• Korean Journal of Acupuncture
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• v.19 no.1
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• pp.77-84
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• 2002

목적 : 소아의 정신적 및 신체적 발달지연에 사용되고 있는 신기환이 해마의 신경세포 생성에 미치는 영향을 관찰하고자 하였다. 방법 : 신기환이 세포생성에 미치는 영향을 알아보기 위하여 해마 세포인 HiB5에 신기환을 처리, 배양하여 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay를 통해서 세포생성을 관찰하였다. 또한 3주령의 Sprague-Dawley (S-D)계 흰쥐의 중완혈에 신기환 약침을 자침후 해마의 치상회에서 bromodeoxyuridine (BrdU) immunohistochemistry를 시행하여 세포생성을 관찰하였다. 결과 : HiB5 배양세포에서는 신기환을 처리시 배양시간과 농도별로 세포생성율이 증가하였다. 또한, 대조군의 치상회에서 BrdU 양성세포수는 $128.50{\pm}9.53$, 1 mg/kg 신기환 자침군은 $157.08{\pm}10.82$ 및 10 mg/kg 신기환 자침군은 $204.80{\pm}17.68$로 나타났다. 이러한 결과로 신기환은 어린 S-D계 흰쥐의 치상회에서 세포생성을 증가시키는 것으로 사려된다.

• Journal of Acupuncture Research
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• v.18 no.6
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• pp.206-214
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• 2001

The purpose of this study was to determine the effects of Puerariae flos herb-acupuncture on hippocampal neural cell proliferation. Sprague-Dawley rats were randomly assigned into 4 groups; control group, control with herb-acupuncture group, alcohol group, alcohol with herb-acupuncture group group. Control groups were received with NaCl, while alcohol intoxication groups were injected intraperitoneally with alcohol (2 g/㎏) twice per day for 3 days. Herb-acupuncture groups were injected on Zhongwan (CV 12) for 5 consecutive days. Bromo-deoxyuridine (BrdU) was injected into all animal per day for 5 days. For the detection of BrdU-positive cells in dentate gyrus of hippocampus, immunohistochemistry was performed. In alcohol group, a significant decrease in BrdU-positive cells was observed compared to control group. In alcohol with herb-acupuncture group, BruU-positive cells increased significantly compared to alcohol group. In conclusion, the present results revealed that new cell proliferation is enhanced in the dentate gyros of young Sprague-Dawley rats through Puerariae flos herb-acpuncuture in an acute alcoholic intoxication condition.

• Journal of Society of Preventive Korean Medicine
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• v.16 no.3
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• pp.53-73
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• 2012

Objectives : The inclusion of Korean Medicine in the national health care system led to the need of a serious discussion on its modernization. This paper looked at how these discussions were progressed. Especially, a difference in the meaning of 'science' in the 1950s and the 1990s was observed. Methods : Articles related to the medical dispute between Korean and Western Medicine in "EE LIM", especially the ones from the 1950s, were selected, classified and analyzed. Research papers on Evidence-Based Medicine were also analyzed. Evidence-Based Medicine was a new medical research methodology in the 1990s. Articles on Evidence-Based Medicine were searched and selected from journal databases: DBpia, KISS, RISS, and OASIS. Results : The problem of establishment of modernity of Korean Medicine in the recent times was addressed in the context of scientification and systematization. Accordingly, the academic societies of Korean Medicine aimed for scientification. But efforts to secure the identity of Korean Medicine opposed to western science were also made. Meanwhile, Evidence-Based Medicine established in 1992 presented a different concept of science. This led to a new means of acknowledgement of Korean Medicine in the modern society. Conclusions : The modernization process of Korean Medicine up to now was a course of scientification. But as this process did not fully reflect its characteristics, the modernization of Korean Medicine still remains a pending question. A modern study methodology that fully reflects the identity of Korean Medicine needs to be established.

• Journal of Korea Technology Innovation Society
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• v.21 no.1
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• pp.300-330
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• 2018

Enterprises' participation in the collaboration research is one of the effective and typical methods through which technologies go into the market or are transferred to other sectors. This study reviews enterprises' participated collaboration research and analyzes their network for disaster and safety management area. From 2005 to 2016, 786 technical papers from four representative journals for disaster and safety management in Korea are compiled based on the authors whose affiliations are from enterprises. During the research period, collaboration research is found to be in an increasing trend in general. However, the number of technical papers with three or less authors is in a decreasing trend, whereas that with four or more authors is in an increasing trend. This fact implies that the range of enterprises' collaboration research is widening. Technical paper productivity and each entity's collaboration network are evaluated using participation-weight based author score. Over the research period, a few universities, which attract most of the enterprises, are found to have higher productivities and centralities. Public enterprises show higher participation weights. Also, sectors such as construction, engineering, and electronics demonstrate higher weights. This study is particularly meaningful because enterprises' participation status in collaboration research for disaster and safety management area is systematically analyzed for the first time in Korea. The network analysis result from this study will be especially helpful in establishing technology transfer strategy.

• Journal of The Korean Society of Grassland and Forage Science
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• v.26 no.3
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• pp.139-146
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• 2006

This experiment was conducted to determine the effect of microbial inoculant on the quality of round baled grass silage at experimental field of Grassland and Forages Division, National Livestock Research Institute, RDA, Suwon from 1997 to 1998. The experiment was consist of randomized block design with three replications. The treatments were three different inoculant (control, inoculant A, B and C). The contents of ether extract(EE), crude protein(CP) and in vitro dry matter digestibility(IVDMD) in inoculant treatment plots were higher than those in control. Silages treated by Inoculant A, Band C had significantly lower acidity than that of control silage (p<0.05). Dry matter(DM) content of control silage was higher than those of inoculant treated silage. There were significant differences in organic acid contents among treatments(p<0.05). Lactic acid was increased with inoculant treatment, but, acetic and butyric acid was decreased. The DM loss of all silages were decreased with inoculant treatment and quality grade of inoculant treated silage was higher than that of control. Results of this study indicate that addition of microbial inoculant will improve the fermentation and quality of round baled grass silage.

• Korean Journal of Clinical Laboratory Science
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• v.49 no.3
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• pp.214-219
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• 2017

Coal workers' pneumoconiosis (CWP) and chronic obstructive pulmonary disease (COPD) are characterized as chronic inflammation of the lung in miners exposed to coal mine dust. The aim of the present study was to compare the levels of serum lactate dehydrogenase (LD) and C-reactive protein (CRP) as the inflammatory indices between subjects with CWP and those with CWP and COPD (CWP+COPD), among a total of 97 subjects (27 control, 40 CWP, and 30 CWP+COPD patients). The mean levels of serum LD (165.7 vs 184.6 U/L, p=0.016) and CRP (0.08 vs 0.15 mg/dL, p=0.002) in subjects with CWP were higher than those of in subjects without CWP. The mean level of serum CRP (0.10 vs 0.19 mg/dL, p=0.008) in subjects with COPD was higher than that in subjects without COPD. In an analysis of covariance adjusted by age, the mean level of serum CRP showed statistical significance among the study groups, control, CWP, and CWP+COPD (0.07 vs 0.13 vs 0.19 mg/dL, p=0.005); the mean level of serum CRP in the CWP+COPD group was significantly higher than that of the control group (p=0.001). The results suggest that a high level of CRP in the serum may be associated with CWP and COPD in retired coal miners.

• Korean Journal of Remote Sensing
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• v.33 no.6_1
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• pp.961-970
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• 2017

Despite of large demand for high spatial resolution products of aerosol properties from satellite remote sensing, it has been very difficult due to the weak signal by a single pixel and higher noise from clouds. In this study, aerosol retrieval algorithm with the high spatial resolution ($500m{\times}500m$) was developed using Geostationary Ocean Color Imager (GOCI) data during the Korea-US Air Quality (KORUS-AQ) period in May-June, 2016.Currently, conventional GOCI Yonsei aerosol retrieval(YAER) algorithm provides $6km{\times}6km$ spatial resolution product. The algorithm was tested for its best possible resolution of 500 m product based on GOCI YAER version 2 algorithm. With the new additional cloud masking, aerosol optical depth (AOD) is retrieved using the inversion method, aerosol model, and lookup table as in the GOCI YAER algorithm. In some cases, 500 m AOD shows consistent horizontal distribution and magnitude of AOD compared to the 6 km AOD. However, the 500 m AOD has more retrieved pixels than 6 km AOD because of its higher spatial resolution. As a result, the 500 m AOD exists around small clouds and shows finer features of AOD. To validate the accuracy of 500 m AOD, we used dataset from ground-based Aerosol Robotic Network (AERONET) sunphotometer over Korea. Even with the spatial resolution of 500 m, 500 m AOD shows the correlation coefficient of 0.76 against AERONET, and the ratio within Expected Error (EE) of 51.1%, which are comparable to the results of 6 km AOD.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.3
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• pp.326-333
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• 2015

A tidal sandshoal, called 'Puldeung' in the Daeijackdo Marine Protected Area(DMPA), is facing erosion due to sand mining in the nearby coastal region. To monitor the morphologic change and erosion of Puldeung, a camera monitoring system was established at the top of Song-Ee Mountain in Daeijack Island. The system consists of 2 Cannon digital cameras, Eye-fi memory card/Long-Term Evolution wireless network, and solar power supply. The acquired camera images were analyzed to obtain the area of Puldeung by the following methods: geometric correction of image, identification of shoreline, areal measurement of Puldeung and its error estimation. To compare the Puldeung area with previously measured area of 1.79 km2 at tidal height of 137 cm in 2008 and of 1.59 km2 at tidal height of 148 cm in 2010, we selected images with same tidal heights. The Puldeung area was 1.37 and 1.23 km2 at the tidal height of 137 and 148 cm, respectively. The erosion at DMPA is very severe and thus it is imperative to initiate the morphodynamical study on the seasonal variation and long-term evolution of Puldeung as well as the causes and measures of Puldeung erosion.

• Clinical and Experimental Pediatrics
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• v.55 no.11
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• pp.438-444
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• 2012

Mucolipidosis II (ML II) or inclusion cell disease (I-cell disease) is a rarely occurring autosomal recessive lysosomal enzyme-targeting disease. This disease is usually found to occur in individuals aged between 6 and 12 months, with a clinical phenotype resembling that of Hurler syndrome and radiological findings resembling those of dysostosis multiplex. However, we encountered a rare case of an infant with ML II who presented with prenatal skeletal dysplasia and typical clinical features of severe secondary hyperparathyroidism at birth. A female infant was born at $37^{+1}$ weeks of gestation with a birth weight of 1,690 g (<3rd percentile). Prenatal ultrasonographic findings revealed intrauterine growth retardation and skeletal dysplasia. At birth, the patient had characteristic features of ML II, and skeletal radiographs revealed dysostosis multiplex, similar to rickets. In addition, the patient had high levels of alkaline phosphatase and parathyroid hormone, consistent with severe secondary neonatal hyperparathyroidism. The activities of ${\beta}$-D-hexosaminidase and ${\alpha}$-N-acetylglucosaminidase were moderately decreased in the leukocytes but were 5- to 10-fold higher in the plasma. Examination of a placental biopsy specimen showed foamy vacuolar changes in trophoblasts and syncytiotrophoblasts. The diagnosis of ML II was confirmed via GNPTAB genetic testing, which revealed compound heterozygosity of c.3091C>T (p.Arg1031X) and c.3456_3459dupCAAC (p.Ile1154GlnfsX3), the latter being a novel mutation. The infant was treated with vitamin D supplements but expired because of asphyxia at the age of 2 months.

• Journal of the Korean Magnetics Society
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• v.10 no.5
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• pp.237-245
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• 2000

Effects of B addition and heat treatment on the magnetic and magnetostrictive properties of amorphous SmFe$_2$ thin films are investigated. A significant improvement in the magnetostrictive properties at low magnetic fields is observed with the addition of B. This improvement, however, is achieved at a heavy cost of intrinsic properties such as saturation magnetostriction. For example, at a magnetic field of 30 Oe, magnetostriction of a thin film with a B content of 9.9 at.% is increased from 190 to 333 ppm, but saturation magnetostriction is decreased by more than 50 %. This result is in accord with the deterioration (reduction) of saturation magnetization and the improvement (reduction) of coercive force at this B content. The magnetostrictive properties are also improved by annealing and optimum annealing temperature is found to be in the range 300-400 $^{\circ}C$. The main reason for the improvement is mainly considered to be due to the reduction of coercive force caused by stress relief, not due to the ultrafine SmFe$_2$ precipitates which were originally expected to form by annealing.