• Journal of the Korean Institute of Gas
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• v.22 no.6
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• pp.28-33
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• 2018

Currently, the government has been expanding the supply of semi-low-pressure in order to solve the problems of unsupplied area of city gas and to secure the economical efficiency of small supplied area. It is mainly supplied from the central storage tank to each household by buried piping. It is necessary to provide such a shutoff valve that can block the excess flow gas due to pipeline leak or rupture when piping is damaged by other construction. For this study, System CFD code named Flownex has been used and a component corresponding to the actual EFV was developed. We compared Flownex results with experimental data to verify the accuracy of Flownex and confirmed the error rate to be around 2%. In this study, pipeline network modeling was done by selecting the LPG supply pipeline in a village and installed the component of the EFV at each junction. We selected the longest pipeline from the main pipeline and set scenarios so that the excess flow occurs by that the pipeline is ruptured before entering the household. The excess flow occurs by the pipeline rupture and the EFV is closed. At this time, we analyzed backflow effects to the other pipeline by closing EFV.

• Journal of Veterinary Science
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• v.24 no.5
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• pp.67.1-67.15
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• 2023

Background: Feline immunodeficiency virus (FIV) causes an acquired immunodeficiency-like syndrome in cats. FIV is latent. No effective treatment has been developed for treatment the infected cats. The first and second generations non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV treatment, nevirapine (NVP) and efavirenz (EFV), and rilpivirine (RPV), were used to investigate the potential of NNRTIs for treatment of FIV infection. Objective: This study aims to use experimental and in silico approaches to investigate the potential of NNRTIs, NVP, EFV, and RPV, for inhibition of FIV reverse transcriptase (FIV-RT). Methods: The FIV-RT and human immunodeficiency virus reverse transcriptase (HIV-RT) were expressed and purified using chromatography approaches. The purified proteins were used to determine the IC₅₀ values with NVP, EFV, and RPV. Surface plasmon resonance (SPR) analysis was used to calculate the binding affinities of NNRTIs to HIV-RT and FIV-RT. The molecular docking and molecular dynamic simulations were used to demonstrate the mechanism of FIV-RT and HIV-RT with first and second generation NNRTI complexes. Results: The IC₅₀ values of NNRTIs NVP, EFV, and RPV against FIV-RT were in comparable ranges to HIV-RT. The SPR analysis showed that NVP, EFV, and RPV could bind to both enzymes. Computational calculation also supports that these NNRTIs can bind with both FIV-RT and HIV-RT. Conclusions: Our results suggest the first and second generation NNRTIs (NVP, EFV, and RPV) could inhibit both FIV-RT and HIV-RT.

• Journal of the Korean Institute of Gas
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• v.24 no.3
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• pp.54-62
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• 2020

Watching the leakage accident of the Gumi Hube Global AHF(Anhydrous fluoric Acid), I experienced how much chemical accidents affect on our society. Since then, many studies have been conducted on chemical accident in many fields. The use department wanted to find improvement plans for the process system and apply them to the field. The safety field wanted to study improvement of safety through the analysis of damage effects and apply them to emergency response to reduce damage effects. In this study, Mechanical safe devices have been applied which can respond quickly to chemical accidents occurring during the charging operation to enhance the safety of the AFH ISO Tank(Anhydrous fluoric Acid International Organization for Standardization Tank). Investigation of similar tanks confirmed that other chlorine tanks with the same working procedure as AHF ISO Tank have a mechanical safety device, EFV(Excess Flow Valve). Applicability and performance for emergency shutdown when EFV is introduced in AHF ISO Tank can be verified by comparing and examining the accident situation of Hube Global Accident and the accident in Ulsan 2018. Comparing accident cases, expected performance and applicability, It is suggested that EFV, a mechanical safety device that can reduce damage from chemical accidents to the tank and handle accidents early, should be introduced to the tank.

• Journal of Advanced Marine Engineering and Technology
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• v.28 no.7
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• pp.1072-1081
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• 2004

This paper is to investigate on the effects of the hole size of spring type EFV(excessive flow valve) for automobiles The analytical and experimental methods were employed to measure the discharge coefficient. choked flowrate and Pressure wave in a bombe, line and vaporizor The size of EFV was determined to meet the legally permitted limits with the capacity of engine displacement up to 2000cc, according to the obtained discharge coefficient. The Purpose of this paper is 1) to find causes of bad acceration performance in LPG engines 2) to find optimal design determination of spring coefficient and orifice hole size of excessive flow valve in LPG engine 3) to find pressure wave of bombe, line and vaporizer through expeimental verification. Experimental results indicated that increase of orifice size 0.5mm to 1mm be caused to increase discharge coefficient, and choked flow rate and decrease operation range of difference pressure wave.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.510-515
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• 2011

This study was conducted to evaluate the depigmenting properties of ethanol extract from a Fritillaria verticillata Willd. (EFV) in B16F10 cells. Fritillaria verticillata Willd., a perennial herbaceous plant, has been used as a stimulator of mammary gland, expectorant, blood pressure depressant, antitussive agents in Korean herbal medicine. In the present study, we observed that melanin synthesis of B16F10 cells were significantly decreased by EFV without cytotoxicity. However, EFV could not suppress tyrosinase activity in B16F10 cells and mushroom tyrosinase activity. Furthermore, EFV did not effect the protein expression of tyrosinase, tyrosinase-related protein -1 (TRP-1), and TRP-2. These results suggest that EFV inhibited melanin synthesis and the hypopigmentary effect of EVF was not due to regulation of tyrosinase protein.

• Transactions of the Korean Society of Automotive Engineers
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• v.23 no.5
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• pp.537-544
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• 2015

The effects of the modification of hybrid vehicle components on diesel exhaust emissions were investigated in this study. We examined the changes in exhaust emissions and the fuel consumption (FC) caused by the modification of generator (alternator) and motors. Exhaust emissions such as black carbon (BC), HC, $NO_X$ and $CO_2$ were measured not only in idle state but also on an actual urban road as well as on a chassis dynamometer. BC, $NO_X$ and HC emissions increased by 95%, 27% and 34% respectively when the generator charged the battery in the idle condition. BC and FC decreased in hybrid mode on the actual urban road partly because the motors were used to assist the diesel engine. In addition, the decreases in exhaust emissions and FC were also evident in the hybrid mode when the vehicle was tested on the chassis dynamometer.

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.2
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• pp.122-128
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• 2010

To meet the NOx limit without a penalty of fuel consumption, urea-SCR system is currently regarded as promising NOx reduction technology for diesel engines. SCR system has to achieve maximal NOx conversion in combination with minimal $NH_3$ slip. In this study, the performance characteristics of urea-SCR system with open loop control were assessed in the European Transient Cycle(ETC) for heavy duty diesel engine. The SCR inlet temperaure varied in the range of 200 to $340^{\circ}C$ in the ETC cycle. Open loop control calculated the urea flow rate based on the NOx and NSR map which gave for each combination of SCR inlet temperature and space velocity the normalized $NH_3$ to NOx stoichiometric ratio which resulted in a steady-state $NH_3$ slip of 20ppm. During the ETC cycle, the open loop control with the optimized NSR offset achieved NOx reduction of 80% while keeping the average $NH_3$ slip below 10ppm and maximum 20ppm. It was also found that NOx sensor was cross-sensitive to $NH_3$ and a control strategy for cross-sensitivity compensation was required in order to use a NOx sensor as feedback device.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.2
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• pp.14-22
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• 2021

A plan for the development of reliability-based ROK amphibious assault vehicles is proposed. By analyzing the development case of the U.S. EFV, considerations for the successful development of the next-generation Korea Forces amphibious assault vehicle are presented. If the vehicle reliability can be improved to the level of the fourth highest priority electric unit for power units, suspensions, decelerators, and body groups, which have the highest priority among fault frequency items, a system level MTBF of 36.4%↑ can be achieved, and the operational availability can be increased by 3.5%↑. The next-generation amphibious assault vehicles must fulfill certain operating and performance requirements, the underlying systems must be built, and sequencing of the hybrid engine and the modular concept should be considered. Along with big-data- and machine-learning-based failure prediction, machine maintenance based on augmented reality/virtual reality and remote maintenance should be used to improve the ability to maintain combat readiness and reduce lifecycle costs.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.2
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• pp.50-56
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• 2011

To meet the NOx limit without a penalty of fuel consumption, Urea-SCR system is currently regarded as promising NOx reduction technology for diesel engines. SCR system has to achieve maximal NOx conversion in combination with minimal $NH_3$ slip. In this study, map based open loop control for urea injection was developed and assessed in the European Transient Cycle (ETC) for heavy duty diesel engine. The basic urea quantity set-value which was calculated using the look up tables of engine out NOx, exhaust flow rate and optimum NSR resulted in NOx reduction of 80% and the average $NH_3$ slip of 24 ppm and maximum of 79 ppm. In order to reduce $NH_3$ slip, $NH_3$ storage control algorithm was applied to correct the basic urea quantity and reduced $NH_3$ slip levels to the average 15 ppm and maximum 49 ppm while keeping NOx reduction of 76%. With high and increasing SCR temperature, the $NH_3$ storage capacity decreases, which leads to $NH_3$ slip. The resulting $NH_3$ slip peak can be avoided by stopping or significantly reducing the urea injection during the SCR temperature gradient is over $30^{\circ}C/min$.