• ETRI Journal
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• 제9권2호
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• pp.96-105
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• 1987

1.544Mb/s 속도의 D3/PCM 신호를 수신할때 프레임 동기를 위한 확률적인 방법으로 BER 조건 및 es, em에 의한 동기회로의 성능을 계산하였으며, 이론적인 분석이 가능한 실제 하드웨어로 실현하였다. 실현된 회로에 의하면 전송로의 BER이 최악인 $10^-2$이고 es=0, em=2인 경우, 초기 탐색시간, 동기 유지시간, 재동기 시간은 각각 2.87ms, 9.9시간, 2.69ms가 된다. 또한 실제 전송로의 환경 조건에 따라 쉽게 하드웨어를 변경할 수 있을 뿐만 아니라 1.544Mb/s 속도를 새로운 신호형태에도 간단히 개조하여 적용할 수 있다.

• Advances in Traditional Medicine
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• 제7권4호
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• pp.357-362
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• 2007

Cytochrome P450 2C19 (CYP2C19) is a clinically important enzyme involved in the metabolism of therapeutic drugs, including (S)-mephenytoin, omeprazole, proguanil, and diazepam. Individuals are characterized as either extensive metabolizers (EM) or poor metabolizers (PM) on the basis of CYP2C19 enzyme activity. The PM phenotype occurs in 2-5% of Caucasians, but in 18-23% of Asians. To clarify the association between CYP2C19 polymorphisms and gastric cancer in Koreans, we investigated CYP2C19 genotypes ($CYP2C19^*1,\;{^*2},\;and\;^*3$) in 109 patients with gastric cancer and 211 controls. Normal ($CYP2C19^*1$) and defective alleles were detected with polymerase chain reaction/restriction enzyme analysis. CYP2C19 has three hereditary genotypes: homozygous EM, with high enzymatic activity; heterozygous EM, with moderate enzymatic activity; and PM, with no enzyme activity. We found that CYP2C19 heterozygous EM is more closely associated with gastric cancer than is homozygous EM. Because the CYP2C19 genotype varies in Koreans, a genotyping test is desirable to prevent gastropathy recurrence in patients before their doses of omeprazole are reduced during maintenance therapy.

• 한국수산과학회지
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• 제51권4호
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• pp.397-403
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• 2018

We determined the resistance rates of pathogenic bacteria isolated from cultured olive flounder Paralichthys olivaceus to erythromycin (Em), antibiotic typically used in aquaculture and analyzed the genotypes of resistant bacteria using polymerase chain reaction (PCR). We isolated and utilized 160 isolates of Streptococcus parauberis, 1 of S. iniae, 66 of Edwardsiella tarda, 56 of Vibrio sp. and 23 of unidentified bacteria from presumed infected olive flounder from Jeju Island from March 2016 to October 2017. Of the 306 isolated strains, Em-resistant strains included 33 of S. parauberis, 39 of E. tarda and 2 of Vibrio sp. We conducted PCR to assess the resistance determination of Em-resistant strains. Five different types of Em-resistance genes were detected in the 74 Em-resistant strains: erm (A), erm (B), erm (C), mef (A) and mef (E); erm (A) and erm (B) were detected in 1 (3%) and 24 (72.7%) S. parauberis isolates, respectively. In E. tarda, erm (B) was detected in five isolates (12.8 %) and no Em-resistance genes were detected in the two Vibrio sp. isolates.

• Journal of Veterinary Science
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• 제23권2호
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• pp.30.1-30.6
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• 2022

This report aims to describe the first case of muscular and collagenous choristoma in a dog. A 10-yr-old female mixed-breed dog presented with lateral recumbence, vocalization, positional vertical nystagmus, divergent strabismus, anisocoria, and status epilepticus. The clinical condition evolved to stupor and ultimately, death. Necropsy revealed a white mass causing an irregular increase in the volume of the cerebellar vermis. In histological analysis, a well circumscribed, unencapsulated mass was observed in the cerebellum, consisting of fibers of striated skeletal muscle and collagen fibers, mostly mineralized. Based on the histopathological and histochemical findings, a diagnosis of muscular and collagenous cerebellar choristoma was made.

• Journal of electromagnetic engineering and science
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• 제8권2호
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• pp.70-75
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• 2008

In this paper, the EM wave absorber was designed and fabricated for countermeasure against EMI from a ceiling of a tollgate in ETC system. We fabricated several samples in different composition ratios of MnZn-ferrite, Carbon, and CPE(Chlorinated Polyethylene). Absorption abilities were simulated in accordance with different thicknesses of the prepared absorbers and changed complex relative permittivity and permeability according to composition ratio. The optimized mixing ratio of MnZn-ferrite, Carbon, and CPE was found as 40:15:45 wt.% by experiments and simulation. Then the EM wave absorber was fabricated and tested using the simulated data. As a result, the developed EM wave absorber has the thickness of 3.3 mm and absorption ability was more than 20 dB in the case of normal incidence and more than 11 dB for the incident angle from 15 to 45 degrees at 5.8 GHz. Therefore, it was confirmed that the newly developed absorber can be used for ETC system.

• 한국항해항만학회지
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• 제28권6호
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• pp.503-507
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• 2004

폐 처리된 스토론튬(Sr) 페라이트를 사용하여 GHz 대역용 전파흡수체를 개발하였다. 도전손실재인 카본의 첨가에 따른 전파흡수능의 변화와 시편 제작시 제작온도 변화에 따른 전파흡수능의 변화를 조사하였다. 이와 같은 실험을 실시하여 스토론튬(Sr) 페라이트 : 실리콘 (slicone)고무 : 카본 (carbon)=80 : 13.6 : 6.4 wt%인 시편을 7$0^{\circ}C$에서 제작하여 두께 2mm인 시편에 대하여 9.4 GHz에서 -24 dB, 두께 3mm인 시편에 대하여 5.5 GHz에서 -23 dB인 우수한 전파흡수체를 개발하였다.

• Journal of electromagnetic engineering and science
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• 제2권1호
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• pp.16-21
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• 2002

On the contrary to the progress of the electronic industry and radio communication technologies, many social problems such as EMI, due to unnecessary electromagnetic(EM) wave are serious with the increased use of EM wave. It is required that the absorbing capability of an EM wave absorber is more than 20 dB, the bandwidth of which is required from 30 MHz to 18 GHz to satisfy the international standard about an anechoic chamber for EMI/EMS measurement$^{[1]}$TEX>. However, the absorbing frequency band of the conventional EM wave absorbers satisfying more than 20 dB is very narrow, for examples, from 30 MHz to 400 MHz in ferrite tile type and from 30 MHz to 870 MHz in ferrite grid type, respectively. In this paper, we proposed and designed a new tripe absorber with broadband characteristics covering the frequency band from 30 MHz to 10 GHz by use of the equivalent material constants method (EMCM)$^{[2]~[4]}$TEX>.

• Journal of Trauma and Injury
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• 제20권2호
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• pp.130-137
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• 2007

Purpose: Ultrasound is of proven accuracy in abdominal and thoracic trauma and may be useful for diagnosing extremity injury in situations where radiography is not available, such as disasters and military and space applications. However, the diagnosis of fractures is suggested by history and physical examination and is typically confirmed with radiography. As a alternative to radiography, we prospectively evaluated the utility of extremity ultrasound performed by trained residents of emergency medicine (EM) one patient with wrist and ankle extremity injuries. Methods: Initially, residents of EM performed physical examinations for fractures. The emergency ultrasound (EM US) was performed by trained residents, who used a portable ultrasound device with a 10- to 5-MHz linear transducer, on suspected patients before radiography examination. The results of emergency ultrasound and radiography and the final diagnosis were recorded, and correlation among them were determined by using Kappa s test Results: Thirty-nine patients were enrolled in our study. The average age was $36.6\;{\pm}\;19.3$ years. There were radius Fx. (n=21), radius-ulna Fx. (n=1), ulna Fx. (n=1), and contusion (n=2) injuries among the wrist injury and lat.-med. malleolar Fx. (n=13), lat. malleolar Fx. (n=6), and med. malleolar Fx. (n=3) injuries among the ankle injury. Comparing EM US with radiography, we found the sensitivity, specificity, positive predictive value, and negative predictive value of EM US for Fx. diagnosis to be 100%, 66.7%, 97.3%, 100% and those of radiography to be 97.2%, 100%, 100%, and 75%, respectively. Kappa s test for a correlation between the Fx. diagnosis of EM US and the final diagnosis of Fx was performed, and Kappa's value was 0.787 (P = 0.004).Conclusion: EM US for Fx. can be performed quickly and accurately by EM residents with excellent accuracy in remote locations such as disaster areas and in military and aerospace applications. EM US was as useful as radiography in our study and had a high correlation to the final diagnosis of Fx. Therefore, ultrasound should performed on patients with extremity injury to determine whether extremity evaluation should be added to the FAST (focused abdominal sonography trauma) examination.

• 한국통신학회논문지
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• 제39A권3호
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• pp.127-139
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• 2014

멀티 레벨 낸드 플래시 메모리는 한 셀에 2 비트 이상의 정보를 저장하는 구조이고, 비트 위치별 채널 LLR의 밀도 함수 l-밀도가 비대칭 특성을 가지고 있다. 이런 특성은 이진 무기억 대칭 채널 조건에서 설계된 오류 정정부호의 성능이 제대로 발휘되지 못하게 할 뿐만 아니라, 멀티 레벨 낸드 플래시 메모리용 연판정 복호를 수행하는 이진 오류 정정 부호의 설계도 어렵게 한다. 본 논문에서 밀도 미러링과 EM 알고리즘을 이용하여 오류 정정 부호 설계를 위한 차선책을 소개한다. 밀도 미러링은 EM 알고리즘을 적용하기 전에 0 부호어를 전송한 경우로 가정할 수 있도록 하기 위해서 채널 LLR을 처리하는 과정이고, 이후 채널 LLR l-밀도를 EM 알고리즘을 적용하여 K개의 성분으로 이루어진 대칭 가우시안 혼합 밀도로 근사화하는 방법을 소개한다.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 2002년도 학술대회지
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• pp.317-334
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• 2002

Ginsenosides are metabolized (deglycosylated) by intestinal bacteria to active forms after oral administration. 20(S)-Protopanaxadiol $20-O-{\beta}-D-glucopyranoside$ (M1) and 20(S)-protopanaxatriol (M4) are the main intestinal bacterial metabolites (IBMs) of protopanaxadiol- and protopanaxatriol-type glycosides. M1 was selectively accumulated into the liver soon after its intravenous (i.v.) administration to mice, and mostly excreted as bile; however, some M1 was transformed to fatty acid ester (EMl) in the liver. EM1 was isolated from rats in a recovery dose of approximately $24mol\%.$ Structural analysis indicated that EM1 comprised a family of fatty acid mono-esters of M1. Because EM1 was not excreted as bile as Ml was, it was accumulated in the liver longer than M1. The in vitro cytotoxicity of M1 was attenuated by fatty acid esterification, implying that esterification is a detoxification reaction. However, esterified M1 (EM1) inhibited the growth of B16 melanoma more than Ml in vivo. The in vivo antitumor activity paralleled with the pharmacokinetic behavior. In the case of M4, orally administered M4 was absorbed from the small intestine into the mesenteric lymphatics followed by the rapid esterification of M4 with fatty acids and its spreading to other organs in the body and excretion as bile. The administration of M4 prior to tumor injection abrogated the enhanced lung metastasis in the mice pretreated with 2-chloroadenosine more effectively than in those pretreated with anti-asialo GMl. Both EM1 and EM4 did not directly affect tumor growth in vitro, whereas EM1 promoted tumor cell lysis by lymphocytes, particularly non-adherent splenocytes, and EM4 stimulated splenic NK cells to become cytotoxic to tumor cells. Thus, the esterification of IBM with fatty acids potentiated the antitumor activity of parental IBM through delay of the clearance and through immunostimulation. These results suggest that the fatty acid conjugates of IBMs may be the real active principles of ginsenosides in the body.