• 제목/요약/키워드: EQ-Short-K

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운동, 알코올, 약물 등 복합적 요인으로 유발된 횡문근융해증 환자 치험 1례 (A Case Report of Rhabdomyolysis Induced by a Combination of Exercise, Alcohol, and Medication)

  • 진준수;이희정;민백기;공원호;서호석;김진원
    • 대한한방내과학회지
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    • 제39권5호
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    • pp.904-913
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    • 2018
  • Rhabdomyolysis is a syndrome that evokes either myopathy or cola-colored urine with elevated creatine kinase and myoglobin levels. The most common complication of rhabdomyolysis is acute renal failure (ARF). A large quantity of fluid must be injected promptly the first time symptoms appear, whereas sequela of symptoms has remained in the long run. In this report, a 58-year-woman was diagnosed with ARF due to rhabdomyolysis induced by exercise, alcohol, and medication. A treatment of acupuncture and herbal medicines was carried out for over 2 months. To evaluate the condition of the patient's lower limb, a short form of the McGill Pain Questionnaire, Visual Analogue Scale (VAS), European Quality of Life-5 Dimensions (EQ-5D), and Manual Muscle Test (MMT) points were used. As a result, clinical symptoms and quality of life improved noticeably after treatment with Korean medicine. This suggests that Korean medicine has an effect on rhabdomyolysis.

ICT센터 사례 연구를 통한 EQS의 건축 구조물 면진에의 적용 연구 (A Study on the Application of EQS bearings for the Seismic Isolation of Building Structures by ICT Case study)

  • 유성문;이유인;지용수;최대성;김두기
    • 한국지진공학회논문집
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    • 제17권2호
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    • pp.61-70
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    • 2013
  • An application of the EQS (Eradi Quake System) bearings to a short period building structure and the structure earthquake responses according to the design parameters of the EQS are studied by the ICT Center case study. The features of the EQS application to seismic isolated building structures are investigated, and the design procedure to determine the yield load and the secondary stiffness of the EQS is also studied. A computational analysis is performed to confirm the applicability of the EQS to the building structure and the earthquake responses according to the design parameters. The ICT Center in Indonesia is adopted as an application case of the EQS. The application of the EQS is found to extend the fundamental period of the ICT Center. Three types of EQS with different yield loads and secondary stiffness are designed and applied in the earthquake response analyses. The analysis results show the response of the structure with respect to the design parameters and which type of EQS is suitable for the ICT Center.

홀스타인 수소에 있어서 Chromium Picolinate의 첨가가 성장성적, 혈액성상 및 도체품질에 미치는 영향 (Effects of Chromium Picolinate on Growth Performance, Carcass Characteristics and Plasma Components in Holstein Bulls)

  • 홍중산;김명국;김윤학;한승은;이홍구;이현준;최윤재
    • Journal of Animal Science and Technology
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    • 제44권4호
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    • pp.419-426
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    • 2002
  • 본 시험은 성장단계별로 서로 다른 수준의 CrP를 첨가하여 성장성적, 혈액성상 및 도체품질에 미치는 영향을 규명하고자 실시하였다. 시험Ⅰ에서 일당증체, 일당건물섭취량 및 사료효율에는 유의적인 차이가 없었다(p>0.05). 혈액성상에서 혈장 Glucose와 PUN의 농도에는 영향이 없었지만 혈중 인슐린의 농도는 0.05% CrP첨가구가 대조구의 2배되는 1.47ng/ml 인데 반하여 혈중 NEFA의 농도는 59.00 mEq/dl 로 유의적으로 낮게 나타났다(p<0.05). 이는 인슐린의 농도의 증가 및 인슐린의 활성의 증가로 인하여 지방합성대사가 활발히 진행된 결과로 사료된다. 이러한 결과를 도체분석결과가 뒤받침 해주고 있는데 비록 통계적인 유의차는 없지만 0.05% CrP 첨가구의 등지방두께가 대조구에 비해 22.33% 높은 3.67cm로 나타났다. 시험Ⅱ에서 비록 일당증체, 일당건물섭취량 및 사료효율에는 유의적인 차이가 없었지만(p>0.05), 첨가초기 즉 0.05% CrP 첨가구에서는 첫 60일간, 0.025% CrP 첨가구에서는 첫 120일간 대조구보다 우수한 성적을 나타냈다. 혈장 Glucose와 PUN의 농도에는 영향이 없었다. 통계적인 유의차는 없었지만 혈 중 인슐린의 농도는 0.025% CrP 첨가구는 대조구보다 8.88% 높은 1.35ng/ml로 나타났고 0.05% CrP 첨가구는 오히려 1.13ng/ml로 대조구보다 낮게 나타났다. NEFA의 농도는 시험Ⅰ에서와 같은 차이는 없었지만 CrP 첨가수준이 증가할수록 감소하는 추세를 나타냈고 등지방두께는 일정한 변화추세를 보이지 않았다.

일부 저염식 피교육자의 식염섭취 및 뇨중 Sodium 배설양상 -장류 및 김치류 등 고식염 함유 식품을 중심으로- (A Study on Salt Intake and Urinary Sodium Excretion by Groups Educated Regarding Low Salt Diet)

  • 김기순;신동천;이숙재;김혜경
    • Journal of Nutrition and Health
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    • 제13권4호
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    • pp.187-194
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    • 1980
  • To estimate the amount of daily salt intake by source of food and urinary sodium excretion, a dietary survey was conducted from August 27th to September 3, 1980. The salt concentration of six kinds of food was measured. The families of 25 womens' club leaders and 25 families of hypertensive patients were studied after they had been given a short course of education on lowsalt diet. The results were as follows: 1. The average amount of high-salt foods eaten daily by the study group were as follows: 4.5 Gm. in the form of table salt 16.8 ml of home-made soy sauce 6.20 ml of commercial soy sauce 11.9 Gm. of home-made red-pepper bean paste 12.0 Gm. of home-made soy-bean paste 120.7 Gm. of Kimchi 2. The average NaCl concentration of each food was as follows: 99.5% in table salt, 22.5% in home made soy sauce, 11.9% in Commercial soy sauce, 6.8 Gm% in home made red pepper bean paste, 9.2 Gm% in home-made soy-bean paste and the average concentration of various kinds of Kimchi was 2.7 Gm%. 3. The total amount of daily salt intake per adult was calculated as 14.3 Gm. By sources of food 4.5 Gm from table salt, 3.9 Gm from home-made soy sauce and 3. 3 Gm from Kimchi were taken daily Three other kinds of food were also minor sources of salt intake.4. The average amounts of individual daily salt intake were not significantly different between the hypertensive group and the normotensive group: the median of the normotensive group (11.7Gm.) was significantly lower than that of the hypertensive group (14.9Gm.). Therefore the womens' club leaders appeared to respond more quickly than the hypertensive group after low-salt diet education. 5. The average amount of sodium excretion in the 24 hour urine specimen was 234.7 mEq. From this finding the daily NaCl intake was estimated to be 15.8Gm.

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영남권역에서 가정용 인공호흡기를 사용하는 환자 가족간병인의 간병 부담과 삶의 질 (Survey on the Care Burden and Quality of Life in Family Caregivers of Patients Using Home Mechanical Ventilator in Yeongnam Region, Korea)

  • 손주현;문명훈;조미경;윤라유;허성철;민지홍;문정인;김수연
    • 대한지역사회작업치료학회지
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    • 제10권1호
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    • pp.39-49
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    • 2020
  • 목적 : 본 연구는 영남권역 내 가정에서 인공호흡기 사용 환자를 돌보는 가족간병인이 느끼는 간병 부담과 삶의 질을 알아보고자 하였다. 연구방법 : 영남권역 내에 거주하며 가정에서 인공호흡기를 사용하는 환자를 돌보는 주간병인을 대상으로 설문조사를 시행하였고 가족간병인의 응답 내용을 분석하였다. 설문지는 환자의 정보, 간병 실태 및 추가 지원 요구 사항 등으로 구성하였다. 가족간병인의 간병 부담과 삶의 질을 평가하기 위해 각각 Korean version of Short Form Zarit Burden Interview(K-ZBI-12)과 한국형 가중치 모형에 따라 교정한 3-Level version of EuroQol-5 Dimension(KEQ-5D-3L)을 사용하였다. 통계적 유의수준은 p<0.05로 하였다. 결과 : 총 150명 중 주간병인이 가족간병인인 98명을 분석하였다. 환자의 연령은 54.10±17.94세, 성별은 남자 74명(75.5%), 여자 24명(24.5%)이었고 주 진단은 신경근육계 질환이 83명(84.7%)으로 가장 많았다. 가족간병인의 K-ZBI-12 점수는 33.08±10.34로 간병에 대한 고부담을 보였고 EQ-5D-3L 점수는 0.71±0.25로 두 항목은 음의 상관관계를 보였다(p=.038). 환자의 연령, 인공호흡기 사용기간, 의료비에 대한 가족간병인의 경제적 부담, 간병비에 대한 가족간병인의 경제적 부담 및 전문간병인의 참여 시간은 K-ZBI-12 점수와 각각 통계적으로 유의한 상관관계를 보였다. KEQ-5D-3L 점수는 가정용 인공호흡기의 사용기간과 음의 상관관계를 나타냈다(p=.017). 환자가 침습적 인공호흡기를 사용하는 경우 비침습적 인공호흡기를 사용하는 경우보다 가족간병인의 KEQ-5D-3L 점수가 낮았다(p=.008). 간병에 참여하는 인원이 두 명 이상인 경우가 한 명인 경우보다 K-ZBI-12 점수가 낮았다(p=.001). 가족간병인이 추가지원을 바라는 요구사항 중 경제적 지원에 대한 요구도가 가장 높게 조사되었다. 결론 : 영남권역에서 가정용 인공호흡기를 사용하는 환자들의 보호자가 느끼는 간병 부담이 크고 삶의 질이 낮다는 것을 알 수 있다. 가족간병인의 간병 부담과 삶의 질을 개선하기 위해서 지역에서 실질적으로 필요한 사회경제적 지원 및 환자와 가족들의 요구 사항을 확인하고 추가적인 지원을 위한 노력이 필요하다.

Glass Dissolution Rates From MCC-1 and Flow-Through Tests

  • Jeong, Seung-Young
    • 한국방사성폐기물학회:학술대회논문집
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    • 한국방사성폐기물학회 2004년도 학술논문집
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    • pp.257-258
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    • 2004
  • The dose from radionuclides released from high-level radioactive waste (HLW) glasses as they corrode must be taken into account when assessing the performance of a disposal system. In the performance assessment (PA) calculations conducted for the proposed Yucca Mountain, Nevada, disposal system, the release of radionuclides is conservatively assumed to occur at the same rate the glass matrix dissolves. A simple model was developed to calculate the glass dissolution rate of HLW glasses in these PA calculations [1]. For the PA calculations that were conducted for Site Recommendation, it was necessary to identify ranges of parameter values that bounded the dissolution rates of the wide range of HLW glass compositions that will be disposed. The values and ranges of the model parameters for the pH and temperature dependencies were extracted from the results of SPFT, static leach tests, and Soxhlet tests available in the literature. Static leach tests were conducted with a range of glass compositions to measure values for the glass composition parameter. The glass dissolution rate depends on temperature, pH, and the compositions of the glass and solution, The dissolution rate is calculated using Eq. 1: $rate{\;}={\;}k_{o}10^{(ph){\eta})}{\cdot}e^{(-Ea/RT)}{\cdot}(1-Q/K){\;}+{\;}k_{long}$ where $k_{0},\;{\eta}$ and Eaare the parameters for glass composition, pH, $\eta$ and temperature dependence, respectively, and R is the gas constant. The term (1-Q/K) is the affinity term, where Q is the ion activity product of the solution and K is the pseudo-equilibrium constant for the glass. Values of the parameters $k_{0},\;{\eta}\;and\;E_{a}$ are the parameters for glass composition, pH, and temperature dependence, respectively, and R is the gas constant. The term (1-Q/C) is the affinity term, where Q is the ion activity product of the solution and K is the pseudo-equilibrium constant for the glass. Values of the parameters $k_0$, and Ea are determined under test conditions where the value of Q is maintained near zero, so that the value of the affinity term remains near 1. The dissolution rate under conditions in which the value of the affinity term is near 1 is referred to as the forward rate. This is the highest dissolution rate that can occur at a particular pH and temperature. The value of the parameter K is determined from experiments in which the value of the ion activity product approaches the value of K. This results in a decrease in the value of the affinity term and the dissolution rate. The highly dilute solutions required to measure the forward rate and extract values for $k_0$, $\eta$, and Ea can be maintained by conducting dynamic tests in which the test solution is removed from the reaction cell and replaced with fresh solution. In the single-pass flow-through (PFT) test method, this is done by continuously pumping the test solution through the reaction cell. Alternatively, static tests can be conducted with sufficient solution volume that the solution concentrations of dissolved glass components do not increase significantly during the test. Both the SPFT and static tests can ve conducted for a wide range of pH values and temperatures. Both static and SPFt tests have short-comings. the SPFT test requires analysis of several solutions (typically 6-10) at each of several flow rates to determine the glass dissolution rate at each pH and temperature. As will be shown, the rate measured in an SPFt test depends on the solution flow rate. The solutions in static tests will eventually become concentrated enough to affect the dissolution rate. In both the SPFt and static test methods. a compromise is required between the need to minimize the effects of dissolved components on the dissolution rate and the need to attain solution concentrations that are high enough to analyze. In the paper, we compare the results of static leach tests and SPFT tests conducted with simple 5-component glass to confirm the equivalence of SPFT tests and static tests conducted with pH buffer solutions. Tests were conducted over the range pH values that are most relevant for waste glass disssolution in a disposal system. The glass and temperature used in the tests were selected to allow direct comparison with SPFT tests conducted previously. The ability to measure parameter values with more than one test method and an understanding of how the rate measured in each test is affected by various test parameters provides added confidence to the measured values. The dissolution rate of a simple 5-component glass was measured at pH values of 6.2, 8.3, and 9.6 and $70^{\circ}C$ using static tests and single-pass flow-through (SPFT) tests. Similar rates were measured with the two methods. However, the measured rates are about 10X higher than the rates measured previously for a glass having the same composition using an SPFT test method. Differences are attributed to effects of the solution flow rate on the glass dissolution reate and how the specific surface area of crushed glass is estimated. This comparison indicates the need to standardize the SPFT test procedure.

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