• Title/Summary/Keyword: ECT

Search Result 423, Processing Time 0.03 seconds

A Study on the Human Growth Hormone Response Following Electro Convulsion Therapy (전기-경련 시술후의 혈장 HGH 반응)

  • Kim, Dong-Ju;Sung, Ho-Kyung;Rhee, Sang-Don
    • The Korean Journal of Physiology
    • /
    • v.10 no.1
    • /
    • pp.67-71
    • /
    • 1976
  • Effect of Electro Convulsion Therapy (ECT) on the Human Growth Hormone (HGH) response was observed in 32 cases of various mental illness. The patients were fasting overnight and ECT was induced in the morning by application of $90{\sim}120V$ for a period of $0.1{\sim}0.5\;sec$. In all patients, venous blood samples were taken prior to simultaneously with 1 and 4 hours after the ECT. Plasma was immediately seperated and stored in $-20^{\circ}C$ refrigerator. HGH concentrantion was determined by means of radioimmunoassay Results were as follows: 1. Application of electric current was not followed by a significant change in mean plasma HGH of 52 cases. 2 Increases of plasma HGH following ECT were observed in about half cases showing low initial level but in 20 other cases with high initial level of plasma HGH, reasonable decreases after therapy were not found. 3. Plasma concentration of HGH one hour after application of current were always higher than just after the current. 4. There were no differences between HGH responses to a 1st, 2nd or 5th ECT. 5. Discussions were made on the possible modification of HGH response following ECT by the autoregulatory control mechanism.

  • PDF

Anticonvulsant Effect of Artemisia capillaris Herba in Mice

  • Woo, Tae-Seon;Yoon, Seo-Young;Pena, Ike Campomayor Dela;Choi, Ji-Young;Lee, Hye-Lim;Choi, Yoon-Jung;Lee, Yong-Soo;Ryu, Jong-Hoon;Choi, Jae-Sue;Cheong, Jae-Hoon
    • Biomolecules & Therapeutics
    • /
    • v.19 no.3
    • /
    • pp.342-347
    • /
    • 2011
  • In the present study, the anticonvulsant effects of Artemisia capillaris Herba (AC) and its major constituent, esculetin (ECT), were tested and the mechanism studied. Locomotion, Myorelaxation, motor coordination and electroshock seizure experiment were conducted in mice. To identify the anticonvulsant mechanism effect of this drug, chemical-induced seizure in mice and the ionic movement in neuroblastoma cells were also observed. The ethanol extract of AC was orally administered to mice 30 min. prior to testing and ECT was intraperitoneally injected. AC and ECT treatment did not change locomotor activities as well as activities on the rota-rod, which indicates that they did not cause a sedative and myorelaxation effect. AC and ECT treatment increased threshold of convulsion induced by electroshock. AC treatment also inhibited convulsion induced by pentylenetetrazole. In the case of strychnine however, only high dose of AC treatment inhibited convulsion. AC and ECT treatment increased the $Cl^-$ influx into the intracellular area in a dose-dependent manner. On the other hand, bicuculline, a GABA antagonist, inhibited the $Cl^-$ influx induced by AC and ECT. These results indicate that ECT induces the anticonvulsive effect of AC extract through the GABAergic neuron.

The Defect Inspection on the Irradiated Fuel Rod by Eddy Current Test (와전류시험에 의한 조사핵연료봉의 결함 검사)

  • Koo, D.S.;Park, Y.K.;Kim, E.K.
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.16 no.1
    • /
    • pp.29-33
    • /
    • 1996
  • The eddy current test(ECT) probe of differential encircling coil type was designed and fabricated, and the optimum condition of ECT was derived for the examination of the irradiated fuel rod. The correlation between ECT test frequency and phase & amplitude was derived by performing the test of the standard rig that includes inner notches, outer notches and through-holes. The defect of through-hole was predicted by ECT at the G33-N2 fuel rod irradiated in the Kori-1 nuclear power reactor. The metallographic examination on the G33-N2 fuel rod was Performed at the defect location predicted by ECT. The result of metallographic examination for the G33-N2 fuel rod was in good agreement with that of ECT. This proves that the evaluation for integrity of irradiated fuel rod by ECT is reliable.

  • PDF

Prediction of Defect Size of Steam Generator Tube in Nuclear Power Plant Using Neural Network (신경회로망을 이용한 원전SG 세관 결함크기 예측)

  • Han, Ki-Won;Jo, Nam-Hoon;Lee, Hyang-Beom
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.27 no.5
    • /
    • pp.383-392
    • /
    • 2007
  • In this paper, we study the prediction of depth and width of a defect in steam generator tube in nuclear power plant using neural network. To this end, we first generate eddy current testing (ECT) signals for 4 defect patterns of SG tube: I-In type, I-Out type, V-In type, and V-Out type. In particular, we generate 400 ECT signals for various widths and depths for each defect type by the numerical analysis program based on finite element modeling. From those generated ECT signals, we extract new feature vectors for the prediction of defect size, which include the angle between the two points where the maximum impedance and half the maximum impedance are achieved. Using the extracted feature vector, multi-layer perceptron with one hidden layer is used to predict the size of defects. Through the computer simulation study, it is shown that the proposed method achieves decent prediction performance in terms of maximum error and mean absolute percentage error (MAPE).

Electroconvulsive Therapy for Psychiatric Disorders in Elderly Adults (노년기 정신장애의 전기경련치료)

  • Joo, Eun-Jeong;Kim, Hee Cheol;Kang, Ung Gu;Lee, Nam Young;Park, Seung Hyun;Kim, Jung Min;Kim, Yong Sik;Chung, In Won
    • Korean Journal of Biological Psychiatry
    • /
    • v.27 no.2
    • /
    • pp.42-57
    • /
    • 2020
  • Electroconvulsive therapy (ECT) is indicated for various mental disorders (e.g., major depressive disorder, schizophrenia, and bipolar disorder) and the behavioral and psychological symptoms of dementia in elderly patients. Furthermore, ECT is a useful first-line treatment in emergency and crisis situations such as suicide risk, violent behavior, catatonia, and food refusal, which are more frequent in elderly patients. ECT is also effective in the treatment of the motor symptoms of neurological disorders, such as Parkinson's disease and Huntington's disease. Due to the high risk of various physical diseases, the comorbid physical conditions of elderly patients should be individually controlled to optimize ECT treatment. Compared to young adults, in elderly patients the seizure threshold is higher, the seizure duration is shorter, and the anesthetic dose is lower. On the contrary, the response rate in the elderly is both faster and higher. Considering potential cognitive decline and the prevention of further deterioration of cognitive function in elderly patients, in the absence of significant comorbidities, twice weekly sessions and right unilateral electrode placement with a lower seizure threshold and less cognitive effect are preferred to bilateral electrode placement, which has a high risk of adverse cognitive effects. After an acute course of ECT, continuation and maintenance of ECT, combined with prescription of therapeutic drugs, may prevent possible relapse or recurrence of mental disorders. In conclusion, ECT can be used to treat mental disorders in elderly adults, with safety and effectiveness comparable to that in young adults.

Hedge Effectiveness in Won-Dollar Futures Markets (원 달러 선물시장을 이용한 헤지효과성)

  • Hong, Chung-Hyo;Moon, Gyu-Hyun
    • The Korean Journal of Financial Management
    • /
    • v.21 no.1
    • /
    • pp.231-253
    • /
    • 2004
  • We examine hedge strategies that use Won-dollar futures to hedge the price risk of the Won-dollar exchange rate. We employ the naive hedge model, minimum variance hedge model and bivariate ECT-ARCH(1) model as hedge instruments, and analyze their hedge performances. The sample period covers from January 2, 2001 to December 31, 2002 with sub-samples such as daily, weekly, bi-weekly prices of the Won-dollar futures and cash. The important findings may be summarized as follows. First, there is no significant difference in hedge ratio between the risk minimum variance model and bivariate ECT-ARCH(1) model that controls for the cointegration relationship of the Won-dollar futures and cash. Second, hedge performance of the naive model and minimum variance model with constant hedge ratios is not far behind that of bivariate ECT-ARCH(1) model with time-varying hedge ratios. This results imply that investors are encouraged to use the minimum variance hedge model to hedge Won-dollar exchange rate with Won-dollar futures. Third, hedge performance and effectiveness of each model is also analyzed with respect to hedge period appear to be greater over long than over the short period. This evidence supports the hypothesis that futures prices would have more time to respond to the greater cash price changes over the longer holding period, leading to an improved hedge performance.

  • PDF

Application of Amorphous wire to ECT(Eddy Current Testing) Probe (아몰퍼스 와이어의 ECT probe 적용에 대한 검토)

  • Kim, Y.H.;Shin, K.H.;SaGong, Gun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2002.08a
    • /
    • pp.47-51
    • /
    • 2002
  • ECT(eddy currentign testing) is very effective technique to detect a flaw within a conductor. Co-based amorphous wire was used as a sensor head. The wire has almost 0 magneto-striction and high permeability. An uniform magnetic field was applied to 1mm thick copper plate and $25{\mu}m$ thick aluminum sheet conductor using spiral typed coil The size of the coil has $40mm{\times}40mm$ outer width and $8mm{\times}8mm$ inner width. The copper plate and aluminum sheet has 0.5mm and 0.1mm wide gap, respectively. The frequency range of applied field was 100kHz-600kHz. The induced voltage difference of 2.5mV was obtained in the maximum voltage and minimum one measured across the gap of the 1mm thick conductor. In the case of aluminum sheet, 0.4mV was obtained. From this results, the effectiveness of Co-based amorphous wire was confirmed in the ECT technique.

  • PDF

The application of electrochemotherapy in three dogs with inoperable cancers

  • Yeom, Seung Chul;Song, Kun Ho;Seo, Kyoung Won
    • Korean Journal of Veterinary Research
    • /
    • v.61 no.1
    • /
    • pp.9.1-9.6
    • /
    • 2021
  • Factors such as location, volume, and the type of neoplasm complicate achieving tumor control. Electrochemotherapy (ECT) is a supplementary treatment for inoperable neoplasms in veterinary patients. Three dogs were diagnosed with a tumor. Two were squamous cell carcinoma (SCC), and the other was liposarcoma, each with a single tumor with the size range of 1 to 5 cm. The tumor locations were the cervical, oral, and abdominal cavity. ECT was selected as a treatment. Bleomycin was injected intratumorally at the dose of 0.5 to 1.0 mg/㎤. Five minutes after the injection, electric pulses applied in a sequence of eight pulses lasting 100 μsec each, were delivered in 1,000 V/cm. An evaluation was performed after 1 week, and the next session was administered 2 weeks later. In a patient with oral SCC, the tumor was in partial remission after two sessions of ECT. Another patient with SCC on her neck was showed complete remission after 2 weeks of ECT administration. A third patient showed stable disease for 8 weeks. Complications were mild and transient and included skin necrosis, edema, local pain, and gait disturbance. ECT is a valid adjuvant, especially for inoperable, cutaneous, or accessible intra-abdominal tumors.

Improvement of Plants by Biotechnology (세포공학을 이용한 식물개량)

  • 윤의수
    • Korean Journal of Plant Resources
    • /
    • v.3 no.1
    • /
    • pp.1-30
    • /
    • 1990
  • The traditional plant imprownent methods consisted of pure line selection, cross breeding, heterosis breeding, polyploid breeding, mutati-onbreeding, ect.Biotechmoiogy is divided into gene spliclng , monocle-nal antibodies , protein engineering , agricultural research, and microbiological engineering. Of these , high plants deal with agricultural research, and the importent part of which is tissue culture and celLculture , Tissue .culture and cell culture are again divided into embryoculture, test tube fertilization, anther and pollen culture, somatichybridization , transformation, recombination, recombinant DNA moleculehybrid plasmid, ect For these haploid production, protoplast culture,protoplast fusion, selection and propagation, ect. , the technical sett-lement is needed.

  • PDF

A Bibliographic Study on the Bleeding of Cough (해혈(咳血)에 대(對)한 문헌적(文獻的) 고찰(考察))

  • Lee, Seung-Woo
    • The Journal of Internal Korean Medicine
    • /
    • v.12 no.1
    • /
    • pp.183-188
    • /
    • 1991
  • The following results were obtained according to these fact which is considered peviodically and bibliographically ; 1. The cause of bleeding of cough was Oegampunghan(外感風寒), Pyosaoesok(表邪外束), Chohwasangpye(燥火傷肺) in external cause, Eumhuhwadong(陰虛火動), Sinhu(腎虛), Hyulhu(血虛), Damhwajukyul(痰火積熱), Pyesuyul(肺受熱) ect. in internal cause. 2. The symptoms of bleeding of cough because of external cause was similar to generally cold symptom, because of internal cause were similar to Yeumhuhwadong(陰虛火動) and generanl Huyul(虛熱) symptom. 3. The treatment of external were Mahwangtang, Soshihotang, Sabaeksan ect. internal were Samultang, Yookmijihwangtang, Jaeumganghwatang, Gesosan ect.

  • PDF