• 당뇨병
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• 제19권3호
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• pp.135-139
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• 2018

The sodium-glucose cotransporter-2 inhibitor (SGLT2i) is a new anti-hyperglycemic agent that have function to concomitantly inhibit the reabsorption of glucose and sodium in the renal proximal convoluting tubule. Recent two cardiovascular outcome trials showed that a lower risk of cardiovascular events with SGLT2i in people with type 2 diabetes. In addition, prior real-world data demonstrated similar SGLT2i effects, but these studies were limited to the United States and Europe. Thus, the CVD-REAL (Comparative Effectiveness of Cardiovascular Outcomes in New Users of Sodium-Glucose Cotransporter-2 Inhibitors) 2 Study was investigated cardiovascular outcomes in those initiated on SGLT2i versus other glucose-lowering drugs (oGLDs) across 6 countries in the Asia Pacific, the Middle East, and North American regions. In Korea, 336,644 episodes of initiation in SGLT2i or oGLD group between September 2014 and December 2016 were identified in Korea National Health Insurance database after propensity score matching. SGLT2i users was associated with a lower risk of all-cause death (hazard ratio [HR], 0.72; 95% confidence interval [CI], 0.67~0.77), hospitalization for heart failure (HHF) (HR, 0.87; 95% CI, 0.82~0.92), all-cause death or HHF (HR, 0.81; 95% CI, 0.78~0.85), myocardial infarction (HR, 0.81; 95% CI, 0.74~0.89), and stroke (HR, 0.82; 95% CI, 0.78~0.86) compared with oGLD users. In conclusion, initiation of SGLT2i had a lower risk of cardiovascular events in people with type 2 diabetes compared with oGLDs.

• Asian Journal of Innovation and Policy
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• 제10권2호
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• pp.195-211
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• 2021

This paper measures the economic impacts of the U.S. port investment strategies coping with the Panama Canal expansion. Using secondary import data, negative and positive estimates of the impacts were presented in this study. Reduced port activities into the West Coast Customs Districts negatively affect transportation and warehousing industries, among other effects. Still, they have simultaneous positive effects in other states from increased imports resulting from modal shifts and changes in the entry port located in the South and East coasts. This study applied the supply-driven National Interstate Economic Model that measures all interstate trade among the U.S. states to divert foreign imports from 15 Pacific Rim countries. For this purpose, the following assumption was adopted: larger ships using the canal will lead to a redirection of seaborne trade among U.S. (and other) ports and result in secondary effects, e.g., using different freight modes and regional growth spillovers. This study also accounted for the entry point change and significant port investments for foreign trade under alternative scenarios. The choice of ports for international trade depends on decisions about how to minimize multimodal delivery costs. The total direct reduction of transportation and warehousing activities associated with foreign imports in the West Coast ports was estimated at $3.3 billion, leading to total negative effects of $5.8 billion. Total positive impacts from the shift of transportation modes with the choice of an entry port and new warehousing activities for foreign imports in the selected 12 states varied. As expected, states that involved an entry port had the most prominent benefits, but Texas, New York, and New Jersey may be benefited through all the port enhancement projects in the U.S. Also, except for Transportation and Postal, and Warehousing industries, Construction is another dominant positive affected industry of the Canal expansion in the U.S.

• 대기
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• 제29권2호
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• pp.115-129
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• 2019

Surface winds over the ocean influence not only the climate change through air-sea interactions but the coastal erosion through the changes in wave height and direction. Thus, demands on a reliable projection of future changes in surface winds have been increasing in various fields. For the future projections, climate models have been widely used and, as a priori, their simulations of surface wind are required to be evaluated. In this study, we evaluate the climatological mean surface winds over the Korean Waters simulated by five regional climate models participating in Coordinated Regional Climate Downscaling Experiment (CORDEX) for East Asia (EA), an international regional climate model inter-comparison project. Compared with the ERA-interim reanalysis data, the CORDEX-EA models, except for HadGEM3-RA, produce stronger wind both in summer and winter. The HadGEM3-RA underestimates the wind speed and inadequately simulate the spatial distribution especially in summer. This summer wind error appears to be coincident with mean sea-level pressure in the North Pacific. For wind direction, all of the CORDEX-EA models simulate the well-known seasonal reversal of surface wind similar to the ERA-interim. Our results suggest that especially in summer, large-scale atmospheric circulation, downscaled by regional models with spectral nudging, significantly affect the regional surface wind on its pattern and strength.

• 한국기후변화학회지
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• 제7권1호
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• pp.49-57
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• 2016

In the present study, the time series of the number of days on which temperatures were not higher than $-5^{\circ}C$ in winter in Seoul was analyzed. The results showed a decreasing tendency until recently. Statistical change-point analysis was conducted to examine whether climate regime shifts existed in this time series. According to the results, the number of days on which temperatures were not higher than $-5^{\circ}C$ in winter in Seoul drastically decreased since 1988. Therefore, to find out the reason for the recent decrease in the number of days, differences between the means of large-scale environments in winder during 1988~2010 and those during 1974~1987 were analyzed. In all layers of the troposphere, anomalous anticyclones developed in regions around the Korean Peninsula and thus the Korean Peninsula was affected by westerlies or south-westerlies. This was associated with the recent a little further northward development of western North Pacific subtropical high. Therefore, environments good for warm and humid air to flow into the Korean Peninsula were formed. To examine whether relatively warm and humid air actually flowed into the Korean Peninsula recently, temperatures and specific humidity in all layers in the troposphere were analyzed and according to the results the Korean Peninsula showed warm and humid anomalies. In the analyses of sensible heat net flux and maximum temperatures at a height of 2 m that can be felt by humans, the East Asia Continent including the Korean Peninsula showed positive anomalies.

• 한국수산과학회지
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• 제54권3호
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• pp.298-310
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• 2021

Freshwater eel Anguilla japonica is a commercially important species in East Asia. However, given the continuously decreasing resources due to many problems as climate change, habitat destruction and overfishing, mass seed production is crucial. In particular, the eel larvae present a unique life history, spending prolonged periods in the Pacific Ocean. Therefore, finding suitable feed that lasts through the long larval stages is rather difficult. In the present study, we histologically observed the development of digestive organs for 50 days after hatching (DAH). The endogenous reserves were completely absorbed at 7 DAH, and the first exogenous feeding started thereafter. The teeth appeared at 4 DAH and dramatically changed from needle-like to broad-based types by 50 DAH. The intestine remained as straight gut until 50 DAH. The intestinal cilia appeared first at 6 DAH and their density continuously increased thereafter. Interestingly, goblet cells appeared in the intestine, but not in the esophagus, where these cells are commonly observed in other teleosts. In addition, high amounts of eosinophil substances, assumed to be zymogen granules, accumulated in the pancreas, suggesting a specific digestive strategy of this species. Overall, these observations largely update the previous reports and can be useful to improve A. japonica seed production.

• 한국수산과학회지
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• 제54권2호
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• pp.188-193
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• 2021

On March 13, 2018 two postflexion larval specimens (18.28 mm and 16.80 mm in standard length) belonging to the family Cryptacanthodidae, suborder Zoarcoidei were collected from Sokcho and Gangneung in Gangwon Province. The family Cryptacanthodidae comprises 4 species worldwide: 3 in the North Pacific Ocean and 1 in the western North Atlantic Ocean. As a result of analyzing 620 bp of the mtDNA COI region, the two postflexion larvae collected in this study were identified as Cryptacanthodes bergi by 99.5% agreement with C. bergi adult registered in NCBI. Postflexion larvae of C. bergi are compressed with large eyes and radial pectoral fins and the anus located in front of the center of the body. Melanophores were intensively distributed along the dorsal midline, except for caudal peduncle, and sporadically distributed on the back of the anus. In addition, there were limited star-like melanophores on the back of the gut. This species showed 0.058 genetic distance when compared mtDNA COI region of C. aleutensis, and it was well distinguished in the distribution pattern of black vesicles of the head, count and measurement traits. Considering the morphological and ecological characteristics of this species, we suggest a new Korean name, " Gwisin-jang-gaeng-i ".

• 한국환경과학회지
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• 제30권12호
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• pp.1067-1079
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• 2021

The coastal water is a space where salmon (Oncorhynchus keta), critical energy-conveying mediator, stay to adapt to different environments while traveling between ocean and river ecosystems for spawning and growth. The mid-eastern coast of Korea (MECW) is the southern limit of salmon distributed in the North Pacific Ocean. Understanding the distribution and migration characteristics of salmon in the MECW is important for the prediction of changes in the amount and distribution of salmon related to changes in the future marine environment. We analyzed the relationship between the salmon migratory timing ascending the Wangpi river and change in vertical seawater temperature and tidal elevation. Overall results highlight that (1) Salmon began to ascend the river when the sea surface water temperature (SST) decreased below 20℃; (2) The number of salmon ascending the river increased when the temperature difference between the upper and lower layers decreased, but decreased when the temperature difference was higher than 5℃; (3) The number of salmon ascending the river peaked, when the SST was 18℃-19℃ and sea levels rose at high tide. This study provide important insight into predicting changes in the ecosystem energy circulation through climate change at its southern distribution limit.

• 대기
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• 제32권3호
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• pp.235-246
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• 2022

A large number of MJO skill metrics and process-oriented MJO simulation metrics have been developed by previous studies including the MJO Working Group and Task Force. To assess models' successes and shortcomings in the MJO simulation, a standardized set of diagnostics with the additional set of dynamics-oriented diagnostics are applied. The Global Coupled (GC) model developed for the operation of the climate prediction system is used with the comparison between the GC2 and GC3.1. Two GC models successfully capture three-dimensional dynamic and thermodynamic structure as well as coherent eastward propagation from the reference regions of the Indian Ocean and the western Pacific. The low-level moisture convergence (LLMC) ahead of the MJO deep convection, the low-level westerly and easterly associated with the coupled Rossby-Kelvin wave and the upper-level divergence are simulated successfully. The GC3.1 model simulates a better three-dimensional structure of MJO and thus reproduces more realistic eastward propagation. In GC2, the MJO convection following the LLMC near and east of the Maritime Continent is much weaker than observation and has an asymmetric distribution of both low and upper-level circulation anomalies. The common shortcomings of GC2 and GC3.1 are revealed in the shorter MJO periods and relatively weak LLMC as well as convective activity over the western Indian Ocean.

• 아태비즈니스연구
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• 제12권3호
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• pp.1-36
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• 2021

Purpose - This empirical study, aims to identify the determinants of adoption and acceptance of mobile payment as to understand why it is successful in some countries in Sub-Saharan Africa but failing in others. A comparative study of a successful mobile payment service and a purported failed one was done as to have some insights to the factors affecting acceptance of the technology. Design/methodology/approach - The strength of three notable theories: theory of diffusion of innovation (DOI), the extended unified theory of user acceptance of information technology (UTAUT2) and self-efficacy theory were use. The self-efficacy of government support inclusion as, a moderating variable in the form of infrastructure, securing transaction and price value revealed the relevance of government in the success of mobile payment service. By means of a field survey of 705 subjects in two separate regions of Africa (East and West), the data was collected and use to test the research model. Findings - The study result shows the importance of the moderating factor of government support to the success of mobile payment of any nation. The result also shows the importance of the perception of relative advantage, compatibility, complexity, social influence as already revealed by other studies. Research implications or Originality - Mobile payment success in some part of Sub-Saharan Africa is well known but also suggested to fail in some Sub-Saharan African countries. Buttressing the need for understanding of the factors affecting mobile payment acceptance. This article empirically examined the factors influencing the success of mobile payment, and we implicated that if the implementation of mobile payment is to be successful for mobile commerce in any nation, adoption, acceptance and use by its citizen is imperative.

• 아태비즈니스연구
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• 제14권1호
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• pp.131-148
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• 2023

Purpose - Since the 2020s, the management philosophy of Chinese firms' ESG has been rapidly established under the leadership of the Chinese government. We empirically analyze the ESG characteristics and effects on corporate value of Chinese firms. Design/methodology/approach - Using OLS and random effect panel regression analysis, we identify ESG determinants. In analyzing the impact on corporate value, likewise a large number of literatures, we adopt a 2SLS methodology using instrumental variables in the reason of endogeneity between ESG and firm value. We analyze using the G2SLS methodology, which is improving the efficiency of the estimation coefficients along with 2SLS. Findings - We find that ESG ratings are high in state-owned and foreign capital invested companies, ESG ratings are low in companies with a high proportion of non-floating stocks which implies information asymmetry. However, there are no significance in the institutional investor's, the major 10 largest shareholders' and manager's ownership. Furthermore, we can support most of the hypotheses that ESG ratings will be high in companies with high management performance. ESG ratings are significantly higher in companies with high ROA, rich in cash asset, low debt ratio, and large size. we strongly support the hypothesis that the higher the ESG rating, the higher the firm value, and ESG has a moderating effect on state-owned companies, non-floating shares, the ownership of institutional investors, manager, and the 10 major shareholder. In particular, state-owned companies, the proportion of non-floating shares, and the ownership of the 10 major shareholders have a negative impact on firm value, however, ESG attenuates this negative effect. Research implications or Originality - This study looks forward to enhancing our understanding of ESG characteristics in East Asia.