• 한국가스학회지
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• 제22권6호
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• pp.28-33
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• 2018

최근 들어 정부는 도시가스 미공급지역 해소 및 소규모 공급지역의 경제성 확보를 위해 준저압 공급을 확대하고 있다. 주로 중앙 저장 탱크에서 매설 배관으로 각 세대에 공급하고 있는데 타공사에 의한 매설 배관의 파손 시 가스의 누출을 차단할 방법으로 배관 파손에 의한 과류를 차단할 수 있는 밸브의 필요성이 대두되고 있다. 이 연구를 위해 System CFD Code인 Flownex를 이용하였으며 실제 과류차단밸브에 해당되는 Component를 개발 완료하였다. 본 연구를 진행하면서 Flownex의 정확도를 검증하기 위해 실험값과 비교 하였으며 2% 내외의 오차율을 확인하였고 본 연구를 위해 사용이 가능한 것으로 판단되었다. 본 연구에서는 마을 단위의 LPG 공급 배관망을 선정하여 Modeling을 하였으며 주배관에서 세대로 인입되는 가지관의 이음 부위에 임으로 과류차단밸브 Component를 설치하였다. 주 배관에서 세대까지 가장 긴 배관을 선택하여 세대 인입 직전에 배관을 임으로 파손시켜 과류가 발생하도록 시나리오를 정하였다. 배관이 파손됨에 따라 과류가 발생하게 되고 과류차단밸브가 작동하게 되는데 이 때 과류차단 밸브의 작동이 타 배관에 미치는 영향 및 오작동 유무를 분석하였다.

• Journal of Veterinary Science
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• 제24권5호
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• pp.67.1-67.15
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• 2023

Background: Feline immunodeficiency virus (FIV) causes an acquired immunodeficiency-like syndrome in cats. FIV is latent. No effective treatment has been developed for treatment the infected cats. The first and second generations non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV treatment, nevirapine (NVP) and efavirenz (EFV), and rilpivirine (RPV), were used to investigate the potential of NNRTIs for treatment of FIV infection. Objective: This study aims to use experimental and in silico approaches to investigate the potential of NNRTIs, NVP, EFV, and RPV, for inhibition of FIV reverse transcriptase (FIV-RT). Methods: The FIV-RT and human immunodeficiency virus reverse transcriptase (HIV-RT) were expressed and purified using chromatography approaches. The purified proteins were used to determine the IC₅₀ values with NVP, EFV, and RPV. Surface plasmon resonance (SPR) analysis was used to calculate the binding affinities of NNRTIs to HIV-RT and FIV-RT. The molecular docking and molecular dynamic simulations were used to demonstrate the mechanism of FIV-RT and HIV-RT with first and second generation NNRTI complexes. Results: The IC₅₀ values of NNRTIs NVP, EFV, and RPV against FIV-RT were in comparable ranges to HIV-RT. The SPR analysis showed that NVP, EFV, and RPV could bind to both enzymes. Computational calculation also supports that these NNRTIs can bind with both FIV-RT and HIV-RT. Conclusions: Our results suggest the first and second generation NNRTIs (NVP, EFV, and RPV) could inhibit both FIV-RT and HIV-RT.

• 한국가스학회지
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• 제24권3호
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• pp.54-62
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• 2020

구미 휴브글로벌 AHF 누출사고를 보면서 화학 사고가 우리 사회에 미치는 영향이 얼마나 큰지 경험한 바 있다. 이후로 여러 분야에서 화학 사고에 관한 많은 연구가 수행되고 있다. 사용처에서는 공정 시스템에 대한 개선방안을 찾아 현장에 적용하고자 했고 안전분야에서는 피해 영향 분석을 통한 안전성 향상을 연구하여 비상대응에 적용하여 피해 영향을 줄이고자 하였다. 본 연구에서는 이충전 작업 시 일어나는 화학사고에 신속하게 대응할 수 있는 기계적 안전장치를 적용하여 AHF ISO Tank의 안전성을 높이고자 하였다. 연구의 수행으로는 우리나라에 연간 유통되는 AHF의 수입량의 규모와 운반의 수단으로 사용되는 ISO Tank의 운송 물량을 조사하고 AHF ISO Tank의 구조 및 Unloading 절차를 조사하였다. 많은 유형의 탱크로리를 조사하는 과정에서 AHF ISO Tank 구조와 작업 절차가 유사한 염소 탱크로리에 기계적 안전장치인 EFV(과류 방지 밸브)가 설치되어 있는 것을 확인하였다. EFV의 AHF ISO Tank에 적용성과 도입 시 안전기능인 긴급차단에 대한 성능을 휴브글로벌 사고와 2018년에 울산에서 발생한 염소 Tank lorry의 사고사례를 비교 조사하여 실제 사고에서 얻은 자료로 검정할 수 있었다. 사고사례와 적용성 등을 비교한 결과, AHF ISO Tank에 화학사고 피해를 감소시키고 사고를 조기에 수습할 할 수 있는 기계적 안전장치인 EFV를 도입할 것을 제안하며 휴브글로벌 사고와 같은 화학 사고에 도움이 되고자 한다.

• Journal of Advanced Marine Engineering and Technology
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• 제28권7호
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• pp.1072-1081
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• 2004

This paper is to investigate on the effects of the hole size of spring type EFV(excessive flow valve) for automobiles The analytical and experimental methods were employed to measure the discharge coefficient. choked flowrate and Pressure wave in a bombe, line and vaporizor The size of EFV was determined to meet the legally permitted limits with the capacity of engine displacement up to 2000cc, according to the obtained discharge coefficient. The Purpose of this paper is 1) to find causes of bad acceration performance in LPG engines 2) to find optimal design determination of spring coefficient and orifice hole size of excessive flow valve in LPG engine 3) to find pressure wave of bombe, line and vaporizer through expeimental verification. Experimental results indicated that increase of orifice size 0.5mm to 1mm be caused to increase discharge coefficient, and choked flow rate and decrease operation range of difference pressure wave.

• 동의생리병리학회지
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• 제25권3호
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• pp.510-515
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• 2011

This study was conducted to evaluate the depigmenting properties of ethanol extract from a Fritillaria verticillata Willd. (EFV) in B16F10 cells. Fritillaria verticillata Willd., a perennial herbaceous plant, has been used as a stimulator of mammary gland, expectorant, blood pressure depressant, antitussive agents in Korean herbal medicine. In the present study, we observed that melanin synthesis of B16F10 cells were significantly decreased by EFV without cytotoxicity. However, EFV could not suppress tyrosinase activity in B16F10 cells and mushroom tyrosinase activity. Furthermore, EFV did not effect the protein expression of tyrosinase, tyrosinase-related protein -1 (TRP-1), and TRP-2. These results suggest that EFV inhibited melanin synthesis and the hypopigmentary effect of EVF was not due to regulation of tyrosinase protein.

• 한국자동차공학회논문집
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• 제23권5호
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• pp.537-544
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• 2015

The effects of the modification of hybrid vehicle components on diesel exhaust emissions were investigated in this study. We examined the changes in exhaust emissions and the fuel consumption (FC) caused by the modification of generator (alternator) and motors. Exhaust emissions such as black carbon (BC), HC, $NO_X$ and $CO_2$ were measured not only in idle state but also on an actual urban road as well as on a chassis dynamometer. BC, $NO_X$ and HC emissions increased by 95%, 27% and 34% respectively when the generator charged the battery in the idle condition. BC and FC decreased in hybrid mode on the actual urban road partly because the motors were used to assist the diesel engine. In addition, the decreases in exhaust emissions and FC were also evident in the hybrid mode when the vehicle was tested on the chassis dynamometer.

• 한국자동차공학회논문집
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• 제18권2호
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• pp.122-128
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• 2010

To meet the NOx limit without a penalty of fuel consumption, urea-SCR system is currently regarded as promising NOx reduction technology for diesel engines. SCR system has to achieve maximal NOx conversion in combination with minimal $NH_3$ slip. In this study, the performance characteristics of urea-SCR system with open loop control were assessed in the European Transient Cycle(ETC) for heavy duty diesel engine. The SCR inlet temperaure varied in the range of 200 to $340^{\circ}C$ in the ETC cycle. Open loop control calculated the urea flow rate based on the NOx and NSR map which gave for each combination of SCR inlet temperature and space velocity the normalized $NH_3$ to NOx stoichiometric ratio which resulted in a steady-state $NH_3$ slip of 20ppm. During the ETC cycle, the open loop control with the optimized NSR offset achieved NOx reduction of 80% while keeping the average $NH_3$ slip below 10ppm and maximum 20ppm. It was also found that NOx sensor was cross-sensitive to $NH_3$ and a control strategy for cross-sensitivity compensation was required in order to use a NOx sensor as feedback device.

• 한국기계가공학회지
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• 제20권2호
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• pp.14-22
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• 2021

A plan for the development of reliability-based ROK amphibious assault vehicles is proposed. By analyzing the development case of the U.S. EFV, considerations for the successful development of the next-generation Korea Forces amphibious assault vehicle are presented. If the vehicle reliability can be improved to the level of the fourth highest priority electric unit for power units, suspensions, decelerators, and body groups, which have the highest priority among fault frequency items, a system level MTBF of 36.4%↑ can be achieved, and the operational availability can be increased by 3.5%↑. The next-generation amphibious assault vehicles must fulfill certain operating and performance requirements, the underlying systems must be built, and sequencing of the hybrid engine and the modular concept should be considered. Along with big-data- and machine-learning-based failure prediction, machine maintenance based on augmented reality/virtual reality and remote maintenance should be used to improve the ability to maintain combat readiness and reduce lifecycle costs.

• 한국자동차공학회논문집
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• 제19권2호
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• pp.50-56
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• 2011

To meet the NOx limit without a penalty of fuel consumption, Urea-SCR system is currently regarded as promising NOx reduction technology for diesel engines. SCR system has to achieve maximal NOx conversion in combination with minimal $NH_3$ slip. In this study, map based open loop control for urea injection was developed and assessed in the European Transient Cycle (ETC) for heavy duty diesel engine. The basic urea quantity set-value which was calculated using the look up tables of engine out NOx, exhaust flow rate and optimum NSR resulted in NOx reduction of 80% and the average $NH_3$ slip of 24 ppm and maximum of 79 ppm. In order to reduce $NH_3$ slip, $NH_3$ storage control algorithm was applied to correct the basic urea quantity and reduced $NH_3$ slip levels to the average 15 ppm and maximum 49 ppm while keeping NOx reduction of 76%. With high and increasing SCR temperature, the $NH_3$ storage capacity decreases, which leads to $NH_3$ slip. The resulting $NH_3$ slip peak can be avoided by stopping or significantly reducing the urea injection during the SCR temperature gradient is over $30^{\circ}C/min$.