• Title/Summary/Keyword: ELF

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The Effects of Transformation Leadership and transactional leadership on Organizational Performance: Moderating Roles of Self-efficacy and Job Satisfaction (변혁적 리더십과 거래적 리더십이 조직성과에 미치는 영향 : 자기효능감과 직무만족의 매개효과를 중심으로)

  • Kwon, Hyeok-Gi
    • Management & Information Systems Review
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    • v.31 no.2
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    • pp.1-20
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    • 2012
  • The purpose of this study was to investigate the influence of leadership types and self-efficacy, job satisfaction on organizational performance. The hypotheses were suggested and data analyses were performed to verify these hypotheses. Data gathering were performed by self-administered questionnaires on the samples of 423 mechanical fields employees in Busan & kyongnam. The results of structural model exhibit that transformational leadership, transactional leadership was positively related to elf-efficacy. And it was also found that self-efficacy, job satisfaction was positively related to organizational performance. Expecially, it showed self-efficacy, job satisfaction as a mediator on the relationships between the leadership types and organizational performance.

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Epigenetic modification of retinoic acid-treated human embryonic stem cells

  • Cheong, Hyun-Sub;Lee, Han-Chul;Park, Byung-Lae;Kim, Hye-Min;Jang, Mi-Jin;Han, Yong-Mahn;Kim, Seun-Young;Kim, Yong-Sung;Shin, Hyoung-Doo
    • BMB Reports
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    • v.43 no.12
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    • pp.830-835
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    • 2010
  • Epigenetic modification of the genome through DNA methylation is the key to maintaining the differentiated state of human embryonic stem cells (hESCs), and it must be reset during differentiation by retinoic acid (RA) treatment. A genome-wide methylation/gene expression assay was performed in order to identify epigenetic modifications of RA-treated hESCs. Between undifferentiated and RA-treated hESCs, 166 differentially methylated CpG sites and 2,013 differentially expressed genes were discovered. Combined analysis of methylation and expression data revealed that 19 genes (STAP2, VAMP8, C10orf26, WFIKKN1, ELF3, C1QTNF6, C10orf10, MRGPRF, ARSE, LSAMP, CENTD3, LDB2, POU5F1, GSPT2, THY1, ZNF574, MSX1, SCMH1, and RARB) were highly correlated with each other. The results provided in this study will facilitate future investigations into the interplay between DNA methylation and gene expression through further functional and biological studies.

The Study on the Development of Self Efficacy Expectation Promoting Program and It's Effect for Breast Self Examination (유방자가검진을 위한 효능기대 증진 프로그램의 개발 및 효과)

  • Jung, Myung-Ok;Tae, Young-Sook
    • Asian Oncology Nursing
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    • v.2 no.1
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    • pp.50-60
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    • 2002
  • Breast self-exam is easiest, safe and cost effective to be recommended as an important method for early detection of breast cancer. This experimental research with non-equal control design was to develop the efficacy expectation program for breast self-exam based on Bandura's self-efficacy information source. The study objects selected from two local churches in Busan. Twenty from S church were selected as a study group, twenty from D church as a control group. Efficacy expectation promoting program was based on Bandura's efficacy promoting source and was two hour lecture including slide, video tape, demonstration, pamphlet. After this, there were individual interviews with them and consultations through telephone f or verbal persuasion on the weekly basis between the first week and the fifth week. The effect from the experiment were measured on the first week after education and on the fifth week. Data from control group was collected during the period from Jan 11, 2 001 to Feb 15, 2001 and data from study group was collected during the period from Jan 12, 2001 to Feb 16, 2001. Measurement instrument for this study was developed by the author with the advice of specialist in order to measure self-efficacy and breast self-exam practice. Data analysis was done by using SPSS/10.0 PC program $with^2-$ test. t-test and ANCOVA. Proved results for hypothesis were as follows. 1) It was supported that "Study group educated by efficacy expectation promoting program has higher score in change rat e of self-efficacy than control group." (1 week after education F=18.395, p=.000 5 weeks after education F=28.972, p=.000) 2) It was supported that "Study group educated by efficacy expectation promoting program has higher score in change rate of exam practice than control group." (1 week after education F=37.984, p=.000 5 weeks after education F=28.972, p=.000) In conclusion, efficacy expectation promoting program for breast self-exam developed by this study may increase s elf-efficacy and breast self-exam practice.

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Influence of 5′-(N′-Ethylcarboxanlido) Adenosine on Catecholarnine Secretion Evoked by Cholinergic Stimulation and Membrane Depolarization in the Rat Adrenal Gland

  • Lim, Dong-Yoon;Oh, Hyeong-Geun;Woo, Seong-Chang
    • Biomolecules & Therapeutics
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    • v.8 no.4
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    • pp.338-348
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    • 2000
  • The present study was attempted to determine the effect of 5'-(N'-ethylcarboxamido) adenosine (NECA), which is an potent $A_2$-adenosine receptor agonist, on catecholamine (CA) secretion evoked by cholinergic stimulation, membrane depolarization and calcium mobilization from the isolated perfused rat adrenal gland. NECA (20 nM) perfused into the adrenal vein for 60 min produced a time-related inhibition in CA secretion evoked by ACh (5.32x10$^{-3}$ M), high $K^{+}$(5.6x10$^{-2}$ M), DMPP (10$^{-4}$ M for 2 min), McN-A-343 (10$^{-4}$ M for 2 min), cyclopiazonic acid (10$^{-5}$ M for 4 min) and Bay-K-8644 (10$^{-5}$ M for 4 min). Also, in the presence of $\beta$,${\gamma}$-methylene adenosine-5'-triphosphate (MATP), which is also known to be a selective $P_{2x}$-purinergic receptor agonist, showed a similar inhibition elf CA release evoked by ACh, high potassium, DMPP, McN-A-343, Bay-K-8644 and cyclopiazonic acid. However, in adrenal glands preloaded with 20$\mu$M NECA for 20 min under the presence of 20$\mu$M 3-isobutyl-1-methyl-xanthine (IBMX), an adenosine receptors antagonist, CA secretory responses evoked by ACh, high potassium, DMPP, McN-A-343, Bay-K-8644 and cyclopiazonic acid were much recovered in comparison to the case of NECA-treatment only. Taken together, these results indicate that NECA causes the marked inhibition of CA secretion evoked by stimulation of cholinergic (both nicotinic and muscarinic) receptors as well as by membrane depolarization. This inhibitory effect may be mediated by inhibiting influx of extracellular calcium and release in intracellular calcium in the rat adrenomedullary chromaffin cells through the adenosine receptor stimulation. Therefore, it is suggested that the inhibitory mechanism of adenosine receptor stimulation may play a modulatory role in regulating CA secretion.n.n.

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Dielectric and Optical Properties of Amorphous Hafnium Indium Zinc Oxide Thin Films on Glass Substrates

  • Shin, Hye-Chung;Seo, Soon-Joo;Denny, Yus Rama;Lee, Kang-Il;Lee, Sun-Young;Oh, Suhk-Kun;Kang, Hee-Jae;Heo, Sung;Chung, Jae-Gwan;Lee, Jae-Cheol
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.08a
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    • pp.225-225
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    • 2011
  • The dielectric and optical properties of GaInZnO (GIZO), HfInZnO (HIZO) and InZnO (IZO) thin films on glass by RF magnetron sputtering method were investiged using reflection electron energy loss spectroscopy (REELS). The band gap was estimated from the onset values of REELS spectra. The band gaps of GIZO, HIZO and IZO thin films are 3.1 eV, 3.5 eV and 3.0 eV, respectively, Hf and Ga incorporated into IZO results in an increase in the energy band gap of IZO by 0.5 eV and 0.1 eV. The dielectric functions were determined by comparing the effective cross section determined from experimental REELS with a rigorous model calculation based on the dielectric response theory, using available software package, good agreement between the experimental and fitting results gives confidence in the accuracy of the determined dielectric function. The main peak of Energy Loss Function (ELF) obtained from IZO shows at 18.42 eV, which shifted to 19.43 eV and 18.15 eV for GIZO and HIZO respectively, because indicates the corporation of cation Ga and Hf in the composition. The optical properties represented by the dielectric function e, the refractive index n, the extinction coefficient k, and the transmission coefficient, T of HIZO and IZO thin films were determined from a quantitative analysis of REELS. The transmission coefficient was increased to 93% and decreased to 87% in the visible region with the incorporation of Hf and Ga in the IZO compound.

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Analysis of Piled Piers Considering Riverbed Scouring (교각세굴을 고려한 말뚝기초의 해석)

  • Jeong, Sang-Seom;Suh, Jung-Ju;Won, Jin-Oh
    • Journal of the Korean Geotechnical Society
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    • v.18 no.3
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    • pp.43-50
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    • 2002
  • This paper describes a simplified numerical procedure for analyzing the response of bridge pier foundations due to riverbed scouring. A computationally efficient algorithm to analyze the behavior of a pile group is proposed by considering soil-pile, pile-cap, and pile-fluid interactions. The complex phenomenon of the pile-soil interaction is modeled by discrete nonlinear soil springs (p-y, t-z and q-z curves). The pile-cap interaction is considered by geometric configuration of the piles in a group and connectivity conditions between piles and the cap. The pile-fluid interaction is incorporated into the procedure by reducing the stiffness of the soil-pile reactions as a result of nonlinearity and degradation of the soil stiffness with river bridge scouring. Through the numerical study, it is shown that the maximum bending moment increases with increasing scour depth. Thus it is desirable to check the stability elf pile groups based on soil-pile and pile-cap interactions by considering scouring depth in the riverbed.

Design of a Magnetic Field Source for In Vivo Experiments at Extremely Low Frequency (생체 실험용 극저주파 자기장 발생 장치의 설계)

  • 김정호;김윤명
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.8
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    • pp.871-877
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    • 2003
  • In this paper, the design parameters for the magnetic field source at extremely low frequency are proposed. This facility can be used fur in vivo experiments with small animals to investigate biological response to the driving magnetic fields. In case that the exposed animals are motionless, the animals may be affected by the directivity of driving field. To avoid this effect, a 2-axis ELF magnetic field driving apparatus was designed. The optimum location and number of turns of each coil were obtained by numerical analysis. Applying these data to the MATLAB code(for computation), the magnetic field distribution was obtained. The calculation result fur a well-designed facility showed that the space in which the amplitude of the magnetic field lies within the 95 % of the magnetic field distribution was more than 60 % of each axis length.

A Study on the Correlation between of Bone Mineral Density and Cold Hypersensitivity of Hands (골밀도와 수냉증과의 상관성 연구)

  • Lee, Dong-Nyung;Lee, Jeong-Im;Go, Ho-Yeon;Kim, Hyung-Jun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.28 no.4
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    • pp.11-20
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    • 2015
  • Objectives The purpose of this study was to examine the relationship between cold hypersensitivity and bone mineral density. Methods 28 outpatients who visited OO University Oriental Hospital from July 11th, 2013 to August 28th, 2013 were analyzed. Patients were subjected to thermometer, and those with thermal difference greater than 0.3 ℃ between upper arm and palm and also with more than VAS 4 of cold hypersensitivity were diagnosed with cold sensitivity. Lumba spine (L2-4) and heel bone measurement were obtained on dual energy X-ray absorptiometry (DEXA) and Quantitative Computed Tomography (QCT). Results 1. There was statistically significant correlation between T-score of DEXA and body weight (0.522), BMI (0.643), OSTA (Osteoporosis elf-assesment Tool for Asians, 0.579), BMI, T-score and Z-score of QCT. OSTA and T-score of QCT (0.521) also had statistically significance. 2. There was no statistically significant correlation between body fat, abdominal obesity rate, degree of cold hypersensitivity, upper arm and palm's temperature difference, palm temperature, height and Z-score, T-score of QCT or T-sore of DEXA. Conclusions Bone mineral density was lower in women who had cold hypersensitivity of hand and feet. But there was no statistically significant correlation between bone mineral density and degree of cold hypersensitivity, upper arm and palm’s temperature difference.

Improvement of Two-Dimensional Terahertz Image by Digital Image Processing (데이터 처리를 통한 테라헤르츠 (THz) 파의 2차원 이미지 개선)

  • Shon, Chae-Hwa;Jin, Yun-Sik;Jeon, Seuk-Gy;Kim, Keun-Ju;Jung, Sun-Shin;Yong, Chong-Won
    • Korean Journal of Optics and Photonics
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    • v.16 no.6
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    • pp.500-507
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    • 2005
  • Two-dimensional (2D) images that are produced by terahertz (THz) irradiation we presented. It is possible to obtain 2D image of various materials by observing the amplitude and the phase of the THz signals which go through them. Better images are produced by combining the amplitude and phase of the signal rather than using only one of these. Homomorphic filtering that is one elf the well-known technique of digital image signal processing is effective to reduce the noise signal and can provide better quality images. The results can be applied to real-time imaging afterwards.

High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in Arabidopsis

  • Kim, Chanhee;Kim, Sun Ji;Jeong, Jinkil;Park, Eunae;Oh, Eunkyoo;Park, Youn-Il;Lim, Pyung Ok;Choi, Giltsu
    • Molecules and Cells
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    • v.43 no.7
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    • pp.645-661
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    • 2020
  • Leaf senescence is a developmental process by which a plant actively remobilizes nutrients from aged and photosynthetically inefficient leaves to young growing ones by disassembling organelles and degrading macromolecules. Senescence is accelerated by age and environmental stresses such as prolonged darkness. Phytochrome B (phyB) inhibits leaf senescence by inhibiting phytochrome-interacting factor 4 (PIF4) and PIF5 in prolonged darkness. However, it remains unknown whether phyB mediates the temperature signal that regulates leaf senescence. We found the light-activated form of phyB (Pfr) remains active at least four days after a transfer to darkness at 20℃ but is inactivated more rapidly at 28℃. This faster inactivation of Pfr further increases PIF4 protein levels at the higher ambient temperature. In addition, PIF4 mRNA levels rise faster after the transfer to darkness at high ambient temperature via a mechanism that depends on ELF3 but not phyB. Increased PIF4 protein then binds to the ORE1 promoter and activates its expression together with ABA and ethylene signaling, accelerating leaf senescence at high ambient temperature. Our results support a role for the phy-PIF signaling module in integrating not only light signaling but also temperature signaling in the regulation of leaf senescence.