Objectives : The application of DNCB (1-chloro-2,4-dinitrochlorobenzene) can cause cellular immunity allergic reaction such as erythema or edema on NC/Nga mice and combinational function of cells participating in immunity increase inflammatory mediator. In this study, the effects of cypress essential oil on NC/Nga mice have been assessed. Methods : Male SPF NC/Nga mice aged 8 weeks have been used for atopic dermatitis induction skin. 1% DNCB was applied on ears and backs of which hair was removed using clipper on $1^{st}$ day and 0.4% DNCB was applied three times a week for 3 weeks. In this study, cypress essential oil has been treated 1 time a day for 3 weeks after application of DNCB to induce atopic dermatitis on skin for further experiments. Results : This study shows that inhalation or application of cypress essential oil reduced edema in ears and the thickness of epidermis induced by DNCB treatment. And it can be known that treatment of cypress essential oil inhibited mast cell proliferation and reduced IgE level similar to that of the negative control especially when cypress essential oil was inhaled by the mice. Synthetic oil showed the effects lower than those of cypress essential oil. Conclusions : Inhalation or direct application of cypress essential oil on skin reduced IgE level in blood and prohibits the proliferation of mast cell, from which it can be known that cypress essential oil can be effectively used to reduce the symptoms of atopic dermatitis.
A Korean local maize line, MET, which has multi-ears and tillers has been proved as a potential source for silage production. However, no fundamental genetic nature for the line has been investigated. Therefore, this study was done to find genetic information on the multi-earing and -tillering habits of MET line. MET line and a hybrid. (Mo 17 ${\times}$ B68), with monoculm and single ear per plant were used for production of F$_1$(F$\_$1-12/ and F$\_$1-21/), F$\_$2-12/, F$\_$2-21/, BC$\_$1-12/ and BC$\_$1-21/ generations. From the comparison of reciprocal crosses, it was found that the tillering and earing habits of the MET line are controlled by cytoplasmic factors. The tiller and ear numbers, and barren ears were all characters associated with the MET cytoplasm. The cytoplasmic effect of MET on tiller and ear numb en was not evident in F$_1$ generation, probably because of suppressing effect of heterosis on appearance of tillers or ears. Genetic parameters for the gene action for both tiller and ear number also indicated a lack of mono- or digenic-chromosomal gene effects. The heritability (broad) was very low for both characters. Therefore, it is strongly concluded that the tillering and earing characters of MET line are due to cytoplasmic reasons.
Kim, Do-Yup;Park, Jin-Hyung;Chun, Bong-Kwon;Han, Yea-Sik
Archives of Plastic Surgery
/
v.38
no.4
/
pp.351-358
/
2011
Purpose: The inflammatory phase is considered an integral part of adult wound healing, but fetal wound healing studies have shown scarless healing results in the absence of the inflammation process. The COX-2 pathway is an essential component of inflammation. The purpose of this study is to identify the effect of a topical selective COX-2 inhibitor on inflammation in rabbit skin wound healing and scarring. Methods: Full-thickness wounds were made on 6 New Zealand rabbits' ears. Topical 5% celecoxib + vehicle (experimental tissue) and vehicle only (controlled tissue) were applied daily for 14d on each side of the ears. Scar samples were harvested at 2 wks, 4 wks, and 8 wks after the wounding. Each sample was stained with hematoxylin and eosin and the Masson's trichrome stain to evaluate inflammation and scar formation. Results: Histological analysis demonstrated a significant reduction of inflammation, neovascularization, and scar elevation in the experimental tissue as compared to the control. Additionally, experimental tissue exhibited faster improvement of collagen organization similar to that of normal tissue. Conclusion: This study suggests that the topical application of a selective COX-2 inhibitor on a rabbit ear wound resulted in decreased inflammation and had a positive effect on the reduction of scar formation.
This study was conducted to investigate the effects of slow-releasing fertilizer and sowing date on waxy corn propagated through double cropping without tillage. "Mibaek 2" was sown for first cropping on March 25th, April 5th, and April 15th, and for second cropping on July 5th, July 15th, and July 25th in 2018-2019. In order to save labor, slow-releasing fertilizer was utilized only one time before sowing. The accumulated temperature from sowing to silking was about 590-700℃. It took 65-77 days when "Mibaek 2" was sown in early April, but the one sown in early July took 42-52 days. In the first cropping, the culm length and ear length caused by the sowing date had no statistical significance, but the kernel set length was the highest at 123 cm in the sowing district on April 5th. The weight of marketable ears was the highest at 100%, in addition to soil testing-based recommended fertilization. Meanwhile, in the second cropping, culm length, ear length, and yield were less compared to the first cropping. The culm length, kernel set length, ear length, and seed set length decreased as sowing date was delayed. The number and yield of marketable ears were the highest at 100%, in addition to soil testing-based recommended fertilization like in the first cropping. It has been found that securing yield by July 15th to finish the second seeding of the crop in the central part of Korea is advantageous. These results of this study will be helpful to farmers for the double cropping of waxy corn cultivation and management.
Purpose : Hearing loss is one of the most common birth defects, and early detection and intervention positively impact language/speech and cognitive development. It has been reported that NICU graduates have a high incidence of hearing loss. So we investigated the incidence, risk factors and clinical outcome of hearing loss in NICU graduates. Methods : This study involved neonatal auditory brainstem response (ABR) testing of newborn infants who graduated from the NICU of Kyungpook National University Hospital during a 3-year period (between July 2002 and June 2005) and subsequent follow-up of these infants. Results : ABR evaluations were performed on 474 infants. Of these infants, 64 showed abnormal ABR (13.5 percent). Of 128 ears from these 64 infants, two ears (1.6 percent) and 10 ears (7.8 percent) were classified as severe and profound hearing loss, respectively. The infants with abnormal ABR had higher incidence of prematurity, low birth weight, very low birth weight, neonatal asphyxia, cranio-facial malformation and amikacin treatment over 15 days (P<0.05). In infants with hyperbilirubinemia, the peak level of serum bilirubin, duration of phototherapy and exchange transfusion were not associated with the higher incidence of hearing loss. Follow-up ABR evaluation was performed on 15 infants with abnormal ABR at $8.8{\pm}4.4months$. In follow-up ABR, 80.0% showed improvement or normalization of threshold sensitivity. Conclusion : NICU graduates exhibit high risk for hearing loss. Systemic and effective hearing assessment program is needed for these high risk infants.
Purpose : To examine the effect of unilateral otitis media and unilateral cerumen occlusion of the ear canal on thermometers. Methods : One hundred eighty six children with unilateral otitis media, fifty children with unilateral cerumen occlusion, and fifty children with neither otitis media nor cerumen were enrolled. Temperature was measured in both ear canals using thermometers. After 15 minutes, second temperature was measured again in both ears. Unilateral otitis media was graded by video otoscope for 7 grades. Differences in temperatures between affected ears and unaffected ears were analyzed. Results : No temperature difference between the normal and cerumen groups was observed. The mean temperature of the otitis media ear canal was $0.13{\pm}0.20^{\circ}C$ higher than that of the intact ear canal ($36.99{\pm}0.54^{\circ}C$ vs $36.86{\pm}0.52^{\circ}C$; P<0.001). There was no statistically significant temperature difference between grades. Conclusion : Unilateral otits media can affect estimation of body temperature measured by thermometers.
The Journal of the Convergence on Culture Technology
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v.7
no.1
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pp.570-575
/
2021
Since humans live while feeling rich in their five senses, care must be taken not to damage their hearing in order to lead a happy life. Hearing damage suffered in a living environment is common in a partial band where a specific frequency band is first damaged. However, since the initial pain of hearing damage does not appear much, it is difficult to determine the symptoms in the early stages. In this paper, we proposed a high-speed measurement method that can easily and quickly self-measure hearing damage through a simple app. In this method, 9 pure tones compensated for gain for each voice soub-band are alternately heard in both ears, so that one's own hearing damage can be detected at high speed. When 18 tone pulses were heard for 30 seconds per person, 1 out of 12 subjects was identified as suspected of partial hearing damage. And when the test subjects were informed of the hearing determination method for the number of hearings, the participants themselves immediately determined whether their hearing was damaged. This measurement method simply judges the hearing of both ears within 30 seconds with a smart phone, so that hearing measurements that took more than 10 minutes in hospitals are relatively accurate, and it was found that hearing health can be maintained while reducing time and costs.
The studies reported herein are on the varietal differences of rice in the effects of seeding times and nursery periods on the components such as, culm length, ear length, number of ears, ear weight, straw weight, and grain/straw ratio following the first series of studies on heading date. In the present investigations, 50 rice varieties, as the preceding studies, were seeded nine times at the interval of 15 days from March 15 to July 28 in 1963. Each variety seeded at respective time was transplanted in 40 days in nursery after seeded. Reviewing the result obtained from the first series of the studies on heading date, the number of days required to heading from seeding were decreased by delaying the seeding time. Most varieties tended to decrease in the number of days from seeding to heading by the 8th planting time. Some of varieties seemed to be decreased in the number of days from seeding to heading by 9th seeding time. However most varieties were failed to show heading delaying the seeding date at the 10th seeding. The results on the effects of altering the seeding time on the components and varietal differences of the response are summarized as follows; 1) Culm length; It appeared that culm length was shortened when the number of days from seeding to heading was decreased by delaying the seeding date. The varieties which needed many days to heading were also shortened in their culm length. 2) Ear length; Ear length was also shortened when the number of days needed tocheading was decreased, by delaying the seeding time. The varieties which needed many days for heading were also shortened in their ear length, while those which headed earlier seemed to be lengthened in their ear lengths. 3) Number of ears; It was shown that the number of ears was increased with the delay of the heading date, whereas, at the 9th seeding the number of ears was decreased when delayed the heading date. 4) Ear weight; Ear weight per hill was also likely to be heavy throughout the seeding times and varieties except the 7th and 8th seedings in which it appeared to be light on the contrary. 5) Straw weight; Straw weight became heavier as delayed the seeding date throughout all the varieties and seeding dates. 6) The grain/straw ratio; The grain/straw ratio was gradually increased by the 5th seeding time, reaching the pick at 5th. An examination of the varieties at each seeding date showed that the grain/straw ratio was low from 1st to 3rd seeding and from 7th to 9th seeding, when the number of days required to heading from seeding are increased. At the 4th seeding time-which is standard seeding time-5th, and 6th seeding times the ratio was high with the delay of heading.
This study investigated up-styling techniques as related to wedding dress image. To find up-styles that fit well with a wedding dress, a questionnaire survey was conducted targeting hairdressers in the beauty industry, and new styles were created and suggested based on the survey results. For this, hair was slicked back without parting and combed upward. Then, using braiding techniques needed to produce a top point, styles were created to create attractive images. For up-styles that go with an elegant wedding dress, hair was parted in a ratio of 3 : 7. In addition, a roll technique was applied based on natural points by keeping the ears half-covered to create elegance. For up-styles that are perfect for a classic wedding dress, hair was parted in a ratio of 2 : 8, keeping the ears half-covered. Based on the back point, a twisting technique was applied to create classic images. It is anticipated that the study results would provide basic data needed for creating and understanding up-styles that go with various wedding dress images and make a contribution to their development.
Woo, Taeyong;Kim, Young Seok;Roh, Tai Suk;Lew, Dae Hyun;Yun, In Sik
Archives of Plastic Surgery
/
v.43
no.6
/
pp.512-517
/
2016
Background Studies of the ear-molding technique have emphasized the importance of initiating molding early to achieve the best results. In the present study, we describe the immediate effects and long-term outcomes of this technique, focusing on children who were older than the ideal age of treatment initiation. Methods Patients who visited our institution from July 2014 to November 2015 were included. Medical charts were reviewed to collect data on demographics, the duration of treatment, the types of deformities, and the manner of recognition of the deformity and referral to our institution. Parents were surveyed to assess the degree of improvement, the level of procedural discomfort at the end of treatment, any changes in the shape of the molded auricle, and overall satisfaction 12 months after their last follow-up visits. Results A review of 28 ears in 18 patients was conducted, including the following types of deformities: constricted ear (64.2%), Stahl ear (21.4%), prominent ear (7.1%), and cryptotia (7.1%). The average score for the degree of improvement, rated on a 5-point scale (1, very poor; 5, excellent), was 3.5 at the end of treatment, with a score of 2.6 for procedural discomfort (1, very mild; 5, very severe). After 12 months, the shapes of all ears were well maintained. The average overall satisfaction score was 3.6 (1, very dissatisfied; 5, very satisfied). Conclusions We had reasonable outcomes in older patients. After 1 year of follow-up, these outcomes were well maintained. Patients past the ideal age at presentation can still be candidates for the molding technique.
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