• Journal of Society of Preventive Korean Medicine
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• v.17 no.3
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• pp.19-30
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• 2013

This study was aimed to develop a new formula for herbal medicine-safety classification in terms of evidence-based medicine. Recently, human equivalent dose(HED)-based therapeutic index was developed for herbal medicine-safety classification by transforming $LD_{50}$ to HED. However, the use of the $ED_{50}$ and $LD_{50}$ to derive the therapeutic index may be misleading as to safety, depending on the slope of the dose-response curves for therapeutic and lethal effects. To overcome this deficiency, HED-based MOS(Margin of Safety)was developed and suggested in this study. The HED-based MOS developed by using $LD_1$, changing to ALD(approximate lethal dose), and $ED_{99}$. The HED-based MOS seems to be more useful and safer than HED-based therapeutic index since its values for several herbal medicines are basically two times less than the values from HED-based therapeutic index. Thus, HED-based MOS can be a good example of Evidence-based approach for herbal medicine-safety classification.

• Journal of Korean Library and Information Science Society
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• v.43 no.4
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• pp.5-22
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• 2012

The purpose of this study aims to provide possible suggestions for the improvement of KDC 5th ed. in Jurisprudence Field. The research methods are as follows. First, to analyze academic fields in Jurisprudence, the contents of Jurisprudence introductory books are investigated. Second, to find out the problem of KDC Jurisprudence field, comparative analysis is done on the three classification schemes - KDC, DDC and NDC. Third, curriculum of domestic law schools are reflected. If above suggestions are adopted, effective literature classification scheme which is suited to domestic circumstances will be certainly prepared.

• Journal of Korean Library and Information Science Society
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• v.45 no.3
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• pp.415-440
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• 2014

This study intends to make a comprehensive inquiry into the meaning and limitations of Discovery, and to explore how to make full use of Discovery in library cataloging. To this end, first discussed is the meaning of Discovery, which has a variety definitions. For the quality evaluation, 5 criteria were developed on the basis of literature review. Then this study conducted the quality evaluation on the basis of previously developed 5 criteria and usefulness of Discovery in library catalogs is thoroughly discussed. Based on these, the final discussion includes strategies for Korean LIS scholars and library practitioners to consider when applying Discovery as an integrated search tool.

• Journal of Electrical Engineering and Technology
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• v.10 no.4
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• pp.1804-1814
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• 2015

In order to explore the characteristics of electrons in DC negative corona discharge, an improved plasma chemical model is presented for the simulation of bar-plate DC corona discharge in dry air. The model is based on plasma hydrodynamics and chemical models in which 12 species are considered. In addition, the photoionization and secondary electron emission effect are also incorporated within the model as well. Based on this model, electron mean energy distribution (EMED), electron density distribution (EDD), generation and dissipation rates of electron at 6 typical time points during a pulse are discussed emphatically. The obtained results show that, the maximum of electron mean energy (EME) appears in field ionization layer which moves towards the anode as time progresses, and its value decreases gradually. Within a pulse process, the electron density (ED) in cathode sheath almost keeps 0, and the maximum of ED appears in the outer layer of the cathode sheath. Among all reactions, R1 and R2 are regarded as the main process of electron proliferation, and R₂₂ plays a dominant role in the dissipation process of electron. The obtained results will provide valuable insights to the physical mechanism of negative corona discharge in air.

• Journal of Microbiology and Biotechnology
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• v.27 no.6
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• pp.1065-1070
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• 2017

This study aimed to examine the anti-candidal efficacy of a novel ketone derivative isolated from Diaporthe sp. ED2, an endophytic fungus residing in medicinal herb Orthosiphon stamieus Benth. The ethyl acetate extract of the fungal culture was separated by open column and reverse phase high-performance liquid chromatography (HPLC). The eluent at retention time 5.64 min in the HPLC system was the only compound that exhibited anti-candidal activity on Kirby-Bauer assay. The structure of the compound was also elucidated by nuclear magnetic resonance and spectroscopy techniques. The purified anti-candidal compound was obtained as a colorless solid and characterized as 3-hydroxy-5-methoxyhex-5-ene-2,4-dione. On broth microdilution assay, the compound also exhibited fungicidal activity on a clinical strain of Candida albicans at a minimal inhibitory concentration of $3.1{\mu}g/ml$. The killing kinetic analysis also revealed that the compound was fungicidal against C. albicans in a concentration- and time-dependent manner. The compound was heat-stable up to $70^{\circ}C$, but its anti-candidal activity was affected at pH 2.

• Journal of Korean Society of Water and Wastewater
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• v.27 no.4
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• pp.445-456
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• 2013

In this study, desalination by electrodialysis with ion exchange membranes was applied to synthetic waters with various ion concentrations and also for ground waters from coastal areas in Korea. Electrodialysis performance on the synthetic solutions showed the similar tendency in operation time and current curves, i.e., shorter operation time and higher maximum current with increasing applied voltages. The ED results of synthetic waters with different ion compositions, i.e., $Na_2SO_4$, $MgSO_4$, $CaSO_4$, at the similar conductivity condition, i.e., $1,250{\mu}s/cm$ revealed that effects of mono- and divalent ions on water quality and performance in electrodialysis were different. The divalent ions had less efficiency in the ED compared to monovalent sodium ions and also divalent calcium ions showed better performance than Mg ions. The electrodialysis on the ground waters produced high quality of drinking water. The groundwater from SungRoe however showed a buildup of membrane resistance. Organic matter concentrations and great portions of divalent ions in the groundwater were possible causes of the deteriorated performance.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.19 no.4
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• pp.503-510
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• 2012

Purpose: The purpose of this study was to identify the factors influencing emergency department (ED) nurses' turnover intention. Methods: The study was conducted with 241 nurses from ED of 20 general hospitals in Busan. The survey data were collected from May 1 to July 31, 2010 and were analyzed using frequencies, percentages, means, t-test, ANOVA, Pearson correlation coefficient and stepwise multiple regression with the SPSS Win 17.0 program. Results: There were statistically significant differences in turnover intention depending on age, regular change in department, and nursing experiences. A significant positive correlation was found between job stress and turnover intention and a significant negative correlation between organizational commitment and turnover intention. The significant factors influencing turnover intention were regular change in department, job stress, and organizational commitment, which explained about 13.7% of the variance. Conclusion: Considering this results, nursing managers should analyze these main factors which affect turnover intention and create ways to decrease turnover intentions, and thus decrease high turnover intention.

• Research in Community and Public Health Nursing
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• v.27 no.4
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• pp.327-336
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• 2016

Purpose: This study was to examine the clinical characteristics and mortality risk factors of geriatric hospital patients who visited one region-wide emergency department (ED). It's basically meant to develop criteria for the patient management of geriatric hospitals and to provide related information. Methods: A retrospective research study was implemented using electronic medical records. The subjects in this study included 484 geriatric hospital patients who were selected from among 15,994 patients that visited one region-wide ED between January 1, 2014, and December 31, 2015. Results: There were significant differences in death, a change for the better and no change for the better, which were results of treatment, according to the length of stay in hospital, hospitalization in a general ward, not having an operation or surgery, the presence or absence of malignant neoplasm, the insertion of foley catheter, intubation, ventilator and the insertion of central venous catheter. Conclusion: The results of this study suggest that a patient management system is necessary in geriatric hospitals and that competent healthcare workers who can properly respond to emergencies are required as well.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.38 no.1
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• pp.43-53
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• 2001

WT(Wavelet Transform) is used to avoid blocking effect that is the disadvantage of JPEG using DCT(Discrete Cosine Transform). Because the proposed coding scheme is the same as JPEG, the proposed algorithm is compatible with that of JPEG. To achieve the goal, WT'ed image is reconstructed into 8$\times$8 coding block. Each coding block is quantized with the proposed weighting matrix that is derived from human visual characteristic and error analysis in WT'ed domain. By experiments, the proposed algorithm is superior to JPEG, in terms of PSNR(Peak Signal to Noise Ratio) and WMSE(Weighted Mean Square Error).

• Journal of Korean Academy of Fundamentals of Nursing
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• v.17 no.4
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• pp.566-574
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• 2010

Purpose: This study was done to identify the relationship of emergency department(ED) nurse's job characteristics, organizational commitment and turnover intention. Method: This study was conducted through a survey of 171 nurses from ED in nine general hospitals of Band U cities. The data were collected by self-report questionnaires and analyzed with the SPSS WIN 17.0 program using descriptive statistics, t-test, ANOVA, Pearson correlation coefficient and stepwise multiple regression. Results: The mean score for job characteristics was 3.37. Job characteristics according to position, number days night duty, and monthly income showed significant differences. Turnover intention according to age, total career, and monthly income showed significant differences. A significant positive correlation was found between job characteristics and organizational commitment. Significant negative correlations were found between job characteristics and turnover intention, organizational commitment and turnover intention were found. The significant factors influencing turnover intention were organizational commitment, monthly income, and total career, which explained 27.6% of the variance. Conclusion: The findings indicate that nurse managers should analyze the reasons for high turnover intention, focusing on the main factors affecting turnover intention and consider solutions for decreasing turnover intention.