• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7105-7112
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• 2014

In this study, we investigated oxidative stress and tumor marker levels of polycyclic aromatic hydrocarbons (PAHs) in 136 coke oven workers and in 60 control subjects, and evaluated the correlation between oxidative stress and tumor marker levels. Questionnaires on basic demographic information were also administered. Significant differences in employment time and percentages of alcohol drinkers were observed between the control and exposed groups. PAH exposure was assessed using urinary 1-hydroxy-pyrene (1-OHP) levels and was found to be significantly higher in workers than in the controls. Significant differences (P<0.001) of MDA, GST, LDH, NSE, Cyfra21-1, and of SCC and TNF-a (P<0.0001 and P<0.05, P<0.001, respectively) levels were observed among controls and coke-oven workers, except for bottom coke oven workers. Associations between age and risk of increased TNF-a, smoking and increased GST activities, and drinking with increased MDA concentrations, were marginal (P=0.055, P=0.048, P=0.057, respectively). The association between smoking with MDA (P=0.004), NSE (P=0.005), SCC (P=0.004) andTNF-a (P<0.001), and drinking with TNF-a levels was significant (P=0.012). In addition, a significant positive correlation between oxidative stress and tumor markers was found in the present study. These results suggest that a synergistic increase of oxidative stress and tumor markers induced by PAHs may play a role in toxic responses for PAHs in coke oven workers.

• Journal of Preventive Medicine and Public Health
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• 제53권6호
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• pp.387-396
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• 2020

Objectives: The lack of advance planning in a public health emergency can lead to wasted resources and inadvertent loss of lives. This study is aimed at forecasting the needs for healthcare resources following the expansion of the coronavirus disease 2019 (COVID-19) outbreak in the Republic of Kazakhstan, focusing on hospital beds, equipment, and the professional workforce in light of the developing epidemiological situation and the data on resources currently available. Methods: We constructed a forecast model of the epidemiological scenario via the classic susceptible-exposed-infected-removed (SEIR) approach. The World Health Organization's COVID-19 Essential Supplies Forecasting Tool was used to evaluate the healthcare resources needed for the next 12 weeks. Results: Over the forecast period, there will be 104 713.7 hospital admissions due to severe disease and 34 904.5 hospital admissions due to critical disease. This will require 47 247.7 beds for severe disease and 1929.9 beds for critical disease at the peak of the COVID-19 outbreak. There will also be high needs for all categories of healthcare workers and for both diagnostic and treatment equipment. Thus, Republic of Kazakhstan faces the need for a rapid increase in available healthcare resources and/or for finding ways to redistribute resources effectively. Conclusions: Republic of Kazakhstan will be able to reduce the rates of infections and deaths among its population by developing and following a consistent strategy targeting COVID-19 in a number of inter-related directions.

• 실천공학교육논문지
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• 제11권2호
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• pp.231-237
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• 2019

본 연구의 목적은 대학의 취업지원 프로그램 참여자와 비참여자 간에 구직효능감과 성격 5요인에 차이가 있는지를 규명하는 데 있다. 이를 위해 경북지역에 소재한 D대학교 재학생 382명을 대상으로 연구를 진행하였으며, 취업지원 프로그램 참여자와 비참여자 간에 차이를 검증하였다. 분석 결과는 다음과 같다. 첫째, 취업지원 프로그램 참여자의 구직효능감이 비참여자에 비해 더 높은 것으로 나타났다. 둘째, 취업지원 프로그램 참여자와 비참여자 간 성격 5요인에 따른 차이가 발견되었다. 성격 5요인 중 외향성, 친화성, 성실성은 취업지원 프로그램 참여자가 비참여자에 비해 높게 나타났던 반면, 신경증과 개방성에 따른 차이는 유의하지 않은 것으로 나타났다. 본 연구결과는 성격적 특성이 취업지원 프로그램 참여 여부에 영향을 미칠 수 있음을 시사함으로써 취업지원 프로그램 미 참여 집단이 취업지원 프로그램에 참여하도록 독려하기 위한 방안 마련이 필요함을 보여 주였다.

• Asian-Australasian Journal of Animal Sciences
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• 제19권9호
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• pp.1234-1239
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• 2006

Murrah and NiliRavi are the important North Indian buffalo breeds occupying the prominent position of being the highest milk producers. These breeds are more or less similar at morphological as well as physiological levels. The technique of RAPD-PCR was applied in the present study to identify a battery of suitable random primers to detect genetic polymorphism, elucidation of the genetic structure and rapid assessment of the differences in the genetic composition of these two breeds. A total of 50 random primers were screened in 24 animals each of Murrah and NiliRavi buffaloes to generate RAPD patterns. Of these, 26 (52%) primers amplified the buffalo genome generating 263 reproducible bands. The number of polymorphic bands for the 26 chosen RAPD primers varied from 3 (OPG 06 and B4) to 26 (OPJ 04) with an average of 10.1 bands per primer and size range of 0.2 to 3.2 kb. DNA was also pooled and analyzed to search for population specific markers. Two breed specific RAPD alleles were observed in each of Murrah (OPA02 and OPG16) and NiliRavi (OPG09) DNA pools. RAPD profiles revealed that 11 (4.2%) bands were common to all the 48 individuals of Murrah and NiliRavi buffaloes. Pair-wise band sharing calculated among the individual animals indicated considerable homogeneity of individuals within the breeds. Within breed, band sharing values were relatively greater than those of interbreed values. The low genetic distance (Nei's) value (0.109) estimated in this study is in accordance with the origin and geographical distribution of these breeds. The RAPD analysis indicated high level of genetic similarity between these two important North Indian buffalo breeds.

• 간호행정학회지
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• 제4권2호
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• pp.405-418
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• 1998

The purpose of this study was to describe patients satisfaction with nursing care in the emergency department and factors influencing satisfaction rates. 1. The mean score of patient satisfaction with nursing care in the emergency departments was 2.70. The mean scores of patient satisfaction with different aspects of nursing care services were 3.05 for nursing services for psychological safety: 2.67 for technical competence: 2.49 for information giving: and 1.35 for discharge teaching. 2. Patient satisfaction with nursing care services provided. according to the general characteristics of the patients. was revealed as being significantly high for the groups of patients made up of those who were male. those over 51years of age. married subjects. those with an education level of high school or below level. housewives. Buddhists. and those in the middle economic level. Patient satisfaction with nursing care according to their service utilization in the emergency departments revealed that satisfaction was significantly high for patients who were in internal medicine. neurology or psychiatry. those admitted for the first time. those for whom the distance from the department to home was less than 30 minutes. patients who visited between monday and Friday and between 8AM and 4PM. patients who did not have to wait to be seen and those who stayed in the department less than 24 hours. 3. The correlation between the patients' general characteristics. nursing service utilization of the patients in the department and their satisfaction with nursing care showed that patients with longer waiting time had lower satisfactory scores for nursing service. 4. The registered nurses working in the emergency department reported that the main reasons for low satisfaction rates included 'over worked nurses' and 'too many patients' in the emergency department. In conclusion. the results of this study suggest the necessity of developing relevant nursing interventions for discharge teaching to increase patient satisfaction with nursing care services in emergency departments: and the need for adequate support from hospital administrators to improve patients' service utilization.

• 동의신경정신과학회지
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• 제14권1호
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• pp.17-26
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• 2003

Objective : The clinical efficacy of Jowiseungchungtang(oriental herbal medication) over 6-month on the cognitive function in patients with mild Dementia of Alzheimer type(DAT) was investigated in this study. Method : The subjects for this study consisted of dementia patients who visited to the outpatient dementia department of Oriental Neuropsychiatry of the Kyunghee Oriental hospital. Patients were required to have at entry: a dignosis of mild DAT; Biochemical test, CBC, Urine analysis, Chest X -ray, EKG, Brain- MRI, Mini-Mental States-Korea(MMSE-K), Korean-Dementia Rating Scale(K-DRS), Samsung Dementia Questionaire(SDQ;to their caregiver). Patients(n=31) were assigned to treatment with Jowiseungchungtang (fourth/day for 6-month). The primary outcome measure was K-DRS. Result : 1. Patients' mean age was $71.4{\pm}6.6$ years(range 59 to 86 years). 2. Patients' mean education was $6.1{\pm}4.9$ years. K-DRS scores at baseline was $110.5{\pm}12.2$. K-DRS scores at 6-month was $109.0{\pm}17.0$. K-DRS scores at 6-month was not significantly different with K-DRS scores at baseline(t=.791 r=.435 p<.05). Conclusion : Treatment with Jowiseungchungtang for 6-month protected the cognitive function decline in patients with mild DAT.

• 동의신경정신과학회지
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• 제24권3호
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• pp.211-228
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• 2013

Objectives : This report describes the diagnostic and therapeutic procedures of Collaborative Practice between Korean Traditional Medicine and Western Medicine for two dementia patients. Furthermore, through these cases, we suggest a model of collaborative practice between Korean traditional medicine and western medicine for the treatment of dementia. Methods : Two patients suffering from several symptoms related to dementia received collaborative practice between Korean traditional medicine and western medicine. Physicians of deparment which paient first visit interviewed patient and patient's guardians, discussed the symptoms and the status of the patient. Since then, the medical team made a differential diagnosis based on the results of brain imaging, hematology, urine test. and apprehended the status of dementia by the neuropsychological test. Korean traditional physicians examined the physical symptoms and identified the pattern of dementia in Korean traditional medicine. Following this, they decided on the method of acupuncture, moxibustion, cupping and herbal treatment. Western physicians decided on the type of medication after consideration of the patient's other medical conditions. Every intervention was decided by both Korean traditional physicians and western physicians after discussion. The medical team provided education on dementia and counseled the guardians. They also wrote the paper for using the long-term care insurance for the aged. Results : Two patients showed no improvement on the neuropsychologic and activity of daily living tests. However, the patients' subjective physical symptoms were improved. The collaborative practice between Korean traditional medicine and western medicine improved the patients' and guardians' satisfaction. Conclusions : Through these cases, we propose a model of collaborative practice between Korean traditional medicine and western medicine for dementia categorized diagnosis-test, treatment, prevention, management. More specifically, we supplement qigong and psychotherapy which was inadequate in these cases.

• 간호행정학회지
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• 제3권1호
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• pp.65-82
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• 1997

The purpose of this study was to investigate the role expectation of Clinical Nurse Specialist(CNS) in A tertiary-affiliated hospital in Seoul. Data were surveyed from Jul. 8, to Jul. 20, 1996. 74 medical doctors and 119 nurses participated in this survey. For data analysis, SPSS/PC+ program was used: ${\chi}2-test$, t-test, ANOVA. The difference was analyzed by the subjects' position and department. The results of this study were summarized as follows: 1. The perception about the CNS system : Most of the subjects of study perceived that the introduction of CNS system was needed. And the introduction time of CNS system was demanded as fast as possible, or after special preparation. 2. The comparison of the need for the subroles of the CNS in A tertiary-affiliated hospital : The need for the subroles(0=not known, 1=not needed to 4=absolutely essential) was significantly different between medical doctors and nurses. The total mean scores for degree of need for each subole were as follows: Education 3.37, Consultant 3.34, Researcher 3.29, Direct care provider 2.86. 3. The comparison of the percent of time spent in A tertiary-affiliated hospital : The percent of time spent was significantly different between medical doctors and nurses. The total mean percent of time spent in the five subroles was as follows: Direct care provider 34.9%, Educator 23.9%, Researcher 18.9%, Consultant 12.8%, and Management/Change agent 9.5% According to the study results, suggestions were made: 1. Further study for the need of the CNS role as direct care provider is needed, after correcting the items within the narrow scope in some clinical department. 2. Development of the detail roles for the extent of autonomy is needed, and validity should be tested. And then they will be used for the basic data of the role development of the CNS.

• 성인간호학회지
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• 제28권4호
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• pp.367-377
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• 2016

Purpose: The purpose of this study was to explore the quality of life (QoL) in patients with Alzheimer's disease (AD) and their and caregivers and its influencing factors. Methods: A descriptive research design was used. 211 pairs of AD patients and their caregivers were recruited from a neurology outpatient clinic of S medical center in Seoul, Korea. Caregivers completed several structured questionnaires regarding AD patients' QoL as well as their QoL, patients' behavioral and psychological symptoms, patients' activities of daily living (ADL), social support, and quality of relationship between AD patients and caregivers. Cognitive status of AD patients was assessed by the researchers using Korean Mini-Mental State Examination. Results: The scores of QoL were 26.91 for AD patients and 85.62 for their caregivers. In the multiple regression, factors associated with AD patients' QoL were the quality of relationship (${\beta}$=.44), ADL (${\beta}$=-.33), patient's age (${\beta}$=.20), caregivers' QoL (${\beta}$=.20), and patient's gender (${\beta}$=.11). Factors associated with caregivers' QoL were the quality of relationship (${\beta}$=.34), relationship (${\beta}$=.32), patient's QoL (${\beta}$=.26), caregivers' gender (${\beta}$=.18), social support (${\beta}$=.12), and the level of caregivers' education (${\beta}$=.12). Conclusion: To improve the QoL in AD patients and their caregivers, strategies to promote their quality of relationship are needed.

• 한국콘텐츠학회논문지
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• 제16권3호
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• pp.649-660
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• 2016

본 연구는 입원 중인 뇌졸중 환자 주돌봄자의 돌봄 부담감, 대처행동, 자아탄력성 및 관계를 파악하기 위한 조사연구이다. 연구대상은 C시 S대학교 부속병원 신경외과, 신경과에 입원한 뇌졸중 환자의 주돌봄자 74명이었고, 자료수집은 2014년 3월 23일부터 9월 30일까지 이루어졌다. 연구결과, 돌봄 부담감은 3.66점, 대처행동은 2.67점, 자아탄력성은 3.10점이었다. 돌봄 부담감은 성별, 연령, 환자와의 관계, 교육수준, 결혼상태, 주관적 건강상태, 대처행동은 결혼상태, 돌봄시간에서 유의한 차이를 보였고, 자아탄력성은 유의한 차이를 보인 변수가 없었다. 돌봄 부담감, 대처행동 및 자아탄력성은 상관관계가 없는 것으로 나타났다. 결론적으로 주돌봄자의 돌봄 부담감은 크며, 돌봄 부담감을 감소시키기 위한 정부 병원 차원의 보호자 없는 병동, 포괄간호서비스 실시와 간호부의 주돌봄자를 위한 상담, 교육, 지지간호가 절실히 필요하며, 세 변수간의 관계를 밝힐 수 있는 반복 연구가 필요하다.