• Title/Summary/Keyword: EMULSION

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Release Profile of Peptide from Biodegradable Microspheres: Comparison of Blending and Multiple Emulsion Method (고분자 혼합법과 다중 에멀젼법에 의해 제조된 생분해성 미립구로부터 펩타이드의 용출에 관한 연구)

  • Jung, Goo-Young;Kim, Jung-Kwoun;Park, Mork-Soon;Myung, Pyung-Keun
    • Journal of Pharmaceutical Investigation
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    • v.36 no.4
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    • pp.245-251
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    • 2006
  • The novel microsphere blending and multiple emulsion method by single process was tried to prepare sustained release microspheres which release a physiologically active substance for long periods of time. A drug was separately dissolved in each of two or more oils containing biodegradable polymers to give the primary oil phases. The primary oil phases were dispersed in single aqueous phase in succession. From the drug-dispersed solution, the organic solvent was removed to produce microspheres. The accelerated drug release from the microsphere formulation prepared by single process through the multiple emulsion method was very similar to a physical blending of separately prepared microspheres using the same polymers. But long term release was not same. In this study, leuprorelin acetate loaded poly(lactide-co-glycolide) microsphere formulation for one-month delivery was developed by the multi-emulsion method followed by solvent extraction/evaporation method.

A Study on the Stabilization of Asphalt Emulsion with Phase Inversion Emulsification Method (반전유화법에 의한 유화아스팔트의 안정성 연구)

  • Heo, Woo-Sung;Lee, Eun-Kyoung;Choi, Sei-Young
    • Elastomers and Composites
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    • v.44 no.2
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    • pp.143-149
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    • 2009
  • In this study, asphalt emulsion was manufactured by phase inversion emulsification method with nonionic surfactants(Span 80, Span 60, Tween 80, and Tween 60), anionic surfactant(SLS) and cationic surfactant(Imidazole) in different feeding ratio to make up for the week points of asphalt. Its stabilization was carefully investigated with respect to droplet size, viscosity, zeta potential, and water-proofing property. When the surfactants mixed with nonionic and anionic surfactant were used into the asphalt, a stabilization of the asphalt emulsion was good. As the amount of the mixed surfactant was increased, the droplet size of asphalt emulsion were decreased, while the viscosity and zeta potential were increased. When the surfactants mixed with nonionic and anionic surfactant were used into the asphalt, a stabilization of asphalt emulsion was good.

Effects of Partial Beef Fat Replacement with Gelled Emulsion on Functional and Quality Properties of Model System Meat Emulsions

  • Serdaroglu, Meltem;Nacak, Berker;Karabiyikoglu, Merve;Keser, Gokcen
    • Food Science of Animal Resources
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    • v.36 no.6
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    • pp.744-751
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    • 2016
  • The objective of this study was to investigate the effects of partial beef fat replacement (0, 30, 50, 100%) with gelled emulsion (GE) prepared with olive oil on functional and quality properties of model system meat emulsion (MSME). GE consisted of inulin and gelatin as gelling agent and characteristics of gelled and model system meat emulsions were investigated. GE showed good initial stability against centrifugation forces and thermal stability at different temperatures. GE addition decreased the pH with respect to increase in GE concentration. Addition of GE increased lightness and yellowness but reduced redness compared to control samples. The results of the study showed that partial replacement of beef fat with GE could be used for improving cooking yield without negative effects on water holding capacity and emulsion stability compared to C samples when replacement level is up to 50%. The presence of GE significantly affected textural behaviors of samples (p<0.05). In conclusion, our study showed that GE have promising impacts on developing healthier meat product formulations besides improving technological characteristics.

De-emulsification of Petroleum Emulsion Using Nocardia amarae (Nocardia amarae를 이용한 석유 유상액의 탈유화)

  • Lee, Ki-Young;Lee, Jin-Jong;Kim, Dong-Won;Na, Kun;Lee, Jae-Chan
    • KSBB Journal
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    • v.13 no.2
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    • pp.209-213
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    • 1998
  • The characteristics of de-emulsification of pertroleum emulsion by Nocardia amarae were investigated. Insoluble medium containing n-hexadecane was more effective than soluble medium in de-emulsification of emulsion containing diesel and bunker C as the organic phase. Emulsion made by the addition of xanthan or bioemulsifier was de-emulsified by N. amarae, and longer culture age was effective. In low viscosity range, organic phase with longer carbon chain was more effective. The contact, angle between bacterial film and water droplet in air increased from 16 degree for 4 day culture age to 26 degree for 15 day. The contact angle between bacterial film and water droplet in kerosene, n-heyxane or n-hexadecane also increased to greater than 100 degree after 3 day culture age. The hydrophobicity of bactgerial film increased according to the culture age.

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Emulsion Polymerization of Co-polymers Having Both Hydrophilic and Hydrophobic Side Chains and Their Adhesion Properties

  • Takahashi, S.;Shibamiya, N.;Kasemura, T.
    • Journal of Adhesion and Interface
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    • v.3 no.1
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    • pp.13-19
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    • 2002
  • We have studied on the surface and adhesion properties for acrylic terpolymers, having both hydrophobic and hydrophilic side chains, synthesized via solution polymerization. In order to develop a waterborne material. we tried to synthesize these terpolymers via emulsion polymerization. The polymeric emulsion synthesized was mainly composed of methyl methacrylate (MMA), methoxy-polyethyleneglycol methacrylate (MPEGMA) having hydrophilic side chains and methoxypolypropyleneglycol methacrylate (MPEGMA) having hydrophobic side chains. The viscosities of this series increased with an increase in the content of the co-monomer such as MPEGMA and (MPEGMA). This behavior resulted in the increase in the diameter and heterogeneity of the emulsion particle via AFM observation. Furthermore. the tensile adhesion strength and 90-degree peel strength of the adhesive of these polymeric emulsions were measured. In the case of polymeric emulsion composed of the same content of both hydrophilic and hydrophobic component, the adhesion property showed the highest value. However, since the adhesion properties as a practical applicable adhesive were poor, some improvements were required. When the composition above was modified with butyl acrylate (BA), the improvement effect on adhesion strength was accepted. In particular, 90-degree peel strength increased up to a maximum of 400% of the original value.

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Lipids Supply for Hybridoma Culture (하이브리도마 배양을 위한 lipids의 공급)

  • 박상재;최차용
    • KSBB Journal
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    • v.8 no.5
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    • pp.483-487
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    • 1993
  • BSA/acids component in serum free medium (SFM) developed for the culture of hybridoma cell line, KA112, was replaced by acids/Pluronic F-68 emulsion. Protein content of SFM was minimized, and increased maximum cell density was obtained in serum-free lipids supplemented medium (SFLSM). Cell growth promotion effect of the emulsion was not affected by filtration with 0.2$\mu$m filter.

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EVAc emulsion에 의한 Cement 미세구조의 변화

  • 김창은
    • Cement Symposium
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    • no.17
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    • pp.15-21
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    • 1989
  • 시멘트 모르타르에 EVAc 에멀젼 및 계면활성제(Sodium Dodecylbenzenesulfonate)를 첨가하여 압축강도, 흡수율, 화학적 저항성, 수화발열속도, 전자현미경 등으로 그 물성을 관찰하였다. EVAc를 시멘트에 첨가할 경우 5-15wt$\%$, SDBF는 0.03wt$\%$를 첨가하고 혼수량을 flow value로써 기준하는 것이 최적조검임을 알 수 있었다. 그리고 EVAc emulsion을 첨가함으로써 혼수량 및 흡수율의 감소 효과를 거둘 수가 있었으며 또한 화학적 저항성도 증가되었다. EVAc emulsion을 과다 첨가할 경우에는 기포가 많이 형성되어 강도가 저하하나, 여기에 계면활성제(Sodium Dodecylbenzenesulfonate)를 가하면 강도가 증가하였으며, 한편 수화 속도는 지연되었다.

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Combustion Characteristics of Heavy Fuel Oil-water Emulsion

  • Kim Houng-Soo
    • Journal of Advanced Marine Engineering and Technology
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    • v.30 no.1
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    • pp.88-92
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    • 2006
  • This study is intended to check the flame temperature to raise in burning grade C heavy fuel oil and emulsion fuel oil in a boiler and to measure the concentration of Dry Shoot(DS) and Soluble Organic Fraction(SOF) after collecting the Particulate Matters (PM). The flames temperature in boiler was measured by burning grade C heavy oil and oil-water emulsion (C heavy oil $70\%\;and\;30\%$ of water) Combustion characteristics of two fuels was also compared by trapping particulate matters (PM) in exhaust gas and measuring the generated quantities of DS and SOF in fuel gas.

A Study on Spray Characteristics of Diesel-Water Emulsion with Ultra High Pressure (초고압 경유-물 혼합연료의 분무특성에 관한 연구)

  • Jeong, D.Y.;Lee, J.T.
    • Journal of ILASS-Korea
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    • v.8 no.1
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    • pp.29-36
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    • 2003
  • Spray characteristics on diesel- water emulsion are analyzed in high pressure injection for several variables such as water content, injection pressure. Spray Patterns were visualized under various water content and injection pressures. Spray tip penetration was increased and spray angle decreased in accordance with increasing of water content. But these characteristics were enhanced with increase of injection pressure to high pressure.

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A Stability on the Solvents of Spectral Sensitizer for Photographic Emulsion (사진유제용 분광증감색소의 용매에 대한 안정성)

  • Kim, Yeoung-Chan
    • Journal of the Korean Applied Science and Technology
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    • v.14 no.2
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    • pp.65-70
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    • 1997
  • The symmetric naphthothiazolo carbocyanine is of industrial importance as red-sensitizing dye in the spectral sensitization of emulsion microcrystals in negative film-making. The stability on the solvents of naphthothiazolo carbocyanine dye was measured by UV-Vis spectrophotometer, and then all of solvents were stabilized sensitizer. The maximum absorption peak range in various solvents was $600nm{\sim}612nm$. But it was identified that only methanol can be used to photographic emulsion.