both groups. After 16 weeks intervention, there was a significant interaction effect of time and group on right hand grip strength by repeated measure of ANOVA (F=3.398, p=.044). No significant interaction effects were found on self-efficacy, shoulder and back flexibility, left hand grip strength and standing balance with closed eyes. Conclusion: I can suggest this self-help Tai Chi program may be effective partially, but further research is needed to establish the best times and periods to intervene for a better effect.

• Journal of Korean Academy of Nursing
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• v.34 no.7
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• pp.1362-1371
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• 2004

Purpose: This study was to examine the effect of an obesity management program on the body weight, body-mass index, and physiological index of obese female high school students. Method: Students from one school were selected as the experimental group, and students from another school as a control group so the latter group wasn't exposed to the experiment. The experimental group and the control group were each organized with 20 students. The experimental group received 60 minutes of behavior modification once a week, for eight weeks. Result: The Body weight, and Body mass-Index of the experimental group significantly decreased after the obesity management program. Total-cholesterol, T-G, and LDL-C significantly decreased and HDL-C increased in the experimental group. Total-cholesterol, T-G, LDL-C and HDL-C between the experimental group and control group showed significant differences. Conclusion: These results indicate that the obesity management program had a great effect on decreasing the body weight and body-mass index of the female obese high school students, normalizing their physiological index. In conclusion, this program turned out to be one of the safest and most effective obesity-management methods that could be applied to female high school students.

• Women's Health Nursing
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• v.9 no.3
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• pp.224-234
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• 2003

Purpose: This study was to test the effects of a full body massage on labor pain and delivery stress reaction for primipara during labor. Method: This study employed a quasi- experimental method(nonequivalent control group, pre-post test design). The subjects of this study were 57 primipara hospitalized at the U OB & GYN hospital in Inchon from November 1. 2001 to July 31, 2002. 28 women were assigned to the experimental group and 29 to the control group. The experimental group was given 20 minutes full body massage for each of three delivery phases. The control group was given conventional delivery care. The levels of labor pain were measured by the Visual Analogue Scale and the expression scores of the labor pain and the levels of delivery stress reaction were measured by pulse rate, respiration rate, and blood pressure, and State-Anxiety Scale. Data were analyzed using the repeated measures analysis of covariance(ANCOVA), t-test, $X^2$- test, simple ANCOVA with SPSS program. Result: There was no interaction effect between time and group(F=.370, p=.693), but significant time effects were found for subjective labor pain(F=3.840, p=.028). There was no interaction effect between time and group(F=.112, p=.894), but significant group effects were found for objective labor pain(F=12.299, p=.001). There was no interaction effect between time and group for PR(F=.172, p=.843), RR(F=.626, p=.539), SBP(F=.089, p=.915), DBP(F=.748, p=.479), but significant group effects were found for SBP(F=7.547, p=.008). The level of status anxiety of the experimental group was significantly lower than the control group(F=11.787, p=.001). Conclusion: This study showed that the full body massage has partially positive effect on labor pain and delivery stress reaction. Therefore this study suggested that the full body massage might be used clinically to help primipara during labor.

• Journal of Ginseng Research
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• v.18 no.1
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• pp.1-9
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• 1994

Sprague-Dawley rats were given freely with 15% ethanol (control) and 15% ethanol containing (1) 0.1% ginseng saponin, (2) 0.02% ginsenoside $Rb_1$, and (3) $Rg_1$ (tests) instead of water for 7 days and aldehyde dehydrogenase (ALDH) and monoamine oxidase (MAO) activity in different regions of brain were examined. In control group, total ALDH activity with indoleacetaldehyde and acetaldehyde as substrate in all different regions was lower than that of normal group except in the hippocampus. The inhibitory effect on the activity was prominent in the corpus striatum and was not in the hippocampus. However, low-$K_m$ ALDH activity in all different regions was much lower than that of normal group. A considerable decrease in mitochondria ALDH activity in cerebellum and striatum was also observed in control group. In test groups total, low-$K_m$, and mitochondria AkDH activities in all different regions were higher than those in control group. Although ALDH activity in the striatum of test group was higher than control group, it was relatively depressed as compared with normal. There was not found a remarkable difference in extent of stimulating effect on the AkDH activity according to the ginseng saponin components. When biogenic aldehydes were used as substrate, ALDH activity with 3,4-dihydroxy-phenylacetaldehyde (DOPAL) in all brain regions of control group was lower than that using 5-hydroxy-indoleacetaldehyde (HIAL) and 3,4-dihydroxyphenylglycolaldehyde (NORAL) as substrate. In control group, ALDH activity with biogenic aldehydes above mentioned was markedly inhibited in the striatum contrary to other regions. The higher ALDH activity with biogenic aldehydes in test group than in control was found in the striatum, cerebrum, and cerebellum. MAO activity in the cerebellum was inhibited in control group and slightly increased in test group. The results of present study suggest that the corpus striatum is significantly affected by ethanol exposure while the hippocampus is not and that ginseng saponin fraction and ginsenosid es might have a preventive effect against depression of brain ALDH activity by chronic administration of ethanol.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.5
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• pp.849-856
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• 2011

This study was investigated the protective effect of Cultivated Wild Ginseng(WG) on the toxicities induced by cyclophosphamide(CP) in mice. Twenty-four male BALB/c mice were divided into non-treated normal group(n=6), CP treated control group(n=6), CP+WG treated CP+WG group(n=6), WG treated WG group(n=6). CP(100 mg/kg of b.w., i.p) was injected at 0, 7 th, 14 th, 21 th, and 28 th day of the experiment respectively. WG(4.4 g/kg, i.p.) was administrated for 35days. Body and organ(heart, liver, kidney, testis) weight were measured. Histopathological examination on the organ(heart, liver, kidney, testis), morphometric analysis, and BrdU immunohistochemistry on the testis were performed. Body weight was decreased following CP administration. In contrast, such a decrease was significantly attenuated by WG administration. CPK and AST of CP+WG group were significantly decreased compared with CP group. Histopathologically, cross sectional area of testis and diameter of seminiferous tubule were significantly increased in CP+WG group compared with CP group. BrdU labelled cells in the seminiferous tubules were remarkably decreased in CP group. Whereas the number of seminiferous tubules labelled with BrdU in spermatogonia was increased by CP+WG administration. The obtained results suggest that WG has protective effect on CP-induced toxicity. This effect might be mediated through the supplementation of vital energy.

• The Korea Journal of Herbology
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• v.24 no.2
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• pp.29-37
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• 2009

Objectives: The goal of this study was to investigate the antidepressive effect of Bupleuri Radix (BR). Methods : The forced swimming test (FST) was performed. Also the expression of corticotropin releasing factor (CRF), c-Fos and tyrosine hydroxylase (TH) was measured immunohistochemically at paraventricular nucleus (PVN) and locus coeruleus (LC). Concentration of adrenocorticotrophic hormone (ACTH) was measured in plasma by ELISA method. Results : The immobility in BR400 Group was significantly decreased in comparison with the control group (p