• Title/Summary/Keyword: Ecole Polytechnique

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Biomimetics of the extracellular matrix: an integrated three-dimensional fiber-hydrogel composite for cartilage tissue engineering

  • Coburn, Jeannine;Gibson, Matt;Bandalini, Pierre Alain;Laird, Christopher;Mao, Hai-Quan;Moroni, Lorenzo;Seliktar, Dror;Elisseeff, Jennifer
    • Smart Structures and Systems
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    • v.7 no.3
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    • pp.213-222
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    • 2011
  • The native extracellular matrix (ECM) consists of an integrated fibrous protein network and proteoglycan-based ground (hydrogel) substance. We designed a novel electrospinning technique to engineer a three dimensional fiber-hydrogel composite that mimics the native ECM structure, is injectable, and has practical macroscale dimensions for clinically relevant tissue defects. In a model system of articular cartilage tissue engineering, the fiber-hydrogel composites enhanced the biological response of adult stem cells, with dynamic mechanical stimulation resulting in near native levels of extracellular matrix. This technology platform was expanded through structural and biochemical modification of the fibers including hydrophilic fibers containing chondroitin sulfate, a significant component of endogenous tissues, and hydrophobic fibers containing ECM microparticles.

JPEG Pleno: Providing representation interoperability for holographic applications and devices

  • Schelkens, Peter;Ebrahimi, Touradj;Gilles, Antonin;Gioia, Patrick;Oh, Kwan-Jung;Pereira, Fernando;Perra, Cristian;Pinheiro, Antonio M.G.
    • ETRI Journal
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    • v.41 no.1
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    • pp.93-108
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    • 2019
  • Guaranteeing interoperability between devices and applications is the core role of standards organizations. Since its first JPEG standard in 1992, the Joint Photographic Experts Group (JPEG) has published several image coding standards that have been successful in a plethora of imaging markets. Recently, these markets have become subject to potentially disruptive innovations owing to the rise of new imaging modalities such as light fields, point clouds, and holography. These so-called plenoptic modalities hold the promise of facilitating a more efficient and complete representation of 3D scenes when compared to classic 2D modalities. However, due to the heterogeneity of plenoptic products that will hit the market, serious interoperability concerns have arisen. In this paper, we particularly focus on the holographic modality and outline how the JPEG committee has addressed these tremendous challenges. We discuss the main use cases and provide a preliminary list of requirements. In addition, based on the discussion of real-valued and complex data representations, we elaborate on potential coding technologies that range from approaches utilizing classical 2D coding technologies to holographic content-aware coding solutions. Finally, we address the problem of visual quality assessment of holographic data covering both visual quality metrics and subjective assessment methodologies.

Analysis of Free Vibration Characteristics of Tapered Friction Piles in Non-homogeneous Soil Layers (불균질 지반에 설치된 테이퍼 마찰말뚝의 자유진동 특성 분석)

  • Lee, Joon Kyu;Ko, Junyoung;Lee, Kwangwoo;Kim, Dongwook
    • Journal of the Korean Geosynthetics Society
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    • v.18 no.3
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    • pp.69-77
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    • 2019
  • This paper presents a new analytical model for estimating the free vibration of tapered friction piles. The governing differential equation for the free vibration of statically axially-loaded piles embedded in non-homogeneous soil is derived. The equation is numerically integrated by the Runge-Kutta method, and then the eigenvalue of natural frequency is determined by the Regula-Falsi scheme. For a cylindrical non-tapered pile, the computed natural frequencies compare well with the available data from literature. Numerical examples are presented to investigate the effects of the tapering, the skin friction resistance, the end condition of the pile, the vertical compressive loading, and the soil non-homogeneity on the natural frequency and mode shape of tapered friction piles.

AN EXTENSION OF THE BETA FUNCTION EXPRESSED AS A COMBINATION OF CONFLUENT HYPERGEOMETRIC FUNCTIONS

  • Marfaing, Olivier
    • Honam Mathematical Journal
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    • v.43 no.2
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    • pp.183-197
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    • 2021
  • Recently several authors have extended the Beta function by using its integral representation. However, in many cases no expression of these extended functions in terms of classic special functions is known. In the present paper, we introduce a further extension by defining a family of functions Gr,s : ℝ*+ → ℂ, with r, s ∈ ℂ and ℜ(r) > 0. For given r, s, we prove that this function satisfies a second-order linear differential equation with rational coefficients. Solving this ODE, we express Gr,s as a combination of confluent hypergeometric functions. From this we deduce a new integral relation satisfied by Tricomi's function. We then investigate additional specific properties of Gr,1 which take the form of new non trivial integral relations involving exponential and error functions. We discuss the connection between Gr,1 and Stokes' first problem (or Rayleigh problem) in fluid mechanics which consists in determining the flow created by the movement of an infinitely long plate. For $r{\in}{\frac{1}{2}}{\mathbb{N}}^*$, we find additional relations between Gr,1 and Hermite polynomials. In view of these results, we believe the family of extended beta functions Gr,s will find further applications in two directions: (i) for improving our knowledge of confluent hypergeometric functions and Tricomi's function, (ii) and for engineering and physics problems.

Performance of Various Drug-Eluting Stent Geometries Measured Using Computational Analysis (여러 형상을 고려한 약물분출 스텐트의 성능에 대한 수치해석적 연구)

  • Seo, Tae-Won;Barakat, Abdul I.
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.6
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    • pp.601-607
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    • 2012
  • In this study, we performed computational fluid dynamic simulations to explore how the detailed design of drug-eluting stents affects both the flow field in the vicinity of the stent as well as the concentration of the eluted drug at the endothelial cell surface. Simulations were performed on three idealized stent geometries we developed and on geometries approximating three commercial stents,: Medtronic's Aurora stent, Cordis's BX Velocity stent, and Boston Scientific's Wallstent. An important contribution of the present study is the introduction of the stent effectiveness index (EI), which provides a quantitative assessment of stent performance and an objective basis for comparing the performance of different stents. Among the three commercial stents studied, our simulations have revealed that the BX Velocity stent is associated with the lowest in-stent EI values for the range of flow Reynolds numbers studied ($200{\leq}Re{\leq}800$). In addition to commercial stent designs, we investigated the EI in three idealized stents and determined that a spiral stent provides excellent performance (low EI) under all flow conditions investigated.

Portable Amperometric Perchlorate Selective Sensors with Microhole Array-water/organic Gel Interfaces

  • Lee, Sang Hyuk;Kim, Hyungi;Girault, Hubert H.;Lee, Hye Jin
    • Bulletin of the Korean Chemical Society
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    • v.34 no.9
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    • pp.2577-2582
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    • 2013
  • A novel stick-shaped portable sensing device featuring a microhole array interface between the polyvinylchloride-2-nitrophenyloctylether (PVC-NPOE) gel and water phase was developed for in-situ sensing of perchlorate ions in real water samples. Perchlorate sensitive sensing responses were obtained based on measuring the current changes with respect to the assisted transfer reaction of perchlorate ions by a perchlorate selective ligand namely, bis(dibenzoylmethanato)Ni(II) (Ni(DBM)2) across the polarized microhole array interface. Cyclic voltammetry was used to characterize the assisted transfer reaction of perchlorate ions by the $Ni(DBM)_2$ ligand when using the portable sensing device. The current response for the transfer of perchlorate anions by $Ni(DBM)_2$ across the micro-water/gel interface linearly increased as a function of the perchlorate ion concentration. The technique of differential pulse stripping voltammetry was also utilized to improve the sensitivity of the perchlorate anion detection down to 10 ppb. This was acquired by preconcentrating perchlorate anions in the gel layer by means of holding the ion transfer potential at 0 mV (vs. Ag/AgCl) for 30 s followed by stripping the complexed perchlorate ion with the ligand. The effect of various potential interfering anions on the perchlorate sensor was also investigated and showed an excellent selectivity over $Br^-$, $NO_2{^-}$, $NO_3{^-}$, $CO{_3}^{2^-}$, $CH_3COO^-$ and $SO{_4}^{2^-}$ ions. As a final demonstration, some regional water samples from the Sincheon river in Daegu city were analyzed and the data was verified with that of ion chromatography (IC) analysis from one of the Korean-certified water quality evaluation centers.

Evolution and scaling of a simulated downburst-producing thunderstorm outflow

  • Oreskovic, Christopher;Savory, Eric;Porto, Juliette;Orf, Leigh G.
    • Wind and Structures
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    • v.26 no.3
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    • pp.147-161
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    • 2018
  • For wind engineering applications downbursts are, presently, almost exclusively modeled, both experimentally and numerically, as transient impinging momentum jets (IJ), even though that model contains none of the physics of real events. As a result, there is no connection between the IJ-simulated downburst wind fields and the conditions of formation of the event. The cooling source (CS) model offers a significant improvement since it incorporates the negative buoyancy forcing and baroclinic vorticity generation that occurs in nature. The present work aims at using large-scale numerical simulation of downburst-producing thunderstorms to develop a simpler model that replicates some of the key physics whilst maintaining the relative simplicity of the IJ model. Using an example of such a simulated event it is found that the non-linear scaling of the velocity field, based on the peak potential temperature (and, hence, density) perturbation forcing immediately beneath the storm cloud, produces results for the radial location of the peak radial outflow wind speeds near the ground, the magnitude of that peak and the time at which the peak occurs that match well (typically within 5%) of those produced from a simple axi-symmetric constant-density dense source simulation. The evolution of the downdraft column within the simulated thunderstorm is significantly more complex than in any axi-symmetric model, with a sequence of downdraft winds that strengthen then weaken within a much longer period (>17 minutes) of consistently downwards winds over almost all heights up to at least 2,500 m.

Axisymmetric Swirling Flow Simulation of the Draft Tube Vortex in Francis Turbines at Partial Discharge

  • Susan-Resiga, Romeo;Muntean, Sebastian;Stein, Peter;Avellan, Francois
    • International Journal of Fluid Machinery and Systems
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    • v.2 no.4
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    • pp.295-302
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    • 2009
  • The flow in the draft tube cone of Francis turbines operated at partial discharge is a complex hydrodynamic phenomenon where an incoming steady axisymmetric swirling flow evolves into a three-dimensional unsteady flow field with precessing helical vortex (also called vortex rope) and associated pressure fluctuations. The paper addresses the following fundamental question: is it possible to compute the circumferentially averaged flow field induced by the precessing vortex rope by using an axisymmetric turbulent swirling flow model? In other words, instead of averaging the measured or computed 3D velocity and pressure fields we would like to solve directly the circumferentially averaged governing equations. As a result, one could use a 2D axi-symmetric model instead of the full 3D flow simulation, with huge savings in both computing time and resources. In order to answer this question we first compute the axisymmetric turbulent swirling flow using available solvers by introducing a stagnant region model (SRM), essentially enforcing a unidirectional circumferentially averaged meridian flow as suggested by the experimental data. Numerical results obtained with both models are compared against measured axial and circumferential velocity profiles, as well as for the vortex rope location. Although the circumferentially averaged flow field cannot capture the unsteadiness of the 3D flow, it can be reliably used for further stability analysis, as well as for assessing and optimizing various techniques to stabilize the swirling flow. In particular, the methodology presented and validated in this paper is particularly useful in optimizing the blade design in order to reduce the stagnant region extent, thus mitigating the vortex rope and expending the operating range for Francis turbines.

PHASE-B PRE-SIMULATION USING BORON AND GADOLINIUM AS POISON IN THE MODERATOR SYSTEM FOR WOLSONG-1

  • Kim, Sung-Min;Kim, Hyeong-Taek;Donnelly, Jim;Marleau, Guy
    • Nuclear Engineering and Technology
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    • v.44 no.5
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    • pp.551-560
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    • 2012
  • The Wolsong-1 (W-1) Phase-B pre-simulations were carried out in preparation for tests to be conducted for the restart of the reactor after a major refurbishment project that included replacement of the pressure tube. These pre-simulations for Wolsong-1 Phase-B differ from those in the past that were performed for the Wolsong-1,2,3,4 tests in that these tests use the WIMS/DRAGON/RFSP-IST code suite for verification of the tests and gadolinium instead of the traditional PPV/MULTICELL/RFSP code system and boron as poison in the moderator system. The use of gadolinium is deemed not to have domestically accumulated experience gained from the previous Phase-B tests. Thus, it is appropriate to conduct a study in order to gain a correct understanding and interpretation of potential differences in test results stemming from using gadolinium rather than boron. Although the calibration of the reactivity device will not be noticeably different using boron and gadolinium at a constant moderator temperature, the temperature dependency of the neutronic behavior due to the presence of gadolinium in the moderator system might be pronounced. The results of the pre-simulations using gadolinium revealed that the moderator temperature reactivity coefficients indeed showed significant differences in comparison with those with boron. In order to secure the validity of the analysis results, the newly acquired WIMS/DRAGON/RFSP-IST code suite was verified against the W-2,3,4 Phase-B test results. The results of the new code suite verifications revealed some overall improvements in accuracy; justification of the use of the code can be claimed for the validation of the W-1 Phase-B test results.

Proposed Message Transit Buffer Management Model for Nodes in Vehicular Delay-Tolerant Network

  • Gballou Yao, Theophile;Kimou Kouadio, Prosper;Tiecoura, Yves;Toure Kidjegbo, Augustin
    • International Journal of Computer Science & Network Security
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    • v.23 no.1
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    • pp.153-163
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    • 2023
  • This study is situated in the context of intelligent transport systems, where in-vehicle devices assist drivers to avoid accidents and therefore improve road safety. The vehicles present in a given area form an ad' hoc network of vehicles called vehicular ad' hoc network. In this type of network, the nodes are mobile vehicles and the messages exchanged are messages to warn about obstacles that may hinder the correct driving. Node mobilities make it impossible for inter-node communication to be end-to-end. Recognizing this characteristic has led to delay-tolerant vehicular networks. Embedded devices have small buffers (memory) to hold messages that a node needs to transmit when no other node is within its visibility range for transmission. The performance of a vehicular delay-tolerant network is closely tied to the successful management of the nodes' transit buffer. In this paper, we propose a message transit buffer management model for nodes in vehicular delay tolerant networks. This model consists in setting up, on the one hand, a policy of dropping messages from the buffer when the buffer is full and must receive a new message. This drop policy is based on the concept of intermediate node to destination, queues and priority class of service. It is also based on the properties of the message (size, weight, number of hops, number of replications, remaining time-to-live, etc.). On the other hand, the model defines the policy for selecting the message to be transmitted. The proposed model was evaluated with the ONE opportunistic network simulator based on a 4000m x 4000m area of downtown Bouaké in Côte d'Ivoire. The map data were imported using the Open Street Map tool. The results obtained show that our model improves the delivery ratio of security alert messages, reduces their delivery delay and network overload compared to the existing model. This improvement in communication within a network of vehicles can contribute to the improvement of road safety.