• Clinical and Experimental Reproductive Medicine
• /
• 제41권2호
• /
• pp.47-61
• /
• 2014

Stored maternal factors in oocytes regulate oocyte differentiation into embryos during early embryonic development. Before zygotic gene activation (ZGA), these early embryos are mainly dependent on maternal factors for survival, such as macromolecules and subcellular organelles in oocytes. The genes encoding these essential maternal products are referred to as maternal effect genes (MEGs). MEGs accumulate maternal factors during oogenesis and enable ZGA, progression of early embryo development, and the initial establishment of embryonic cell lineages. Disruption of MEGs results in defective embryogenesis. Despite their important functions, only a few mammalian MEGs have been identified. In this review we summarize the roles of known MEGs in mouse fertility, with a particular emphasis on oocytes and early embryonic development. An increased knowledge of the working mechanism of MEGs could ultimately provide a means to regulate oocyte maturation and subsequent early embryonic development.

• 한국생활과학회지
• /
• 제13권4호
• /
• pp.497-506
• /
• 2004

This study examines the influence of early English education on children's bilingual language development to see whether the early exposure to English education affects children's competencies of both English and Korean. Based on this purpose, it attempts to examine whether it supports additive or subtractive bilingualism. The competencies of both English and Korean of the children with early English education were, therefore, compared with those of the children without it, and the relation between the two competencies was also studied. For this research, two different groups of children - one with 48 children who attend English kindergarten and the other with 60 children who attend only Korean kindergarten - took PPVT-R in Korean and in English each. The result shows that children with early English education have more English competency than those without it. No significant differences, however, are found in Korean competency between the two groups. The relation between the two competencies proves positive in children with early English education. It can thus be concluded that the effect of early English education is partially positive on children's language development, which may support the additive bilingualism that children's second language can improve without losing their native language competency. In addition, this result will be able to provide for us the direction and the guideline to the policy of foreign language education and early education.

• 영어어문교육
• /
• 제17권2호
• /
• pp.79-91
• /
• 2011

The purpose of this paper was to take an in-depth look at early American English around the $17^{th}$ and $18^{th}$ century when immigrants from different European countries started to move into the New World. The paper attempted to describe early American English in relation to the process of immigration and settlement from a historical perspective. With a focus on major features of early American English such as uniformity, archaism and richness of lexicon, the paper tried to answer the questions such as how settlement influenced the formation and distribution of regional dialects across the continent, why immigrants tended to show a preference for a uniform way of speaking rather than choosing a variety of regional dialects for communication, and what role foreign languages played in the development of early American English. The overall findings based on the answers to these questions showed how American English went through a variety of processes and changes at the early stages of its development to become a national language later. The paper concluded with some remarks about the implications of the findings for EFL learning and the direction of future research on early American English.

• 한국건축시공학회:학술대회논문집
• /
• 한국건축시공학회 2013년도 추계 학술논문 발표대회
• /
• pp.80-81
• /
• 2013

There is the increasing number of constructing soil or structure on the soft ground during public works. Usually cement or slag cement has been the traditional material for surface soil stabilization method. Recently, early strength development properties of hardening agent is required for driving abilities of execution equipment and shortening of the construction time. Therefore, the purpose of this study is to develop the early compressive strength hardening agent for surface soil stabilization. The study was confirmed performance and availability of hardening agent using early strength type cement and industrial by-product minerals through early strength development properties in accordance with water cement ratio, content of hardening agent for soft soil.

• 한국보육지원학회지
• /
• 제12권2호
• /
• pp.113-125
• /
• 2016

This study examined the effects of constructivist educational beliefs and self-regulated learning skills of children on teacher professional development. The study was conducted by sampling 273 teachers. Three kinds of variables, which included constructivist educational beliefs, self-regulated learning ability, and professional development level were measured and analyzed for this study. The results were as follows. First, early childhood teachers beliefs of constructivist education, self-regulated learning ability and professional development were found to be higher than average. Second, the professional development of early childhood teachers is shown to be correlated with constructivist educational beliefs and self-regulated learning ability. When constructivist educational beliefs and self-regulated learning ability scores increases, the professional development score is high. Third, metacognitive strategies, cognitive strategies and constructivist educational beliefs are factors that predict the professional development of early childhood teachers. According to results of this study, it suggests that constructivist educational beliefs and self-regulated learning ability are important factors to be addressed.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2003년도 가을 학술발표회 논문집
• /
• pp.269-272
• /
• 2003

This study is intended to investigate the properties of concrete using AE Water Reducing Agent of Early-Strength Type. According to the results, as for the replacing method of mineral admixture, setting time is shortened faster in order of replacement for fine aggregate, combination and replacement for cement, and when AE Water Reducing Agent of Early-Strength Type is used, it is shortened by about 4 hours, compared with normal AE Water Reducing Agent Compressive strength is lower in the case of replacement for fine aggregate, but higher in the other case than that of plain concrete. And When AE Water Reducing Agent of Early-Strength Type is used, early compressive strength is very high in comparison to normal AE Water Reducing Agent. Early strength development is very favorable by the use of AE Water Reducing Agent of Early-Strength Type regardless of the replacing method of mineral admixture at $20^{\circ}C$, but at $l0^{\circ}C$, it is effective for Early strength development that W/B is lowered to below 45%, BS of 20% is replaced for fine aggregate, and AE Water Reducing Agent of Early-Strength Type is used.

• 한국환경보건학회지
• /
• 제35권6호
• /
• pp.486-490
• /
• 2009

In January 2009, the water quality of offshore around the Incheon coast was evaluated by bioassay using early development systems of a sea urchin species, Hemicentrotus pulcherrimus. The results of performing biological evaluations on seawater samples from total of thirteen sites, showed that the formation rates of normal pluteus larva varied from 18% to 71%. In site 5 the seawater sample led to an averaage formation rate of normal larva of 18%, the highest abnormal formation rate hindering the early embryo development of the experimental animal, while that of site 3 averaged 71%, the highest formation rate of normal larva. Seawater samples from site 1, 2, 4, 7, 9, 10, 11 and 12, resulted in average formation rates of normal larva from 33% to 56%, which indicates the developmental damage of early embryos is not severe. Seawater samples from site 5, 6, 8 and 13, resulted in average formation rates of normal larva from 18% to 21% which there was strong damage to the development of early embryos.

• 한국보육지원학회지
• /
• 제7권4호
• /
• pp.223-252
• /
• 2011

커리어 포트폴리오를 활용한 예비유아교사 전문성 강화 프로그램은 예비유아교사들에게 이상적인 유아교사의 삶을 찾기 위한 다양한 경험을 제공함으로써 교사로서의 교육신념을 확립하고 자신의 능력에 대한 객관적인 통찰을 하게 할 뿐 아니라 지속적인 자기반성 그리고 자기 계발을 가능하게 하는 것을 목적으로 한다. 본 연구는 커리어 포트폴리오를 활용한 교사교육 프로그램을 교사교육현장에 적용함으로써 프로그램의 효과를 검증하고 이후 바람직한 현장 적용을 위한 시사점을 제안하는 것을 목적으로 한다. 연구의 목적을 달성하기 위하여 유아교육과 재학생 26명을 대상으로 8주간 프로그램을 적용하였으며 적용과정에서 수집된 양적 질적 자료 모두에서 예비유아교사의 전문성 강화에 긍정적인 효과가 있음을 알 수 있었다. 또한 적용된 프로그램이 예비유아교사의 전문성 강화를 위한 원동력을 갖추어 줄 수 있을 뿐 아니라 이를 통해 최근 이슈가 되고 있는 유아교사 양성과정의 많은 문제점들을 극복할 수 있는 바람직한 해결방안이 될 수 있음을 확인할 수 있었다.

• 한국보육지원학회지
• /
• 제19권2호
• /
• pp.87-117
• /
• 2023

Objective: This study aimed to develop a documentation model that can support early chlildhood learning through play and facilitate the implementation of early childhood and play-oriented curriculum. Methods: This study utilized the design and development research methodology to derive components for the model through literature review and investigation research. In addition, the model was gradually improved through the 3rd expert review, and the validity of the model was verified through usability evaluation with 10 early childhood teachers. Results: This study identified 13 components and developed a flexible, selective, repetitive, and cyclic documentation model based on the 2019 revised Nuri curriculum. Model development is embodied and presented as a model-detailed model-detailed content. The model is presented in detail in the study. Conclusion/Implications: The documentation model developed in this study is expected to provide guidance to early childhood teachers and serve as a basis for future research on documentation in early childhood education. It is expected that it will be able to present the practical direction of records for play support for teachers in the field.

• Toxicological Research
• /
• 제18권2호
• /
• pp.167-174
• /
• 2002

Historical control data have been shown to be valuable in the proper interpretation and validation of reproductive toxicology studies. The present data were compiled from rat fertility and early embryonic development studies conducted at Korea Institute of Toxicology during the 1994∼2001 period. These data were assembled in order to provide background information for the general and reproductive data collected in 11 fertility and early embryonic development studies using Sprague-Dawley rats obtain-ing from the Breeding Facility, Korea Institute of Toxicology, Korea. A total of 274 males and 274 females were used in these studies during the eight-year period. Parameters of fertility and early embryonic development included clinical sign, body weights, food consumption, organ weights, estrus cycle, copulation index, precoital time, fertility index, pregnancy index, sperm parameters, and early embryonic development parameters. Most of the values were comparable to the previous historical control data reported by other investigators. These data can be wed not only as a historical data base for the meaningful interpretation of data from reproductive and developmental toxicity studies, but also as a contribution to biological characterization of Sprague-Dawley rats.